FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

GIANAKAKOS ANASTASIOS
2. Issuer Name and Ticker or Trading Symbol

MyoKardia, Inc. [ MYOK ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
President and CEO
(Last)          (First)          (Middle)

C/O MYOKARDIA, INC., 1000 SIERRA POINT PARKWAY
3. Date of Earliest Transaction (MM/DD/YYYY)

5/11/2020
(Street)

BRISBANE, CA 94005
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 5/11/2020  S(1)  600 D$98.6883 (2)63522 (3)D  
Common Stock 5/11/2020  S(1)  1700 D$100.5056 (4)61822 D  
Common Stock 5/11/2020  S(1)  18581 D$101.9044 (5)43241 D  
Common Stock 5/11/2020  S(1)  3519 D$102.5635 (6)39722 D  
Common Stock 5/11/2020  S(1)  600 D$103.33 (7)39122 D  
Common Stock         129407 I By Reporting Person's Trust 2 (8)
Common Stock         300000 I By Reporting Person's Trust 4 
Common Stock         7000 (9)I By Reporting Person's Trust 5 
Common Stock         10000 (10)I By Reporting Person's Trust 6 
Common Stock         53087 I By Trust 1 
Common Stock         53087 I By Trust 2 
Common Stock         53087 I By Trust 3 

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares

Explanation of Responses:
(1) This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.
(2) Represents the weighted average sale price of the shares sold ranging from $98.50 to $99.46 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the ranges reported in this footnote and footnotes 4 through 7.
(3) Excludes 10,000 shares previously owned directly which were contributed on May 6, 2020 to the MJA Legacy Trust, of which the Reporting Person's children are beneficiaries.
(4) Represents the weighted average price of the shares sold ranging from $100.01 to $100.94 per share.
(5) Represents the weighted average price of the shares sold ranging from $101.07 to $102.05 per share.
(6) Represents the weighted average price of the shares sold ranging from $102.11 to $103.09 per share.
(7) Represents the weighted average price of the shares sold ranging from $103.19 to $103.54 per share.
(8) Excludes 1,000 shares previously held by The TKG Trust dated November 2, 2006 which were redistributed back to the Reporting Person directly and immediately transferred to The TKG 2020 Irrevocable Trust on May 5, 2020.
(9) Includes 1,000 shares previously held by The TKG Trust dated November 2, 2006 which were redistributed back to the Reporting Person directly and immediately transferred to The TKG 2020 Irrevocable Trust on May 5, 2020.
(10) Includes 10,000 shares previously owned directly which were contributed on May 6, 2020 to the MJA Legacy Trust, of which the Reporting Person's children are beneficiaries.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
GIANAKAKOS ANASTASIOS
C/O MYOKARDIA, INC.
1000 SIERRA POINT PARKWAY
BRISBANE, CA 94005
X
President and CEO

Signatures
/s/ Cynthia Ladd, as Attorney-in-Fact5/13/2020
**Signature of Reporting PersonDate

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