New Library Preparation Solutions Offer
Never Before Achieved Scale for the
Revio™ Sequencing System
MENLO
PARK, Calif., Feb. 5, 2024
/PRNewswire/ -- PacBio (NASDAQ: PACB), a leading developer of
high-quality, highly accurate sequencing solutions, today announced
two new high throughput library preparation kits and workflows
optimized for its Revio sequencing system. With these kits,
PacBio takes another leap forward in the long-read market by
offering customers automated, scalable, and high-performance
library preparation solutions with a 40 percent reduction in costs
and a 60 percent decrease in workflow time. In addition, with the
HiFi Plex Prep Kit 96 now including 384 validated barcode adapters,
customers will have the groundbreaking ability to run 1,536 samples
in a single Revio run.
"With the launch of these new kits, PacBio will bring our
customers scale, savings, and speed never before possible on
Revio," said Jeff Eidel, Chief
Commercial Officer at PacBio. "We are always in conversation with
our customers about future innovation and these kits were built in
response to several large projects recently won on Revio with
customers wanting to scale to thousands if not tens of thousands of
samples per year. We are thrilled with the prospect of providing
customers with meaningful options for scale that allow them to
explore emerging applications."
Engineered for efficiency, the new HiFi Prep Kit 96 and HiFi
Plex Prep Kit 96 are designed to allow users the ability to
automate long-read sequencing workflow steps and streamline the
process of preparing, pooling, and loading samples. These
capabilities help eliminate bottlenecks related to cost, time, and
labor, making them one of the most cost-effective high-throughput
long-read library preparation solutions on the market.
For microbial, metagenome, and low-pass whole genome sequencing
customers, these new offerings will allow them to unlock large
projects with organizations of varying budget requirements. The new
kit configurations will also provide customers with a 4-fold
reduction in waste and packaging as compared to the previous
generation of PacBio library preparation kits.
"The new automated workflow is providing high quality HiFi-GS
libraries in our pilot experiments on human blood DNAs," said Tomi
Pastinen, M.D., Ph.D. Dee
Lyons/Missouri Endowed Chair in Pediatric Genomic Medicine
and Director for the Center for Pediatric Genomic Medicine at
Children's Mercy Kansas City. "We are excited to implement the
workflow in clinical HiFi-GS research to reduce turnaround time and
increase efficiency, respectively."
"The output of Revio opened up the possibility of scaling the
use of long-read sequencing beyond reference genomes into
genotyping," said Josh Clevenger,
Ph.D., Faculty Investigator at HudsonAlpha Institute for
Biotechnology. "The speed and ease of use of the HiFi Prep Kit 96
and HiFi Plex Prep Kit 96 has made it possible for us to use
long-read sequencing as a high-throughput genotyping tool."
The new HiFi library prep kits are expected to be available for
purchase in the first quarter of 2024, with delivery planned early
in the second quarter of 2024. Automated protocols will first be
available on the Hamilton NGS STAR system, with qualified protocols
on additional PacBio Compatible automation platform partners being
added in the future. Kits contain enough volume for customers to
develop their own automated methods.
About PacBio
PacBio (NASDAQ: PACB) is a premier life
science technology company that is designing, developing and
manufacturing advanced sequencing solutions to help scientists and
clinical researchers resolve genetically complex problems. Our
products and technologies stem from two highly differentiated core
technologies focused on accuracy, quality and completeness which
include our HiFi long-read sequencing and our SBB® short-read
sequencing technologies. Our products address solutions across a
broad set of research applications including human germline
sequencing, plant and animal sciences, infectious disease and
microbiology, oncology, and other emerging applications. For more
information, please visit www.pacb.com and follow @PacBio.
PacBio products are provided for Research Use Only. Not for
use in diagnostic procedures.
Forward-Looking Statements
This press release may
contain "forward-looking statements" within the meaning of Section
21E of the Securities Exchange Act of 1934, as amended, and the
U.S. Private Securities Litigation Reform Act of 1995. All
statements other than statements of historical fact are
forward-looking statements, including statements relating to future
availability, uses, advantages, quality or performance of, or
benefits or expected benefits of using, PacBio products or
technologies, including HiFi Prep 96 and HiFi Plex 96 Prep kits;
advancement in the long-read market; reductions in cost and
workflow time; advancements in scale and exploring applications;
automation of workflows; elimination of bottlenecks; streamlining
preparation, pooling, and loading; cost-effectiveness; and
reduction in waste and packaging; among other future events.
Readers are cautioned not to place undue reliance on these
forward-looking statements and any such forward-looking statements
are qualified in their entirety by reference to the following
cautionary statements. All forward-looking statements speak only as
of the date of this press release and are based on current
expectations and involve a number of assumptions, risks and
uncertainties that could cause the actual results to differ
materially from such forward-looking statements. These risks
include, but are not limited to, challenges inherent in developing,
manufacturing, launching, marketing and selling new products;
potential product performance and quality issues and potential
delays in development and commercialization timelines; rapidly
changing technologies and extensive competition in genomic
sequencing that could make the products PacBio is developing
obsolete or non-competitive; and third-party claims alleging
infringement of patents and proprietary rights or seeking to
invalidate PacBio's patents or proprietary rights. Readers are
strongly encouraged to read the full cautionary statements
contained in PacBio's filings with the Securities and Exchange
Commission, including the risks set forth in PacBio's Forms 8-K,
10-K, and 10-Q. PacBio disclaims any obligation to update or revise
any forward-looking statements.
Contacts
Investors:
Todd Friedman
ir@pacificbiosciences.com
Media:
Lizelda Lopez
pr@pacificbiosciences.com
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SOURCE Pacific Biosciences of California, Inc.