RNS Number:1097W
Tepnel Life Sciences PLC
04 May 2007



              Tepnel Life Sciences plc ("Tepnel" or the "Company")

                              Directors' holdings

In conformity with the provisions of the EU Transparency Directive, the Company
was informed on 3 May 2007 that Ben Matzilevich, the Company's Chief Executive
Officer, purchased on 3 May 2007 112,000 ordinary shares, representing
approximately 0.05 per cent. of the ordinary issued share capital of the
Company, at 8.875p per share. As a result of this purchase, Mr Matzilevich is
now interested in 5,956,783 ordinary shares representing approximately 2.59 per
cent. in the issued share capital of Tepnel.

In conformity with the provisions of the EU Transparency Directive, the Company
was informed on 3 May 2007 that Alec Craig, the Company's Non-Executive
Chairman, purchased on 3 May 2007 17,837 ordinary shares, representing
approximately 0.01 per cent. of the ordinary issued share capital of the
Company, at 8.875p per share. As a result of this purchase, Mr Craig is now
interested in 1,000,000 ordinary shares representing approximately 0.43 per
cent. in the issued share capital of Tepnel.




                      This information is provided by RNS
            The company news service from the London Stock Exchange

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