- Total revenue of $28 million, up from $11 million in Q2
2020
- Total programs under contract of 138, up 82% from Q2 2020
- Net loss of ($0.01) per share (basic and diluted) compared to
net earnings of $0.03 per share (basic and diluted) in
Q2 2020
AbCellera (Nasdaq: ABCL), a technology company with a
centralized operating system for next-generation antibody
discovery, today announced financial results for the second quarter
of 2021. All financial information in this press release is
reported in U.S. dollars, unless otherwise indicated.
“This quarter we delivered strong growth across key performance
indicators related to our partnership business, including new
programs under contract, program starts, and new molecules in the
clinic,” said Carl Hansen, Ph.D., CEO of AbCellera. “We continue to
drive value in our partnership business by building a diversified
portfolio of potential future royalty streams across a broad range
of indications and antibody modalities. We are also extending this
model to create opportunities to deepen our position with assets
that can provide economics similar to an internal pipeline while
staying focused on preclinical discovery and development.”
Q2 2021 Business Summary
- Earned $27.6 million in total revenue, including $22.2 million
in milestones and royalties.
- Incurred net loss of $2.3 million, compared to generating net
earnings of $6.7 million in Q2 2020.
- Added 19 programs under contract with four new partners,
resulting in a cumulative total of 138 programs under contract with
33 different partners.
- Started discovery on six programs, bringing the cumulative
number of program starts to 60.
- Confirmed three new molecules advanced into the clinic,
bringing the cumulative total to four.
- U.S. shipments of the AbCellera-discovered and Eli
Lilly-developed bamlanivimab, administered together with etesevimab
for COVID-19, were halted in June 2021 because of the prevalence of
resistant variants at the time (Beta and Gamma). Preclinical data
demonstrate that bamlanivimab and etesevimab administered together
retain neutralization activity against variants currently in
circulation in many countries, including the Delta variant which is
now the most prevalent variant in the U.S.
- A second AbCellera-discovered therapeutic antibody for
COVID-19, bebtelovimab (LY-CoV1404), which has been shown in
preclinical studies to be highly potent and effective against
variants of concern, including the Delta variant, was advanced into
Phase 2 clinical testing by Eli Lilly.
- Expanded leadership team with the appointment of Neil Berkley
as Chief Business Officer.
Key Business Metrics
Metric
June 30, 2020
June 30, 2021
Change %
Number of discovery partners
25
33
32
%
Programs under contract, cumulative
76
138
82
%
Program starts, cumulative
48
60
25
%
Molecules in the clinic
1
4
300
%
AbCellera added 19 discovery programs in Q2 to reach a
cumulative total of 138 discovery programs as of June 30, 2021 (up
82% from 76 on June 30, 2020), that are either completed, in
progress, or under contract with 33 different partners (up from 25
on June 30, 2020). AbCellera started discovery on an additional six
programs in Q2 to reach a cumulative total of 60 program starts (up
from 48 on June 30, 2020). Our partners advanced three additional
molecules into the clinic in Q2 2021, bringing the cumulative total
to four.
Discussion of Q2 2021 Financial Results
Three months ended
June 30,
Change
Six months ended
June 30,
Change
2020
2021
Amount
%
2020
2021
Amount
%
(in thousands, except
percentages)
(in thousands, except
percentages)
Revenue
Research fees
$
8,228
$
5,215
$
(3,013
)
-37
%
$
12,885
$
9,201
$
(3,684
)
-29
%
Licensing revenue
-
263
263
N/A
-
20,522
20,522
N/A
Milestone payments
3,000
1,000
(2,000
)
-67
%
3,000
8,000
5,000
167
%
Royalty revenue
-
21,165
21,165
N/A
-
192,661
192,661
N/A
Total revenue
$
11,228
$
27,643
$
16,415
146
%
$
15,885
$
230,384
$
214,499
1350
%
- Revenue – Total revenue was $27.6 million, up from $11.2
million in Q2 2020. Sales of bamlanivimab generated earned
royalties of $21.2 million. Milestone payments totalled $1.0
million and licensing revenue contributed $0.3 million. The
partnership business produced research fees of $5.2 million,
compared to $8.2 million in Q2 2020, which is attributable to the
reduction in work associated with COVID-19 antibody discovery.
- Royalty Fees – Royalty fees payable to the National
Institutes of Health on bamlanivimab were $3.6 million.
- Research & Development (R&D) Expenses – R&D
expenses were $15.0 million, compared to $9.1 million in Q2 2020,
reflecting continuing strong investments in the capacity and
capabilities of AbCellera’s discovery and development
platform.
- Sales & Marketing (S&M) Expenses – S&M
expenses were $1.3 million, compared to $0.5 million in Q2
2020.
- General & Administrative (G&A) Expenses –
G&A expenses were $11.2 million, compared to $1.5 million in Q2
2020, with the increase driven primarily by investments to support
the growth of the company, non-cash stock-based compensation in
line with publicly listed companies, and protecting our
intellectual property.
- Net Loss – Net loss was $2.3 million, or ($0.01) per
share on both a basic and diluted basis compared to net earnings of
$6.7 million, or $0.03 per share on a basic and diluted basis in Q2
2020.
- Liquidity – $792.6 million of cash and cash equivalents
and $64.9 million in accounts receivable and accrued accounts
receivable.
Conference Call and Webcast
AbCellera will host a conference call and live webcast to
discuss these results today at 2:00 p.m. Pacific Daylight Time
(5:00 p.m. Eastern Daylight Time).
The live webcast of the earnings conference call can be accessed
on the Events and Presentations section of AbCellera’s Investor
Relations website. A replay of the webcast will be available
through the same link following the conference call.
About AbCellera Biologics Inc.
AbCellera is a technology company that searches, decodes, and
analyzes natural immune systems to find antibodies that its
partners can develop into drugs to prevent and treat disease.
AbCellera partners with drug developers of all sizes, from large
pharmaceutical to small biotechnology companies, empowering them to
move quickly, reduce costs, and tackle the toughest problems in
drug development. To learn more, please visit
www.abcellera.com.
Definition of Key Business Metrics
We regularly review the following key business metrics to
evaluate our business, measure our performance, identify trends
affecting our business, formulate financial projections, and make
strategic decisions. We believe that the following metrics are
important to understand our current business. These metrics may
change or may be substituted for additional or different metrics as
our business develops. For example, as our business matures and to
the extent programs are discontinued, we anticipate updating these
metrics to reflect such changes.
Number of discovery partners represents the unique number
of partners with whom we have executed partnership contracts. We
view this metric as an indication of the competitiveness of our
technology stack and our current level of market penetration. The
metric also relates to our opportunities to secure programs under
contract.
Programs under contract represent the number of antibody
development programs that are under contract for delivery of
discovery research activities. A program under contract is counted
when a contract is executed with a partner under which we commit to
discover antibodies against one selected target. A target is any
relevant antigen for which a partner seeks our support in
developing binding antibodies. We view this metric as an indication
of commercial success and technological competitiveness. It further
relates to revenue from technology access fees. The cumulative
number of programs under contract with downstream participation is
related to our ability to generate future revenue from milestone
payments and royalties.
Program starts represent the number of unique programs
under contract for which we have commenced the discovery effort.
The discovery effort commences on the later of (i) the day on which
we receive sufficient reagents to start discovery of antibodies
against a target and (ii) the day on which the kick-off meeting for
the program is held. We view this metric as an indication of our
operational capacity to execute on programs under contract. It is
also an indication of the selection and initiation of discovery
projects by our partners and the resulting near-term potential to
earn research fees. Cumulatively, program starts with downstream
participation indicate our total opportunities to earn downstream
revenue from milestone fees and royalties in the mid- to
long-term.
Molecules in the clinic represent the count of unique
molecules for which an Investigational New Drug, or IND, New Animal
Drug, or equivalent under other regulatory regimes, application has
been approved based on an antibody that was discovered either by us
or by a partner using licensed AbCellera technology. Where the date
of such application approval is not known to us, the date of the
first public announcement of a clinical trial will be used for the
purpose of this metric. We view this metric as an indication of our
near- and mid-term potential revenue from milestone fees and
potential royalty payments in the long term.
Going forward, AbCellera intends to report on the molecules in
the clinic metric in place of the previously reported programs in
the clinic metric. The change is required to reflect two new
dynamics which we believe are important to our business:
- One program can yield multiple molecules, e.g. the single
COVID-19 antibody discovery program with Eli Lilly has produced
both bamlanivimab and bebtelovimab.
- As part of an acquisition, AbCellera may come to own stakes in
molecules for which the company is also entitled to milestone
payments and royalties although the discovery was not performed as
an AbCellera program, as is the case for several Trianni humanized
rodent license agreements.
As part of the change, we have raised the threshold for reaching
the clinic from IND application (or equivalent) to IND approval. We
believe this more stringent definition better reflects the common
understanding for achieving clinical status. The approval date is
also more likely to be known than the application date. We believe
this change will make our disclosures more consistent between
molecules. The change produces no difference to historical business
results. Until the second quarter of 2021, the previous metric of
programs in the clinic was identical to the new metric of molecules
in the clinic, with the COVID-19 antibody program and bamlanivimab
having been the first and only program and molecule to have reached
the clinic under either definition. AbCellera also intends to
disclose additional details about each molecule to the extent made
public or permitted by its partners. We believe that the updated
metric together with the additional list of molecules will give
investors a better understanding of AbCellera’s downstream
portfolio and bring AbCellera’s reporting in line with other public
companies with economic stakes in therapeutic molecules.
AbCellera Forward-looking Statements
This press release contains forward-looking statements,
including statements made pursuant to the safe harbor provisions of
the Private Securities Litigation Reform Act of 1995. The
forward-looking statements are based on management’s beliefs and
assumptions and on information currently available to management.
All statements contained in this release other than statements of
historical fact are forward-looking statements, including
statements regarding our ability to develop, commercialize and
achieve market acceptance of our current and planned products and
services, our research and development efforts, and other matters
regarding our business strategies, use of capital, results of
operations and financial position, and plans and objectives for
future operations.
In some cases, you can identify forward-looking statements by
the words “may,” “will,” “could,” “would,” “should,” “expect,”
“intend,” “plan,” “anticipate,” “believe,” “estimate,” “predict,”
“project,” “potential,” “continue,” “ongoing” or the negative of
these terms or other comparable terminology, although not all
forward-looking statements contain these words. These statements
involve risks, uncertainties and other factors that may cause
actual results, levels of activity, performance, or achievements to
be materially different from the information expressed or implied
by these forward-looking statements. These risks, uncertainties and
other factors are described under "Risk Factors," "Management's
Discussion and Analysis of Financial Condition and Results of
Operations" and elsewhere in the documents we file with the
Securities and Exchange Commission from time to time. We caution
you that forward-looking statements are based on a combination of
facts and factors currently known by us and our projections of the
future, about which we cannot be certain. As a result, the
forward-looking statements may not prove to be accurate. The
forward-looking statements in this press release represent our
views as of the date hereof. We undertake no obligation to update
any forward-looking statements for any reason, except as required
by law.
Source: AbCellera Biologics Inc.
AbCellera Biologics
Inc.
Condensed Consolidated
Statements of Income (Loss) and
Comprehensive Income
(Loss)
(All figures in U.S. dollars.
Amounts are expressed in thousands except share and per share
data)
(Unaudited)
Three months ended June
30,
Six months ended June
30,
2020
2021
2020
2021
Revenue:
Research fees
$
8,228
$
5,215
$
12,885
$
9,201
Licensing revenue
-
263
-
20,522
Milestone payments
3,000
1,000
3,000
8,000
Royalty revenue
-
21,165
-
192,661
Total revenue
11,228
27,643
15,885
230,384
Operating expenses:
Royalty fees
-
3,610
-
23,622
Research and development(1)
9,144
15,046
13,262
27,403
Sales and marketing(1)
547
1,295
984
3,869
General and administrative(1)
1,498
11,203
3,148
17,688
Depreciation and amortization
893
3,522
1,467
6,827
Total operating expenses
12,082
34,676
18,861
79,409
Income (loss) from operations
(854
)
(7,033
)
(2,976
)
150,975
Other (income) expense
Other (income) expense
293
(314
)
1,294
(645
)
Grants and incentives
(7,850
)
(4,646
)
(8,880
)
(7,794
)
Total other income
(7,557
)
(4,960
)
(7,586
)
(8,439
)
Net earnings (loss) before income tax
6,703
(2,073
)
4,610
159,414
Provision for income tax
-
250
-
44,516
Net earnings (loss)
$
6,703
$
(2,323
)
$
4,610
$
114,898
Foreign currency translation
adjustment
-
2,152
-
2,152
Comprehensive income (loss)
$
6,703
$
(171
)
$
4,610
$
117,050
Net earnings (loss) per share attributable
to common shareholders
Basic
$
0.03
$
(0.01
)
$
0.02
$
0.42
Diluted
$
0.03
$
(0.01
)
$
0.02
$
0.36
Weighted-average common shares
outstanding
Basic
152,326,424
272,196,107
152,091,589
270,953,541
Diluted
260,810,864
272,196,107
226,039,616
321,555,443
- Exclusive of depreciation and amortization
AbCellera Biologics
Inc.
Condensed Consolidated Balance
Sheet
(All figures in U.S. dollars.
Amounts are expressed in thousands except share data)
(Unaudited)
December 31, 2020
June 30, 2021
Assets
Current assets:
Cash and cash equivalents
$
594,116
$
792,571
Accounts receivable
903
2,799
Accrued accounts receivable
212,336
62,085
Other current assets
5,970
6,547
Total current assets
813,325
864,002
Long term assets:
Property and equipment, net
17,923
87,479
Intangible assets
115,153
110,223
Goodwill
31,500
31,500
Investments in and loans to equity
accounted investees
19,247
42,705
Other long-term assets
8,388
15,947
Total long-term assets
192,211
287,854
Total assets
$
1,005,536
$
1,151,856
Liabilities and shareholders'
equity
Current liabilities:
Accounts payable and other liabilities
$
20,195
$
18,276
Current portion of contingent
consideration payable
13,411
11,572
Income taxes payable
36,152
5,822
Accrued royalties payable
27,143
23,520
Deferred revenue
6,589
10,568
Total current liabilities
103,490
69,758
Long-term liabilities:
Operating lease liability
3,715
31,020
Deferred revenue and grant funding
25,894
46,618
Contingent consideration payable
9,148
9,614
Deferred tax liability
26,161
25,510
Other long-term liabilities
6,620
1,657
Total long-term liabilities
71,538
114,419
Total liabilities
175,028
184,177
Commitments and contingencies
Shareholders' equity:
Common shares: no par value, unlimited
authorized shares at December 31, 2020 and June 30, 2021:
269,497,768 and 276,982,678 shares issued and outstanding at
December 31, 2020 and June 30, 2021 respectively
710,387
714,758
Additional paid-in capital
5,919
21,669
Accumulated other comprehensive income
-
2,152
Accumulated earnings
114,202
229,100
Total shareholders' equity
830,508
967,679
Total liabilities and shareholders'
equity
$
1,005,536
$
1,151,856
AbCellera Biologics
Inc.
Condensed Consolidated
Statement of Cash Flows
(Expressed in thousands of
U.S. dollars)
(Unaudited)
Six months ended June
30,
2020
2021
Cash flows from operating
activities:
Net income
$
4,610
$
114,898
Cash flows from operating activities:
Depreciation of property and equipment
1,467
1,897
Amortization of intangible assets
-
4,930
Amortization of operating lease
right-of-use-assets
259
1,354
Stock-based compensation
1,843
13,900
Deferred tax expense
-
756
Other
(245
)
(419
)
Changes in operating assets and
liabilities:
Accounts and accrued research fees
receivable
(9,220
)
(28,339
)
Accrued royalties receivable
-
172,768
Income taxes payable
-
(30,330
)
Accounts payable and accrued
liabilities
1,510
(3,640
)
Deferred revenue
24,435
4,848
Accrued royalties payable
-
(3,623
)
Operating lease liabilities
372
(364
)
Deferred grant income
2,044
22,349
Other assets
(1,862
)
(3,757
)
Net cash provided by operating
activities
25,213
267,228
Cash flows from investing
activities:
Purchases of property and equipment
(4,286
)
(40,448
)
Purchase of intangible assets
(5,000
)
-
Repayment of loan to related parties
1,573
-
Receipt of grant funding
-
4,520
Long-term investments
-
(5,034
)
Investment in and loans to equity
accounted investees
-
(20,510
)
Net cash used in investing activities
(7,713
)
(61,472
)
Cash flows from financing
activities:
Repayment of long-term debt
(1,971
)
(1,823
)
Payment of contingent consideration
-
(2,550
)
Proceeds from long-term debt
15,509
872
Payment of liability for in-licensing
agreement
-
(5,000
)
Short-term borrowings
(387
)
-
Issuance of common shares pursuant to
exercise of stock options
251
1,883
Proceeds from issuance of preferred shares
- series A2 financing
74,682
-
Net cash provided by (used in) financing
activities
88,084
(6,618
)
Effect of exchange rate changes on cash
and cash equivalents
-
(683
)
Increase in cash and cash equivalents
105,584
198,455
Cash and cash equivalents, beginning of
period
7,553
594,116
Cash and cash equivalents, end of
period
$
113,137
$
792,571
View source
version on businesswire.com: https://www.businesswire.com/news/home/20210812005750/en/
Inquiries Media: Jessica Yingling, Ph.D.;
media@abcellera.com, +1(236) 521-6774 Business Development: Neil
Berkley; bd@abcellera.com, +1(604) 559-9005 Investor Relations:
Melanie Solomon; ir@abcellera.com, +1(778) 729-9116
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