FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Schuler Henri George 		2. Issuer Name and Ticker or Trading Symbol

VERMILLION, INC. [ VRML ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      __ X __ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

100 N. FIELD DRIVE, SUITE 360 		3. Date of Earliest Transaction (MM/DD/YYYY)

8/31/2017
(Street)

LAKE FOREST, IL 60045
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, par value $0.001   8/31/2017     X    571702   A $1   2897021   I   By Tino Hans Schuler Trust   (1) (7)
Common Stock, par value $0.001   8/31/2017     X    571702   A $1   2897021   I   By Tanya Eva Schuler Trust   (2) (7)
Common Stock, par value $0.001   8/31/2017     X    571702   A $1   2897021   I   By Therese Heidi Schuler Trust   (3) (7)
Common Stock, par value $0.001   8/31/2017     X    113332   A $1   840003   I   By Schuler GC 2010 Continuation Trust   (4) (7)
Common Stock, par value $0.001   8/31/2017     X    113332   A $1   353240   I   By Schuler Grandchildren LLC   (5) (7)
Common Stock, par value $0.001                  141304   I   By Seascape Partners L.P.   (6) (7)
Common Stock, par value $0.001                  26000   I   By spouse   (7)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Warrants (Right to Buy)   $1   8/31/2017     X         571702    8/25/2017   8/31/2017   Common Stock   571702   $0   0   I   By Tino Hans Schuler Trust   (1) (7)
Warrants (Right to Buy)   $1   8/31/2017     X         571702    8/25/2017   8/31/2017   Common Stock   571702   $0   0   I   By Tanya Eva Schuler Trust   (2) (7)
Warrants (Right to Buy)   $1   8/31/2017     X         571702    8/25/2017   8/31/2017   Common Stock   571702   $0   0   I   By Therese Heidi Schuler Trust   (3) (7)
Warrants (Right to Buy)   $1   8/31/2017     X         113332    8/25/2017   8/31/2017   Common Stock   113332   $0   0   I   By Schuler GC 2010 Continuation Trust   (4) (7)
Warrants (Right to Buy)   $1   8/31/2017     X         113332    8/25/2017   8/31/2017   Common Stock   113332   $0   0   I   By Schuler Grandchildren LLC   (5) (7)
Warrants (Right to Buy)   $1.8                    8/17/2017   2/17/2022   Common Stock   365072     365072   I   By Tino Hans Schuler Trust   (1) (7)
Warrants (Right to Buy)   $1.8                    8/17/2017   2/17/2022   Common Stock   365072     365072   I   By Tanya Eva Schuler Trust   (2) (7)
Warrants (Right to Buy)   $1.8                    8/17/2017   2/17/2022   Common Stock   365072     365072   I   By Therese Heidi Schuler Trust   (3) (7)
Warrants (Right to Buy)   $1.8                    8/17/2017   2/17/2022   Common Stock   365072     365072   I   By Schuler GC 2010 Continuation Trust   (4) (7)

Explanation of Responses:
(1)  These Shares of Common Stock ("Shares") and Warrants to acquire Common Stock ("Warrants") are directly owned by the Tino Hans Schuler Trust. H. George Schuler is the sole trustee of the Tino Hans Schuler Trust.
(2)  These Shares and Warrants are directly owned by the Tanya Eva Schuler Trust. H. George Schuler is the sole trustee of the Tanya Eva Schuler Trust.
(3)  These Shares and Warrants are directly owned by the Therese Heidi Schuler Trust. H. George Schuler is the sole trustee of the Therese Heidi Schuler Trust.
(4)  These Shares and Warrants are directly owned by the Schuler GC 2010 Continuation Trust. H. George Schuler is the sole trustee of the Schuler GC 2010 Continuation Trust.
(5)  These Shares are directly owned by the Schuler Grandchildren LLC. H. George Schuler is the manager of the Schuler Grandchildren LLC.
(6)  These Shares are directly owned by Seascape Partners L.P., a family limited partnership. H. George Schuler is the manager of Seascape Partners L.P.
(7)  The reporting person disclaims beneficial ownership of these Shares except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Schuler Henri George
100 N. FIELD DRIVE
SUITE 360
LAKE FOREST, IL 60045
X


Signatures
/s/ H. George Schuler 9/5/2017
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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