Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.
On November 2, 2020, the Board of Directors
(the “Board”) of Entasis Therapeutics Holdings Inc. (the “Company”) , approved a restricted stock unit-based
program (“the RSU Program”) to provide a long-term incentive to the Company’s employees, including the members
of the executive leadership team (“ELT”). Pursuant to the RSU Program and the Company’s 2018 Equity Incentive
Plan (the “2018 Plan”), the Company will grant a time-based restricted stock unit (“TRSU”) award to every
employee, which will vest 50% on the first anniversary of the vesting commencement date, or the date of grant of TRSUs to the non-ELT
employees (the “Vesting Commencement Date”) and 50% on the second anniversary of the Vesting Commencement Date, provided
that the recipient is still employed by or providing services to the Company on each vesting date. The Vesting Commencement Date
is November 2, 2020. In addition, pursuant to the RSU Program and the 2018 Plan, the Company will grant an additional performance-based
restricted stock unit (“PRSU”) award to members of the ELT that is conditioned upon the determination of the Compensation
Committee of the Board (the “Compensation Committee”) that the Company has received positive data from its ATTACK (Acinetobacter
Treatment Trial Against Colistin) Phase 3 registration clinical trial evaluating sulbactam-durlobactam
in Acinetobacter infections, including carbapenem-resistant strains. The PRSU award will vest in equal parts, provided that
the recipient is still employed by or providing services to the Company on each vesting date, upon (a) the decision by the Compensation
Committee that the Company has received positive data from the ATTACK Trial and (b) the one-year anniversary of such determination.
Upon vesting, the TRSUs and PRSUs may be settled in shares of common stock of the Company, or in cash equal to the fair market
value of the number of vested shares, at the election of the Company.
Pursuant to the RSU Program, Manoussos Perros,
Ph.D., the Chief Executive Officer of the Company, will be eligible to receive a total of 145,000 restricted stock units (“RSUs”),
consisting of 72,500 TRSUs and 72,500 PRSUs. Michael Gutch, the Chief Financial Officer and Chief Business Officer of the Company,
will be eligible to receive a total of 50,000 RSUs, consisting of 25,000 TRSUs and 25,000 PRSUs under the RSU Program. The RSU
awards to Dr. Perros and Dr. Gutch will be made on or about January 15, 2021, if the Share Reserve (as defined in the 2018 Plan)
is increased on January 1, 2021 in accordance with the annual increase as set forth in the 2018 Plan.
In connection with the adoption of the RSU
program, the Board adopted a form of Restricted Stock Unit Grant Notice (Time-Based) (the “Time-Based RSU Grant Notice”),
a form of Restricted Stock Unit Grant Notice (Performance-Based) (the “Performance-Based RSU Grant Notice”), and form
of Restricted Stock Unit Grant Agreement (the “RSU Award Agreement”). The foregoing summaries of the RSU Program, the
TRSU and the PRSU do not purport to be complete and are subject to, and qualified in their entirety by, the full text of the Time-Based
RSU Grant Notice, the Performance-Based RSU Grant Notice and the RSU Award Agreement, copies of which are filed as Exhibits 10.1,
10.2 and 10.3, respectively, to this Current Report on Form 8-K (the “Current Report”) and are incorporated herein
by reference.
Forward-Looking Statements
Any
statements in this Current Report about the Company’s future expectations, plans and prospects, including statements about
the availability of data from the ATTACK Trial, and other statements containing the words such as “may,” “will,”
“expect,” “plan,” “anticipate,” “estimate,” “intend” and
similar expressions, constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of
1995. Such statements are subject to numerous important factors, risks and uncertainties that may cause actual events or
results to differ materially from current expectations and beliefs and the risks more fully
described in the Company’s filings with the SEC, including those set forth in Part I, Item 1A, “Risk Factors,”
in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2019 and those set forth in Part II, Item
1A, “Risk Factors” in the Company’s Quarterly Reports on Form 10-Q. Forward-looking statements contained in this
Current Report are made as of this date, and except as required by law, the Company assumes no obligation to update any forward-looking
statements contained herein to reflect any change in expectations, even as new information becomes available.