FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Savel Robert Michael II
2. Issuer Name and Ticker or Trading Symbol

OTONOMY, INC. [ OTIC ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
Chief Technical Officer
(Last)          (First)          (Middle)

C/O OTONOMY, INC., 4796 EXECUTIVE DRIVE
3. Date of Earliest Transaction (MM/DD/YYYY)

1/15/2020
(Street)

SAN DIEGO, CA 92121
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock         16434 (1)D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (right to buy) $3.54 1/15/2020  A   250000     (2)1/14/2030 Common Stock 250000 $0.00 250000 (3)D  

Explanation of Responses:
(1) The shares reported in Table I include an aggregate of 15,178 shares acquired by the Reporting Person since December 1, 2015 pursuant to the Issuer's Employee Stock Purchase Plan.
(2) One-fourth (1/4) of the shares subject to the option vest on January 15, 2021 and one forty-eighth (1/48) of the shares vest monthly thereafter.
(3) In addition to the options acquired as set forth in Table II, the Reporting Person currently holds options to purchase up to an aggregate of 567,040 shares of common stock, which options vest according to their terms.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Savel Robert Michael II
C/O OTONOMY, INC.
4796 EXECUTIVE DRIVE
SAN DIEGO, CA 92121


Chief Technical Officer

Signatures
/s/ Paul E. Cayer, by power of attorney1/17/2020
**Signature of Reporting PersonDate

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