CHICAGO, July 29, 2011 /PRNewswire/ -- Zacks Equity Research highlights Fastenal Co. (Nasdaq: FAST) as the Bull of the Day and Morgan Stanley (NYSE: MS) as the Bear of the Day. In addition, Zacks Equity Research provides analysis The Medicines Company (Nasdaq: MDCO), Biogen Idec Inc. (Nasdaq: BIIB) and Pfizer (NYSE: PFE).

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Full analysis of all these stocks is available at http://at.zacks.com/?id=2678.

Here is a synopsis of all five stocks:

Bull of the Day:

Fastenal Co. (Nasdaq: FAST) is one of the leading distributors of industrial and construction supplies and fasteners. It has a diversified customer base that helps it retain its market position even during the toughest times. Moreover, the hub and spoke model employed to improve the level of customer services will also increase customer satisfaction and benefit its business going forward.

In addition, Fastenal is focused on expanding its product portfolio. Furthermore, the company's collaborative efforts to work with state governments will strengthen its position in the local market.

Earnings in the most recent quarter marginally exceeded the Zacks Consensus Estimate by $0.01 per share. Given these conditions, we have upgraded our recommendation on shares of Fastenal to Outperform from Neutral and set a target price of $41.

Bear of the Day:

We are downgrading our recommendation on Morgan Stanley (NYSE: MS) to Underperform on its weak second quarter results, lower possibility of capital deployment and the expected adverse impact of regulatory restrictions. The MUFG preferred stock conversion resulted in a substantial loss during the quarter, though it enhanced the company's capital cushion.

Moreover, higher interest and non-interest expenses were among the negatives in the earnings report. There are also concerns related to the company's financials being marred by new regulatory restrictions and intense pricing competition.

Our six-month target price of $20.00 equates to about 17.7x our earnings estimate for 2011. Combined with the $0.20 per share annual dividend, this price target implies an expected negative total return of 10.8% over that period, which is consistent with our Underperform recommendation.

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Medicines Co. Profits Down

The Medicines Company (Nasdaq: MDCO) reported second-quarter earnings of 18 cents per share, including the impact of stock-based compensation expense. Second-quarter earnings were well below the year-ago earnings of 31 cents. The Zacks Consensus Estimate for the second quarter of 2011 was 20 cents.

Despite an increase in revenues, higher expenses led to the decline in earnings. Revenues, up 8.6% at $119.6 million, were just above the Zacks Consensus Estimate of $118 million.

The Quarter in Detail

Angiomax US sales increased 7% to $112 million during the second quarter. Ex-US sales increased 27% to $7.3 million.

The National Institute for Health and Clinical Excellence (NICE) in the UK recently announced that Angiox (ex-US trade name of Angiomax) is economically dominant (less costly and more effective than currently available therapies) for heart attack patients. This should help increase Angiox' share in the UK market.

Moreover, Angiox ("Angiomax" trade name in Europe) has a Class I recommendation from the European Society of Cardiology for heart attack patients undergoing percutaneous coronary intervention (PCI).

Angiomax, acquired from Biogen Idec Inc. (Nasdaq: BIIB), is the lead product at The Medicines Company. Acquired in 1996, Angiomax is used as an anticoagulant in patients undergoing coronary angioplasty.

Meanwhile, Cleviprex (clevidipine) is the only other FDA-approved drug at The Medicines Company. The company had initiated a voluntary recall of Cleviprex in December 2009 due to the presence of visible particulate matter in some vials.

The Medicines Company has resumed shipping Cleviprex to select customers. The first phase involves shipment to 100 leading hospitals with the full re-launch scheduled to take place in the second half of 2011.

Going forward, The Medicines Company intends to focus on neuro critical care and surgical procedures in the cardiac area where blood pressure control is very critical. The company has also been working on a new formulation of Cleviprex and expects a regulatory update on the same in the third quarter of 2011.

R&D spend increased 28.9% to $26.5 million mainly due to ongoing phase III studies with two candidates -- Cangrelor and oritavancin. SG&A expenses increased 5.1% to $41.4 million.

Backs Guidance

The Medicines Company maintained its guidance for 2011. The company expects revenues to grow 6-9% in 2011.

Pipeline Update

The Medicines Company also provided an update on its pipeline candidates. The company continued enrolling patients for its phase III studies with Cangrelor and oritavancin. Results from the BRIDGE study being conducted with Cangrelor should be available by year end.

Oritavancin is in a phase III program, SOLO, for the treatment of acute bacterial skin and skin structure infections (ABSSI). Results will be out in 2012. Positive results would allow The Medicines Company to file for US approval in 2012.

Meanwhile, The Medicines Company is hoping to gain approval for its ready-to-use formulation of Argatroban in the third quarter of 2011.

The Medicines Company's early-stage candidates include MDCO-216 and MDCO-2010. The company acquired worldwide rights to MDCO-216 from Pfizer (NYSE: PFE).

MDCO-216 is a naturally occurring variant of a protein that could be used to reverse the development of arterial plaque development and reduce the risk of heart problems in patients with acute coronary syndrome (ACS).

If developed successfully, MDCO-216 should fit well within The Medicines Company's product portfolio. Phase I studies with the candidate are scheduled to commence later this year.

Get the full analysis of all these stocks by going to http://at.zacks.com/?id=2649.

About the Bull and Bear of the Day

Every day, the analysts at Zacks Equity Research select two stocks that are likely to outperform (Bull) or underperform (Bear) the markets over the next 3-6 months.

About the Analyst Blog

Updated throughout every trading day, the Analyst Blog provides analysis from Zacks Equity Research about the latest news and events impacting stocks and the financial markets.

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Continuous analyst coverage is provided for a universe of 1,150 publicly traded stocks. Our analysts are organized by industry which gives them keen insights to developments that affect company profits and stock performance. Recommendations and target prices are six-month time horizons.

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