RNS Number:8690Y
Tepnel Life Sciences PLC
19 July 2002

TEPNEL LIFE SCIENCES PLC ("the Company")

19 July 2002

HOLDING IN COMPANY

The Company today received notification from Framlington Investment Management
Limited that they are interested in 12,475,000 ordinary shares of 1p each in the
Company ("Shares") representing approximately 12.82% of the Company's issued
shares.

These Shares are registered as follows:

HSBC Nominees Ltd a/c 811664                 10,800,000

HSBC Nominees Ltd a/c 811524                   1,275,000

HSBC Nominees Ltd a/c 896177                      400,000

The previous notified holding announced on 13 February 2002 was 12,675,000
Shares, representing 13.22% of the then, number of ordinary shares issued.

END




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