By Sara Sjolin, MarketWatch

LONDON (MarketWatch) -- European stock markets moved lower on Wednesday as rate hikes in Turkey and South Africa failed to calm jitters over volatility in emerging markets and investors instead turned their attention to the outcome of the U.S. Federal Reserve Meeting.

Stoxx Europe 600 index dropped 0.6% to close at 322.38, after trading as high as 328.02 earlier in the day.

Last week, the benchmark posted its biggest weekly percentage loss since June after disappointing data from China created renewed fears of slower global growth, and triggered a sharp selloff in emerging-markets and risk assets.

In response to the volatility, the Turkish central bank late Tuesday raised its overnight lending rate to 12% from 7.75% to halt a slide in the lira and stem capital outflows. Amid the rout for emerging-market currencies, the Turkish lira (USDTRY) had dropped to a record low against the dollar and after an initial surge after the rate hike, it fell back in midday trade in Europe on Wednesday. A dollar bought 2.2391 lira, after trading as low as 2.1635 earlier in the day, according to FactSet data.

Turkish stocks also took a move lower, with the ISE National 100 index down 2.3% to 62,088.70. The weakness came as investors started to focus on the reason for the rate hike, Simon Smith, chief economist at FxPro, noted in emailed comments.

"Remember, Turkey did not raise rates because the economy is doing well. It did so because the currency is at an all-time low and inflation is high, and likely to rise further as a result," he added.

The South African Reserve Bank further increased rates on Wednesday in efforts to stem the turbulence in the rand.

The U.S. central bank was also in the spotlight. The Federal Reserve concludes its two-day meeting after the European market close and is widely expected to make another $10 billion cut in its quantitative-easing program, which will bring its monthly purchases down to $65 billion. Last month, the Fed announced it would take the first steps in tapering its aggressive bond-buying program, reducing it by $10 billion, after months of speculation. Wednesday's meeting marks the last with Ben Bernanke as Fed chairman before Janet Yellen takes the helm on Feb. 1.

U.S. stocks traded lower on Wall Street.

Back in Europe, corporate news was in focus. Shares of Mulberry Group PLC slid 27% after the luxury-goods firm warned its pretax profit for the year ending March 31 will be substantially below current market expectations.

Fiat SpA dropped 4.1% after the Italian car maker reported fourth-quarter earnings below expectations.

Shares of J Sainsbury PLC lost 2.3% after the supermarket chain said its chief executive, Justin King, has decided to step down and will be replaced by Mike Coupe.

On a more upbeat note, shares of Anglo American PLC put on 5.7% after the miner said production rose across most commodities in the fourth quarter.

Shares of Osram Licht AG gained 2.5% after the German light-bulb company confirmed its full-year outlook and reported a rise in profit for the first fiscal quarter.

Among country-specific indexes, France's CAC 40 index dropped 0.7% to 4,156.98 and the U.K.'s FTSE 100 index slipped 0.4% to 6,544.28. Germany's DAX 30 index fell 0.8% to 9,336.73.

On the data front, GfK's forward-looking indicator for Germany showed consumer sentiment rose to a six-year high in February, raising hopes that stronger domestic demand in Europe's largest economy will spur solid growth in the euro zone.

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