Statement of Changes in Beneficial Ownership (4)

FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person ^* KIRK RANDAL J	2. Issuer Name and Ticker or Trading Symbol PRECIGEN, INC. [ PGEN ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director __X__ 10% Owner _____ Officer (give title below) _____ Other (specify below)
(Last) (First) (Middle) C/O THIRD SECURITY, LLC, 1881 GROVE AVENUE	3. Date of Earliest Transaction (MM/DD/YYYY) 6/3/2021
(Street) RADFORD, VA 24141 (City) (State) (Zip)	4. If Amendment, Date Original Filed (MM/DD/YYYY)	6. Individual or Joint/Group Filing (Check Applicable Line) _X _ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	3. Trans. Code (Instr. 8)		4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock	6/3/2021		J⁽¹⁾		354557 ⁽¹⁾	A	⁽¹⁾	18684553	I	by R.J. Kirk DOT ⁽³⁾
Common Stock	6/3/2021		J⁽¹⁾		5663 ⁽¹⁾	A	⁽¹⁾	479857	I	by JPK 2008 ⁽³⁾
Common Stock	6/3/2021		J⁽¹⁾		56638 ⁽¹⁾	A	⁽¹⁾	3597953	I	by JPK 2009 ⁽³⁾
Common Stock	6/3/2021		J⁽¹⁾		22655 ⁽¹⁾	A	⁽¹⁾	1612186	I	by JPK 2012 ⁽³⁾
Common Stock	6/3/2021		J⁽¹⁾		3398 ⁽¹⁾	A	⁽¹⁾	447405	I	by Kellie L. Banks LTT ⁽³⁾
Common Stock	6/3/2021		J⁽¹⁾		5663 ⁽¹⁾	A	⁽¹⁾	478894	I	by MGK 2008 ⁽³⁾
Common Stock	6/3/2021		J⁽¹⁾		56638 ⁽¹⁾	A	⁽¹⁾	3838992	I	by MGK 2009 ⁽³⁾
Common Stock	6/3/2021		J⁽¹⁾		22655 ⁽¹⁾	A	⁽¹⁾	1594863	I	by MGK 2011 ⁽³⁾
Common Stock	6/3/2021		J⁽¹⁾		5663 ⁽¹⁾	A	⁽¹⁾	567535	I	by ZSK 2008 ⁽³⁾
Common Stock	6/3/2021		J⁽¹⁾		4531 ⁽¹⁾	A	⁽¹⁾	342685	I	by ZSK 2009 ⁽³⁾
Common Stock	6/3/2021		J⁽¹⁾		14159 ⁽¹⁾	A	⁽¹⁾	989243	I	by Sr. Staff 2015 ⁽³⁾
Common Stock	6/3/2021		J⁽²⁾		14168 ⁽²⁾	A	⁽²⁾	989252	I	by Staff 2015 ⁽³⁾
Common Stock								1592206	I	by Staff 2010 ⁽³⁾
Common Stock								1383858	I	by Staff 2009 ⁽³⁾
Common Stock								2976063	I	by Sr. Staff 2008 ⁽³⁾
Common Stock								691929	I	by Incentive 2009 ⁽³⁾
Common Stock								1260538	I	by Incentive 2010 ⁽⁴⁾
Common Stock								213805	I	by ADC 2010 ⁽⁴⁾
Common Stock								14140139	I	by Kapital Joe ⁽⁴⁾
Common Stock								311287	I	by Staff 2001 ⁽⁴⁾
Common Stock								58800	I	by Sr. Staff ⁽⁴⁾
Common Stock								1403	I	by Lotus ⁽⁴⁾
Common Stock								59133	I	by Staff 2006 ⁽⁴⁾
Common Stock								118266	I	by Sr. Staff 2006 ⁽⁴⁾
Common Stock								19711	I	by Incentive 2006 ⁽⁴⁾
Common Stock								4995000	I	by Sr. Staff 2007 ⁽⁴⁾
Common Stock								2497500	I	by Staff 2007 ⁽⁴⁾
Common Stock								832500	I	by Incentive 2007 ⁽⁴⁾
Common Stock								16406828	I	by Sunset 2020 ⁽⁴⁾
Common Stock								1144481	I	by Spouse

*Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)*
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	4. Trans. Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)			11. Nature of Indirect Beneficial Ownership (Instr. 4)

Explanation of Responses:
(1)	On June 3, 2021, the indicated number of shares were received as a distribution of issuer common stock from the Harvest Intrexon Enterprise Fund I LP.
(2)	On June 3, 2021, the indicated number of shares were received as a distribution of issuer common stock from the Harvest Intrexon Enterprise Fund I (AI) LP.
(3)	Randal J. Kirk controls each of R.J. Kirk Declaration of Trust ("R.J. Kirk DOT"), JPK 2008 LLC ("JPK 2008"), JPK 2009 LLC ("JPK 2009"), JPK 2012 LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008 LLC ("MGK 2008"), MGK 2009 LLC ("MGK 2009"), MGK 2011 ("MGK 2011"), ZSK 2008 LLC ("ZSK 2008"), ZSK 2009 LLC ("ZSK 2009"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), Third Security Staff 2010 LLC ("Staff 2010"), Third Security Staff 2009 LLC ("Staff 2009"), Third Security Senior Staff 2008 LLC ("Sr. Staff 2008"), and Third Security Incentive 2009 LLC ("Incentive 2009"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.
(4)	Randal J. Kirk controls each of Third Security Incentive 2010 LLC ("Incentive 2010"), ADC 2010, LLC ("ADC 2010"), Kapital Joe, LLC ("Kapital Joe"), Third Security Staff 2001 LLC ("Staff 2001"), Third Security Senior Staff LLC ("Sr. Staff"), Lotus Capital (2000) Company, Inc. ("Lotus"), Third Security Staff 2006 LLC ("Staff 2006"), Third Security Senior Staff 2006 LLC ("Sr. Staff 2006"), Third Security Incentive 2006 LLC ("Incentive 2006"), Third Security Senior Staff 2007 LLC ("Sr. Staff 2007"), Third Security Staff 2007 LLC ("Staff 2007"), Third Security Incentive 2007 LLC ("Incentive 2007"), and Sunset 2020 LLC ("Sunset 2020"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

Reporting Owners
Reporting Owner Name / Address	Relationships
Reporting Owner Name / Address	Director	10% Owner	Officer	Other
KIRK RANDAL J C/O THIRD SECURITY, LLC 1881 GROVE AVENUE RADFORD, VA 24141	X	X