- Withdrawal of Registration Statement (RW)

Arno Therapeutics, Inc.

4 Campus Drive, 2 nd Floor

Parsippany, NJ 07054

(862) 703-7170

May 1, 2009

VIA EDGAR

U.S. Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549

Attention: Mr. Jeffrey Riedler


	Re:	Arno Therapeutics, Inc. (the “Company”)
		Request for Withdrawal of Post-Effective Amendment No. 1 to Form S-1
		File No. 333-152660

Dear Mr. Riedler:

On behalf of the Company, the undersigned respectfully requests withdrawal of the above-referenced Post-Effective Amendment No. 1 to Form S-1 that was filed with the Securities and Exchange Commission on April 14, 2009 (the “Post-Effective Amendment”).

In accordance with Rule 477 promulgated pursuant to the Securities Act of 1933, as amended, the undersigned confirms that no securities of the Company were sold pursuant to the Post-Effective Amendment. Effectiveness of the Post-Effective Amendment has not been granted. The grounds on which the Company makes this application are that there is no longer any intention to offer or sell securities under the Post-Effective Amendment.