Waters Collaborates with Dr. Sunghwan Kim of Kyungpook National University to Advance Precision Analysis of Complex Chemical ...
December 08 2020 - 6:00PM
Business Wire
Research collaboration will leverage the first
Waters SELECT SERIES CYCLIC IMS System in South Korea
NEWS SUMMARY:
- Waters and Dr. Sunghwan Kim expand collaborative research
relationship
- Dr. Kim’s continuing research will use Waters’ SELECT SERIES™
CYCLIC IMS™ system to investigate compounds in complex mixtures
such as petroleum and advanced materials used in electronics
- Newly published research by Waters and Dr. Kim yield findings
that isolate differing chemical compounds in crude oil down to
0.1Da using Waters CYCLIC IMS System
Waters Corporation (NYSE:WAT) has formally expanded its
long-standing, collaborative relationship with Dr. Sunghwan Kim of
Kyungpook National University to further explore the use of Waters’
cutting-edge ion mobility spectrometry (IMS) in the investigation
of compounds in complex mixtures.
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Waters SELECT SERIES CYCLIC IMS System
(Photo: Business Wire)
Identifying unknown chemicals in complex organic media at the
molecular level has become an important but difficult research
topic in modern analytical chemistry. For example, crude oils are
immensely complex organic mixtures and have a high degree of
variance at the chemical level. Characterization of the chemical
complexity of oil is helpful not only to maximize profit, but to
make petroleum products more efficient as well.
“We are thrilled to deliver the first Waters™ SELECT SERIES™
CYCLIC IMS™ in South Korea to Dr. Kim’s state-of-the-art laboratory
at Kyungpook National University,” said David Curtin, Waters’ Vice
President for APAC. “Together we will further explore difficult
analytical challenges, such as oil analysis, while leveraging our
collective expertise and revolutionary innovation.”
Characterization of oil’s chemical complexity prior to refining
is difficult, but necessary to maximize the quality of petroleum
products. Approximately 90 million barrels of oil are produced per
day, representing more than $3 billion in daily value*, so even
marginal improvements to the chemical characterization process can
have significant financial benefits for refineries.
Over the last 10 years, Dr. Kim has been working to develop an
analytical scheme to identify chemicals in complex mixtures and
believes that Waters’ CYCLIC IMS System can make a major
contribution to resolve this difficult analytical problem.
“The CYCLIC IMS is an innovative instrument by which researchers
can use their imagination to design and perform novel experiments
that has not been possible with other existing instruments,” said
Dr. Sunghwan Kim. “The novel information from this innovative
instrument can provide a key to complete the buildout of our
analytical scheme.”
While the performance of previous Ion Mobility ToF Mass
Spectrometry techniques has been useful for structural
characterization of crude oils, the approach has been limited by
the ion mobility resolution of these devices. The unique design of
the CYCLIC IMS utilizes a novel travelling wave ion mobility device
arranged in a cyclic fashion, allowing a selectable level of IMS
resolution by choosing the number of IMS cycles, and is delivering
previously unattainable levels of gas phase separation.
Recently, Dr. Kim published a paper with Waters researchers on
utilizing CYCLIC IMS to tackle both the complexity and isomer
problems of crude oil characterization. In this study many of the
chemical components differed by less than 0.1Da, and CYCLIC Ion
Mobility allowed the detection and separation of these, as well as
clean MSMS spectra for the individual components.
“The data obtained from utilizing Waters’ CYCLIC IMS clearly
demonstrates that the novel CYCLIC ion mobility-mass spectrometer
is a powerful instrument that can provide never-before-seen tandem
mass spectra of individual compounds in crude oil,” said Dr. Kim.
“Furthermore, it has the potential to reduce the need for long LC
or GC separations prior to MS analysis, reducing overall analysis
time and increasing throughput.”
In addition, as part of their collaboration, Dr. Kim and Waters
will also work to characterize complex advanced materials used in
high technology products, such as those found in electronics. In
this fast-moving field of smart materials, the structural purity of
these finely tailored molecules dictates the ultimate performance
of the materials and even subtle changes in organization of side
chains, functional units or macro-molecular assemblies can lead to
batch-level failures, or even potentially dangerous products. The
use of CYCLIC IMS in process development will allow detection of
erroneous molecules that could not be seen before.
*Source: US Energy Information Administration
About Waters Corporation
Waters Corporation (NYSE:WAT), the world's leading specialty
measurement company, has pioneered chromatography, mass
spectrometry, and thermal analysis innovations serving the life,
materials, and food sciences for more than 60 years. With more than
7,000 employees worldwide, Waters operates directly in 35
countries, including 15 manufacturing facilities, and with products
available in more than 100 countries.
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Queenie Ng Asia-Pacific Communications Waters Corporation
Queenie_Ng@waters.com
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