RNS Number:2309V
Tepnel Life Sciences PLC
10 February 2004


                    TEPNEL LIFE SCIENCES PLC ("the Company")

                                10 February 2004

                               HOLDING IN COMPANY

The Company received notification on 10 February 2004 from Framlington
Investment Management Limited, that it is interested in 7,369,348 ordinary
shares of 1p each in the Company ("Shares"), representing approximately 5.51% of
the Company's issued share capital.

These shares are registered as follows:

HSBC Global Custody Nominee (UK) Limited a/c 811664



                                      END

For Further Information:

Tepnel Life Sciences plc
Ben Matzilevich, Chief Executive Officer
Gron Ffoulkes-Davies, Finance Director
0161 946 2200


De Facto Communications
Yvonne Alexander
020 7496 3300

Notes to Editors

About Tepnel Life Sciences PLC

Tepnel Life Sciences is a UK-based international life sciences instrumentation
and servicescompany with a 'tri-polar' strategy focused on providing the
biomedical industry with high-throughput automated DNA purification systems,
manual DNA purification kits and reagents, as well as scientific services for
nucleic acid purification, drug analysis, genotyping and genetically modified
foods. Tepnel Life Sciences was founded in 1992 to exploit DNA technology
generated at UMIST (University of Manchester Institute of Science and
Technology) and is quoted on the AIM segment of the London Stock Exchange (AIM:
TED). More information on Tepnel can be found at www.tepnel.com.




                      This information is provided by RNS
            The company news service from the London Stock Exchange

END
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