DOW JONES NEWSWIRES 
 

Wyeth (WYE) posted flat first-quarter net income as the stronger dollar pushed sales down modestly, but earnings topped expectations despite woes for its top-selling antidepressant Effexor.

The drug maker early this year agreed to be acquired by rival Pfizer Inc. (PFE) in a deal currently valued at $62.5 billion. Some big drug makers see mega-mergers as a way to survive a host of industry obstacles including generic competition, difficulty in developing new drugs and blockbuster drugs coming off patent.

The proposed combination of Pfizer and Wyeth, which has been establishing a foothold in biotechnology and vaccines, would create a behemoth selling everything from pills, biotech drugs and vaccines to medicines for animals.

Wyeth reported net income edged up $1.3 million to $1.2 billion, with per-share earnings flat at 89 cents. Excluding items such as restructuring and merger-related charges, earnings rose to 95 cents from 94 cents.

Revenue fell 6% to $5.4 billion, but was up 2% excluding the stronger dollar's impact, amid growth of Enbrel outside the U.S. and Canada, Prevnar and its nutritional products.

Analysts were expecting earnings, excluding items, of 88 cents a share on revenue of $5.52 billion.

Gross margin rose to 75.6% from 73.8% on the stronger dollar.

Pharmaceutical revenue dropped 6% to $4.49 billion and Effexor logged a 20% decline. Prevnar, a vaccine against pneumococcal disease, saw a 7% sales rise, and climbed 19% excluding currency effects. Rheumatoid-arthritis drug Enbrel, which Wyeth co-markets with Amgen Inc. (AMGN), had a 3% sales rise, but was up 23% excluding currency effects.

Wyeth shares closed Tuesday at $42.25.

-By Mike Barris, Dow Jones Newswires; 201-938-5658; mike.barris@dowjones.com