GTx, Inc. (Nasdaq: GTXI) today announced that it has been added to the Russell 3000® Index as part of the Russell U.S. Indexes annual reconstitution. The addition will take effect after the U.S. market opens on June 25.

Annual Russell U.S. Indexes reconstitution captures the 4,000 largest U.S. stocks as of May 11, ranking them by total market capitalization. Membership in the Russell 3000® Index, which remains in place for one year, means automatic inclusion in the large-cap Russell 1000® Index or small-cap Russell 2000® Index as well as the appropriate growth and value style indexes. FTSE Russell determines membership for its Russell U.S. Indexes primarily by objective, market-capitalization rankings and style attributes.

Russell U.S. Indexes are widely used by investment managers and institutional investors as the basis for index funds and as benchmarks for active investment strategies. Approximately $9 trillion in assets are benchmarked against Russell U.S. Indexes. Russell U.S. Indexes are part of FTSE Russell, a leading global index provider.

About GTx

GTx, Inc., headquartered in Memphis, Tenn., is a biopharmaceutical company dedicated to the discovery, development and commercialization of medicines to treat serious and/or significant unmet medical conditions, including stress urinary incontinence and prostate cancer.

Investor Contact:Argot PartnersKimberly Minarovich, 212-600-1902orSam Martin, 212-600-1902orMedia Contact:Red House ConsultingDenise Powell, 510-703-9491denise@redhousecomms.com

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