ContraFect Invited to Participate in the Cystic Fibrosis Target Product Profile Virtual Symposium
April 26 2021 - 7:30AM
ContraFect Corporation (Nasdaq: CFRX), a late clinical-stage
biotechnology company focused on the discovery and development of
direct lytic agents (DLAs), including lysins and amurin peptides,
as new medical modalities for the treatment of life-threatening,
antibiotic-resistant infections, today announced that Cara Cassino,
MD, Chief Medical Officer and Executive Vice President of Research,
will participate in the Cystic Fibrosis (CF) Target Product Profile
(TPP) Virtual Symposium on April 30th, 2021. The symposium has been
established by the CF Syndicate in Antimicrobial Resistance (AMR)
and is supported by the Cystic Fibrosis Trust and The Medicines
Discovery Catapult, both United Kingdom based organizations
fostering cutting edge therapeutic research. The purpose of the
symposium is to convene expertise in CF infections, including CF
patients and clinicians, pharmaceutical and biotech executives and
other key stakeholders, to provide patient-focused feedback and
insight on potential product profiles for new antimicrobial agents
to address the challenge of AMR in CF infections, including
pulmonary exacerbations.
“We are excited to participate in an event whose
aim is to guide and catalyze antimicrobial development to the
benefit of CF patients,” said Dr. Cassino. “Our internal discovery
of proprietary DLAs, such as CF-370, our engineered lysin targeting
Pseudomonas aeruginosa, and our amurin peptides, which target a
broad spectrum of Gram-negative pathogens, are being developed with
the potential to demonstrate superior clinical outcomes for
serious, life-threatening infections like those experienced by
patients living with CF.”
About ContraFect
ContraFect is a biotechnology company focused on
the discovery and development of DLAs, including lysins and amurin
peptides, as new medical modalities for the treatment of
life-threatening, antibiotic-resistant infections. An estimated
700,000 deaths worldwide each year are attributed to
antimicrobial-resistant infections. We intend to address life
threatening infections using our therapeutic product candidates
from our platform of DLAs, which include lysins and amurin
peptides. Lysins are a new class of DLAs which are recombinantly
produced antimicrobial proteins with a novel mechanism of action
associated with the rapid killing of target bacteria, eradication
of biofilms and synergy with conventional antibiotics. Amurin
peptides are a novel class of DLAs which exhibit broad-spectrum
activity against a wide range of antibiotic-resistant Gram-negative
pathogens, including Pseudomonas aeruginosa, Acinetobacter
baumannii, and Enterobacter species. We believe that the properties
of our lysins and amurin peptides will make them suitable for
targeting antibiotic-resistant organisms, such as MRSA and P.
aeruginosa, which can cause serious infections such as bacteremia,
pneumonia and osteomyelitis. We have completed a Phase 2 clinical
trial for the treatment of Staph aureus bacteremia, including
endocarditis, with our lead lysin candidate, exebacase, which is
the first lysin to enter clinical studies in the U.S. Exebacase,
currently being studied in a pivotal Phase 3 clinical study, was
granted Breakthrough Therapy designation by the FDA for the
treatment of MRSA bloodstream infections, including right-sided
endocarditis, when used in addition to SOC anti-staphylococcal
antibiotics in adult patients.
Follow ContraFect on Twitter @ContraFectCorp and LinkedIn.
Forward-Looking Statements
This press release contains, and our officers
and representatives may make from time to time, “forward-looking
statements” within the meaning of the U.S. federal securities laws.
Forward-looking statements can be identified by words such as
“projects,” “may,” “will,” “could,” “would,” “should,” “believes,”
“expects,” “anticipates,” “estimates,” “intends,” “plans,”
“potential,” “promise” or similar references to future periods.
Examples of forward-looking statements in this release include,
without limitation, statements regarding: the symposium,
ContraFect’s ability to discover and develop DLAs as new medical
modalities for the treatment of life-threatening,
antibiotic-resistant infections, whether ContraFect will address
life-threatening infections using its DLA platform, whether lysins
are a new class of DLAs which are recombinantly produced,
antimicrobial proteins with a novel mechanism of action associated
with the rapid killing of target bacteria, eradication of biofilms
and synergy with conventional antibiotics, whether amurins are a
novel class of DLAs which exhibit broad-spectrum activity against a
wide range of antibiotic-resistant Gram-negative pathogens, and
whether the properties of ContraFect’s lysins and amurins will make
them suitable for targeting antibiotic-resistant organisms, such as
MRSA and P. aeruginosa. Forward-looking statements are statements
that are not historical facts, nor assurances of future
performance. Instead, they are based on ContraFect’s current
beliefs, expectations and assumptions regarding the future of its
business, future plans, strategies, projections, anticipated events
and trends, the economy and other future conditions. Because
forward-looking statements relate to the future, they are subject
to inherent risks, uncertainties and changes in circumstances that
are difficult to predict and many of which are beyond ContraFect’s
control, including the occurrence of any adverse events related to
the discovery, development and commercialization of ContraFect’s
product candidates such as unfavorable clinical trial results,
insufficient supplies of drug products, the lack of regulatory
approval, or the unsuccessful attainment or maintenance of patent
protection and other important risks detailed under the caption
“Risk Factors” in ContraFect's filings with the Securities and
Exchange Commission. Actual results may differ from those set forth
in the forward-looking statements. Important factors that could
cause actual results to differ include, among others, our ability
to develop treatments for drug-resistant infectious diseases. Any
forward-looking statement made by ContraFect in this press release
is based only on information currently available and speaks only as
of the date on which it is made. Except as required by applicable
law, ContraFect expressly disclaims any obligations to publicly
update any forward-looking statements, whether written or oral,
that may be made from time to time, whether as a result of new
information, future developments or otherwise.
Investor Relations Contacts
Michael MessingerContraFect
Corporationmmessinger@contrafect.com
Carlo Tanzi, Ph.D.Kendall Investor
Relationsctanzi@kendallinvestorrelations.com
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