RNS Number:9048O
Tepnel Life Sciences PLC
14 July 2005


              Tepnel Life Sciences PLC ('Tepnel' or 'the Company')

             Rule 2.10 Announcement - Relevant Securities in Issue

In accordance with Rule 2.10 of the City Code on Takeovers and Mergers, Tepnel
announces that its current issued share capital comprises 212,927,315 ordinary
shares of 1p each. In additional, the Company issued 419,100 warrants,
exercisable at 6.98p, within five years of the date of issue (being 2 November
2004) and a further 74,477,000 warrants, exercisable at 6.98p, within seven
years of the date of issue (being 2 November 2004).

The following options are also outstanding:

Date of              Number of   Period of Options                   Price per
grant                   Shares                                           share

29 Sept.1998           129,000   29 Sept. 2002 - 28 Sept.2008             20.0p
8 Dec. 1999          1,050,000   8 Dec. 1999 - 31 Dec. 2004               48.0p
8 Dec. 1999          1,050,000   8 Dec.1999 - 31 Dec. 2004               100.0p
21 Dec. 1999            45,000   21 Dec. 2002 - 21 Dec. 2009              62.5p
18 March               300,000   18 March 2001 - 18 March                100.0p
2000                             2005
22 Nov. 2000            35,000   22 Nov. 2003 - 21 Nov. 2010              83.5p
19 March             5,000,000   19 March 2003 - 18 March                 50.0p
2001                             2011
1 May 2001               5,000   1 May 2004 - 30 April 2011               30.0p
9 Nov. 2001            206,000   9 Nov. 2004 - 8 Nov. 2011                22.0p
20 Dec. 2001           250,000   20 Dec. 2003 - 19 Dec. 2011              19.0p
2 May 2002             837,700   1 June 2005 - 1 Dec. 2005                10.0p
16 April             7,335,000   17 April 2005 - 17 April                6.125p
2003                             2015
13 May 2003            215,000   14 May 2005 - 14 May 2015                 8.0p

The International Securities Identification Number for Tepnel's ordinary shares
is GB0008841859.



                      This information is provided by RNS
            The company news service from the London Stock Exchange
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