TIDMMEDG 
 
Medgenics, Inc. 
                         ('Medgenics' or the 'Company') 
 
 
16 February 2009 
 
The Board of Medgenics announces that it was informed by Joel Kanter (a director 
of  the  Company) on 13 February 2009 that, on that same day, warrants  held  by 
certain affiliates in which he is interested had been exercised pursuant to  the 
extension of the warrant repricing programme announced on 5 February 2009.   Mr. 
Kanter's relevant affiliates are: 
 
1.   the  Kanter  Family  Foundation, a not-for-profit corporation  of  which  Mr. 
     Kanter  is  the  President  and a Director.  This affiliate  has  exercised 
     warrants at the reduced exercise price of US $0.0375 each entitling  it  to 
     857,007 common shares of par value of US $0.0001 each ("Common Shares") and 
     96,413  warrants to subscribe for and purchase further Common  Shares.  The 
     warrants  ("Bonus Warrants") are exercisable at a price  of  US  $0.25  per 
     Common Share from 13 February 2009 and expire on 13 February 2012. 
 
2.   Chicago  Private  Investments, Inc, a corporation  indirectly  owned  by  the 
     Kanter Trusts (see note (iii) below). This affiliate has exercised warrants 
     at  their  original exercise price of US $0.000005 entitling it to  197,914 
     Common Shares and 3 Bonus Warrants. 
 
The  aggregate  cash amount received by the Company in respect of these  warrant 
exercises was US $32,139. 
 
These  new  Common  Shares  are  deemed to be restricted  shares  under  the  US 
securities laws and will be admitted to AIM pursuant to the block listing  which 
was  applied for on 4 December 2007 and will trade under the TIDM (ticker) MEDG. 
The  Company  announces  that,  as at the date  of  this  announcement,  it  has 
118,420,694  Common Shares in issue. The percentage of Common  Shares  in  issue 
that are not in public hands is 30.0%. 
 
Following  the above warrant exercises, Joel Kanter is interested in 14,053,487* 
Common  Shares  representing approximately 11.9% of the Company's  issued  share 
capital. 
 
Notes: 
* Included in the interests of Joel Kanter are his interests in: 
 
 (i)  1,806,233 Common Shares held by the Kanter Family Foundation, an Illinois 
      not-for-profit corporation of which Mr. Kanter is the President and  is  a 
      Director; 
 
 (ii) 7,605,985  Common Shares held by CIBC Trust Company  (Bahamas)  Limited 
      ("CIBC").  CIBC is the trustee of Settlement T-555 (the "CIBC Trust").  The CIBC 
      Trust was established for the benefit of various descendants of (i) Helen and 
      Henry  Krakow,  and  (ii) Beatrice and Morris Kanter.   Mr.  Kanter  is  a 
      discretionary beneficiary of the CIBC Trust.  Sole voting and investment control 
      of the Common Shares owned by the CIBC Trust is vested in CIBC as trustee of the 
      CIBC Trust; 
 
 (iii)4,400,807 Common Shares held by Chicago Investments, Inc. ("CII"). 
      CII is a majority-owned subsidiary of Chicago Holdings, Inc. ("CHI"). CHI is 
      majority owned by various trusts (together the "Kanter Trusts") established for 
      the benefit of various descendants of (i) Helen and Henry Krakow, and (ii) 
      Beatrice and Morris Kanter. Joel Kanter is a discretionary beneficiary of some, 
      but not all, of the Kanter Trusts.  Sole voting and investment control of the 
      Common Shares owned by CII is vested in Mr. Kanter's brother, Joshua Kanter, as 
      President of CII; and 
 
 (iv) 240,462 Common Shares held by Chicago Private Investments, Inc ("CPI"). 
      CPI is a wholly owned subsidiary of The Holding Company ("THC").  THC is owned 
      by Kanter Trusts.  Sole voting and investment control of the shares of the 
      Company owned by CPI is vested in Mr. Kanter's brother, Joshua Kanter, as 
      President of CPI. 
 
      For  the  purposes  of applicable US Securities Laws and regulations,  Mr. 
      Kanter  disclaims  all  beneficial and pecuniary interest  to  the  Common 
      Shares  held by CII and CPI and the CIBC Trust.  Such disclaimer does  not 
      affect  Mr.  Kanter's  status  as a discretionary  beneficiary  under  the 
      Kanter Trusts or the CIBC Trust. 
 
Following  the  exercise of these warrants, Joel Kanter  is  interested  in  the 
following number of warrants: 
 
Warrant     Number       Issue      Expiry        Exercise 
Name                      date        date           price 
                                                      US $ 
 
W          3,059,192   31/03/06    31/03/11          0.071 
W          1,069,575   23/10/06    23/10/11          0.117 
RS        14,080,734   31/03/06    31/03/11       0.023634 
Bonus        450,000   30/01/09    30/01/12           0.25 
Bonus         96,416   13/02/09    13/02/12           0.25 
=---------------------------------------------------------------------- 
Total     18,755,917 
 
The total warrants outstanding in the Company as of the date of this 
announcement are as follows: 
 
Warrant      Date of       No. of    Exercise     Expiry Date 
Type           Issue       Common   Price per 
                           Shares      Common 
                                        Share 
RS          31.03.06   15,680,818   US $0.0005       31.03.11 
RS          31.03.06   36,481,902   US $0.071        31.03.11 
RW          31.03.06    1,388,821   US $0.000005     31.03.11 
RW          22.10.08       22,588   US $0.000005     31.03.11 
X           31.03.06    4,278,298   US $0.071        24.03.10 
X           31.03.06      533,183   US $0.071        31.03.11 
W           31.03.06   21,397,303   US $0.071        31.03.11 
W           10.04.06    1,026,792   US $0.071        10.04.11 
W           14.06.06    1,069,575   US $0.071        14.06.11 
W           23.10.06   19,036,479   US $0.117        23.10.11 
W            9.02.07      705,919   US $0.071        31.03.11 
W           13.03.07      705,919   US $0.071        31.03.11 
W           13.03.06    2,117,758   US $0.071        21.06.11 
W           13.03.07    1,336,968   US $0.117        23.10.11 
W           31.05.07    1,329,310   US $0.164        31.05.12 
W           13.08.07      402,246   US $0.164        13.08.12 
W           17.08.07       64,174   US $0.164        17.08.12 
W            4.12.07      252,334   US $0.164        13.08.12 
W            4.12.07    1,259,810   US $0.164         4.12.12 
W            4.12.07    2,997,420   US $0.194         4.12.12 
W            4.12.07      570,992          10p        4.12.12 
W           19.10.08      305,598   US $0.164        17.08.12 
Platinum    13.08.07    1,909,618   US $0.164        31.08.12 
Platinum     4.12.07    1,604,362   US $0.164         4.12.12 
Platinum     4.12.07       23,183         10p         4.12.12 
Platinum     1.12.08    2,353,064   US $0.194         4.12.13 
Bonus        30.1.09    1,196,728   US $0.25          30.1.12 
Bonus        13.2.09       96,416   US $0.25          13.2.12 
=---------------------------------------------------------------------- 
Total                 120,147,578 
 
 
The Company also confirms that the warrant repricing programme as announced on 
17 December 2008 and as extended to 13 February 2009 (as announced on 5 February 
2009) is now complete and no further extensions to the warrant repricing 
programme will be granted. The exercise price of any warrants that were not 
exercised prior to 13 February 2009 have all reverted to their original price as 
stated in this announcement. 
 
For further information, contact: 
 
Medgenics, Inc.                                   +972 4 902 8900 
Dr. Andrew L. Pearlman 
 
Blomfield Corporate Finance (Nominated adviser)   +44 207 489 4500 
James Pinner or 
Alan MacKenzie 
 
SVS Securities plc (Broker)                       +44 207 638 5600 
Ian Callaway 
 
Grayling Global                                   +44 207 255 5406 
Jonathan Shillington or 
Alistair Scott 
 
NOTES TO EDITORS: 
 
Medgenics,  Inc.  is a clinical-stage biopharmaceutical company  developing  its 
unique  tissue-based  Biopump  platform technology to  provide  sustained-action 
protein therapy for the treatment of a range of chronic diseases. 
 
Medgenics currently has two products in development based on this technology: 
 
� EPODURE - producing erythropoietin (EPO) to treat anaemia 
� INFRADURE - producing interferon-alpha (IFN-a) to treat hepatitis C 
 
The Company has demonstrated proof of concept of the Biopump treatment procedure 
in  a  clinical trial of EPODURE in anaemic subjects. The Company's  Phase  I/II 
clinical  trial for its long-acting version of EPODURE, designed to produce  and 
deliver  a therapeutic dose of EPO steadily for six months or more commenced  in 
August  2008.  Medgenics plans to follow with a clinical trial of  INFRADURE  in 
2009. 
 
Medgenics  intends to develop its innovative products and bring them  to  market 
via  multiple  strategic partnerships with major pharmaceutical  and/or  medical 
device companies, starting with EPODURE and INFRADURE. 
 
Beyond these, Medgenics plans to develop and/or out-license a pipeline of future 
Biopump  products targeting the large and rapidly growing global protein therapy 
market, which is forecast to reach US $87 billion by 2010. Other potential areas 
include multiple sclerosis (interferon-B), haemophilia (Factor VIII), paediatric 
growth hormone deficiency (human growth hormone) and diabetes (insulin). 
 
Founded in 2000, Medgenics is a US-incorporated company with major operations in 
Misgav,  Israel.  Medgenics  was admitted to the London  AIM  in  December  2007 
(AIM:MEDG and AIM:MEDU). 
 
www.medgenics.com 
 
CAUTIONARY NOTICE REGARDING FORWARD-LOOKING STATEMENTS 
This  release contains forward-looking statements, which include all  statements 
other  than statements of historical fact, including (without limitation)  those 
regarding  the  Company's  financial  position,  business  strategy,  plans  and 
objectives  of  management  for future operations. These  statements  relate  to 
future   events,   prospects,   developments  and  strategies.   Forward-looking 
statements  are sometimes identified by their use of the terms and phrases  such 
as "estimate," "project," "intend," "forecast," "anticipate," "plan," "planning, 
"expect," "believe," "will," "will likely," "should," "could," "would," "may" or 
the  negative of such terms and other comparable terminology. All such  forward- 
looking  statements are based on current expectations and are subject  to  risks 
and  uncertainties. Should any of these risks or uncertainties  materialize,  or 
should  any  of  the Company's assumptions prove incorrect, actual  results  may 
differ  materially from those included within these forward-looking  statements. 
Accordingly,  no  undue  reliance  should be  placed  on  these  forward-looking 
statements,  which  speak  only  as  of the date  made.  The  Company  expressly 
disclaims  any obligation or undertaking to disseminate any updates or revisions 
to  any forward-looking statements contained herein to reflect any change in the 
Company's  expectations with regard thereto or any change in events,  conditions 
or  circumstances on which any such statements are based. As a result  of  these 
factors,  the  events described in the forward-looking statements  contained  in 
this release may not occur. 
 
-END- 
 

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