Kala Pharmaceuticals, Inc. (NASDAQ:KALA), a biopharmaceutical company focused on the development and commercialization of therapeutics using its proprietary AMPPLIFY™ mucus-penetrating particle (MPP) Drug Delivery Technology, today announced that members of its management team will participate in the following upcoming conferences in September:

2019 Wells Fargo Healthcare Conference Date: Thursday, September 5, 2019 Fireside Chat Time: 8:00 a.m. Location: Boston, MA

H.C. Wainwright 21st Annual Global Investment Conference Date: Tuesday, September 10, 2019 Presentation Time: 10:50 a.m. Location: New York, NY

To access a live webcast and subsequent archived recording of the presentations, please visit the “Investors & Media” section on the Kala website at http://kalarx.com

About Kala Pharmaceuticals, Inc.

Kala is a biopharmaceutical company focused on the development and commercialization of therapeutics using its proprietary AMPPLIFY™ mucus-penetrating particle (MPP) Drug Delivery Technology, with an initial focus on the treatment of eye diseases. Kala has applied the AMPPLIFY Drug Delivery Technology to a corticosteroid, loteprednol etabonate (LE), designed for ocular applications, resulting in the August 2018 FDA approval of INVELTYS® for the treatment of inflammation and pain following ocular surgery and its lead product candidate, KPI-121 0.25%, for the temporary relief of the signs and symptoms of dry eye disease.

Investors: Hannah Deresiewicz hannah.deresiewicz@sternir.com 212-362-1200

or

Media: Kari Watson kwatson@macbiocom.com 781-235-3060

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