Securities Registration: Employee Benefit Plan (s-8)

As filed with the Securities and Exchange Commission on November 10, 2016 Registration No. 333-____________

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, DC 20549

_________________

FORM S-8

REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

_________________

Lion Biotechnologies, Inc.

(Exact name of registrant as specified in its charter)

_________________

Nevada

(State or other jurisdiction of

incorporation or organization)

75-3254381

(I.R.S. Employer

Identification Number)

999 Skyway Road, Suite 150

San Carlos, California 94070

(Address of registrant’s principal executive offices, including zip code)

_________________________________

Lion Biotechnologies, Inc. 2014 Equity Incentive Plan
(Full title of the plan)

_________________

Maria Fardis, Ph.D.

President and Chief Executive Officer

Lion Biotechnologies, Inc.

999 Skyway Road, Suite 150

San Carlos, California 94070

(650) 260-7120)

(Name, address, including zip code, and telephone number, including area code, of agent for service)

_________________

With copies to:

Istvan Benko

TroyGould PC

1801 Century Park East, 16th Floor

Los Angeles, California 90067

(310) 553-4441

_________________

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act. (Check one):

Large accelerated filer o	Accelerated filer x
Non-accelerated filer o (Do not check if a smaller reporting company)	Smaller reporting company o

_________________

CALCULATION OF REGISTRATION FEE

Title of each class of securities to be registered

Amount to be
registered ⁽¹⁾

Proposed maximum offering price per share

Proposed maximum aggregate offering price

Amount of

registration fee

Common stock, par value $0.000041666 per share

5,000,000 ⁽²⁾

$5.875 ⁽³⁾

$29,375,000

$3,404.56

(1)

Pursuant to Rule 416(a) of the Securities Act of 1933, as amended (the “Securities Act”), this Registration Statement also covers such additional shares of common stock as may become issuable under the plans in the event of a stock split, stock dividend, recapitalization or other similar change in the outstanding shares of common stock.

(2)

Represents shares of common stock reserved for issuance following the grant of future awards under the 2014 Equity Incentive Plan (the “2014 Plan”).

(3)

Estimated solely for the purpose of calculating the registration fee in accordance with Rule 457(c) under the Securities Act, and (h) under the Securities Act based on the average of the high and low sale prices of the common stock as reported on the Nasdaq Global Market on November 4, 2016.

EXPLANATORY NOTE UNDER GENERAL INSTRUCTION E

REGISTRATION OF ADDITIONAL SECURITIES AND INCORPORATION BY REFERENCE

This Registration Statement relates solely to the registration of additional securities of the same class as other securities for which a registration statement on this form relating to an employee benefit plan is effective. A Registration Statement on Form S-8, File No. 333-205097 was filed on June 18, 2015 to register 3,918,000 shares of common stock of Lion Biotechnologies, Inc. (“Registrant”), that were issuable under Registrant’s 2014 Equity Incentive Plan (the “2014 Plan”). At its annual meeting of stockholders held on August 16, 2016, the stockholders of the Registrant approved an amendment to the 2014 Plan to increase the number of shares issuable upon the exercise of options and other awards granted thereunder by 5,000,000 shares. Accordingly, this registration statement registers those additional 5,000,000 shares of common stock issuable under the 2014 Plan.

INCORPORATION BY REFERENCE OF PRIOR REGISTRATION STATEMENT

The contents of the Registration Statement of Registrant, File No. 333-205097, filed on June 18, 2015, as that registration statement may be amended, are incorporated into this Registration Statement by this reference, pursuant to General Instruction E to Form S-8, except that the provisions contained in Part II of such earlier registration statement are modified as set forth in this registration statement.

PART II

INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

ITEM 3.

Incorporation of Documents by Reference

Registrant hereby incorporates by reference the following documents previously filed with the Securities and Exchange Commission (the “Commission”):

our Annual Report on Form 10-K for the year ended December 31, 2015 filed with the SEC on March 11, 2016;

our Quarterly Reports on Form 10-Q for the quarters ended March 31, 2016, June 30, 2016 and September 30, 2016, filed with the SEC on May 9, 2016, August 9, 2016 and November 4, 2016, respectively;

our Current Reports on Form 8-K filed with the SEC on January 4, 2016, March 10, 2016, March 15, 2016, April 7, 2016, May 9, 2016, May 27, 2016, June 3, 2016, June 8, 2016, June 8, 2016, July 8, 2016, August 8, 2016, August 18, 2016, August 24, 2016, September 15, 2016, October 3, 2016, November 3, 2016, and November 4, 2016, respectively; and

the description of our stock contained in our registration statement on Form 8-A filed on February 25, 2015 pursuant to Section 12 of the Exchange Act, as such statement may be amended from time to time.

All documents filed by Registrant pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act subsequent to the date of this Registration Statement and prior to the filing of a post-effective amendment to this Registration Statement which indicates that all securities offered hereby have been sold or which deregisters all such securities then remaining unsold, shall be deemed to be incorporated by reference herein and to be a part hereof from the date of filing of such documents. Any statement contained in this Registration Statement, in an amendment hereto or in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a statement contained herein or in any subsequently filed amendment to this Registration Statement or in any document that is or is deemed to be incorporated by reference herein modifies or supersedes such statement.

Under no circumstances shall any information furnished prior to or subsequent to the date hereof under Item 2.02 or 7.01 of Form 8-K be deemed incorporated herein by reference unless such Form 8-K expressly provides to the contrary.

ITEM 8.

Exhibits

See the Exhibit Index following the signature page for a list of exhibits filed as part of this Registration Statement, which Exhibit Index is incorporated herein by reference.

ITEM 9.

Undertakings

(a) The undersigned Registrant hereby undertakes:

(1) To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:

(i) To include any prospectus required by Section 10(a)(3) of the Securities Act;

(ii) To reflect in the prospectus any facts or events arising after the effective date of this Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in this Registration Statement;

(iii) To include any material information with respect to the plan of distribution not previously disclosed in this Registration Statement or any material change to such information in this Registration Statement; provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in periodic reports filed with or furnished to the Commission by Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that are incorporated by reference in this Registration Statement.

(2) That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

(3) To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.

(b) The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of Registrant’s annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan’s annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in this Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

(h) Insofar as indemnification for liabilities arising under the Securities Act of 1933 may be permitted to directors, officers and controlling persons of the registrant pursuant to the foregoing provisions, or otherwise, the registrant has been advised that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in the Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the registrant of expenses incurred or paid by a director, officer or controlling person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Act and will be governed by the final adjudication of such issue.

SIGNATURES

Pursuant to the requirements of the Securities Act of 1933, Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in San Carlos, California, on November 10, 2016.

	LION BIOTECHNOLOGIES, INC.

	By:	/s/ Maria Fardis
		Maria Fardis
		President and Chief Executive Officer

POWER OF ATTORNEY

KNOW ALL PERSONS BY THESE PRESENTS, that each individual whose signature appears below constitutes and appoints Maria Fardis and Gregory T. Schiffman, and each of them, his/her true and lawful attorneys-in-fact and agents with full power of substitution and re-substitution, for him/her and in his/her name, place and stead, in any and all capacities, to sign any and all amendments, including post-effective amendments, to this Registration Statement, and to sign any registration statement for the same offering covered by this Registration Statement and filed pursuant to Rule 462 under the Securities Act of 1933, as amended, and to file the same, with all exhibits thereto and all documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents or any of them, or her or his or their substitute or substitutes, may lawfully do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Act of 1933, as amended, this Registration Statement has been signed by the following persons in the capacities indicated.

Signature	Title	Date

/s/ Maria Fardis	Chief Executive Officer and Director (Principal Executive Officer)	November 10, 2016
Maria Fardis, Ph.D.

/s/ Gregory T. Schiffman	Chief Financial Officer (Principal Financial and Accounting Officer)	November 10, 2016
Gregory T. Schiffman

/s/ Merrill A. McPeak	Director	November 10, 2016
Merrill A. McPeak	Director

/s/ Jay Venkatesan	Director	November 10, 2016
Jay Venkatesan	Director

/s/ Sanford J. Hillsberg	Director	November 10, 2016
Sanford J. Hillsberg

/s/ Wayne Rothbaum	Director	November 10, 2016
Wayne Rothbaum

/s/ Ryan Maynard	Director	November 10, 2016
Ryan Maynard	Director

/s/ Iain Dukes	Director	November 10, 2016
Iain Dukes

EXHIBIT INDEX

Exhibit No.		Description

4.1		Amended and Restated Articles of Incorporation of Registrant (incorporated herein by reference to Registrant’s definitive Information Statement on Schedule 14C filed with the Commission on August 20, 2013).

4.2		Bylaws of Registrant (incorporated herein by reference to the Registrant’s Registration Statement on Form SB-2 (Reg. No. 333-148920) filed with the Commission on January 29, 2008).

4.3		Amendment to Bylaws (incorporated herein by reference to the Registrant’s Current Report on Form 8-K filed with the Commission on May 29, 2013).

4.4		Specimen Common Stock Certificate of Registrant (incorporated herein by reference to Registrant’s registration statement on Form 8-A filed on February 25, 2015).

4.5		Lion Biotechnologies, Inc. 2014 Equity Incentive Plan, as amended (incorporated herein by reference to Appendix A to Registrant’s definitive Proxy Statement on Schedule 14A filed with the Commission on July 7, 2016).

4.6		Form of ISO Stock Option Agreement under 2014 Equity Incentive Plan (incorporated herein by reference to Registrant’s registration statement on Form S-8 , File No. 333-205097, filed on June 18, 2015 ).

4.7		Form of NQSO Stock Option Agreement under 2014 Equity Incentive Plan (incorporated herein by reference to Registrant’s registration statement on Form S-8 , File No. 333-205097, filed on June 18, 2015 ).

5.1		Opinion of TroyGould PC

23.1		Consent of TroyGould PC (included in Exhibit 5.1)

23.2		Consent of Weinberg & Company

24.1		Power of Attorney (included on the signature page herein)