RNS No 6017e
TEPNEL LIFE SCIENCES PLC
6 October 1999

                                       
                              PRELIMINARY RESULTS
                                       
Tepnel  Life  Sciences  PLC  ("Tepnel" or the  "Company"),  the  developer  of
proprietary  DNA  diagnostic systems for the life science  research,  clinical
diagnostics, food and environmental testing markets, announces its preliminary
results for the year ended 30 June 1999.

Financial Key Points:

* Loss in line with budget at #2.376 million (1998: #2.587 million)

* Loss per share down at 4.9p (1998: 5.3p)

* The cash balance at 30 June 1999 was #2.064 million (1998: #5.083 million)


Key Points:

* Prototype 96 column automated DNA purification system well received by
  potential commercial partners

* Acquisition of Biokits and Laboratory Services in June 1999, generating
  income and profit

* Strategic purchase of magnetic bead technology in August 1999 for use in the
  DNA purification system

* DTI SMART award received for feasibility study on signal amplification
  technology

* DARAS and SPA patents granted in the USA


Chairman,  Peter Raymond, said:  "During 1999, all of Tepnel's resources  were
focused  on business opportunities with income generating potential and  I  am
pleased to report that the Company has made real progress in building  a  base
for future profits generation.

"A  prototype  96  column  automated DNA purification instrument  was  rapidly
developed from our existing instrumentation platform.  This prototype was well
received  by  an international audience at a major scientific meeting  in  New
Orleans  in  July  1999  and has since generated a great  deal  of  commercial
interest.

"Our  newly  formed  subsidiary,  Tepnel  BioSystems  Limited  purchased   two
businesses  in  June 1999 - BioKits and Laboratory Services.   These strategic
acquisitions   provide   us  with   a  profitable  vehicle  to deliver our DNA
technologies to the food testing and related industries.

"We have continued to keep tight control of our costs and cash reserves at the
year-end were #2.064 million (1998: #5.083 million). Net cash  outflow for the
year  of  #3  million  included  the  #1 million consideration  paid  for  the
BioKits and  Laboratory Services businesses.

"Following  the  presentation  of  our prototype  96  column  DNA purification
instrument, we have  entered  into  discussions  with a  number  of  potential
partners.    In  addition,  Tepnel's  purification system is based on magnetic
bead technology  and,  following  a  significant  period  of joint development
work, we  acquired  this technology in August 1999, ensuring that we now fully
control the reagent stream.

"Tepnel  BioSystems has successfully merged the  two  acquired businesses  and
is  already  selling  a  range  of  DNA-based  kits  for detecting genetically
modified organisms (GMOs).   We  are  now  establishing development programmes
to increase  our portfolio of DNA-based products.

"There  is  every reason for  optimism that the progress we  have already made
will establish successful businesses in both  DNA Analysis and Food Testing.

"The  Board  and  employees of Tepnel are committed to producing a  profitable
business.   Our  challenge  is  to   balance   the expenditure   of  our  cash
reserves  with  income generating activities.  We  believe  that  the  Company
is   now   well positioned  to  exploit  opportunities  in  the  life  science
research,  clinical  diagnostics,  food  and  environmental markets and we are
optimistic about the prospects for the year 2000."

                               
For further information, please contact:

Tepnel Life Sciences PLC                                   Tel:  0161 445 9457
Peter Raymond, Chairman                            Internet:  www.tepnel.co.uk
Michael Billingham, Commercial Director              E-mail: corp@tepnel.co.uk
Jeremy Lee, Finance Director

Rawlings Financial PR Limited                              Tel:  0113 242 1500
John Rawlings
Catriona Valentine



                              CHAIRMAN'S STATEMENT

During 1999, all of Tepnel's resources were focused  on business opportunities
with income generating potential and  I am  pleased to report that the Company
has made real  progress in building a base for future profits generation.

A  prototype  96  column  automated  DNA  purification  instrument was rapidly
developed  from  our  existing  instrumentation  platform.    This   prototype
was  well  received by an international audience at a major scientific meeting
in New Orleans in July 1999 and has since generated a great deal of commercial
interest.

Our  newly  formed  subsidiary,    Tepnel  BioSystems  Limited  purchased  two
businesses  in June 1999 - BioKits and Laboratory Services.   These  strategic
acquisitions  provide  us  with  a  profitable  vehicle  to  deliver  our  DNA
technologies to the food testing and related industries.

We  received  a  DTI  SMART  award to fund a combined technical and commercial
feasibility study on an innovative isothermal signal amplification technology,
which was developed in-house.

The DARAS patent was granted in the USA and is proceeding  to grant in Europe.
The SPA patent was also granted in the USA.


Results

A   loss   of #2.376 million  was  recorded  in the year  ended  30 June  1999
(1998: #2.587 million) on  sales of #174,000  (1998: #135,000), representing a
loss per share of 4.9 pence (1998: 5.3 pence).

DARAS sales were below budget but the Company  has been able to compensate for
this by effective cost controls.

We  have continued to keep tight control of our costs and cash reserves at the
year-end  were  #2.064 million (1998: #5.083 million).  Net cash  outflow  for
the year of #3 million  included  the  #1 million consideration  paid  for the
BioKits and Laboratory Services businesses.


Business Strategy

The Board believes that Tepnel will become a successful and profitable company
by  delivering  DNA  technologies  to  the  life  science  research,  clinical
diagnostics,  food  and  environmental testing markets.  This success  will be
achieved  by identifying the  best opportunities available to us and combining
our  in-house  capabilities with appropriate partners, including acquisitions,
to meet customer needs.

The  core  competence  of  the  Company  remains  the development of automated
systems  to  deliver  the  DNA-based  technologies  that the  market requires.
Purification is the first step  in  any DNA-based  analysis  and  we  estimate
that  the  global  DNA purification market is #500 million,  growing at 12-13%
per annum.  It  is our view  that we should seize this  opportunity  and so we
have developed a  96 column automated instrument for the  research market. The
response to our prototype at the New  Orleans meeting has confirmed this view.

We  intend to form commercial partnerships which will enable us  to  introduce
our first purification system  into  the  research  market,  generating  sales
of both  instrumentation  and  its associated  consumables and reagents.  Such
partnerships  will  also  lead  to  the  development  and commercialisation of
further instruments to address different  parts  of  the  market,  eg DNA from
blood.

The establishment of Tepnel BioSystems allows us to exploit opportunities that
exist for DNA-based technologies  in  the food and related markets through the
sale of kits  and  contract services.   We  will build on the existing  income
stream by expanding both the range and scope of that business through in-house
developments  and  partnerships.    Initial  targets  are  the  detection   of
genetically  modified  organisms  in  food  samples and  related applications,
such as determining the species  of origin of meat.

We  also  intend  to  obtain  licensing revenue from our portfolio of patented
technologies, the value of which increases  as more applications  reach  grant
in the  USA  and  Europe.   In  the future,  it  is  expected that Tepnel will
generate income and  profits from  technology  transfer and  licensing,  sales
of products such as instruments and kits, and contract services.


Developments since the year-end

Following  the  presentation  of  our  prototype  96  column  DNA purification
instrument,  we  have  entered  into discussions with a  number  of  potential
partners.    In  addition,  Tepnel's purification system is  based on magnetic
bead technology and, following a significant period of joint development work,
we acquired this technology in August 1999, ensuring that we now fully control
the reagent stream.

Tepnel  BioSystems has successfully merged  the  two  acquired businesses  and
is  already selling  a  range  of  DNA-based  kits  for detecting  genetically
modified organisms (GMOs).  We are now establishing development  programmes to
increase our  portfolio of DNA-based products.

There is every reason for optimism that the progress we have already made will
establish successful businesses in both  DNA Analysis and Food Testing.


Personnel

I  would  like  to thank all the Tepnel employees who have given positive  and
sustained  support  to  the  Company's  business  strategy.   It  is also with
pleasure that I  welcome  to  the Tepnel  group all of the 21 new employees of
Tepnel BioSystems Ltd.

I  am  continuing in my role as acting Chief Executive Officer of the Company,
during the current phase of commercialisation.  It  is  the  Board's intention
to recruit  a  suitably qualified and  experienced  Chief Executive as soon as
is  appropriate, when I will return to my non-executive role.


Outlook

The  Board  and  employees  of  Tepnel are committed to producing a profitable
business. Our challenge is to balance the expenditure  of  our  cash  reserves
with income generating activities.  We believe that the Company  is  now  well
positioned  to  exploit  opportunities  in the life science research, clinical
diagnostics,  food  and  environmental markets and we are optimistic about the
prospects for the year 2000.

Finally  it is  with pleasure that on behalf of all the  Tepnel directors  and
employees,  I  thank  our  shareholders  for  their faith  and  conviction  in
supporting Tepnel.  I  sincerely  hope  that  the commitment and investment in
time, money and personal skills,  produces the success that everyone  involved
with Tepnel deserves.

Peter Raymond
CHAIRMAN
6 October 1999



CONSOLIDATED PROFIT AND LOSS ACCOUNT
Year ended 30 June 1999

                                            Year to 30 June   Year to 30 June
                                                  1999              1998
                                             #000      #000     #000     #000
                                                      
Turnover                                                174               135
Cost of sales                                           (59)              (71)
                                                   --------          --------
Gross profit                                            115                64
                                                      
Research and development                   (1,553)            (1,936) 
Sales and marketing                          (531)              (598)   
Administrative expenses                      (667)              (576)   
                                         --------           --------
                                                     (2,751)           (3,110)
                                                   --------          --------
Operating loss                                       (2,636)           (3,046)
Interest receivable                                     260               459
                                                   --------          --------
Loss both before and after
taxation for the year                                (2,376)           (2,587)
                                                   --------          --------
                                                              
Loss per share                                         4.9p              5.3p
Diluted loss per share                                 4.9p              5.3p
                                                              

Notes:

1. The Group's activities for the year relate to continuing operations and all
   recognised gains and losses are included above.

2. A subsidiary  Company, Tepnel BioSystems Limited, completed the acquisition
   of  the  trade  and  assets  of  a food diagnostics and laboratory services
   business on 18 June 1998.  The effect of the acquisitions on the results of
   the group for the year is not significant.

3. The Directors do not recommend the payment of a dividend.

4. The basic loss per share has been calculated on the following basis:

                            Year to 30 June 1999         Year to 30 June 1998
                                         Average                      Average
                               Loss    number of           Loss     number of
                              #'000     ordinary          #'000      ordinary
                                          shares                       shares
              
              Basic          (2,376)  48,794,379         (2,587)   48,694,402

In  both  years  the diluted loss per share is  the same as the basic loss per
share.



CONSOLIDATED BALANCE SHEET
At 30 June 1999

                                             As at 30 June      As at 30 June 
                                                  1999              1998
                                             #000      #000     #000     #000
                                                              
Fixed assets                                                  
Intangible assets                                     1,091               542
Tangible assets                                         350               349
                                                   --------          --------
                                                      1,441               891
                                                          
Current assets                                            
Stocks                                        451                405         
Debtors and prepayments                       279                250         
Investments                                    25                 61          
Cash at bank and in hand                    2,064              5,083       
                                         --------           --------
                                            2,819              5,799       
Creditors: amounts falling
due within one year                           531                595         
                                                   --------          --------
Net current assets                                    2,288             5,204
                                                   --------          --------
Total assets less                      
current liabilities                                   3,729             6,095
                                                   ========           =======
                                                      
Capital and reserves                                  
Called up share capital                                 488               487
Share premium account                                15,990            15,981
Profit and loss account                             (12,749)          (10,373)
                                                   --------          --------
Shareholders' funds                                   3,729             6,095
                                                   ========          ========
 
Notes:
                                                     
1. All items under capital and reserves are equity

2. On  18  June 1999  the  Company completed  the acquisition of the trade and
   assets of  the food diagnostics  and laboratory services business at a cash
   cost  of  #1,000,000  and  acquisition  costs of  #52,122.  The  net assets
   acquired was #502,630 giving rising goodwill of #549,492.



CONSOLIDATED CASH FLOW STATEMENT
Year ended 30 June 1999

                                                   Year to            Year to
                                                   30 June            30 June
                                                      1999               1998
                                                      #000               #000
                                                              
Reconciliation of operating loss to net                       
cash flow from operating activities                           
Operating loss                                      (2,636)            (3,046)
Depreciation                                           159                137
Amortisation                                             1                  -
Decrease/(increase) in stocks                          186               (391)
Decrease/(increase) in debtors                          86                (27)
(Increase)/decrease in creditors                       (64)               239
(Profit)/loss on disposal of fixed assets               (2)                25
Release on provision for diminution in          
value of assets                                          -               (113)
                                                  --------           --------
Net cash outflow from operating activities          (2,270)            (3,176)
                                                  ========           ========
                                                    
                                                     #'000              #'000
Cash flow statement                                 
Net cash outflow from operating activities          (2,270)            (3,176)
Returns on investments                                 260                459
Acquisitions and disposals                          (1,052)                 -
Investing activities                                    33               (258)
Management of liquid resources                       2,999              2,849
Financing                                               10                  9
                                                  --------           --------
Decrease in cash                                       (20)              (117)
                                                  ========           ========
                                                    
                                                     #'000              #'000
Reconciliation of net cash flow to                  
movements in net funds                                        
Decrease in cash                                       (20)              (117)
Cash inflow from short term deposits                (2,999)            (2,849)
                                                  --------           --------
Change in net funds resulting from cash flow        (3,019)            (2,966)
Net funds at the beginning of year                   5,083              8,049
                                                  --------           --------
Net funds at the end of year                         2,064              5,083
                                                  ========           ========

Notes:

Nature of Preliminary Announcement

The financial information supporting  the  preliminary  announcement  relating
to  Tepnel  Life Sciences  PLC  does  not  constitute  statutory  accounts  as
defined by Section  240  of  the Companies  Act 1985. The abridged comparative
financial  information  for the  year to 30 June 1998 has been  based  on  the
statutory accounts of Tepnel Life Sciences PLC for the year  to  30 June 1998.
These accounts have been reported  on by  the Company's auditors and delivered
to the Registrar  of  Companies.  The  report of the auditors was  unqualified
and  did  not contain a statement under section 237(2) or (3) of the Companies
Act 1985.

The financial  information for  the  year to 30 June 1999 has been prepared on
the  basis  of the accounting policies set out in the Company's  accounts  for
the  year to 30 June 1998, with the following two exceptions. Goodwill arising
on  acquisition  is  amortised  through  the  profit and loss account over the
directors' estimate of its  useful economic life - ranging from five to twenty
years.   Depreciation on plant, equipment, fixtures and fittings is calculated
at 20 - 33.33% per annum.  The auditors  have not yet reported on the accounts
for the year ended 30 June  1999.  The statutory accounts for the year will be
delivered to the Registrar of Companies following the Company's Annual General
Meeting.


END

FR FSEESIUUUFSS


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