Kite Pharma, Inc. (Kite) (Nasdaq:KITE) today announced upcoming
presentations related to KTE-C19, Kite's lead product candidate,
that will take place at the 57th ASH Annual Meeting in Orlando,
Florida, December 5-8, 2015. KTE-C19 is an investigational therapy
in which a patient's T cells are genetically engineered to express
a chimeric antigen receptor (CAR) designed to target the antigen
CD19, a protein expressed on the cell surface of B-cell lymphomas
and leukemias. Kite recently announced that the ZUMA-1 trial
transitioned to the pivotal Phase 2 trial.
"We are encouraged by the preliminary findings seen in Phase 1
of our first company-sponsored trial and look forward to presenting
the data in a peer-reviewed setting," said Dr. Arie Belldegrun,
M.D., FACS, Chairman, President and Chief Executive Officer of
Kite. "Additional biomarker data to be presented will further
the understanding of pharmacodynamic mechanisms of KTE-C19 and the
importance of optimizing the conditioning chemotherapy regimen
prior to KTE-C19 therapy."
The accepted abstracts are listed below and are now
available online on the ASH conference website:
https://ash.confex.com/ash/2015/webprogram/start.html
2015 ASH Annual Meeting Presentations
Title: Pharmacodynamic Profile and Clinical
Response in Patients with B-Cell Malignancies of Anti-CD19 CAR
T-Cell Therapy
Date: Saturday, December 5, 2015: 5:30 – 7:30 PM Eastern
Session: 801. Gene Therapy and Transfer: Poster I Abstract number:
2042 Location: Orange County Convention Center, Hall A Presenter:
Adrian Bot, M.D., Ph.D., Kite Pharma, Santa Monica, CA
Title: Phase 1 Biomarker Analysis of the ZUMA-1
(KTE-C19-101) Study: A Phase 1-2 Multi-Center Study Evaluating the
Safety and Efficacy of Anti-CD19 CAR T Cells (KTE-C19) in Subjects
with Refractory Aggressive Non-Hodgkin Lymphoma (NHL)
Date: Sunday, December 6, 2015: 6:00 - 8:00 PM Eastern Session:
624. Lymphoma: Therapy with Biologic Agents, excluding Pre-Clinical
Models: Poster II Abstract number: 2730 Location: Orange County
Convention Center, Hall A Presenter: Sattya S. Neelapu, M.D., The
University of Texas MD Anderson Cancer Center, Houston, TX
Title: Phase 1 Clinical Results of
the ZUMA-1 (KTE-C19-101) Study: A Phase 1-2 Multi-Center Study
Evaluating the Safety and Efficacy of Anti-CD19 CAR T Cells
(KTE-C19) in Subjects with Refractory Aggressive Non-Hodgkin
Lymphoma (NHL)
Date: Monday, December 7, 2015: 6:00 – 8:00 PM Eastern Session:
624. Lymphoma: Therapy with Biologic Agents, excluding Pre-Clinical
Models: Poster III Abstract number: 3991 Location: Orange County
Convention Center, Hall A Presenter: Frederick L. Locke, M.D.,
Moffitt Cancer Center, Tampa, FL
Title: Cyclophosphamide and Fludarabine
Conditioning Chemotherapy Induces a Key Homeostatic Cytokine
Profile in Patients Prior to CAR T Cell Therapy
Date: Monday, December 7, 2015: 6:00 - 8:00 PM Eastern Session:
801. Gene Therapy and Transfer: Poster III Abstract number: 4426
Location: Orange County Convention Center, Hall A Presenter: Adrian
Bot, M.D., Ph.D., Kite Pharma, Santa Monica, CA
About Kite Pharma, Inc.
Kite Pharma, Inc., is a clinical-stage biopharmaceutical company
engaged in the development of novel cancer immunotherapy products,
with a primary focus on engineered autologous cell therapy (eACT™)
designed to restore the immune system's ability to recognize and
eradicate tumors. Kite is based in Santa Monica, CA. For
more information on Kite Pharma, please
visit www.kitepharma.com. Sign up to follow @KitePharma on
Twitter at www.twitter.com/kitepharma.
Forward-Looking Statements
This press release contains forward-looking statements for
purposes of the safe harbor provisions of the Private Securities
Litigation Reform Act of 1995. The press release may, in some
cases, use terms such as "predicts," "believes," "potential,"
"proposed," "continue," "estimates," "anticipates," "expects,"
"plans," "intends," "may," "could," "might," "will," "should" or
other words that convey uncertainty of future events or outcomes to
identify these forward-looking statements. Forward-looking
statements include statements regarding intentions, beliefs,
projections, outlook, analyses or current expectations concerning,
among other things: the progress and success of the Phase 2 portion
of the clinical trial of KTE-C19. Various factors may cause
differences between Kite's expectations and actual results as
discussed in greater detail in Kite's filings with the Securities
and Exchange Commission, including, without limitation, in its Form
10-Q for the quarter ended June 30, 2015. Any forward-looking
statements that are made in this press release speak only as of the
date of this press release. Kite assumes no obligation to update
the forward-looking statements whether as a result of new
information, future events or otherwise, after the date of this
press release.
CONTACT: Kite Pharma:
Cynthia M. Butitta, Chief Financial Officer
and Chief Operating Officer
310-824-9999
For Media: Justin Jackson
For Investor Inquiries: Lisa Burns
Burns McClellan
212-213-0006
jjackson@burnsmc.com
lburns@burnsmc.com
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