FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Proniuk Stefan 		2. Issuer Name and Ticker or Trading Symbol

Arno Therapeutics, Inc [ ARNI ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      _____ 10% Owner
__ X __ Officer (give title below)      _____ Other (specify below)
Chief Development Officer
(Last)          (First)          (Middle)

200 ROUTE 31 NORTH, SUITE 104 		3. Date of Earliest Transaction (MM/DD/YYYY)

4/7/2016
(Street)

FLEMINGTON, NJ 08822
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock                  10047   D  
 

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy)   $2.40                      (1) 6/20/2021   Common Stock   17187     17187   D  
 
Stock Option (right to buy)   $2.40                      (1) 6/20/2021   Common Stock   7191     7191   D  
 
Stock Option (right to buy)   $2.40                      (1) 9/19/2021   Common Stock   10000     10000   D  
 
Stock Option (right to buy)   $2.40                      (1) 1/14/2023   Common Stock   6875     6875   D  
 
Stock Option (right to buy)   $2.40                      (1) 1/14/2023   Common Stock   2291     2291   D  
 
Stock Option (right to buy)   $2.40                      (2) 11/4/2023   Common Stock   45701     45701   D  
 
Stock Option (right to buy)   $2.90                      (3) 1/24/2024   Common Stock   171877     171877   D  
 
Stock Option (right to buy)   $.37   4/7/2016     A      554685         (4) 4/7/2026   Common Stock   554685   $0   554685   D  
 
2012 Series A Warrants (right to buy)   $1.36   (5)                  11/26/2012   11/26/2017   Common Stock   24508   (5)   24508   (5) D  
 

Explanation of Responses:
( 1)  Currently exercisable.
( 2)  Vests in equal 36-monthly installments commencing 12/4/13.
( 3)  Vests 25% on first anniversary date and thereafter will vest in 24 equal monthly installments.
( 4)  Vests one-third on the first anniversary of grant and thereafter in 24 equal monthly installments.
( 5)  As a result of the Issuer's 1/12/16 private placement of common stock at $0.35/share, the exercise price and number of shares subject to the 2012 Series A Warrants were automatically adjusted to the exercise price and shares reflected, pursuant to anti-dilution adjustment provisions.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Proniuk Stefan
200 ROUTE 31 NORTH
SUITE 104
FLEMINGTON, NJ 08822

Chief Development Officer

Signatures
/s/ Christopher J. Melsha as Attorney-in-Fact for Stefan Proniuk, Ph.D. pursuant to Power of Attorney previously filed. 4/11/2016
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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