UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

SCHEDULE 14A
Proxy Statement Pursuant to Section 14(a) of the Securities
Exchange Act of 1934

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¨ Preliminary Proxy Statement
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Pernix Therapeutics Holdings, Inc.
__________________________________________________________________________
(Name of Registrant as Specified In Its Charter)

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

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**** OUR ANNUAL MEETING IS QUICKLY APPROACHING****

****YOUR IMMEDIATE ATTENTION IS REQUESTED ****

May 11, 2018

Dear Pernix Therapeutics Holdings, Inc. Stockholder:

The 2018 Annual Meeting of Stockholders is soon approaching and is scheduled for May 22, 2018 at 9:30 a.m., local time at the Hyatt Morristown at Headquarters Plaza in Morristown, New Jersey.

We are sending this reminder notice because according to your brokers' records your shares are still unvoted. Please see the enclosed voting instruction form and take a few minutes to vote.

Regardless of the number of shares you own, your vote is very important. Because time is short before the Annual Meeting, we urge you promptly to submit your vote by internet or telephone. Please follow the enclosed instructions.

If you have any questions or need assistance voting your shares, please contact our proxy solicitor, Saratoga Proxy Consulting at (888) 368-0379 or (212) 257-1311.

Thank you for your support

 

Pernix Therapeutics Holdings, Inc.