FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Yankton Kevin Bruce
2. Date of Event Requiring Statement (MM/DD/YYYY)
8/5/2021 

3. Issuer Name and Ticker or Trading Symbol

Twist Bioscience Corp [TWST]
(Last)        (First)        (Middle)

C/O TWIST BIOSCIENCE CORPORATION, 681 GATEWAY BLVD.
4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                          _____ 10% Owner
___X___ Officer (give title below)        _____ Other (specify below)
Chief Accounting Officer /
(Street)

SOUTH SAN FRANCISCO, CA 94080      

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed(MM/DD/YYYY)
 

6. Individual or Joint/Group Filing(Check Applicable Line)

_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 1601 (1)D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(MM/DD/YYYY)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date ExercisableExpiration DateTitleAmount or Number of Shares
Employee Stock Option (right to buy)  (2)8/1/2031 Common Stock 2551 $117.59 D  

Explanation of Responses:
(1) Represents a restricted stock unit award ("RSU") of which 25% of the total number of RSUs vest on the first anniversary of May 17, 2021 and 1/16th of the total number of RSUs vest on each quarterly anniversary thereafter, for a total vesting period of 48 months, subject to the Reporting Person's continuous service through each vesting date.
(2) 25% of the shares subject to the option vest and become exercisable on the one (1) year anniversary of May 17, 2021 and 1/48 of the shares subject to the option vest and become exercisable monthly thereafter, subject to the Reporting Person's continuous service through each vesting date.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Yankton Kevin Bruce
C/O TWIST BIOSCIENCE CORPORATION
681 GATEWAY BLVD.
SOUTH SAN FRANCISCO, CA 94080


Chief Accounting Officer

Signatures
/s/ William Solis, Attorney-in-Fact for Kevin B. Yankton8/9/2021
**Signature of Reporting PersonDate

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