Item 5.02.
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Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.
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Effective January 1, 2022,
the Board of Directors (the “Board”) of NeuBase Therapeutics, Inc. (the “Company”) appointed Eric Ende, M.D.,
to the Board as a Class III director of the Company.
Dr. Ende, age 53, is the President of Ende BioMedical
Consulting Group, Inc., a privately held consulting company focused on the life sciences industry, a position he has held since 2009.
Since May 2017, Dr. Ende has been a member of the board of directors of Matinas BioPharma, Inc. (NYSE: MTNB), a clinical-stage biopharmaceutical
company, where he chairs the Compensation Committee and serves on the Audit and Nominating & Corporate Governance Committees. Since
December 2018, Dr. Ende has been a member of the board of directors of Avadel plc (Nasdaq: AVDL), a clinical-stage biopharmaceutical company,
where he chairs the Nominating & Corporate Governance Committee and serves on the Audit Committee. From November 2019 to June 2020,
Dr. Ende served on the board of directors of Progenics Pharmaceuticals, Inc. (Nasdaq: PGNX), a biopharmaceutical company, where he also
chaired the Compensation Committee and was a member of the Audit and Science Committees. From 2010 to 2011, Dr. Ende served on the board
of directors and as a member of the Audit and Risk Management Committees of Genzyme Corp. (Nasdaq: GENZ), a biotechnology company, until
it was acquired in 2011 by Sanofi S.A. From 2002 through 2008, Dr. Ende was the senior biotechnology analyst at Merrill Lynch; from 2000
through 2002, he was the senior biotechnology analyst at Bank of America Securities; and from 1997 to 2000, he was a biotechnology analyst
at Lehman Brothers. Dr. Ende received an MBA in Finance and Accounting from NYU - Stern Business School in 1997, an MD from
Mount Sinai School of Medicine in 1994, and a BS in Biology and Psychology from Emory University in 1990.
In accordance with the
Company’s outside director compensation policy (the “Director Compensation Policy”) and in connection with Dr. Ende’s
appointment to the Board, on January 3, 2022, Dr. Ende will be granted a stock option to purchase shares of Company common stock having
a grant date fair value of $320,000, rounded down to the nearest whole share, with an exercise price equal to the fair market value of
the Company’s common stock on the date of grant. Twenty-five percent of the shares subject to the option will vest on the one-year
anniversary of the grant date, and the remaining portion of the shares subject to the option will vest on an equal monthly basis over
the following 36 months, in each case subject to Dr. Ende’s continuous service through such date and subject to acceleration as
described in the Director Compensation Policy.
As a non-employee director
of the Company, Dr. Ende will also be entitled to receive cash compensation for his service on the Board and any committees on which he
serves, as well as (beginning on the first business day following the Company’s 2022 annual meeting of stockholders) an annual stock
option award, in each case in accordance with the terms of the Director Compensation Policy. The full text of the Director Compensation
Policy was filed as Exhibit 10.1 to the Company’s Current Report on Form 8-K filed with the Securities and Exchange Commission on
September 11, 2020 and is incorporated herein by reference.
The Company also entered
into an indemnity agreement with Dr. Ende in the same form as its standard form of indemnification agreement with its other directors.
There are no family relationships
between Dr. Ende and any director or executive officer of the Company, and he was not selected by the Board to serve as a director pursuant
to any arrangement or understanding with any person. Dr. Ende has not engaged in any transaction that would be reportable as a related
party transaction under Item 404(a) of Regulation S-K.