Statement of Additional Information Supplement

August 30, 2013

Morgan Stanley Institutional Fund, Inc.

Supplement dated August 30, 2013 to the Morgan Stanley Institutional Fund, Inc. (the "Fund") Statement of Additional Information dated August 19, 2013

Global Quality Portfolio

Effective September 1, 2013, John Gernon will replace Arthur Lev as President and Principal Executive Officer of the Fund. As a result, effective September 1, 2013, the following information hereby replaces in its entirety the biographical information for Mr. Lev contained in the Fund's Statement of Additional Information:

Name, Age and Address of
Executive Officer
  Position(s)
Held with
Registrant
  Length of
Time Served*
 

Principal Occupation(s) During Past 5 Years

 
John Gernon (50)
522 Fifth Avenue
New York, NY 10036
 

President and Principal Executive Officer – Equity, Fixed Income and AIP Funds

 

Since September 2013

 

President and Principal Executive Officer of the Equity and Fixed Income Funds and the Morgan Stanley AIP Funds (since September 2013) in the Fund Complex. Managing Director of the Adviser.

 

*  Each officer serves an indefinite term, until his or her successor is elected.

Please retain this supplement for future reference.