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By Chris Wack
Pfizer Inc. (PFE) said Wednesday that it saw positive top-line results from a Phase 3 pivotal study for its investigational oral Janus kinase 1 inhibitor, abrocitinib, in patients aged 12 and older with moderate to severe atopic dermatitis.
The pharmaceutical company said in a release that top-line results showed that by week 12, the percentage of patients achieving each co-primary efficacy endpoint and each key secondary endpoint with either dose of abrocitinib was statistically significantly higher than placebo.
Pfizer said the results demonstrate response to treatment for a statistically significant number of patients during the first two to four weeks following the first dose.
The company said that safety results showed that both doses of abrocitinib were well-tolerated and there were no unexpected safety events. The discontinuation rates due to an adverse event were low in each treatment arm compared to placebo.
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(END) Dow Jones Newswires
May 15, 2019 07:15 ET (11:15 GMT)
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