RNS Number:0035X
Alizyme PLC
10 January 2001






FOR IMMEDIATE RELEASE                        10th January 2001




ALIZYME PLC



DIRECTORS SHAREHOLDINGS







Pursuant to the recent Placing and Open Offer by the Company, the completion
of which was announced on 4 August 2000, the following directors of Alizyme
plc have been allotted new Ordinary Shares of 2p each as detailed below:




             No. of New Ordinary     Total No. of Ordinary Shares Following the
             Shares Allotted         Placing & Open Offer

Sir Brian  Richards       22,580                  319,373


John Gordon               36,875                  331,875

William Edge              10,000                  333,873










For further information, please contact:


Dr Richard Palmer, Chief Executive Officer    Tel No: + 44 (0) 1223 423070
Mr Tim McCarthy, Finance Director
ALIZYME plc


Lisa Baderoon                                    Tel No: + 44 (0) 20 7466 5000
BUCHANAN COMMUNICATIONS



Further information on Alizyme can be found on the Company's website:
www.alizyme.co.uk



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