RNS No 5174q
TEPNEL LIFE SCIENCES PLC
3rd December 1998


TEPNEL LIFE SCIENCES PLC ("the company")

Further to the announcement of Directors' Dealings on 30 September 1998, the
Company wishes to announce that the interests, following market purchases on
29 September 1998, for Mr. M.D. Billingham and Mr. P. Raymond, Directors of
the Company, should have read as follows:

Director            Total Holding                       % ISC
                    following purchase                  following purchase

M.D. Billingham     23,900                              0.05% 

P. Raymond          20,700                              0.04%

END

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