RNS Number:3300S
Tepnel Life Sciences PLC
11 October 2000


                     TEPNEL LIFE SCIENCES  PLC ("TEPNEL")
                                www.tepnel.com

Tepnel's  business  is  the  commercialisation of enabling  DNA  technologies,
primarily for the use in life science research, clinical and food testing  and
the  development of automated systems for these processes.  In support of  our
core  business,  we  are  expanding  our revenue  generating  operations  both
organically and through synergistic acquisitions.
                                       
                                  Highlights

*    Plasmid DNA purification instrument close to commercialisation;
*    Successful integration of Nucleon businesses purchased during the year;
*    Launch of the first, and only, rapid gluten test available to both
     industrial and home users;
*    Strategy of developing and selling complementary services used for DNA
     analysis continues to reinforce profit generation;
*    Six fold increase in group turnover to #1.13 million  (1999: #0.17
      million);
*    Operating losses have fallen 23 per cent to #1.9 million (1999: #2.6
     million);
*    Solid cash position through December 2001, leaving the Company in strong
     financial position and with important flexibility during key period of
     commercial development.

Commenting on the results, Peter Raymond, Chairman of Tepnel Life Sciences,
said:

" We are very pleased with Tepnel's progress in 2000.  The Company has made
positive, steady progress.  Sales have grown, losses and expenses have been
reduced and our portfolio of products and services continues to expand.  With
shareholder funds under prudent management and our DNA automation instrument
close to commercialisation, Tepnel is poised for significant growth."

Enquiries:

                  Hudson Sandler                020-7796-4133
                  Piers Hooper
                  Jessica Rouleau
          
                                                                    
                             CHAIRMAN'S STATEMENT
                     Tepnel Life Sciences ("the Company")
                          Preliminary Results -  2000
                                       
Introduction

Once again, I am pleased to be able to report that Tepnel has made positive,
steady progress for the year ending June 30, 2000.  Sales have grown, losses
and expenses have been reduced and the portfolio of products and services
continues to expand.  Our strategy of developing and selling complementary
products and services, used for DNA analysis, has continued to reinforce the
Company's ability to boost profit generation and shareholder value.   During
the last 10 months, Tepnel entered into a #2.2 million convertible secured
loan facility and placed 2,090,909 new ordinary shares, raising #2.3 million.
To date, the Company has not needed to draw down on the loan facility, leaving
it in a strong financial position and providing important flexibility during
this key period of commercial  development.  With shareholder funds under
prudent management and our first DNA purification instrument close to
commercialisation, Tepnel is poised for a significant leap forward.

Financial Results

Turnover has reached #1.13 million, a six fold increase over last year's sales
of #0.17 million. Operating losses have fallen from #2.6 million in 1999 to
#2.0 million this year, a decrease of 23 per cent.  Working capital is
sufficient to achieve our current objectives and together with the #2.2m loan
facility, negotiated in December 1999, will fund the Company through to
December 2001. The basic loss per share for the year ending 30 June 2000 has
decreased from 4.9p per share in 1999, to 3.9p per share.

Strategies

We continue to focus on three business areas: the development and
commercialisation of automated DNA systems, the provision of contract services
and the sale of manual reagents/development of intellectual property.
Automation is clearly the principal driver of our business going forward.
However, the exploitation of Tepnel's intellectual property and the sale of
reagents provide important additional sources of growth and revenue.  Our
integrated strategy of providing complete solutions, ranging from laboratory
services and kits through to automated instrumentation, enables us to provide
a wider selection of products and services to our customers, on a more cost-
effective basis.  The expertise we have developed across the range of DNA
products and services gives us technical credibility and a strong basis for
growth in all the group's activities. This growth will continue in part due to
the success of the Human Genome project.


A.  Automation

Current Projects: The markets for which we are developing our automated DNA
purification machines are growing strongly.  It is estimated that the global
market for clinical DNA diagnostics is currently in the region of USD900
million and growing at about 20 per cent a year.   The Life Science research
market is currently in the order of USD300 million and is growing almost as
fast as the clinical market, at about 15 per cent a year.   There is huge
potential in these markets and given the advantages offered by Tepnel's
automated systems, this part of the business has excellent prospects going
forward.

To realise the potential of our systems it is essential that we select the
right partner(s) who are committed to developing sales in the target market.
During the last year we have been working closely with a number of potential
partners regarding the system for plasmid purification and have developed a
short list of global companies who meet our criteria. This interaction with
the leading companies in the Life Sciences market ensures that our system will
meet the needs of target users.

Our most advanced prototype system for plasmid purification and an early
prototype for purifying genomic DNA from whole blood were exhibited at the
American Association of Clinical Chemistry, in July 2000 in the US.   The
technical data we presented on the performance of DNA purified on both systems
in downstream applications generated a great deal of interest from potential
commercial partners, global distributors and end-users.

We are currently pursuing distinct commercialisation strategies for the two
automated systems. Given the differences in the target markets, this approach
will ensure that we realise the full value of the technologies we have
developed.  For the plasmid system, which targets the life science research
market, we are talking to distribution partners, who have access to the
relevant market segments. Manual plasmid purification is well established and
customer requirements for our automated system will not vary widely. The
clinical/Pharma market, for which we are developing the blood system, is, in
contrast, a market with a number of sub-segments, many of which present a
significant opportunity for our technology.  In order to serve the range of
clinical/pharma customer needs, we will select co-development partners and
discussions with potential companies are underway.  A co-developer with an in
depth knowledge of the market's sub-segments will be able to contribute to the
final system specifications required by customers.

In addition to on-going work on the commercialisation of the automated
systems, we have been working with our partners to enhance the design of the
plasmid system.   We have added a shaker, bringing one more level of
automation to the system.  Tepnel's fully automated system will process 96
samples in less than two hours, with no human intervention required at any
point during the process.    In addition to the obvious advantages provided by
its processing ability, other competitive advantages of our system include;
the full integration of instrumentation, consumables and software; the ability
to simply process any number of samples between 1 and 96; and the opportunity
for customers to order from a single supplier, including the provision of any
required technical and sales support.  Finally, the size and weight of the
unit will be significantly less than competitors', making it attractive to
researchers for whom bench space and flexibility is always an issue. In
addition, because of the manual touch screen approach a separate PC is not
required further reducing the cost and space requirements.

B.  Services:
This year we have also emphasised the development of a DNA service capability
as a key aspect of our strategy to build our reputation and technical
credibility with larger customers.  This approach will, in turn, expand the
potential customer base for our higher margin automated products.   The DNA
purification service, launched in January 2000, is steadily building its
reputation through the processing of customer's samples and responding to
their specific requirements. Although out-sourcing of this work is not yet
widespread, excellent market opportunities exist to grow this part of the
business.

In addition a service to detect the presence of genetically modified organisms
in food was launched at the end of the year.

C.  Manual Reagents and IP Development:
i)  Nucleon Kits:  Following the acquisition of the Nucleon Business in March
2000 manufacturing, sales and marketing have been successfully transferred and
integrated into the Manchester site.   A sales operation has also been
established in the UK, providing Tepnel with direct access to Nucleic Acid
Purification customers. International sales are provided by Amersham Pharmacia
Biotech.

ii)  Food Testing:  The integration of our food testing businesses, purchased
last year, has been very successful.  We continue to innovate and expand the
products and services we offer our customers.  In this regard, we recently
launched the first, and only, rapid gluten test available to both industrial
and home users, for use by Coeliac disease suffers (A disease resulting from
an intolerance to wheat products).  In addition, we expect to add further food
identification tests to our portfolio over the next year.

iii)  Development of Intellectual Property:  The value of our intellectual
property portfolio continues to increase as we are granted patents in the US
and Europe.  During the year, the European patent for DARAS detection
technology was granted and other patents relating to our automation projects
were filed.

Acquisitions

The group has made two acquisitions during the year: magnetic bead technology
from Nuclyx and the Nucleon Kit Business/Analytical Contract Services from
Genesys Biotech. Our acquisition strategy is focused on companies that provide
us with access to enabling technologies (e.g. magnetic beads) or to customers
and ready channels to market.   As a result of these acquisitions, we believe
we will be able to leverage our enlarged customer base, offering automation,
contract services and manual reagents. All of these acquisitions have been
successfully integrated and should make profit contributions in 2001.

We continue to consider acquisitions that fit these criteria and provide us
with these important synergies.

5 Future Prospects
Tepnel continues to make good progress towards its financial and commercial
goals.   Our strategy, which builds on the synergies between our products and
services, leaves us in an excellent position to take advantage of the
significant growth in the markets we serve.  Tepnel aims to be a major player
in automated systems for DNA analysis supported by contract services and
manual reagents for the life sciences research, clinical/Pharma and food
testing markets.





Consolidated profit and loss account              
For the year ended 30 June 2000

                                       2000              1999
                               #'000      #'000     #'000       #'000
                                                  
Turnover                                  1,130                   174
Cost of Sales                              (646)                  (59)
                                          ------               ------
                                                          
Gross Profit                                484                   115
                                                  
Research and Development      (1,103)             (1,553)  

Sales and Marketing             (570)               (531)  
Administrative Expenses         (828)               (667)  
                                                          
Total administrative expenses             (2,501)              (2,751)
                                          -------              -------
Operating Loss                            (2,017)              (2,636)
                                                          
Interest Payable                              (2)                   -
Interest Receivable                           74                  260

                                          -------              -------        
Loss on ordinary activities
before taxation                           (1,945)              (2,376)
                                                          
Taxation                                       -                    -
                                                          
Loss for the financial year               (1,945)              (2,376)
                                                       
                                                          
Basic loss per share                         3.9p                 4.9p
                                                          
Fully diluted loss per share                 3.9p                 4.9p



The Group's activities for the year relate to continuing operations and
include all recognised gains and losses.


Consolidated Balance Sheet                              
At 30 June 2000                                    
                                    2000                    1999
                             #'000       #'000         #'000     #'000
Fixed Assets                                       
Intangible assets                        1,622                   1,091
Tangible assets                            545                     350
                                         -----                   -----
                                         2,167                   1,441
Current Assets                                              
Stocks                         356                       451          
Debtors and prepayments        492                       279          
Investments                     20                        25          
Cash at bank and in hand     2,037                     2,064          
                             -----                     -----
                             2,905                     2,819          
Creditors : amounts                                         
falling                  
due within one year            674                       531
                             -----                     -----
                                                            
Net current assets                       2,231                   2,288
                                         -----                   -----
                                                            
Total assets less                                           
current liabilities                      4,398                   3,729
                                         -----                   -----
                                                            
Capital and reserves                                        
Called up share capital                    520                     488
Share premium account                   18,572                  15,990
Profit and loss account                (14,694)                (12,749)
                                        ------                  ------
                                                            
Shareholders funds                       4,398                   3,729


All items under capital and reserves are equity


Consolidated Cash Flow Statement               
For the year ended 30 June 2000                   2000            1999
                                                 #'000           #'000
Reconciliation of operating loss to                    
net cash flow from operating activities
Operating Loss                                  (2,017)         (2,636)
Depreciation                                       196             159
Amortisation                                        33               1
Provision against current asset investments          5               -
Decrease in stocks                                 138             186
(Increase) / decrease in debtors                  (213)             86
Increase / (decrease) in creditors                 129             (64)
Profit on disposal of fixed assets                  (5)             (2)
                                                ------          -------
Net cash outflow from operating       
activities                                      (1,734)         (2,270)
                                                -------         -------       
                                       
Consolidated cash flow statement                       
Net cash outflow from operating
activities                                      (1,734)         (2,270)
Returns on investments                              72             260
Acquisitions                                      (431)         (1,052)
Investing activities                              (292)             33
Net cash outflow before financing               (2,385)         (3,029)
Management of liquid resources                     396           2,999
Financing                                        2,358              10
                                                 -----           -----
Increase / (decrease) in cash                      369             (20)
                                                 -----           -----
                                                       
Reconciliation of net cash flow to                     
movements in net funds
Increase / (decrease) in cash                      369             (20)
Cash inflow from short term deposits              (396)         (2,999)
Cash outflow from decrease in lease financing        6               -
                                                 ------         -------
Change in net funds resulting from cash flow       (21)         (3,019)
New finance leases                                 (20)              -
Net funds at the beginning of year               2,064           5,083
                                                 ------         ------
Net funds at the end of year                     2,023           2,064
                                                 ------         ------


Notes:
1.   Nature of Preliminary Announcement
     The financial information supporting the preliminary announcement
     relating to Tepnel Life Sciences PLC does not constitute statutory
     accounts as defined by Section 240 of the Companies Act 1985. The
     abridged comparative financial information for the year to 30 June 1999
     has been based on the statutory accounts of Tepnel Life Sciences PLC for
     the year to 30 June 1999. These accounts have been reported on by the
     Company's auditors and delivered to the Registrar of Companies. The
     report of the auditors was unqualified and did not contain a statement
     under section 237(2) or (3) of the Companies Act 1985.
     The preliminary financial statements have been prepared on the basis of
     the accounting policies set out in the Group's 1999 statutory accounts.
     The auditors have not yet reported on the accounts for the year ended 30
     June 2000. The statutory accounts for the year will be delivered to the
     Registrar of Companies following the Company's Annual General Meeting.
2.   The Directors do not recommend the payment of a dividend.
3.   The turnover for the year to 30 June 2000 includes #119,231 relating to
     acquisitions.   Tepnel BioSystems Limited which acquired BioKits food
     diagnostics and laboratory services businesses in the previous financial 
     year contributed #889,837 to turnover.
     All business divisions contribute to central administrative expenses and
     it is not considered practicable to analyse operating profits or losses
     by business segment.
4.   The basic loss per share has been calculated on the average number of
     shares in issue during
     the year, namely 49,943,395 (1999 - 48,794,379) and losses of #1,945,000
     (1999 - #2,376,000).
     In both years the diluted loss per share is the same as the basic loss
     per share.
5.   Acquisitions
     On 10 August 1999 Tepnel Life Sciences PLC acquired the assets, goodwill
     and know-how related to novel magnetic bead technology developed by
     Nuclyx Ltd for a total consideration of #350,000. #100,000 of this sum
     was payable immediately and the balance satisfied by granting a #250,000
     secured convertible loan note. The loan note was converted into ordinary
     shares in December 1999 at an exercise price of 25p.
     On 18 March 2000 the Company acquired, from Genesys Biotech Ltd, the
     trade, assets and goodwill of two businesses specialising in the DNA
     purification market - Nucleon BioSciences and Nucleon Analytical. The
     total consideration was #300,000, paid in cash, plus a maximum of 300,000
     share options, exercisable at a price of 100p, conditional on meeting
     agreed sales targets.
6.   On 8 December 1999 the Company entered into a 2-year term convertible
     loan facility of #2.2million provided by BF Finance Ltd. The facility    
     will be secured on the Company's intellectual property rights. The       
     facility will be repayable in whole or in part by the Company at any time
     prior to 31 December 2001. If the loan has not been repaid prior to 31   
     December 2001, BF Finance Ltd will be entitled to demand repayment of the
     facility in whole or in part and/or to convert the outstanding amount of 
     the facility into Ordinary Shares at a price equal to the greater of 100p
     per share and the average price on the four Fridays preceding the date of
     conversion less 15%. Interest will be payable at the rate of 12% per     
     annum on the amounts drawn down.  In consideration for the provision of  
     the facility, the Company agreed to grant share options enabling BF      
     Finance Ltd to subscribe for 2.2 million Ordinary shares. 1.1million of  
     these options are exercisable at a price of 100p per share
     and the remaining 1.1 million at a price of 48p.
     
7.   On 16 March 2000 2,090,909 Ordinary Shares of 1p each were placed at a
     price of 110p to raise #2,300,000 to provide additional working capital.
     



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