As filed with the Securities and Exchange Commission on February 20, 2024

Registration No. 333-          

 

 

UNITED STATES SECURITIES AND EXCHANGE
COMMISSION

Washington, D.C. 20549

 

 

 

FORM S-8

 

REGISTRATION STATEMENT

Under

THE SECURITIES ACT OF 1933

 

 

 

ASTRAZENECA PLC

(Exact name of registrant as specified in its charter)

 

England and Wales
(State or other jurisdiction of
incorporation or organization)
  Not Applicable
(I.R.S. Employer
Identification No.)

 

1 Francis Crick Avenue

Cambridge Biomedical Campus

Cambridge CB2 0AA

England

(Address of principal executive offices)

 

 

 

ASTRAZENECA GLOBAL RESTRICTED STOCK PLAN

(Full title of the plan)

 

CT Corporation System

28 Liberty Street

New York, NY 10005

Tel: +1-212-894-8940

(Name, address and telephone
number of agent for service)

 

 

 

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act. (Check one)

 

x Large accelerated filer ¨ Accelerated filer ¨ Non-accelerated filer ¨ Smaller reporting company
       
      ¨ Emerging growth company

 

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ¨

 

 

 

 

 

 

EXPLANATORY NOTE

 

This Registration Statement on Form S-8 (this “Registration Statement”) registers an additional 20,000,000 Ordinary Shares, par value $0.25 each (“Ordinary Shares”), of AstraZeneca PLC (the “Company”), represented by an additional 40,000,000 American Depositary Shares, each representing one half of one Ordinary Share (“ADSs”), that may be offered or sold pursuant to an increase in the number of Ordinary Shares that may be awarded under the AstraZeneca Global Restricted Stock Plan (the “GRSP”), as amended by the Remuneration Committee of the Company’s Board of Directors on December 13, 2023. The GRSP provides that Ordinary Shares or ADSs will be purchased by the trustee of the GRSP for the accounts of the participants on the open market. The GRSP does not provide for Ordinary Shares to be issued by the Company out of its authorized and unissued Ordinary Shares. The additional securities are of the same class as other securities relating to the GRSP for which the Company’s Registration Statement on Form S-8 (File No. 333-240298) filed on August 3, 2020 (the “Prior Registration Statement”) is effective. The information contained in the Prior Registration Statement is hereby incorporated by reference pursuant to General Instruction E to Form S-8.

 

PART II

 

INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

 

Item 5. Interests of Named Experts and Counsel.

 

Not applicable. Because no original issuance securities are to be registered hereunder, no opinion of counsel regarding the legality of the securities being registered hereunder is required pursuant to Item 8(a)(i) of Form S-8.

 

Item 8. Exhibits.

 

Exhibit
No.
  Description
4.1   Articles of Association (incorporated herein by reference to Exhibit 99.1 to Form 6-K filed by the Company on April 27, 2023 (File No. 001-11960)).
     
4.2   Form of Amended and Restated Deposit Agreement, by and among AstraZeneca PLC, Deutsche Bank Trust Company Americas, as depositary, and all holders and beneficial owners from time to time of ADSs issued thereunder (including as an exhibit thereto the form of American Depositary Receipt) (incorporated herein by reference to Exhibit (a) to Form F-6 filed by the Company on January 22, 2020 (File No. 333-236014)).
     
4.3   Form of American Depositary Receipt (included in Exhibit 4.2).
     
4.4   AstraZeneca Global Restricted Stock Plan.*
     
23.1   Consent of PricewaterhouseCoopers LLP, independent registered public accounting firm.*
     
24.1   Power of Attorney (see signature page hereto).*
     
107   Filing Fee Table.*

 

 

* Filed herewith

 

 1 

 

 

SIGNATURES

 

Pursuant to the requirements of the Securities Act, AstraZeneca PLC certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized in London on February 20, 2024.

 

  ASTRAZENECA PLC 
     
  By  /s/ Adrian Kemp
    Name:  Adrian Kemp 
    Title:  Company Secretary 

 

POWER OF ATTORNEY

 

KNOW ALL PERSONS BY THESE PRESENTS that each person whose signature appears below hereby constitutes and appoints Adrian Kemp and Matthew Bowden (with full power to each of them to act alone), as such person’s true and lawful attorney-in-fact and agent, with full power of substitution and resubstitution, for such person and in such person’s name, place and stead, in any and all capacities, to sign and file with the Securities and Exchange Commission any and all amendments and post-effective amendments to this Registration Statement, with exhibits thereto and any and all other documents that may be required in connection therewith, granting unto each said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as might or could do in person, hereby ratifying and confirming all that each said attorney-in-fact and agent, or any substitutes therefor, may lawfully do or cause to be done by virtue hereof.

 

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed below by the following persons in the capacities and on the dates indicated.

 

Name    Title    Date 

 

/s/ Pascal Soriot

  Executive Director and Chief Executive Officer   February 20, 2024 
Pascal Soriot   (Principal Executive Officer)    
         
/s/ Aradhana Sarin   Executive Director and Chief Financial Officer   February 20, 2024 
Aradhana Sarin   (Principal Financial Officer)    
         
/s/ Mani Sharma   SVP, Group Financial Controller   February 20, 2024 
Mani Sharma   (Principal Accounting Officer)    
         
/s/ Michael Demaré   Non-Executive Chairman of the Board    February 20, 2024 
Michael Demaré        
         
/s/ Philip Broadley   Senior Independent Non-Executive Director    February 20, 2024 
Philip Broadley        
         
/s/ Euan Ashley   Non-Executive Director    February 20, 2024 
Euan Ashley        
         
/s/ Deborah DiSanzo   Non-Executive Director    February 20, 2024 
Deborah DiSanzo  

 

   
         
/s/ Diana Layfield   Non-Executive Director    February 20, 2024 
Diana Layfield        
         
/s/ Anna Manz   Non-Executive Director    February 20, 2024 
Anna Manz        
         
/s/ Sheri McCoy   Non-Executive Director    February 20, 2024 
Sheri McCoy        
         
/s/ Tony Mok   Non-Executive Director    February 20, 2024 
Tony Mok        
         
/s/ Nazneen Rahman   Non-Executive Director    February 20, 2024 
Nazneen Rahman        
         
/s/ Andreas Rummelt   Non-Executive Director    February 20, 2024 
Andreas Rummelt        
         
/s/ Marcus Wallenberg   Non-Executive Director    February 20, 2024 
Marcus Wallenberg        

 

Authorized Representative        
         
/s/ Mariam Koohdary       February 20, 2024 
Mariam Koohdary, as duly authorized representative of AstraZeneca PLC in the United States        

 

 2 

 

 

Exhibit 4.4

 

Plan Rules of the AstraZeneca Global Restricted Stock Plan

Adopted by RemCo on 1 March 2010 and restated on 22 October 2019 and amended on 25 September 2020, 27 April 2022

and 13 December 2023. Plan terminates on 22 October 2029

French Appendix terminates on 22 February 2026

 

AstraZeneca Global Restricted Stock Plan

 

What is an ‘award’ and when do you get shares?

 

An award under the Plan is a contingent right to receive shares in AstraZeneca PLC. When your award ‘vests’ you receive shares.

 

Your award will normally vest a specified number of years after grant. After your award vests, you will receive a net number of shares after withholdings for tax have been made. Your shares will be transferred into a nominee or custodian arrangement for you.

 

What happens if you leave?

 

Awards will generally only vest if you are employed. If you leave AZ within the specified number of years after grant, your unvested awards will normally lapse.

 

However, if you end employment for one of the following reasons:

 

(a)death,

 

(b)ill-health, injury or disability (in each case evidenced to the satisfaction of your employer),

 

(c)redundancy (within the terms of the Employment Rights Act 1996),

 

(d)circumstances determined by RemCo to be retirement, or

 

(e)the company or business in which you are employed ceasing to be a member of the AZ group,

 

your award will not lapse and it will normally vest on the date you cease employment, pro- rated for the time you were in employment.

 

Change of control of AstraZeneca

 

If there is a change in control of AZ, your award will vest pro-rata (subject to achievement of any performance targets).

 

Dividends

 

On vesting, you will receive cash or additional shares to reflect any dividends that would have been paid to you had you held the shares that vest on any dividend record dates during the Vesting Period (dividend equivalents).

 

General

 

Awards are personal to you and may not be transferred or charged until they vest. The awards do not form part of your terms and conditions of employment and are not pensionable.

 

You may be required to acknowledge the grant of your award and agree to certain terms.

 

This summary does not form part of the Rules of the GRSP. The Rules of the GRSP are set out in the following pages and will govern how your awards are treated. Definitions and interpretation provisions are at Appendix 1. If you are resident in a country outside of the UK, your award may be subject to special terms.

 

 

 

 

Rules of the AstraZeneca Global Restricted Stock Plan

 

1.Grant of Awards

 

RemCo may approve the grant of Awards to Eligible Employees, subject to the limits in Rule 10. Awards will not be granted during a Closed Period.

 

2.Vesting of Awards

 

2.1Vesting of your Award is subject to such terms and conditions as RemCo considers appropriate before grant.

 

2.2Unless your Award vests early under Rules 3 or 7, your Award will vest on the Vesting Date to the extent that any terms and conditions imposed under Rule 2.1 have been met.

 

3.End of Employment

 

3.1If you end Employment before the Vesting Date other than in any of the circumstances set out in Rule 3.2, your Award will lapse unless RemCo in its absolute discretion decides otherwise, in which case RemCo has discretion to decide when and to what extent your Award may vest.

 

3.2If you end Employment before the Vesting Date for one of the following reasons:

 

3.2.1death;

 

3.2.2ill-health, injury or disability (in each case evidenced to the satisfaction of your employing company);

 

3.2.3redundancy within the terms of the Employment Rights Act 1996;

 

3.2.4circumstances determined by RemCo, or anyone authorised by RemCo, to be retirement; or

 

3.2.5the company by which you are employed ceasing to be a member of the AZ Group, or the part of the business in which you are employed being transferred to a person outside the AZ Group,

 

your Award will vest on the date you end Employment, and will be reduced pro- rata to the proportion of the Vesting Period that has elapsed up to the end of Employment, unless RemCo decides not to pro-rate or to pro-rate on some other basis.

 

3.3For the purposes of this Rule 3, if you are on statutory family-related leave, you will not end Employment until the earlier of the date on which you notify your employer of your intention not to return to work or the date on which you cease to have statutory or contractual rights to return to work.

 

3.4If you are resident in China and you end Employment as a result of your death, if a delay in providing the necessary documentation will result in a breach of the Chinese State Administration of Foreign Exchange requirements, your Award shall not be satisfied by the issue or transfer of Shares but will be satisfied by the payment of a cash sum equal to the value of the Shares in respect of which your Award vested under Rule 3.2 (converted into your relevant payroll currency at an appropriate spot rate) less deductions for Tax Liabilities.

 

 

 

 

4.Lapse of Awards

 

4.1Notwithstanding any other provision of these Rules, your Award will lapse:

 

4.1.1if you are declared bankrupt or are unable to hold your Award by operation of law, or you attempt to transfer, assign, charge or dispose of your Award contrary to Rule 12.3;

 

4.1.2to the extent that: (i) the Award does not vest in full under Rules 3 or 7; or (ii) the number of Shares which are subject to the Award is reduced under Rule 8.

 

5.Consequences of Vesting of an Award

 

5.1After vesting of your Award, the number of Shares in respect of which it has vested will, subject to Rule 6, be transferred to you as soon as practicable. Your Shares may be transferred into any nominee or other custodian arrangement as AZ shall determine is appropriate (Shareholding Arrangement) and will be held on your behalf on the terms notified to you from time to time.

 

5.2In the event that you end Employment, unless your Shares are required by AZ to be retained in the Shareholding Arrangement, you will be required to remove your Shares from such Shareholding Arrangement within six months of the date you end Employment. If your Shares remain in the Shareholding Arrangement at the end of that six month period, AZ will have the right, at any time, to sell or direct the sale of your Shares on your behalf at the prevailing market rate and will remit the cash proceeds to you or to an account with a nominee or custodian on your behalf. For the avoidance of doubt, Shares in this Rule 5.2 shall refer to Shares acquired on vesting of your Award, including pursuant to Rule 5.4, and any additional Shares that are acquired by you as a result of your holding of such Shares, for example by way of reinvestment of dividends paid on such Shares.

 

5.3You will have no voting, dividend or other rights in the Shares under your Award before the Vesting Date. Shares that you acquire under the Plan will not have the benefit of any rights that attach to those Shares by reference to a record date that is earlier than the date when you acquired them.

 

5.4To the extent that your Award vests you may receive an additional amount as “dividend equivalents”. Unless RemCo decides otherwise, your dividend equivalents will be calculated by reference to the dividends paid or which are payable on the number of Shares that vest, as if those dividends had been reinvested in Shares on the relevant dividend record dates during the Vesting Period, or if your Award vests early, until the date of such vesting. This payment will be made in cash or Shares, subject to deductions for Tax Liabilities, after your Award has vested, but no later than 15 March after the calendar year in which your Award has vested.

 

 

 

 

5.5Notwithstanding any other provision, RemCo may, at any time, determine that your Award shall not be satisfied by the issue or transfer of Shares but will be satisfied by the payment to you of a cash sum equal to the value of the Shares in respect of which your Award vests on the day of vesting (converted into your relevant payroll currency at an appropriate spot rate) less deductions for Tax Liabilities.

 

6.Tax

 

By accepting the Award, you indemnify AZ and your employer against any Tax Liabilities that may arise in connection with the benefits delivered under the Plan. AZ or your employer may withhold any amount and make any arrangements it considers necessary to meet any Tax Liabilities, which may include the sale on your behalf of any Shares acquired by you under the Plan.

 

7.Change of Control of AZ

 

7.1If before the Vesting Date of an Award:

 

7.1.1an offeror (alone or with any party acting in concert with the offeror) obtains Control of AZ by making an offer to acquire the whole of the issued ordinary share capital of AZ (or any part of it which is not owned by the offeror and any party acting in concert with the offeror);

 

7.1.2the Court sanctions a compromise or arrangement affecting the Shares under section 899 of the Companies Act 2006; or

 

7.1.3a resolution is passed for the voluntary winding up of AZ,

 

unless Rule 7.4 applies, your Award will vest on the date of that event, to the extent decided by RemCo under Rule 7.2.

 

7.2Where Rule 7.1 applies or is likely to apply, an Award will vest pro-rata to the time which has elapsed between the Date of Grant of the Award and the date of the relevant event (subject to achievement of any applicable performance targets, in the opinion of RemCo, at the time of the relevant event or most practicable earlier date). However, RemCo may decide to take into account any other factors it believes to be relevant in determining the extent to which an Award will vest in circumstances it considers exceptional.

 

7.3RemCo will confirm the extent (if any) to which an Award will vest under Rule 7.2. Confirmation may be before, but conditional on, the relevant event in Rule 7.1.

 

7.4If a company obtains Control of AZ, but the shareholders of the acquiring company immediately after it has obtained Control of AZ are substantially the same as the shareholders of AZ immediately before that event, and if the acquiring company consents to this Rule 7.4 applying, then your Award will not vest under Rule 7.1. Instead, it will be exchanged for a new award in respect of shares having a total Market Value being equal to the Market Value of the Shares that are subject to your Award immediately before the exchange. The new award will be governed by the Rules, except that references to Shares shall refer to shares in the acquiring company, and references to AZ shall refer to the acquiring company.

 

 

 

 

8.Malus and Clawback

 

Notwithstanding any other provision, Awards are subject to the Malus and Clawback Global Standard and by accepting an Award, you agree to be bound by the terms of the Malus and Clawback Global Standard.

 

9.Amending the Plan and Awards

 

9.1If there is a Variation in the equity share capital of AZ, the number and/or the nominal value of the Shares over which your Award is granted will be adjusted as RemCo decides. You will be notified of any adjustment under Rule 9.1.

 

9.2AZ can amend these Rules at any time.

 

9.3AZ can adopt additional sections of these Rules applicable in any jurisdiction under which Awards may be subject to additional and/or modified terms and conditions, taking into account any securities, exchange control or taxation laws, which may apply to you, AZ, or any member of the AZ Group. Any additional sections must conform to the basic principles of the Plan and must not exceed the limits set out in these Rules.

 

10.Limit on the number of Shares which can be issued

 

10.1Any Shares you receive on vesting will be Shares that are purchased by the Trustee in the market, and will not be Shares that are treasury shares or are newly issued to you or the Trustee.

 

10.2Unless RemCo decides otherwise, the maximum Market Value of Shares (determined at the Date of Grant) which may be subject to any Award in respect of any Eligible Employee in any financial year of AZ will be 500% of the Eligible Employee's basic salary.

 

11.Administration

 

11.1The Plan will be administered by RemCo which will interpret and construe any provision of the Plan and may adopt any regulations for administering the Plan and any documents it thinks appropriate. The decision of RemCo on any matter concerning the Plan will be final and binding.

 

11.2Any communication in connection with the Plan (including any award documentation) can be given electronically by e-mail or on an online portal designed for the purpose or by personal delivery or post, (in the case of a company, to its registered office and in the case of an individual to the individual's last known address) or by any other means which AZ and you use to communicate with each other.

 

11.3Any notice under the Plan will be given: (i) if delivered personally, at the time of delivery; (ii) if posted, at 10.00 a.m. on the third business day after it was put into the post; or (iii) if sent by e-mail or any other form of electronic delivery system, at the time of despatch.

 

 

 

 

12.General

 

12.1You can reject an Award in writing within thirty (30) days after the Date of Grant. If you do not reject your Award, you will be deemed to have accepted it and its terms. If you reject your Award it will be taken never to have been granted.

 

12.2You may be required to acknowledge the grant of your Award and its terms, in which case AZ will notify you of this requirement. If you fail to acknowledge any Award, RemCo shall have the discretion to apply any additional conditions to the vesting of your Award or Shares received on vesting of your Award as it may determine.

 

12.3Your Award may not be sold, transferred, assigned, charged or otherwise encumbered or disposed of to any person, other than to your personal representatives on your death.

 

12.4Participation in the Plan is not pensionable and does not form part of your employment contract. Nothing in the Plan or any document under it will give any person any right to participate in the Plan and the grant of an Award does not create any right or expectation to the grant of an Award in the future. Your rights and obligations under the terms of your office or Employment will not be affected by your participation in the Plan or any right which you may have to participate under it.

 

12.5By accepting and not rejecting an Award under the Plan, you waive all and any rights to compensation or damages under the Plan in consequence of any loss of rights under the Plan as a result of: (i) termination of your office or Employment with a member of the AZ Group for any reason; or (ii) the way in which RemCo or any person to whom RemCo has delegated authority, exercises or does not exercise any discretion under the Plan. Nothing in the Plan or in any document executed under it will give you any right to continue in Employment or will affect the right of any member of the AZ Group to terminate your Employment without liability at any time with or without cause.

 

12.6The invalidity or non-enforceability of one or more provisions of the Plan will not affect the validity or enforceability of the other provisions of the Plan, which will remain in full force and effect.

 

12.7The Plan was adopted by RemCo on 1 March 2010 and restated on 22 October 2019 and amended on 25 September 2020, 27 April 2022 and 13 December 2023. The Plan will terminate on 22 October 2029 or at any earlier time AZ decides. Termination of the Plan will not affect your Awards.

 

12.8Nothing in this Plan confers any benefit, right or expectation on a person who is not an Eligible Employee or member of the AZ Group, and no third party has any rights under the Contracts (Rights of Third Parties) Act 1999 to enforce any term of this Plan. This does not affect any other right or remedy of a third party which may exist.

 

12.9These Rules will be governed by and construed in accordance with the law of England. You, AZ and any member of the AZ Group submit to the jurisdiction of the English courts in relation to anything arising under the Plan. RemCo may determine that another law will apply to the operation of the Plan outside the United Kingdom.

 

 

 

 

Appendix 1

 

Definitions and Interpretation

 

ADS means an American Depository Share representing Shares;

 

Award means a contingent right to acquire Shares granted or proposed to be granted under Rule 1;

 

AZ means AstraZeneca PLC (registered number 2723534);

 

AZ Group means AZ and any subsidiary, holding company or subsidiary of a holding company of AZ (as each term is defined in section 1159 Companies Act 2006);

 

Closed Period means a period when you are prohibited from dealing in Shares under the UK Market Abuse Regulation, the Criminal Justice Act 1993, or under any other statute, regulation or similar code to which AZ is subject or other share dealing code adopted by AZ from time to time;

 

Control shall have the meaning given in section 995 Income Tax Act 2007;

 

Date of Grant means with respect to an Award, the date on which the Award is granted;

 

Dealing Day means a day on which the London Stock Exchange plc is open for the transaction of business;

 

Eligible Employee means any person who at a Date of Grant is an employee of any member of the AZ Group but not an executive director of AZ;

 

Employment means employment as an employee of any member of the AZ Group;

 

Malus and Clawback Global Standard means the malus and clawback global standard approved by RemCo and which came into effect on 1 December 2023, as amended from time to time;

 

Market Value means, in relation to a Share on any day, an amount equal to the average of the middle market closing prices of a Share (as derived from the Daily Official List of the London Stock Exchange plc) on the three consecutive Dealing Days preceding that day (or such other Dealing Day or Dealing Days as RemCo may decide) or, in the case of an ADS, by reference to the average of the equivalent price of an ADS as derived from NASDAQ on trading days as close as possible to those Dealing Days. In the event that the Shares cease to be traded on the Main Market of the London Stock Exchange and are admitted to trading on a replacement market, references to the Daily Official List of the London Stock Exchange plc shall be construed as references to the equivalent of such replacement market. In the event that ADSs cease to be traded on NASDAQ and are admitted to trading on a replacement market, references to NASDAQ shall be construed as references to such replacement market;

 

Plan means the AstraZeneca Global Restricted Stock Plan constituted by these Rules;

 

 

 

 

RemCo means the duly authorised remuneration committee of the board of directors of AZ;

 

Share means a fully paid ordinary share in the capital of AZ or, where the context requires it, an equivalent number of ADSs;

 

Shareholding Arrangement means the nominee or custodian arrangement referred to in Rule 5.1;

 

Tax Liabilities means any income tax, employee’s national insurance contributions, social security charges or similar taxes or charges imposed in any jurisdiction for which AZ or any member of the AZ Group is required to account;

 

Trustee means the trustee for the time being of an employee benefit trust established by AZ;

 

Variation means a capitalisation issue, rights issue, subdivision, consolidation, reduction, or any other variation in the capital of AZ;

 

Vesting Date means in relation to an Award the date specified at the Date of Grant, save that if such date falls within a Closed Period, unless RemCo has made a determination under Rule 5.5, the Vesting Date will be the first Dealing Day following the end of that Closed Period;

 

Vesting Period means in relation to an Award, the period between the Date of Grant of the Award and the Vesting Date; and

 

you means any Eligible Employee to whom an Award has been granted, or (where the context requires) that Eligible Employee's personal representatives, and “your” shall be construed accordingly.

 

Interpretation

 

Headings are for convenience only. Words in the singular include the plural and vice versa and words importing gender include both genders. Reference to statutory provisions include amendments, extensions or re-enactments and equivalent legislation in any country other than England, and include any regulations or subordinate legislation made under them.

 

 

 

 

Appendix 2

 

Schedule for US Participants

 

The provisions of sections 1 to 5 of this Schedule modify the Rules of the Plan in respect of any Awards granted under it to Eligible Employees who are resident in the United States.

 

1.The following shall be inserted as new Rule 2.3:

 

"You may be required, as a condition of the vesting of your Award, to represent and agree that, in relation to Shares you acquire under the Plan:

 

(a)you understand that such Shares are deemed to be restricted securities within the meaning of Rule 144 under the United States Securities Act of 1933 (the “Securities Act”), which may not be resold in the United States or to a U.S. person except pursuant to an effective registration statement under the Securities Act or an exemption from the registration requirements of the Securities Act;

 

(b)you are acquiring such Shares for investment and not with a view to distribution; and

 

(c)you will not resell such Shares at any time, except to non-U.S. persons in transactions effected in accordance with Rule 904 of Regulation S under the Securities Act (or any successor section thereto) and only after the expiration of any holding period RemCo may require.

 

AZ may endorse on certificates representing Shares issued or transferred upon the vesting of an Award such legend referring to the foregoing representations or restrictions or any other applicable restrictions on resale as AZ, in its discretion, shall deem appropriate.”

 

2.In the definition of “AZ Group”, “subsidiary” shall be defined as any company in which AZ owns, directly or indirectly, a majority of the voting rights.

 

3.In Rule 3.2.3, the words "redundancy within the terms of the Employment Rights Act 1996" shall be deleted and replaced by "Redundancy”.

 

4.In Rule 3.2.4, the words "circumstances determined by RemCo, or anyone authorised by RemCo, to be retirement" shall be deleted and replaced by "Retirement".

 

5.In Appendix 1 (Definitions) the following definitions shall be inserted:

 

Redundancy means a qualifying involuntary termination without cause (but excluding a termination by mutual agreement or mutual consent) entitling you to a severance payment under a severance program adopted by your U.S. employing company. Vesting under these Rules following your redundancy termination is subject always to your having met all the requirements of such severance program, including having executed a valid release of all and any claims against the AZ Group;”

 

 

 

 

Retirement means:

 

(a)termination without cause after having attained age 62 with 5 years of service;

 

(b)termination without cause after having attained age 65 with 3 years of service; or

 

(c)any other meaning as may be notified to you in writing at the time of grant of your Award;”.

 

The remaining provisions of this Schedule modify the Rules of the Plan in respect of any Awards granted under it to Eligible Employees who are US taxpayers (whether or not they are also resident in the United States).

 

6.Rule 2.2 shall be deleted and replaced with the following:

 

“Subject to Rules 3, 7 and 8, your Award will vest on the Vesting Date, to the extent that any terms and conditions imposed under Rule 2.1 have been met. For the avoidance of doubt, you shall have no rights in respect of the Shares the subject of an Award until the Award has vested. If vesting of an Award would be prohibited by a Closed Period, the day on which the Award vests will be the first Dealing Day on which such prohibition ceases to apply or, if later, the first day on which you are able to trade in the Shares after the Closed Period ceases. In any event, the latest day by which the Shares subject to an Award will be delivered to you is the US Taxpayer Payment Deadline (as defined in Rule 5.1 (as inserted by paragraph 7 of this Appendix 2)).”

 

7.Rule 5.1 shall be deleted and replaced with the following:

 

“After vesting of your Award, the Shares subject to such an Award in respect to which it has vested will, subject to Rule 6, be delivered to you as soon as practicable following the vesting of the Award, but in no event later than the end of the year in which the applicable vesting date occurs, or, if later, by the 15th day of the third month following the applicable vesting date (collectively, the “US Taxpayer Payment Deadline”). You will not be permitted, either directly or indirectly, to designate the year of payment. In the event that an Award vests by reason of Redundancy and your termination of Employment occurs in the calendar year preceding the deadline for you to execute and submit a valid release of claims (if any) required by the applicable severance program, then the year of payment will be the year of the release deadline regardless of whether you earlier submit the release.”

 

“Your Shares may be transferred into any nominee or other custodian arrangement as AZ shall determine is appropriate (Shareholding Arrangement) and will be held on your behalf on the terms notified to you from time to time.”

 

8.Rule 5.4 shall be deleted and replaced with the following:

 

“To the extent that your Award vests, you may, at the discretion of RemCo, receive an amount equivalent to the total dividends paid or which are payable on the number of Shares that vest, by reference to dividend record dates during the Vesting Period, or if your Award vests early, until the date of such vesting. This payment will be made in cash or Shares, subject to deductions for Tax Liabilities, after your Award has vested, but in no event later than the US Taxpayer Payment Deadline (as defined in Rule 5.1 (as inserted by paragraph 7 of this Appendix 2)).”

 

 

 

 

9.The following shall be inserted as a new Rule 7.5:

 

“If an Award vests pursuant to this Rule 7, and the event described in Rule 7 also constitutes a “change in control event” under Section 409A of the US Internal Revenue Code of 1986, as it may be amended from time to time, and all regulations, interpretations and administrative guidance issued thereunder (the “Code”), then the Shares subject to it in respect of which it has vested will, subject to Rule 6, be transferred to you as soon as practicable following the vesting of an Award, but in no event later than the US Taxpayer Payment Deadline. If such event does not constitute a “change in control event” under Section 409A of the Code, then the Award will vest on the occurrence of such event described in Rule 7, but shall not be delivered to you until the earlier of the Vesting Date or the date on which your Award vests under Rule 3. For the avoidance of doubt, an Award shall only become payable upon the earlier of the Vesting Date or the date upon which your Award vests under Rule 3 or Rule 7.”

 

10.The following shall be inserted as a new Rule 13: “13. Section 409A of the Code.

 

13.1The compensation and benefits under the Plan are intended to comply with the requirements of Section 409A of the Code, and the Plan will be interpreted and administered in a manner consistent with that intent. The preceding provision, however, shall not be construed as a guarantee by AZ of any particular tax effect to you under an Award. Payment may only be accelerated or delayed if and to the extent that such accelerated or delayed payment is permitted under Section 409A of the Code.

 

13.2References to “end of Employment”, “cessation of Employment”, “termination of Employment” and similar terms used in the Plan mean, to the extent necessary to comply with Section 409A of the Code, the date that you first incur a “separation from service” within the meaning of Section 409A of the Code.

 

13.3Notwithstanding anything in the Plan to the contrary, if at the time of your separation from service with AZ you are a “specified employee” as defined in Section 409A of the Code, and any payment payable under the Plan as a result of such separation from service is required to be delayed by six months pursuant to Section 409A of the Code, then AZ will make such payment on the date that is six months following your separation from service with AZ. The amount of such payment will equal the sum of the payments that would have been paid to you during the six-month period immediately following your separation from service had the payment commenced as of such date and will not include interest.

 

 

 

 

13.4No Shares issued or payments made in respect of such an Award shall be funded with any assets set aside in a trust or other arrangement in violation of Section 409A(b)(1) of the Code. To the extent any trust is utilized in administration of the Plan, Awards granted to Eligible Employees who are US taxpayers need not be settled by Shares held in such a trust and such Awards do not form the basis for any claims or rights with respect to such a trust’s assets.

 

13.5In the first taxable year in which you become a US taxpayer by reason of becoming a resident alien for US federal income tax purposes, the Plan may be amended solely with respect to you such that the compensation and benefits under the Plan are compliant with or exempt from Section 409A of the Code. Such amendment must be effective not later than the end of the first year in which you become a resident alien and shall only be effective with respect to amounts that were not vested prior to the date that you became a resident alien. For any year after the first year in which you are classified as a resident alien, this clause shall not apply, provided that a year may again be treated as the first year in which you are classified as a resident alien if you are classified as a resident alien in that year and have not been classified as a resident alien for the three consecutive years immediately preceding that year. This clause will be interpreted consistent with the requirements of Section 409A of the Code, including Sections 1.409A-2(c) and 1.409A-3(h) of the US Treasury Regulations, as well as any subsequent guidance under Section 409A of the Code.

 

13.6Awards under the Plan that become vested while you are not subject to US federal income taxation but that are paid at a time when you subsequently have become subject to US federal income taxation are intended to be exempt from Section 409A of the Code. This clause will be interpreted consistent with the requirements of Section 409A of the Code, including Section 1.409A-1(b)(8)(ii) of the US Treasury Regulations, as well as any subsequent guidance under Section 409A of the Code.”

 

11.Rule 3.3 shall be deleted and replaced with the following:

 

“For the purposes of this Rule 3, if you are on an authorized leave of absence pursuant to an AZ policy or a legal entitlement, you will not end Employment until the earlier of the date on which you notify your employer of your intention not to return to work or the date on which you cease to have statutory or contractual rights to return to work.”

 

12.The following sentence shall be appended to the end of the existing Rule 8:

 

“Notwithstanding anything to the contrary, this Rule 8 shall not apply in any jurisdiction where its enforcement would be prohibited by applicable law.”

 

 

 

 

Appendix 3

 

France

 

1.This Appendix 3 governs the grant of Awards to French Participants

 

This Appendix 3 modifies the Rules of the Plan in respect of any Awards granted to participants who are French Participants.

 

This Appendix 3 has been drafted in order to allow Awards to benefit from the tax incentive as implemented under articles L.225-197-1 to L.225-197-3, L.22-10-59 and L.22-10-60 of the French Commercial Code, articles 80 quaterdecies of the French Tax Code and articles L.137-13 and L.242-1 of the French Social Security Code. The current provisions of this Appendix 3 include the regulations currently applicable in France. AZ may however have to amend the provisions of this Appendix 3 to take into account any new regulations that could arise in the future.

 

It is anticipated that Awards will be eligible for favourable tax and social security treatment in France. In the case where Awards would not benefit from the favourable tax and social security treatment in France, the French Participants are informed that they may have to bear the cost of any additional income tax arising as a result of the Award and, if requested by their employer, to reimburse their employer for any employee share of social security contributions, but not the employer social security contributions, (and any assimilated charges such as, but not limited to, the Contribution Sociale Généralisée).

 

The provisions of this Appendix 3 may be subsequently amended, if Awards appear not to be eligible for the favourable tax and social security treatment in France.

 

This Appendix 3 applies to Awards granted as from 1 January 2010 and, as amended, to Awards granted as from 3 February 2014 and, as further amended, to Awards granted as from 24 July 2017.

 

2.Adoption of French Qualified Part

 

The Plan and authority to adopt Appendix 3 was approved by the Board on 1 March 2010 and restated by RemCo on 22 October 2019, in compliance with the law under which AZ is incorporated. This Appendix 3 was adopted by RemCo on 1 March 2010 and restated on 22 October 2019.

 

In Rule 1 of the Plan, the following words shall be inserted:

 

“No Award shall be granted under Appendix 3: (i) more than seventy-six months after the date on which this Appendix 3 was restated by RemCo.”

 

 

 

 

3.The individual limit

 

The following limits shall apply in respect of Awards granted under the Rules of the Plan to French Participants:

 

(i)an Eligible Employee may not own more than 10% of the ordinary share capital of AZ at the date an Award is granted; and

 

(ii)an Eligible Employee may not own, as a result of the grant of an Award, more than 10% of the ordinary share capital of AZ.

 

4.Early vesting of an Award

 

Rules 3.1 and 3.2 of the Plan shall be deleted and replaced by the following:

 

"If a French Participant ceases to be in Employment before the Vesting Date:

 

(a)as an Eligible Leaver, his Award(s) will vest on the date the Employment ceases, pro-rated to take into account the period elapsed between the Date of Grant and the date of cessation of Employment relative to the Vesting Period, unless RemCo decides not to pro-rate or to pro-rate on some other basis; and

 

(b)other than as an Eligible Leaver, the Award will lapse on the date of cessation, unless RemCo, in its absolute discretion, decides otherwise, in which case RemCo has discretion to decide when and to what extent the Award may vest.

 

If a French Participant dies, the Shares will be transferred to the French Participant's personal representatives, provided that AZ has received written confirmation that the personal representatives are legally authorised to deal with the deceased French Participant's affairs, within 6 months after the death of the relevant French Participant. The terms under which the Shares would be transferred to the personal representatives and the ability for the personal representatives to dispose of the Shares will be determined according to the law and regulation applicable at the date of grant of the Award.

 

If an Award vests before the Vesting Date for any reason pursuant to the Plan, the French Participant may freely dispose of the Shares subject to it and in respect of which it has vested. However, in such circumstances, unless an Award vests following a French Participant ceasing Employment due to death, injury or disability corresponding to the second and third category as described under article L.341-4 of the French Social Security Code, the French Participant shall bear the cost of any additional income tax arising as a result of the early vesting of the Award and, if requested by their employer, will reimburse their employer for any employee share of social security contributions (and any assimilated charges such as, but not limited to, the Contribution Sociale Généralisée)."

 

5.Payments on account of dividends

 

Rule 5.4 of the Plan shall be deleted. No amounts shall be paid to French Participants or Directors in respect of dividends that would have been paid on the Shares that are subject to the Award during the Vesting Period.

 

 

 

 

6.Exchange of Awards

 

Rule 7.4 shall apply to French Participants. If there is an exchange of Awards for other awards upon a merger or a demerger realised in accordance with the applicable legislation during the Vesting Period, the preferential tax and social regime would continue to apply provided that the French Participant retains the shares received until the end of the Vesting Period.

 

In any other cases of an exchange of Awards, the French Participant shall bear the cost of any additional income tax arising as a result of the exchange of Awards and, if requested by their employer, will reimburse their employer for any employee share of social security contributions (and any assimilated charges such as, but not limited to, the Contribution Sociale Généralisée).

 

7.Limit on the number of shares which can be issued

 

If the Plan is amended at any time to permit Awards to be satisfied using newly issued Shares, no Award may be granted to French Participants or Directors if the number of Shares issued or capable of being issued pursuant to Awards granted under the Plan, when aggregated with the number of shares issued or capable of being issued pursuant to awards made or options granted under any other employees’ share scheme, would exceed 10 per cent of the ordinary issued share capital of AZ from time to time.

 

This 10 per cent limit does not include:

 

(i)any Shares that have not been effectively awarded at the end of the Vesting Period; or

 

(ii)any Shares that are no longer subject to a Vesting Period.

 

8.Sale restriction

 

After the Vesting Date, a French Participant or Director who is an employee of a Participating Company cannot transfer the Shares:

 

(i)Within the thirty (30) calendar days before the announcement of an interim financial report or a year-end report that AZ is required to make public.

 

(ii)At any time when the French Participant or Director is in possession of Privileged Information.

 

(iii)And in any case before the end of the Holding Period (if any).

 

 

 

 

9.Definitions

 

For the purpose of this Appendix 3, the following definitions will apply instead of the definitions in Appendix 1:

 

Director means any Président du Conseil d'Administration, Directeur Général, Directeur Général Délégué or Membre du Directoire of a Participating Company.

 

Eligible Employee means any person who at a Date of Grant is in Employment with a Participating Company.

 

Eligible Leaver means a French Participant who ceases to be in Employment as a result of death, injury or disability corresponding to the second and third category as described under article L.341-4 of the French Social Security Code, ill-health, redundancy (provided that, in the case of ill-health or redundancy, the Participant's employing company does not dispute that these are the reasons for the cessation), retirement with the agreement of his employing company, his employing company ceasing to be a member of the AZ Group or the business in which he is employed being transferred out of the AZ Group.

 

Employment means employment as an employee or Director of a Participating Company, though a Participating Company may decide on a case by case basis to include or exclude Directors from this Appendix 3.

 

French Participant means a participant in the Plan who is in Employment at a Participating Company and/or an Eligible Employee as defined in the main Rules of the Plan who is a French tax resident and/or is subject to French social security regulation.

 

Holding Period means in relation to an Award that vests less than two years after the Date of Grant, the period specified on the Date of Grant starting on the Vesting Date and ending at the earliest on the second anniversary of the Date of Grant. Notwithstanding the foregoing, unless RemCo has made a determination under Rule 5.5, if the last day of the Holding Period falls within a Closed Period, the last day of the Holding Period will be the first Dealing Day following the end of that Closed Period.

 

Participating Company means any French subsidiary of AZ within the meaning of section I of Article L225-197-2° of the French Commercial Code; provided, for the avoidance of doubt, that a company shall be a French subsidiary only if AZ holds, directly or indirectly, at least 10 per cent. of its share capital or voting rights.

 

Privileged Information means privileged information within the meaning of Article 7 of Regulation (EU) No. 596/2014 of the European Parliament and of the Council of 16 April 2014 on market abuse (Market Abuse Regulation) which has not been made public.

 

Vesting Date means in relation to an Award the date specified at the Date of Grant and determined by RemCo so that the Vesting Period shall be at least one year, save that if such date falls within a Closed Period, unless RemCo has made a determination under Rule 5.5, the Vesting Date will be the first Dealing Day following the end of that Closed Period.

 

 

 

 

Exhibit 23.1

 

 

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

 

We hereby consent to the incorporation by reference in this Registration Statement on Form S-8 of AstraZeneca PLC of our report dated 8 February 2024 relating to the financial statements and the effectiveness of internal control over financial reporting, which appears in AstraZeneca PLC’s Annual Report on Form 20-F for the year ended 31 December 2023.

 

/s/ PricewaterhouseCoopers LLP

London, United Kingdom
20 February 2024

 

PricewaterhouseCoopers LLP, 1 Embankment Place, London WC2N 6RH

T: +44 (0) 2075 835 000, F: +44 (0) 2072 124 652, www.pwc.co.uk

 

PricewaterhouseCoopers LLP is a limited liability partnership registered in England with registered number OC303525. The registered office of PricewaterhouseCoopers LLP is 1 Embankment Place, London WC2N 6RH.PricewaterhouseCoopers LLP is authorised and regulated by the Financial Conduct Authority for designated investment business and by the Solicitors Regulation Authority for regulated legal activities.

 

 

 

 

Exhibit 107

 

Calculation of Filing Fee Table

 

Form S-8 

(Form Type)

 

ASTRAZENECA PLC 

(Exact Name of Registrant as Specified in its Charter)

 

Table 1: Newly Registered and Carry Forward Securities

 

                             
               
Security
Type
 

Security

Class

Title

 

Fee

Calculation

Rule

 

Amount

Registered(1)

 

Proposed

Maximum

Offering

Price Per

Unit(2)

 

Maximum

Aggregate

Offering

Price

 

Fee

Rate

 

Amount of

Registration

Fee

 
Newly Registered Securities
               
Equity   Ordinary Shares, par value $0.25 each, represented by American Depositary Shares, to be awarded under the AstraZeneca PLC Global Restricted Stock Plan(3)   Rule 457(h)   20,000,000   $121.92   $2,438,400,000   0.0001476   $359,907.84
               
         
Total Offering Amounts       $2,438,400,000       $359,907.84
         
Total Fee Offsets              
         
Net Fee Due               $359,907.84

 

(1) Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the “Securities Act”), this Registration Statement covers any additional ordinary shares, par value $0.25 each, of AstraZeneca PLC (“Ordinary Shares”), represented by American Depositary Shares, each representing one half of one Ordinary Share (“ADSs”), that may be offered or sold under the terms of the AstraZeneca PLC Global Restricted Stock Plan by reason of any stock dividend, stock split, recapitalization or other similar transaction effected without the Registrant’s receipt of consideration which results in an increase in the number of the outstanding Ordinary Shares, represented by ADSs.

 

(2) Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(c) and Rule 457(h) under the Securities Act, based on the average of the high and low prices per ADS as reported on the Nasdaq Global Select Market on February 12, 2024, of $60.96, multiplied by two (the ratio of ADSs to Ordinary Shares).

 

(3) The Ordinary Shares shall be represented by ADSs. The ADSs issuable upon deposit of the Ordinary Shares registered hereby have been registered under separate registration statements on Form F-6 (File No. 333-258002 and File No. 333-236014).

 

 


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