ADVENTRX to Present Positive Thiovir Antiviral Activity Results
April 26 2006 - 5:00AM
PR Newswire (US)
SAN DIEGO, April 26 /PRNewswire-FirstCall/ -- ADVENTRX
Pharmaceuticals, Inc. (AMEX:ANX) announced today that its abstract
was accepted for an oral presentation at the 14th International
Symposium on HIV and Emerging Infectious Diseases (ISHEID) program.
The abstract outlines preclinical results demonstrating broad
antiviral activity of Thiovir against multiple subtypes of avian
and human influenza A and human influenza B virus, two types of
herpes simplex virus, HSV-1 and HSV-2, and multiple HIV strains.
The abstract is entitled "Thiovir exhibits broad-spectrum antiviral
activity against human and avian influenza viruses, human
immunodeficiency viruses, and herpes simplex viruses". Shani
Waninger, Ph.D., associate director for research and development
for ADVENTRX and lead author on the abstract, will deliver the talk
on Thursday, June 22 in the "new antiretroviral drugs" plenary
session. The ISHEID conference takes place June 21-23, 2006 in
Toulon, France. For more information, visit the conference web site
at http://www.isheid.com/. "We look forward to announcing these
results demonstrating Thiovir activity against a range of viruses
including herpes and influenza," said Dr. Waninger. "In addition to
the work that will be presented at the ISHEID conference, results
are forthcoming from ongoing Thiovir preclinical experiments."
ADVENTRX currently plans to file an investigational new drug
application (IND) with the US Food and Drug Administration (FDA) in
order to initiate a Phase I/II clinical trial using Thiovir to
treat HIV/AIDS in 2006. In addition, the Company is currently
investigating development options for Thiovir to treat herpes
infections and as a potential treatment for avian influenza. About
Thiovir Thiovir is a broad spectrum antiviral drug that has been
shown in preclinical tests to inhibit HIV, influenza A and herpes
viruses. Thiovir is a pyrophosphate analogue reverse transcriptase
inhibitor designed for oral delivery as a component of highly
active antiretroviral therapy (HAART) for HIV/AIDS. Thiovir is a
prodrug for foscarnet that delivers both the active drug TPFA
(thiophosphonoformate) and the active metabolite PFA (foscarnet).
About ADVENTRX ADVENTRX Pharmaceuticals is a biopharmaceutical
research and development company focused on introducing treatments
for cancer and infectious diseases that surpass the performance and
safety of existing drugs, by addressing significant problems such
as drug metabolism, toxicity, bioavailability and resistance. More
information can be found on the Company's Web site at
http://www.adventrx.com/. Forward-Looking Statement This press
release contains forward-looking statements, within the meaning of
the "safe harbor" provisions of the Private Securities Litigation
Reform Act of 1995, regarding ADVENTRX. Such statements are made
based on management's current expectations and beliefs. Actual
results may vary from those currently anticipated based upon a
number of factors, including uncertainties inherent in the drug
development process, the timing and success of clinical trials, the
validity of research results, and the receipt of necessary
approvals from the FDA and other regulatory agencies. For a
discussion of such risks and uncertainties, which could cause
actual results to differ from those contained in the
forward-looking statements regarding ADVENTRX, see the section
titled "Risk Factors" in ADVENTRX's last annual report on Form
10-K, as well as other reports that ADVENTRX files from time to
time with the Securities and Exchange Commission. All
forward-looking statements regarding ADVENTRX are qualified in
their entirety by this cautionary statement. ADVENTRX undertakes no
obligation to release publicly any revisions, which may be made to
reflect events or circumstances after the date hereof. DATASOURCE:
ADVENTRX Pharmaceuticals, Inc. CONTACT: Andrea Lynn of ADVENTRX
Pharmaceuticals, +1-858-552-0866 Web site: http://www.isheid.com/
Web site: http://www.adventrx.com/ Company News On-Call:
http://www.prnewswire.com/gh/cnoc/comp/920134.html
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