- Statement of Changes in Beneficial Ownership (4)

FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES	OMB APPROVAL OMB Number: 3235-0287 Expires: February 28, 2011 Estimated average burden hours per response... 0.5
	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(f) of the Investment Company Act of 1940

1. Name and Address of Reporting Person ^* THIER SAMUEL O MD	2. Issuer Name and Ticker or Trading Symbol CHARLES RIVER LABORATORIES INTERNATIONAL INC [ CRL ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __ X __ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below)
(Last) (First) (Middle) 251 BALLARDVALE STREET	3. Date of Earliest Transaction (MM/DD/YYYY) 2/15/2011
(Street) WILMINGTON, MA 01887 (City) (State) (Zip)	4. If Amendment, Date Original Filed (MM/DD/YYYY)	6. Individual or Joint/Group Filing (Check Applicable Line) _ X _ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	3. Trans. Code (Instr. 8)		4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock	2/15/2011		S		500	D	$37.44	21850	D
Common Stock	2/15/2011		S		700	D	$37.45	21150	D
Common Stock	2/15/2011		S		100	D	$37.455	21050	D
Common Stock	2/15/2011		S		100	D	$37.465	20950	D
Common Stock	2/15/2011		S		208	D	$37.47	20742	D
Common Stock	2/15/2011		S		300	D	$37.475	20442	D
Common Stock	2/15/2011		S		1100	D	$37.48	19342	D
Common Stock	2/15/2011		S		600	D	$37.49	18742	D
Common Stock	2/15/2011		S		200	D	$37.495	18542	D
Common Stock	2/15/2011		S		100	D	$37.4975	18442	D
Common Stock	2/15/2011		S		600	D	$37.50	17842	D
Common Stock	2/15/2011		S		500	D	$37.505	17342	D
Common Stock	2/15/2011		S		200	D	$37.5075	17142	D
Common Stock	2/15/2011		S		500	D	$37.51	16642	D
Common Stock	2/15/2011		S		300	D	$37.515	16342	D
Common Stock	2/15/2011		S		500	D	$37.52	15842	D
Common Stock	2/15/2011		S		200	D	$37.53	15642	D
Common Stock	2/15/2011		S		200	D	$37.535	15442	D
Common Stock	2/15/2011		S		900	D	$37.54	14542	D
Common Stock	2/15/2011		S		100	D	$37.545	14442	D
Common Stock	2/15/2011		S		400	D	$37.55	14042	D
Common Stock	2/15/2011		S		200	D	$37.555	13842	D
Common Stock	2/15/2011		S		200	D	$37.5575	13642	D
Common Stock	2/15/2011		S		332	D	$37.56	13310	D
Common Stock	2/15/2011		S		500	D	$37.58	12810	D
Common Stock	2/15/2011		S		100	D	$37.585	12710	D
Common Stock	2/15/2011		S		100	D	$37.5875	12610	D
Common Stock	2/15/2011		S		400	D	$37.59	12210	D
Common Stock	2/15/2011		S		100	D	$37.595	12110	D
Common Stock	2/15/2011		S		200	D	$37.60	11910	D

*Table II - Derivative Securities Beneficially Owned ( e.g.* , puts, calls, warrants, options, convertible securities)**
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	4. Trans. Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)			11. Nature of Indirect Beneficial Ownership (Instr. 4)

Explanation of Responses:

Reporting Owners
Reporting Owner Name / Address	Relationships
Reporting Owner Name / Address	Director	10% Owner	Officer	Other
THIER SAMUEL O MD 251 BALLARDVALE STREET WILMINGTON, MA 01887	X

Signatures
/s/ Matthew L. Daniel, attorney-in-fact for Samuel O. Thier, MD		2/17/2011
^** Signature of Reporting Person		Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:	File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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