AstraZeneca: Lynparza Effective in Prostate Cancer
August 07 2019 - 3:08AM
Dow Jones News
By Carlo Martuscelli
AstraZeneca PLC (AZN.LN) said Wednesday that cancer drug
Lynparza met its primary objective in a clinical trial, making it
the only drug in its class with positive phase 3 study results for
prostate cancer.
The treatment, which is being developed in cooperation with
Merck & Co. (MRK), was able to slow disease progression in
patients with a specific prostate cancer type, AstraZeneca
said.
The British pharmaceutical company said that it will present the
full results from the PROfound trial at an upcoming medical
conference.
Lynparza was administered to previously treated men with
prostate cancer that was resistant to castration and with mutations
in their BRCA1/2 or ATM genes.
With this result the drug is the only one of its class, known as
PARP inhibitors, that has shown positive results in phase 3 trials
across ovarian, breast, pancreatic and prostate cancer, Astra
said.
Write to Carlo Martuscelli at carlo.martuscelli@dowjones.com
(END) Dow Jones Newswires
August 07, 2019 02:53 ET (06:53 GMT)
Copyright (c) 2019 Dow Jones & Company, Inc.
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