RNS Number:1720C
Tepnel Life Sciences PLC
8 December 1999


                     TEPNEL LIFE SCIENCES
                        ("the Company")
                               
     #2.2m convertible secured loan facility and issue of
     warrants to subscribe for up to 2.2m Ordinary Shares
                               
                               
   
   The  Company  announces  that,  subject  to  shareholder
   approval,  it  has arranged a convertible  secured  loan
   facility   of   #2.2m  to  provide  additional   working
   capital.
   
   Background
   
   The  Company  has continued to develop the food  testing
   business  which  was acquired in June  1999,  integrated
   into  Tepnel BioSystems, and which has traded profitably
   since  then.  The Company has also been progressing  its
   DNA  technologies and in particular the  development  of
   its  automated DNA purification machine for the research
   and  clinical  markets.  Following a positive  reception
   for  its  prototype  96  sample  automated  purification
   machine  for  the  clinical  research  market   at   the
   American  Association  of Clinical Chemists'  Exhibition
   in  July  1999, the Company is currently in early  stage
   discussions  with  a  number of international  companies
   regarding  distribution of the equipment.   The  Company
   also  has plans to develop equipment which would  enable
   DNA to be extracted from whole blood.
   
   Cash  at  30  June  1999 was #2.1m and the  Company  has
   continued  to make overall losses since then as  it  has
   continued  the  development of its  DNA  products.   The
   directors  believe it is in shareholders'  interests  to
   continue  its  research  and development  and  marketing
   expenditure  at their current levels, but this  strategy
   would  mean  that the Company would not have  sufficient
   funds  to  continue  beyond 30 June 2000.   The  Company
   hopes  to conclude at least one distribution arrangement
   for its purification equipment by the end of the end  of
   the  Company's current financial year, which would start
   the  commercialisation  of  the  products  and  lead  to
   revenues  from them being generated in the  second  half
   of 2000.
   
   Whilst  the  Company  has considered various  additional
   financing  options  prior to concluding  such  marketing
   arrangements,   the   directors   believe    that    the
   availability  of  the facility will  provide  additional
   financial   strength  in  negotiations  with   potential
   distribution  partners  as  well  as  securing   working
   capital  which the directors anticipate will last  until
   at  least  30  June 2001 if the facility is fully  drawn
   down.   The Company has therefore conditionally  entered
   into  the  agreement with BF Finance Limited ("BFF"),  a
   special  purpose  company, for  the  provision  of  this
   facility and the grant of the warrants.
   
   The Facility
                               
   The  facility  from BFF will be available for  draw-down
   at  the Company's discretion over a period of two  years
   from  7 January 2000 in minimum tranches of #25,000  and
   a  maximum of #200,000 per calendar month.  The facility
   will  be  secured  by an assignment of the  intellectual
   property rights of the Company.
   
   The  facility will be repayable either in  whole  or  in
   part  by  the  Company at any time prior to 31  December
   2001.   If  the  loan has not been repaid  prior  to  31
   December  2001, BFF will be entitled to demand repayment
   of  the  facility in whole or in part and/or to  convert
   the   amount  of  the  facility  then  outstanding  into
   Ordinary  Shares at a price equal to the greater  of  #1
   per  Ordinary  Share and the average mid-market  closing
   price  of  the  Ordinary  Shares  on  the  four  Fridays
   immediately  preceding the date of conversion  less  15%
   of  such average price.  Interest will be payable at the
   rate  of  12% per annum on the amounts drawn down.   The
   facility  will  become  immediately  repayable  on   the
   occurrence  of certain events, including the acquisition
   or merger of Tepnel and certain fund raising events.
   
   In  consideration for the provision of the facility, the
   Company  has  agreed  to grant  warrants  to  BFF.   The
   warrants  enable  the  holders  to  subscribe  for  2.2m
   Ordinary Shares, of which 1.1m are at a price of #1  per
   Ordinary  Share  and  1.1m are at a  price  of  48p  per
   Ordinary  Share (being the price of the Ordinary  Shares
   on  the  date  on  which the proposals  were  agreed  in
   principle).   The warrants, which will be unlisted,  are
   exercisable  at  any  time up to  31  December  2004  in
   minimum  tranches  of 25,000 Ordinary Shares.   Assuming
   the  exercise of all the warrants and the conversion  of
   the  whole of the facility, the maximum equity  dilution
   would  be  9.017% of the existing equity.  The  Ordinary
   Shares  to  be issued as a result of both the conversion
   of  the  facility and the warrants will rank pari  passu
   with  the  existing Ordinary Shares.   Exercise  of  the
   warrants would raise #1.480m for the Company.
   
   The Extraordinary General Meeting
   
   Resolutions   will   be  put  to  shareholders   at   an
   Extraordinary General Meeting to be held  on  7  January
   2000 at 30 Lombard Street, London, EC3V 9EN at 10am  for
   the  purpose  of  obtaining shareholder consent  to  the
   facility.
   
   Mr Peter Raymond, Chairman, commented:
   
   "The  facility  provides us with the additional  working
   capital   we  require  to  continue  focusing   on   the
   commercialisation  of  our  nucleic  acid   purification
   technology  with  only  modest  potential  dilution   of
   shareholders' interests.  Most importantly, it gives  us
   time to select the best commercial partner for both  the
   short and long term future of Tepnel."
   
                               
                                 
   For further information, please contact:
   
   Tepnel Life Sciences PLC
   Tel: 0161 445 9457
   Peter Raymond, Chairman
   Mike Billingham, Commercial Director
   Jeremy Lee, Finance Director
   
   Rawlings Financial PR Limited
   Tel: 01756 770 376
   Catriona Valentine
   
   
   Notes to Editors
   
   This  facility provides Tepnel with stability in the  final
   development   stages  of  its  automated  DNA  purification
   system.    It  also  gives  the  Company  enough  time   to
   establish  a  strong  working relationship  with  potential
   partner(s),  who  have the capability to commercialise  the
   technology for sale directly into the research market.
   
   Following   a   successful  feasibility   programme,   this
   facility  will allow the Company to initiate a  development
   programme  targeting DNA purification from  blood  for  the
   clinical market.  This development programme would  ideally
   be undertaken with a partner company.
   
   Furthermore,  the  facility  will  enable  the  Company  to
   continue  the development of  its strategy for  introducing
   DNA testing into the food industry.
   
   Additional information is available from the Company.
   
   

END
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