Statement of Changes in Beneficial Ownership (4)

FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response... 0.5
	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person ^* ROSE WILLIAM	2. Issuer Name and Ticker or Trading Symbol REATA PHARMACEUTICALS INC [ RETA ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __ X __ Director __ X __ 10% Owner _____ Officer (give title below) __ X __ Other (specify below) Member of 10% owner group
(Last) (First) (Middle) 3963 MAPLE AVENUE, SUITE 200	3. Date of Earliest Transaction (MM/DD/YYYY) 11/13/2018
(Street) DALLAS, TX 75219 (City) (State) (Zip)	4. If Amendment, Date Original Filed (MM/DD/YYYY)	6. Individual or Joint/Group Filing (Check Applicable Line) ___ Form filed by One Reporting Person _ X _ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	3. Trans. Code (Instr. 8)		4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Class A Common Stock	11/13/2018		J ⁽¹⁾		811546	D	$0.00	0	I	By Puffin ⁽³⁾
Class A Common Stock	11/13/2018		J ⁽²⁾		811546	A	$0.00	879281	I	By trust ⁽⁴⁾
Class A Common Stock								11618	D ⁽⁵⁾
Class A Common Stock								7886	I	See Footnote ⁽⁶⁾
Class A Common Stock								20	I	By trust ⁽⁷⁾
Class A Common Stock								45	I	By trust ⁽⁸⁾
Class A Common Stock								13517	D ⁽⁹⁾
Class A Common Stock								29	I	See Footnote ⁽¹⁰⁾
Class A Common Stock								180909	I	By Montrose ⁽¹¹⁾

*Table II - Derivative Securities Beneficially Owned ( e.g.* , puts, calls, warrants, options, convertible securities)**
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	4. Trans. Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)			11. Nature of Indirect Beneficial Ownership (Instr. 4)

Explanation of Responses:
(1)	Pro rata distribution of 811, 546 shares of Class A common stock from Puffin Partners, L.P. ("Puffin"), to the Evelyn Potter Rose Survivor's Trust (the "Survivor's Trust"), its limited partner and the beneficial owner of such shares.
(2)	Receipt of 811,546 shares of Class A common stock beneficially owned by the Survivor's Trust as a pro rata distribution from Puffin.
(3)	These shares were owned directly by Puffin. Each of (a) William E. Rose, a director of the issuer, and (b) Charles E. Gale serve as co-managers of the general partner of Puffin. Mr. Rose and Mr. Gale disclaim pecuniary interest in the shares held by Puffin.
(4)	These shares are owned directly by the Survivor's Trust, a ten percent owner of the issuer, for which Charles E. Gale and Evelyn P. Rose serve as co-trustees.
(5)	These shares are owned directly by William E. Rose, a director of the issuer.
(6)	These shares are owned directly by Evelyn P. Rose Fidelity Rollover IRA and indirectly by Evelyn P. Rose.
(7)	These shares are owned indirectly by William E. Rose, a director of the issuer, as co-trustee of the Charles Henry Rose 2001 Trust.
(8)	These shares are owned indirectly by William E. Rose, a director of the issuer, as co-trustee of the John William Rose 2002 Trust.
(9)	These shares are owned directly by Charles E. Gale.
(10)	These shares are owned directly by the Charles E. Gale Fidelity Rollover IRA and indirectly by Charles E. Gale.
(11)	These shares are owned directly by Montrose Investments I, L.P. ("Montrose"), and indirectly by William E. Rose, a director of the issuer, as sole shareholder and sole manager of the general partner of Montrose.

Remarks:
The reporting persons may be deemed to be members of a group with other affiliated entities that collectively are 10% owners, which group includes William E. Rose, Evelyn P. Rose, Evelyn P. Rose Fidelity Rollover IRA, Evelyn Potter Rose Survivor's Trust, Charles Henry Rose 2001 Trust, John William Rose 2002 Trust, Charles E. Gale, Charles E. Gale Fidelity Rollover IRA, Puffin Partners, L.P., Puffin GP, LLC, Montrose Investments I, L.P. and Montrose Investments GP, LLC (collectively, the "Affiliated Rose Reporting Persons"). As a result of the transaction reported in this Form 4, Puffin Partners, L.P. and Puffin GP, LLC are exiting the group.

The reporting persons disclaim the existence of a group and disclaim beneficial ownership of any securities held by the other Affiliated Rose Reporting Persons, except to the extent of their respective pecuniary interests therein.

Form 1 of 2.

Reporting Owners
Reporting Owner Name / Address	Relationships
Reporting Owner Name / Address	Director	10% Owner	Officer	Other
ROSE WILLIAM 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219	X	X		Member of 10% owner group
Puffin Partners, L.P. 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219				Member of 10% owner group
Puffin GP, LLC 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219				Member of 10% owner group
Montrose Investments I, L.P. 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219				Member of 10% owner group
Montrose Investments GP, LLC 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219				Member of 10% owner group
Gale Charles E. 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219		X		Member of 10% owner group
Charles E. Gale Fidelity Rollover IRA 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219				Member of 10% owner group
Rose Evelyn P. 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219		X		Member of 10% owner group
Evelyn P. Rose Fidelity Rollover IRA 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219				Member of 10% owner group
Evelyn Potter Rose Survivor's Trust 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219		X		Member of 10% owner group

Signatures
/s/ Charles E. Gale, Attorney-In-Fact for William E. Rose		11/14/2018
^** Signature of Reporting Person		Date
/s/ Charles E. Gale, as Co-Manager of Puffin GP, LLC, the General Partner of Puffin Partners, L.P		11/14/2018
^** Signature of Reporting Person		Date
/s/ Charles E. Gale, Co-Manager of Puffin GP, LLC		11/14/2018
^** Signature of Reporting Person		Date
/s/ Charles E. Gale, Attorney-In-Fact for Montrose Investments I, L.P.		11/14/2018
^** Signature of Reporting Person		Date
/s/ Charles E. Gale, Attorney-In-Fact for Montrose Investments GP, LLC		11/14/2018
^** Signature of Reporting Person		Date
/s/ Charles E. Gale		11/14/2018
^** Signature of Reporting Person		Date
/s/ Charles E. Gale, Authorized Signatory for the Charles E. Gale Fidelity Rollover IRA		11/14/2018
^** Signature of Reporting Person		Date
/s/ Charles E. Gale, Attorney-In Fact for Evelyn P. Rose		11/14/2018
^** Signature of Reporting Person		Date
/s/ Charles E. Gale, Authorized Signatory for the Evelyn P. Rose Fidelity Rollover IRA		11/14/2018
^** Signature of Reporting Person		Date
/s/ Charles E. Gale, Trustee and Attorney-In-Fact for the Evelyn Potter Rose Survivor's Trust		11/14/2018
^** Signature of Reporting Person		Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:	File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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