FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

VAN DEN BOOM DIRK 		2. Issuer Name and Ticker or Trading Symbol

SEQUENOM INC [ SQNM ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                      _____ 10% Owner
__ X __ Officer (give title below)      _____ Other (specify below)
President & CEO
(Last)          (First)          (Middle)

3595 JOHN HOPKINS COURT 		3. Date of Earliest Transaction (MM/DD/YYYY)

12/9/2015
(Street)

SAN DIEGO, CA 92121
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   12/10/2015     A    9375   A $0.00   70544   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Restricted Stock Unit     (1) 12/10/2015     D         9375      (2)   (2) Common Stock   9375   $0.00   9375   D    
Restricted Stock Unit     (1) 12/9/2015     A      751880         (3)   (3) Common Stock   751880   $0.00   751880   D    
Incentive Stock option (right to buy)   $1.33   12/9/2015     A      959167         (4) 12/8/2025   Common Stock   959167   $0.00   959167   D    

Explanation of Responses:
( 1)  Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock.
( 2)  The shares subject to the restricted stock units began vesting in 4 equal annual installments commencing on 12/10/12, such that the shares subject to the restricted stock units are fully vested on 12/10/16.
( 3)  The Shares subject to the restricted stock units vest in 4 equal annual installments commencing on 12/10/15, such that the shares subject to the restricted stock units are fully vested on 12/10/19.
( 4)  The shares subject to the options shall vest in 48 equal monthly installments commencing on 12/10/15, such that the shares subject to the option are fully vested on 12/10/19; provided that the option will not become exercisable unless the closing sales price of the Company's common stock is a minimum of a 25% premium to the exercise price of the option for at least 30 consecutive trading days.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
VAN DEN BOOM DIRK
3595 JOHN HOPKINS COURT
SAN DIEGO, CA 92121 		X
President & CEO

Signatures
/s/ Jeffrey D. Linton, as attorney-in-fact For: Dirk van den Boom 12/11/2015
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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