PART
II
INFORMATION
NOT REQUIRED IN PROSPECTUS
Indemnification
of Directors, Officers, Employees and Agents
Under
the Companies Law, a company may not exculpate an office holder from liability for a breach of the duty of loyalty. A company
may exculpate an office holder in advance from liability to the company, in whole or in part, for damages caused to the company
as a result of a breach of the duty of care but only if a provision authorizing such exculpation is included in its articles of
association. Our amended and restated articles of association include such a provision. An Israeli company may not exculpate a
director from liability arising out of a breach of the duty of care with respect to a dividend or distribution to shareholders.
Under
the Companies Law and the Securities Law, 5738—1968, or the Securities Law, a company may indemnify an office holder in
respect of the following liabilities, payments and expenses incurred for acts performed as an office holder, either pursuant to
an undertaking made in advance of an event or following an event, provided a provision authorizing such indemnification is contained
in its articles of association:
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a
monetary liability incurred by or imposed on him or her in favor of another person pursuant to a judgment, including a settlement
or arbitrator’s award approved by a court. However, if an undertaking to indemnify an office holder with respect to
such liability is provided in advance, then such undertaking must be limited to certain events which, in the opinion of the
board of directors, can be foreseen based on the company’s activities when the undertaking to indemnify is given, and
to an amount or according to criteria determined by the board of directors as reasonable under the circumstances, and such
undertaking shall detail the foreseen events and described above amount or criteria;
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reasonable
litigation expenses, including reasonable attorneys’ fees, incurred by the office holder as (1) a result of an investigation
or proceeding instituted against him or her by an authority authorized to conduct such investigation or proceeding, provided
that (i) no indictment was filed against such office holder as a result of such investigation or proceeding; and (ii) no financial
liability was imposed upon him or her as a substitute for the criminal proceeding as a result of such investigation or proceeding
or, if such financial liability was imposed, it was imposed with respect to an offense that does not require proof of criminal
intent; or (2) in connection with a monetary sanction; a monetary liability imposed on him or her in favor of an injured party
at an Administrative Procedure (as defined below) pursuant to Section 52(54)(a)(1)(a) of the Securities Law;
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expenses
incurred by an office holder in connection with an Administrative Procedure under the Securities Law, including reasonable
litigation expenses and reasonable attorneys’ fees; and
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reasonable
litigation expenses, including attorneys’ fees, incurred by the office holder or imposed by a court in proceedings instituted
against him or her by the company, on its behalf or by a third party or in connection with criminal proceedings in which the
office holder was acquitted or as a result of a conviction for an offense that does not require proof of criminal intent.
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“Administrative
Procedure” is defined as a procedure pursuant to chapters H3 (Monetary Sanction by the Israeli Securities Authority), H4
(Administrative Enforcement Procedures of the Administrative Enforcement Committee) or I1 (Arrangement to prevent Procedures or
Interruption of procedures subject to conditions) to the Securities Law.
Under
the Companies Law and the Securities Law, a company may insure an office holder against the following liabilities incurred for
acts performed by him or her as an office holder if and to the extent provided in the company’s articles of association:
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a
breach of duty of care to the company or to a third party, to the extent such a breach arises out of the negligent conduct
of the office holder;
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a
breach of duty of loyalty to the company, provided that the office holder acted in good faith and had a reasonable basis to
believe that the act would not harm the company;
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a
monetary liability imposed on the office holder in favor of a third party;
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a
monetary liability imposed on the office holder in favor of an injured party at an Administrative Procedure pursuant to Section
52(54)(a)(1)(a) of the Securities Law; and
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expenses
incurred by an office holder in connection with an Administrative Procedure, including reasonable litigation expenses and
reasonable attorneys’ fees.
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Under
the Companies Law, a company may not indemnify, exculpate or insure an office holder against any of the following:
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a
breach of duty of loyalty, except for indemnification and insurance for a breach of the duty of loyalty to the company to
the extent that the office holder acted in good faith and had a reasonable basis to believe that the act would not harm the
company;
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a
breach of the duty of care committed intentionally or recklessly, excluding a breach arising out of the negligent conduct
of the office holder;
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an
act or omission committed with intent to derive illegal personal benefit; or
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a
fine or forfeit levied against the office holder.
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Under
the Companies Law, exculpation, indemnification and insurance of office holders must be approved by the compensation committee
and the board of directors and, with respect to certain office holders or under certain circumstances, also by the shareholders.
Our
amended and restated articles of association permit us to, exculpate, indemnify and insure our office holders as permitted under
the Companies Law. Our office holders are currently covered by a directors and officers’ liability insurance policy. As
of the date of this registration statement, no claims for directors’ and officers’ liability insurance have been filed
under this policy, we are not aware of any pending or threatened litigation or proceeding involving any of our directors or officers
in which indemnification is sought, nor are we aware of any pending or threatened litigation that may result in claims for indemnification
by any director or officer.
In
the opinion of the SEC, however, indemnification of directors and office holders for liabilities arising under the Securities
Act is against public policy and therefore unenforceable.
Recent
Sales of Unregistered Securities
Set
forth below are the sales of all securities of the registrant sold by the registrant within the past three years which were not
registered under the Securities Act:
On
June 20, 2016, the Company entered into a Consulting Service Agreement with PCG Advisory Group (“PCG”), pursuant to
which PCG undertook to provide the Company with markets advisory, investor relations and media strategies for a period of 7 months
commencing the date of the agreement. As partial consideration for the above services, the Company agreed to issue to PCG 50,000
ordinary shares for each calendar month of the term. The Company issued 350,000 ordinary shares to PCG.
On
October 18, 2016, the Company entered into a Consulting Agreement with a consultant (the “Consultant”), pursuant to
which the Consultant undertook to provide strategic cooperation and technology consulting for a period of two years from the date
of the agreement. Unless terminated, the agreement will be automatically renewed for consecutive one-year periods. Based on the
agreement, the Company issued to the Consultant 620,521 warrants to purchase ordinary shares of the Company at an exercise price
of NIS 0.01 (approximately $0.0026) per share. The Consultant has exercised all of the warrants.
In
October 2017, the Company signed a share purchase agreement with certain investors for an investment of $625,000 in exchange for
the issuance of 1,061,125 ordinary shares.
On
November 18, 2018, the Company signed a share purchase agreement with an investor for an investment of $100,000 in exchange for
the issuance of 800,000 ordinary shares and 600,000 warrants with a three year exercise period at an exercise price of the lower
of $0.125 or the lowest price during the 5 trading days before the exercise notice.
On
February 27, 2019, the Company entered into a joint venture agreement with Amarantus, pursuant to which the Company issued 17,986,999
Ordinary Shares, representing 19.99% of the Company, to Amarantus, in exchange for Amarantus transferring to the Company 19.99%
of the outstanding equity securities of Breakthrough, a wholly owned subsidiary of Amarantus, and for Amarantus assigning the
University of Leipzig License Agreement to Breakthrough.
The
Company recently raised $1,215,450 from the sale of convertible notes, which have an outstanding principal balance of $1,350,500.
On February 27, 2019, we entered into a convertible bridge loan agreement, and have issued notes and warrants relating thereto,
to obtain loans from several private lenders, including DPH Investment Ltd., a holder of 11.5% of our shares (as of such date),
to finance the Company’s activities through the consummation of a proposed public offering and our planned uplisting to
the NASDAQ Capital Market. As of April 15, 2019, we have obtained $1,010,500 in bridge loan financing, and have commitments for
an additional $340,000 subject to certain milestones. The loans, which have an original issue discount of ten percent (10%), bear
interest at a flat rate of ten percent (10%) and have a maturity date six months after receipt of the loan funds. The loans are
convertible into ordinary shares of the Company after the maturity date at a conversion price equal to 70% of the average closing
bid price of the Company’s Ordinary Shares in the five days prior to the conversion. In the event the Company defaults under
the loan agreement, the conversion price will be reduced to 60% of the average closing bid price of the Company’s Ordinary
Shares in the 15 days prior to the conversion. In addition, each lender received a warrant to purchase an amount of ordinary shares
equal to 25% of the amount loaned by such lender, with the warrant exercise price to be equal to the offering price in the proposed
public offering, or, in the event its loan is converted into shares, the warrant exercise price will be equal to the applicable
closing bid price of the Company’s shares at the time of the conversion of the loan. The warrants may be exercised only
during the period beginning on the date that is six months after the date that the warrant exercise price and the number of warrant
shares are determined and ending on the date that is three years thereafter.
On
March 10, 2019, we entered into an amendment to the bridge loan agreement. The amendment provides for a 10% penalty if we repay
the loan prior to the maturity date. In addition, we agreed to grant each lender a warrant to purchase an additional amount of
ordinary shares equal to 25% of the amount loaned by such lender, under the same terms as the original warrant, but with a warrant
exercise price equal to 150% of the closing bid price of our shares on the day prior to the closing of the bridge loan transaction.
We
claimed exemption from registration under the Securities Act for these issuances described above under Section 4(a)(2) or Regulation
S promulgated under the Securities Act, as well as, with respect to grants of share options, under Rule 701 of the Securities
Act as transactions pursuant to written compensatory plans or pursuant to a written contract relating to compensation. No form
of general solicitation or general advertising was conducted in connection with any of these sales, and no underwriters were employed.
Exhibits
and Financial Statement Schedules
(a)
Exhibits: The following exhibits are included herein or incorporated herein by reference
Exhibit
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Description
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1.1
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Form of Underwriting Agreement (filed as Exhibit 1.1 to the Company’s Amendment No. 1 to Form F-1 (File No. 333-230981) filed on July 3, 2019 and incorporated herein by reference).
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3.1
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Amended and Restated Articles of Association of Todos Medical Ltd. (filed as Exhibit 99.1 to the Company’s current report on Form 6-K (File No. 333-209744) filed on March 30, 2017 and incorporated herein by reference).
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4.1
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Form of Underwriter’s Warrant (filed as Exhibit 4.1 to the Company’s Amendment No. 1 to Form F-1 (File No. 333-230981) filed on July 3, 2019 and incorporated herein by reference).
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4.2
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Form of Public Warrant (filed as Exhibit 4.2 to the Company’s Amendment No. 2 to Form F-1 (File No. 333-230981)).
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5.1
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Opinion of SRK Kronengold Law Offices regarding the legality of the securities being registered (filed as Exhibit 5.1 to the Company’s Amendment No. 1 to Form F-1 (File No. 333-230981) filed on July 3, 2019 and incorporated herein by reference).
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10.1
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Research and License Agreement with B.G. Negev Technologies and Applications Ltd. and Mor Research Applications Ltd., dated April 26, 2010, as amended June 25, 2012 (filed as Exhibit 10.1 to the Company’s registration statement on Form F-1 (File No. 333-209744) filed on February 26, 2016, and incorporated herein by reference).
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10.2
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Addendum No. 2 to Research and License Agreement Dated March 19, 2017, as amended on June 25, 2012 with B.G. Negev Technologies and Applications Ltd. and Mor Research Applications Ltd. (filed as Exhibit 4.2 to Form 20-F (File No. 333-209744) filed on May 1, 2017 and incorporated herein by reference).
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10.3
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Summary English Translation of Lease Agreement for Corporate Offices in Rehovot, Israel (filed as Exhibit 10.4 to the Company’s registration statement on Form F-1 (File No. 333-209744) filed on February 26, 2016 and incorporated herein by reference).
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10.4
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Todos Medical Ltd. 2015 Israeli Share Option Plan (filed as Exhibit 10.7 to the Company’s registration statement on Form F-1 (File No. 333-209744) filed on February 26, 2016 and incorporated herein by reference).
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10.5
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Employment Agreement, dated March 16, 2017, between Todos Medical Singapore Pte Ltd. and Dr. Wee Yue Chew and warrant agreement, dated March 16, 2017, between Todos Medical Ltd. and Dr. Wee Yue Chew (filed as Exhibit 4.12 to Form 20-F (File No. 333-209744) filed on May 1, 2017, and incorporated herein by reference).
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10.6
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Convertible Bridge Loan Agreement, dated February 27, 2019, (filed as Exhibit 4.1 to the Company’s Form 6-K filed on February 28, 2019, and incorporated herein by reference).
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10.7
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Amendment to Convertible Bridge Loan Agreement, dated February 27, 2019, (filed as Exhibit 4.1 to the Company’s Form 6-K filed on March 12, 2019, and incorporated herein by reference).
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10.8
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Share Purchase and Assignment of License Agreement among Todos Medical Ltd., Amarantus Bioscience Holdings, Inc., and Breakthrough Diagnostics, Inc., dated February 27, 2019, (filed as Exhibit 4.4 to the Company’s Form 6-K filed on February 28, 2019, and incorporated herein by reference).
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10.9
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Assignment and Loan Conversion Agreement among the Company, Adeline Holdings Ltd., Yitzhak Ostrovitsky, and Sorry Doll Ltd. and S.B. Nihul Merkakein Ltd., dated November 28, 2018, (filed as Exhibit 4.9 to the Company’s Form 20-F filed on March 28, 2019, and incorporated herein by reference).
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10.10
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Marketing and Reseller Agreement, between the Company and Care G.B. Plus Ltd., dated December 20, 2018, (filed as Exhibit 4.10 to the Company’s Form 20-F filed on March 28, 2019, and incorporated herein by reference).
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10.11
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Employment Agreement between the Company and Dr. Herman Weiss, dated March 25, 2019 (filed as Exhibit 10.11 to the Company’s Amendment No. 1 to Form F-1 (File No. 333-230981) filed on July 3, 2019, and incorporated herein by reference).
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23.1
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Consent of Fahn Kanne, Grant Thornton (filed as Exhibit 23.1 to the Company’s Amendment No. 1 to Form F-1 (File No. 333-230981) filed on July 3, 2019 and incorporated herein by reference).
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23.2
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Consent of Legal Counsel (incorporated in Exhibit 5.1).
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24.1
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Power of Attorney (contained on the signature page of the registration statement).
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Undertakings
The
undersigned Registrant hereby undertakes to:
(a) file,
during any period in which offers or sales are being made, a post-effective amendment to this registration statement to:
(i) include
any prospectus required by section 10(a)(3) of the Securities Act;
(ii) reflect
in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective
amendment thereof) which, individually or together, represent a fundamental change in the information in the registration statement.
Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities
offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering
range may be reflected in the form of prospectus filed with the SEC pursuant to Rule 424(b) if, in the aggregate, the changes
in volume and price represent no more than a 20% change in the maximum aggregate offering price set forth in the “Calculation
of Registration Fee” table in the effective registration statement; and
(iii) include
any material information with respect to the plan of distribution not previously disclosed in this registration statement or any
material change to such information in the registration statement.
(b) that,
for the purpose of determining any liability under the Securities Act, each post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed
to be the initial bona fide offering thereof.
(c) to
file a post-effective amendment to remove from registration any of the securities that remain unsold at the end of the offering.
(d) that
insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling
persons of the Registrant, the Registrant has been advised that in the opinion of the SEC, such indemnification is against public
policy as expressed in the Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities
(other than the payment by the Registration of expenses incurred or paid by a director, officer or controlling person to the Registrant
in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection
with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by
controlling precedent, submit to a court of appropriate jurisdiction the question of whether such indemnification by it is against
public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.
(e) that,
for the purpose of determining liability under the Securities Act to any purchaser, each prospectus filed pursuant to Rule 424(b)
as part of a registration statement relating to an offering, other than registration statements relying on Rule 430B or other
than prospectuses filed in reliance on Rule 430A, shall be deemed to be part of and included in the registration statement as
of the date it is first used after effectiveness. Provided, however, that no statement made in a registration statement or prospectus
that is part of the registration statement or made in a document incorporated or deemed incorporated by reference into the registration
statement or prospectus that is part of the registration statement will, as to a purchaser with a time of contract of sale prior
to such first use, supersede or modify any statement that was made in the registration statement or prospectus that was part of
the registration statement or made in any such document immediately prior to such date of first use.
(f) that,
for the purpose of determining liability of the Registrant under the Securities Act to any purchaser in the initial distribution
of the securities, regardless of the underwriting method used to sell the securities to the purchaser, if the securities are offered
or sold to such purchaser by means of any of the following communications, the Registrant will be a seller to the purchaser and
will be considered to offer or sell such securities to such purchaser:
(i) any
preliminary prospectus or prospectus of the Registrant relating to the offering filed pursuant to Rule 424;
(ii) any
free writing prospectus relating to the offering prepared by or on behalf of the Registrant or used or referred to by the Registrant;
(iii) the
portion of any other free writing prospectus relating to the offering containing material information about the Registrant or
its securities provided by or on behalf of the Registrant; and
(iv) any
other communication that is an offer in the offering made by the Registrant to the purchaser.