FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public
Utility Holding Company Act of 1935 or Section 30(f) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

HIGHLAND CAPITAL MANAGEMENT LP 		2. Issuer Name and Ticker or Trading Symbol

NEUROBIOLOGICAL TECHNOLOGIES INC /CA/ [ NTII ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      __ X __ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

13455 NOEL ROAD, SUITE 800 		3. Date of Earliest Transaction (MM/DD/YYYY)

11/27/2007
(Street)

DALLAS, TX 75240
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

___ Form filed by One Reporting Person
_ X _ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, $0.001 par value   11/27/2007     P    116303   A $2.7   4080654   (1) (2) I   See Footnote   (3) (4)
Common Stock, $0.001 par value   11/28/2007     P    336000   A $2.71   4416654   (1) (2) I   See Footnote   (3) (4)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Explanation of Responses:
( 1)  This statement is filed by and on behalf of each of the following persons (collectively, the "Reporting Persons"): (i) Highland Capital Management L.P. ("Highland Capital"); (ii) Strand Advisors, Inc. ("Strand"); and (iii) James D. Dondero ("Dondero").
( 2)  Highland Capital is acting as investment adviser and/or manager to other persons, including Highland Multi-Strategy Onshore Master SubFund, L.L.C. ("Multi-Strategy SubFund"); it may be deemed to beneficially own shares owned and/or held by and/or for the account of and/or for the benefit of other persons, including Multi-Strategy SubFund. Strand is the general partner of Highland Capital; it may be deemed to beneficially own shares owned and/or held by and/or for the account of and/or for the benefit of Highland Capital. Dondero is the President and a director of Strand; he may be deemed to beneficially own shares owned and/or held by and/or for the account of and/or for the benefit of Strand.
( 3)  Each of the Reporting Persons declares that neither the filing of this statement nor anything herein shall be construed as an admission that such person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, the beneficial owner of any securities covered by this statement.
( 4)  Each of the Reporting Persons may be deemed to be a member of a group with respect to the issuer or securities of the issuer for the purposes of Section 13(d) or 13(g) of the Act. Each of the Reporting Persons declares that neither the filing of this statement nor anything herein shall be construed as an admission that such person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, (i) acting (or has agreed or is agreeing to act together with any other person) as a partnership, limited partnership, syndicate, or other group for the purpose of acquiring, holding, or disposing of securities of the issuer or otherwise with respect to the issuer or any securities of the issuer or (ii) a member of any group with respect to the issuer or any securities of the issuer.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
HIGHLAND CAPITAL MANAGEMENT LP
13455 NOEL ROAD
SUITE 800
DALLAS, TX 75240
X

DONDERO JAMES D
13455 NOEL ROAD
SUITE 800
DALLAS, TX 75240
X

Strand Advisors, Inc.
13455 NOEL ROAD
SUITE 800
DALLAS, TX 75240
X


Signatures
Highland Capital Management, L.P. By: Strand Advisors, Inc., its general partner /s/ James D. Dondero, President 11/29/2007
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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