UPDATE - Passage Bio to Present Updated Imagine-1 Study Clinical and Biomarker Data at the American Society of Gene and Cell Therapy 25th Annual Meeting
May 03 2022 - 2:13PM
Passage Bio, Inc. (NASDAQ: PASG), a clinical-stage genetic
medicines company focused on developing transformative therapies
for central nervous system (CNS) disorders, today announced that
additional clinical and biomarker data from Cohort 1 in the
Imagine-1 study for GM1 gangliosidosis will be presented at the
upcoming American Society of Gene and Cell Therapy (ASGCT) 25th
Annual Meeting, which is being held in Washington, D.C. and
virtually on May 16-19, 2022.
Late-breaker oral presentation details:
Title: Interim Safety, Biomarker, and Efficacy
Data From Imagine-1: A Phase 1/2 Open-label, Multicenter Study to
Assess the Safety, Tolerability, and Efficacy of a Single Dose, ICM
Administration of PBGM01 in Subjects with Type I (Early Onset) and
Type IIa (Late Onset) Infantile GM1 Gangliosidosis
(GM1)Date/Time: Wednesday, May 18, 2022 from 8:30
a.m. to 8:45 a.m. ETPresenter: David Weinstein,
M.D. M.M.Sc.Abstract Number: 2257
Additionally, scientists from the University of Pennsylvania’s
Gene Therapy Program (GTP) will present several abstracts
containing data supporting earlier-stage Passage Bio programs and
ongoing discovery research. This includes a poster presentation on
preclinical data supporting Passage Bio’s study of PBML04 for
metachromatic leukodystrophy (MLD).
Title: Long-term evaluation of the efficacy of
intracerebroventricularly injected AAVhu68 encoding human codon
optimized ARSA (hARSA) transgene in a mouse model of Metachromatic
leukodystrophy (MLD)Date/Time: Wednesday, May 18,
2022 from 5:30 p.m. to 6:30 p.m. ETPresenter:
Gourav Roy Choudhury, Ph.D.Abstract Number:
1024
About Passage BioAt Passage Bio (Nasdaq: PASG),
we are on a mission to provide life-transforming genetic medicines
for patients with CNS diseases that replace their suffering with
boundless possibility, all while building lasting relationships
with the communities we serve. Based in Philadelphia, PA, our
company has established a strategic collaboration and licensing
agreement with the renowned University of Pennsylvania’s Gene
Therapy Program to conduct our discovery and IND-enabling
preclinical work. This provides our team with enhanced access to a
broad portfolio of gene therapy candidates and future gene therapy
innovations that we then pair with our deep clinical, regulatory,
manufacturing and commercial expertise to rapidly advance our
robust pipeline of optimized gene therapies into clinical testing.
As we work with speed and tenacity, we are always mindful of
patients who may be able to benefit from our therapies. More
information is available at www.passagebio.com.
Penn Financial DisclosureDr. James Wilson,
director of the Gene Therapy Program, is a Penn faculty member as
well as a scientific collaborator, consultant, and co-founder of
Passage Bio. As such, he holds an equity stake in the company,
receives sponsored research funding from Passage Bio, and as an
inventor of certain Penn intellectual property that is licensed to
Passage Bio, may receive additional financial benefits in the
future. The University of Pennsylvania also receives sponsored
research funding from Passage Bio and has licensed intellectual
property to the company that may result in future financial returns
to Penn.
For further information, please contact:
Passage Bio Investors:Stuart HendersonPassage
Bio267.866.0114shenderson@passagebio.com
Passage Bio Media:Mike BeyerSam Brown Inc.
Healthcare Communications312-961-2502MikeBeyer@sambrown.com
Passage Bio (NASDAQ:PASG)
Historical Stock Chart
From Mar 2024 to Apr 2024
Passage Bio (NASDAQ:PASG)
Historical Stock Chart
From Apr 2023 to Apr 2024