As filed with the Securities and
Exchange Commission on October 29, 2020
Registration
No. 333-
UNITED STATES
SECURITIES AND EXCHANGE
COMMISSION
WASHINGTON, D.C.
20549
FORM S-1
REGISTRATION
STATEMENT
UNDER
THE SECURITIES ACT
OF 1933
Hepion Pharmaceuticals,
Inc.
(Exact Name of Registrant as
Specified in its Charter)
Delaware
(State or other jurisdiction of
incorporation or organization) |
2834
(Primary Standard Industrial
Classification Code Number) |
46-2783806
(I.R.S. Employer
Identification Number) |
399 Thornall Street, First
Floor
Edison, NJ 08837
(732) 902-4000
(Address, including zip code, and
telephone number, including area code, of Registrant’s principal
executive offices)
Robert Foster
Chief Executive
Officer
Hepion
Pharmaceuticals, Inc.
399 Thornall Street, First
Floor
Edison, NJ 08837
(732) 902-4000
(Name, address, including zip code,
and telephone number, including area code, of agent for
service)
Copies
to: |
Jeffrey
J. Fessler, Esq.
Sheppard, Mullin, Richter & Hampton LLP
30 Rockefeller Plaza
New York, NY 10112
Tel.: (212) 634-3067 |
Brad L. Schiffman,
Esq.
Melissa Palat Murawsky,
Esq.
Blank Rome LLP
1271 Avenue of the
Americas
New York, NY 10020
Tel: (212) 885-5442
|
Approximate date of commencement
of proposed sale to the public: As soon as practicable after the
effective date hereof.
If
any of the securities being registered on this Form are to be
offered on a delayed or continuous basis pursuant to Rule 415
under the Securities Act of 1933, check the following box:
¨
If
this Form is filed to register additional securities for an
offering pursuant to Rule 462(b) under the Securities Act,
please check the following box and list the Securities Act
registration statement number of the earlier effective registration
statement for the same offering. ¨
If
this Form is a post-effective amendment filed pursuant to
Rule 462(c) under the Securities Act, check the following box
and list the Securities Act registration statement number of the
earliest effective registration statement for the same
offering. ¨
If
this Form is a post-effective amendment filed pursuant to
Rule 462(d) under the Securities Act, check the following box
and list the Securities Act registration statement number of the
earliest effective registration statement for the same
offering. ¨
Indicate by check mark whether the
registrant is a large accelerated filer, an accelerated filer, a
non-accelerated filer, a smaller reporting company or an emerging
growth company. See the definitions of “large accelerated filer,”
“accelerated filer,” “smaller reporting company” and “emerging
growth company” in Rule 12b-2 of the Exchange Act. (Check
one):
Large accelerated filer ¨ |
Accelerated filer ¨ |
Non-accelerated filer x |
Smaller reporting company x
Emerging growth company x
|
If an
emerging growth company, indicate by check mark if the registrant
has elected not to use the extended transition period for complying
with any new or revised financial accounting standards provided to
Section 7(a)(2)(B) of the Securities Act. x
CALCULATION OF REGISTRATION
FEE
Title of Each Class of Securities
to Be Registered |
|
Proposed Maximum Aggregate
Offering Price(1) |
|
|
Amount of
Registration
Fee(2) |
|
Common Stock, $0.0001 par value per
share (3) |
|
$ |
34,500,000 |
|
|
$ |
3,764 |
|
(1) Estimated solely for the purpose
of calculating the registration fee pursuant to Rule 457(o) under
the Securities Act of 1933, as amended (the "Securities
Act").
(2) Calculated pursuant to Rule
457(o) based on an estimate of the proposed maximum aggregate
offering price.
(3) Includes shares of common stock
which may be issued on exercise of a 45-day option granted to the
underwriters to cover over-allotments, if any.
The
Registrant hereby amends this Registration Statement on such date
or dates as may be necessary to delay its effective date until the
Registrant shall file a further amendment which specifically
states that this Registration Statement shall thereafter become
effective in accordance with Section 8(a) of the Securities
Act of 1933, or until the Registration Statement shall become
effective on such date as the Commission, acting pursuant to said
Section 8(a), may determine.
The information contained in this
preliminary prospectus is not complete and may be changed. These
securities may not be sold until the registration statement filed
with the Securities and Exchange Commission is effective. This
preliminary prospectus is not an offer to sell these securities and
it is not soliciting an offer to buy these securities in any state
where the offer or sale is not permitted.
PRELIMINARY
PROSPECTUS |
|
SUBJECT
TO COMPLETION |
|
DATED
OCTOBER 29, 2020 |
Hepion
Pharmaceuticals, Inc.
We are offering
shares
of our common stock, par value $0.0001 per share.
Our common stock is listed on The
Nasdaq Capital Market (“Nasdaq”), under the symbol “HEPA.” On
October 28, 2020, the last reported sale price of our common stock
was $3.26 per share.
The final public offering price of
the shares of common stock in this offering will be determined
through negotiation between us and the underwriters in the offering
and the recent market price used throughout this prospectus may not
be indicative of the final offering price.
We are an “emerging growth company”
under the federal securities laws and have elected to comply with
certain reduced public company reporting requirements.
Investing in our common stock
involves a high degree of risk. See “Risk Factors” beginning on
page 6. Neither the Securities and Exchange Commission nor any
state securities commission has approved or disapproved of these
securities or determined if this prospectus is truthful or
complete. Any representation to the contrary is a criminal
offense.
|
|
Per Share |
|
|
Total |
|
Public offering price |
|
$ |
|
|
|
$ |
|
|
Underwriting
discounts and commissions(1) |
|
$ |
|
|
|
$ |
|
|
Proceeds to us, before expenses |
|
$ |
|
|
|
$ |
|
|
|
(1) |
We
refer you to “Underwriting” beginning on page 14 for additional
information regarding underwriters’ compensation. |
We have granted a 45-day option to
the representative of the underwriters to purchase up
to additional
shares of common stock solely to cover over-allotments, if
any.
The underwriters
expect to deliver the
shares of common stock to the purchasers on or
about ,
2020.
ThinkEquity
a division of Fordham Financial
Management, Inc.
The date of this prospectus
is ,
2020
TABLE OF CONTENTS
You
should rely only on the information contained or incorporated by reference in this
prospectus or in any free writing prospectus that we may authorize
to be delivered or made available to you. We and the underwriters
have not authorized anyone to provide you with different
information. We are offering to sell, and seeking offers to buy,
our securities only in jurisdictions where such offers and sales
are permitted. The information in this prospectus is accurate only
as of its date, regardless of the time of its delivery or any sale
of our securities.
Persons outside the United States who
come into possession of this prospectus must inform themselves
about, and observe any restrictions relating to, the offering of
our securities and the distribution of the prospectus outside the
United States.
ABOUT THIS
PROSPECTUS
In this prospectus, “Hepion,” “the
Company,” “we,” “us,” and “our” refer to Hepion
Pharmaceuticals, Inc., a Delaware corporation, and its
subsidiaries, unless the context otherwise requires.
This
prospectus describes the specific information about the terms of
this offering, the shares of common stock that we are selling and
the risks of investing in our common stock. You should read this
prospectus, any free writing prospectus and the information
incorporated by reference in this prospectus before making your
investment decision. See
“Where You Can Find More Information.” If any statement in
one of these documents is inconsistent with a statement in another
document having a later date – for example, a document incorporated
by reference in this prospectus – the statement in the document
having the later date modifies or supersedes the earlier
statement.
Neither we, nor any of our officers,
directors, agents or representatives or underwriters, make any
representation to you about the legality of an investment in our
common stock. You should not interpret the contents of this
prospectus or any free writing prospectus to be legal, business,
investment or tax advice. You should consult with your own advisors
for that type of advice and consult with them about the legal, tax,
business, financial and other issues that you should consider
before investing in our securities.
PROSPECTUS SUMMARY
This summary highlights certain
information appearing elsewhere in this prospectus and the
documents incorporated by reference. This summary does not contain
all of the information you should consider before investing in our
common shares. You should read this entire prospectus and the
documents incorporated by reference into this prospectus carefully
before making an investment decision. References in this prospectus
to “we,” “us,” “our” and “Company” refer to Hepion
Pharmaceuticals, Inc. and its consolidated
subsidiaries.
Business Overview
We are a biopharmaceutical company
headquartered in Edison, New Jersey, focused on the development of
pleiotropic drug therapy for treatment of chronic liver disease.
This therapeutic approach targets fibrosis and hepatocellular
carcinoma (“HCC”) associated with non-alcoholic steatohepatitis
(“NASH”), viral hepatitis, and other liver diseases. Our
cyclophilin inhibitor, CRV431, is being developed to offer benefits
to address these multiple complex pathologies. CRV431 is a
cyclophilin inhibitor that targets multiple biochemical pathways
involved in the progression of liver disease. Preclinical studies
with CRV431 in NASH models demonstrated consistent reductions in
liver inflammation, fibrosis, and cancerous tumors. CRV431
additionally shows antiviral activity towards hepatitis B, C, and D
viruses which also trigger liver disease.
We have completed a Phase 1 program
with CRV431 demonstrating safety, tolerability, and
pharmacokinetics (PK). Our program consisted of three different
clinical trials with CRV431, administered orally once daily, that
included: 1) a Single Ascending Dose (SAD) study; 2) a Multiple
Ascending Dose (MAD) study; and 3) a Drug-Drug Interaction (DDI)
study. The SAD, MAD, and DDI studies were comprised of 32, 25, and
18 healthy subjects, respectively. Additionally, in the SAD study,
8 of the 32 subjects received placebo (24 received
CRV431).
CRV431 appeared to be well-tolerated
in the Phase 1 program, and there were no serious adverse effects
(SAEs). The few adverse effects (AEs) observed were mild to
moderate and mostly unrelated to study drug. The PK profile of each
subject was characterized and CRV431 blood exposures were similar
to those needed to elicit efficacy in the preclinical
studies.
We are currently conducting a Phase
2a study in NASH patients with fibrosis scores of F2 and F3. The
first dosing cohort of 75 mg CRV431 once daily orally is
underway.
NASH is the form of liver disease
that is triggered by what has come to be known as the “Western
diet”, characterized especially by high-fat, high-sugar, and
processed foods. Among the effects of a prolonged Western diet is
fat accumulation in liver cells (steatosis) which is described
as non-alcoholic fatty liver disease (“NAFLD”)
and can predispose cells to injury. NAFLD may evolve into NASH when
the fatty liver begins to progress through stages of cell injury,
inflammation, fibrosis, and carcinogenesis. People who develop NASH
often have additional predisposing conditions such as diabetes and
hypertension, but the exact biochemical events that trigger and
maintain the progression are not well known. Many people in the
early stages of disease do not have significant symptoms and
therefore do not know that they have it. NASH becomes evident and a
major concern when the liver becomes fibrotic and puts the
individual at increased risk of developing cirrhosis and other
complications. Individuals with advanced liver fibrosis have
significantly higher risk of developing liver cancer, although
cancer may also arise in some patients before significant hepatitis
or fibrosis. NASH is increasing worldwide at an alarming rate due
to the spread of the Western diet, obesity, and other related
conditions. Approximately 4-5% of the global population is
estimated to have NASH, and that proportion is higher in the USA.
It is predicted that NASH will become the leading reason for
individuals requiring a liver transplant in the USA as early as
2020. Considering the serious outcomes linked to advancing NASH,
the economic and social burden of the disease is enormous. There
are no simple blood tests to diagnose or track the progression of
NASH, and no drugs are approved to specifically treat the
disease.
HCC is the major type of liver
cancer, accounting for 85-90% of all cases. NASH, hepatitis virus
infection, and alcohol consumption all are major causes of HCC.
Globally, over 700,000 people die each year from liver cancer which
is second only to lung cancer among all cancer-related deaths.
The high mortality is due to the fact that only around half of all
people who develop HCC (in developed countries) receive the
diagnosis early enough to have an opportunity for therapeutic
intervention. Additionally, recurrence rates are high, and current
treatment options remain limited.
HCC is a type of cancer in which the
tissue microenvironment plays a major role in its development. In
most cases HCC is preceded by significant, long-term damage to
liver cells, inflammation and fibrosis. One-third of people with
cirrhosis, a very advanced stage of liver disease, will eventually
progress to HCC. The chronic injury to the liver leads to many
genetic mutations that eventually lead to transformation of cells
and formation of tumors. The noxious tissue microenvironment also
promotes cancer by altering the function of immune cells and
endothelial cells which form tumor-supporting blood vessels.
These various events underscore the
importance of halting liver injury and scarring as early and
effectively as possible to prevent cancer development.
Viral hepatitis may be linked to one
or more viruses including hepatitis A, B, C, D, or E. Hepatitis B
virus (“HBV”) is one of many hepatitis viruses that selectively
infect human liver cells and can establish persistent infections
under certain conditions. Chronic infections, especially by HBV,
HCV, and HDV, cause progressive liver inflammation, fibrosis,
cirrhosis, and cancer. Collectively, these infections represent one
of the 3 major triggers of progressive liver disease (NAFLD/NASH
and alcohol being the others).
An HBV vaccine is available that, if
administered prior to HBV infection, assists the
body in neutralizing the virus and blocking infection. However,
vaccination is not efficacious for people who are already infected
with HBV, and the vaccine has not been historically available to
everyone. As a result, an estimated 240 million people worldwide
have chronic HBV infection. Anti-HBV medications are used widely by
chronically infected individuals but usually are only effective in
decreasing viral replication and viremia (virus in the blood), and
NOT in eradicating HBV from the liver. This is because HBV, unlike
HCV, has evolved clever ways of persisting in liver cells and
evading the immune system. Thus, despite vaccines and anti-viral
medications, chronic HBV infection remains a huge global health
problem. Chronic HBV infection is the leading cause of
hepatocellular carcinoma, which kills around 350,000 people per
year. A similar number of people die each year from cirrhosis and
other complications arising from HBV.
We are developing CRV431 as our lead
molecule. CRV431 is a cyclophilin inhibitor that targets specific
isomerases that play an important role in protein folding in health
and in disease. To date, in
vitro and/or in vivo studies have
demonstrated reductions in HBV DNA, HBsAg, HBeAg, inhibition of
virus uptake (NTCP transport inhibition), and stimulation of innate
immunity. Importantly, in vivo studies in a NASH
model of fibrosis and HCC have repeatedly demonstrated CRV431
reduces fibrosis scores and overall liver tumor burden. Hence,
CRV431 is a pleiotropic molecule that may not only treat liver
disease but may also serve to reduce important risk factors (e.g.,
HBV) for developing the disease.
CRV431
CRV431 is a novel drug candidate
designed to target a class of proteins called cyclophilins, of
which there are many isoforms. Cyclophilins play a role in health
and in the pathogenesis of certain diseases and are known as
peptidyl prolyl isomerases. The isomerase activity plays an
important role in several biological processes including, for
example, folding of proteins to confer certain 3-dimensional
configurations. Additionally, specific host cyclophilins
(e.g., cyclophilin A, B, C, D) play a role in the
pathogenesis of many diseases, including liver disease and viral
hepatitis.
Cyclophilins are pleiotropic enzymes
that play a role in injury and steatosis through mechanisms
including cell death occurring through mitochondrial pore
permeability (cyclophilin D). Inhibition of cyclophilin D,
therefore, may play an important role in protection from cell
death. Cyclophilin A binding to CD147 is known to play a role in
inflammation, cyclophilin B plays a role in fibrosis through
collagen production, and cyclophilins also play a role in cirrhosis
and cancer (e.g., cell proliferation and metastasis). Cyclophilin
inhibition with CRV431, therefore, may play an important role in
reducing liver disease.
To date, we have completed eight
separate preclinical animal efficacy studies of CRV431 to assess
antifibrotic activity. Each of these eight studies were conducted
by independent laboratory collaborations at The Scripps Research
Institute (San Diego, CA), SMC Corporation (Tokyo, Japan), and
Physiogenex S.A.S. (France), Each of these studies demonstrated
consistent and significant reductions in fibrosis in mice and rats.
CRV431 was also tested in Precision Cut Liver Slices and in
Precision Cut Lung Slices in ex plants from human donors.
Again, CRV431 demonstrated an antifibrotic effect that was
consistent with the animal study findings. These studies provide
support of advancing CRV431 into clinical trials for NASH, and
potentially additional indications where fibrosis plays a
role.
Important risk factors for
development of liver disease include viral hepatitis (HBV, HCV,
HDV), alcohol, and non-alcoholic fatty liver disease and the more
aggressive form called non-alcoholic steatohepatitis. The life
cycle of certain viruses, including for example, HBV, HIV, and
hepatitis C virus (“HCV”) infections are dependent on host proteins
(cyclophilins) for the role they play in the virus life cycle and
propagation of the virus. CRV431 has been developed to inhibit the
role of host cyclophilins and therefore interfere in viral
propagation. CRV431 does not directly target the virus and, as
such, should be less susceptible to drug resistance, borne from
viral mutations.
Data in various cell lines of either
transfected or infected HBV demonstrates nanomolar efficacy (EC50
values) and micromolar toxicity (CC50 values). The selective index
(“SI”), therefore, is wide and suggests that CRV431 presents a
viable clinical drug candidate for the treatment of viral
infections, including HBV. Additional testing in a transgenic mouse
model of HBV indicated that CRV431 reduced HBV DNA in the liver and
HBsAg in serum. CRV431 is orally active and appears to be well
tolerated.
On May 10, 2018, we submitted an Investigational New Drug
Application (“IND”) to the U.S. Food and Drug Administration
(“FDA”) to support initiation of our CRV431 HBV clinical
development program in the United States and received approval in
June 2018. We completed the first segment of our Phase 1
clinical activities for CRV431 in October 2018 wherein we
reached a major clinical milestone of positive data from a Phase I
trial of CRV431 in humans. This achievement triggered the first
milestone payment, as stated in the Merger Agreement for the
acquisition of Ciclofilin Pharmaceuticals, Inc. (“Ciclofilin”)
and we paid a related milestone payment of approximately $346,000
to Aurinia Pharmaceuticals, Inc. ("Aurinia") and $654,000 to the
former Ciclofilin shareholders along with the issuance of 1,439
shares of our common stock with a fair value of $55,398,
representing 2.5% of our issued and outstanding common stock as of
June, 2016, to the former Ciclofilin shareholders. Our CEO is a
former Ciclofilin shareholder and received approximately $274,000
and 603 shares of common stock and Petrus Wijngaard, a director of
our company, received $2,805 and 6 shares of common stock.
Additional milestone payments could potentially be payable to the
former Ciclofilin shareholders pursuant to the Ciclofilin Merger
Agreement as follows: (i) upon receipt of Phase II positive data
from a proof of concept clinical trial of CRV431 in humans - 4,317
shares of common stock and $3,000,000, (ii) upon initiation of a
Phase III trial of CRV431 - $5,000,000, and (iii) upon acceptance
by the FDA of a new drug application for CRV431 - $8,000,000 . In
addition, on February 14, 2014, Ciclofilin had entered into a
Purchase and Sale Agreement to acquire Aurinia’s entire interest in
CRV431. This agreement contains future milestone payments payable
by us based on clinical and marketing milestones of up to CAD $2.45
million. The milestone payments payable to the former Ciclofilin
shareholders will be subject to offset by certain of the clinical
and marketing milestone payments payable to Aurinia as follows: (a)
the payments to the former Ciclofilin shareholders pursuant to (ii)
above would be offset by payment to Aurinia of CAD $450,000, and
(b) the payments to the former Ciclofilin shareholders pursuant to
(iii) above would be subject to offset by payment to Aurinia of up
to CAD $2,000,000. In addition to the above clinical and milestone
payments, the Aurinia Agreement provides for the following
additional contingent payment obligations: (x) a royalty of 2.5% on
net sales of CRV431 which is uncapped, (y) a royalty of 5% on
license revenue from CRV431 and (z) a payment equal to 30% of the
proceeds from a Liquidity Event (as defined in the Purchase and
Sale Agreement) with respect to Ciclofilin, of which approximately
$150,000 plus interest will be paid to Aurinia upon the closing of
this offering. The maximum obligation under both (y) and (z) is CAD
$5,000,000.
On June 17, 2019, we submitted an IND to the FDA to support
initiation of our CRV431 NASH clinical development program in the
United States and received approval in July 2019. We completed
dosing of CRV431 in our MAD clinical trial in September, 2020.
ARTIFICAL INTELLIGENCE (AI)
We have created a proprietary AI called, “AI-POWRTM to
optimize the outcomes of our current clinical programs and to
potentially identify novel indications for CRV431 and possibly
identify new targets and new drug molecules to broaden our
pipeline.
AI-POWR™ is our acronym for Artificial
Intelligence - Precision Medicine;
Omics that include genomics, proteomics,
metabolomics, transcriptomics, and lipidomics; World
database access; and Response and clinical outcomes.
AI-POWR™ allows for the selection of novel drug targets,
biomarkers, and appropriate patient populations. AI-POWR™ is used
to identify responders from big data sources using our multi-omics
approach, while modelling inputs and scenarios to increase response
rates. The components of AI-POWR™ include access to publicly
available databases, and in-house genomic and multi-omic big data,
processed via machine learning algorithms. AI outputs allow for
improved response outcomes through enhanced patient selection,
biomarker selection and drug target selection. We believe AI
outputs will help identify responders a priori and reduce
the need for large sample sizes through study design
enrichment.
We intend to use AI-POWR™ to help identify which patients will best
respond to CRV431 for treatment of NASH patients, currently in a
Phase 2a clinical trial. It is anticipated that applying this
proprietary platform to our drug development program will
ultimately save time, resources and money. In so doing, we believe
that AI-POWR™ is a risk-mitigation strategy that should reap
benefits all the way through from clinical trials to
commercialization.
We believe that NASH is a very heterogenous disease and we need to
have a better understanding of interactions between changes to
proteins, genes, lipids, and metabolites, to name a few, induced by
both drugs and disease. All of this is further complicated by
variable drug concentrations, patient traits and temporal factors.
AI-POWR™ is designed to address many of these typical challenges,
as we believe we can use our proprietary platform to shorten
development timelines and increase the delta between placebo and
treatment groups. AI-POWR™ will be used to drive our ongoing Phase
2a NASH program and identify additional potential indications for
CRV431 to expand our footprint in the cyclophilin inhibition
therapeutic space.
Recent Developments
On July 30, 2020, our stockholders approved an amendment to our
2013 Equity Incentive Plan (the "Plan"), increasing the number of
shares of common stock issuable under the Plan to 2,500,000 from
40,535. As of September 30, 2020, 2,499,473 shares of our common
stock are issuable upon exercise of outstanding options under the
Plan and 527 shares of common stock are reserved for future
issuance under the Plan.
Risks Associated with our Business
Our business is subject to numerous risks and uncertainties,
including those highlighted and incorporated by reference in the
section entitled “Risk Factors” immediately following this
prospectus summary. These risks include, but are not limited to,
the following:
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• |
Our product candidate, CRV431, is in the early stages of
clinical development and its commercial viability remains subject
to the successful outcome of current and future clinical trials,
regulatory approvals and the risks generally inherent in the
development of pharmaceutical product candidates. If we are unable
to successfully advance or develop or partner our product
candidate, we may be delayed or precluded further development or
regulatory approval. |
|
• |
A pandemic,
epidemic or outbreak of an infectious disease, such as COVID-19,
may materially and adversely affect our business and operations.
The Company cannot estimate the length or gravity of the impact of
the COVID-19 outbreak at this time, but if the pandemic continues,
it may have a material adverse effect on the Company’s results of
future operations, financial position, liquidity, and capital
resources, and those of the third parties on which the Company
relies in fiscal year 2020. |
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• |
We have
incurred losses since inception, anticipate that we will incur
continued losses for the foreseeable future indicating the
possibility that we may not be able to operate in the future. |
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• |
We will require
substantial additional funding which may not be available to us on
acceptable terms, or at all. If we fail to raise the necessary
additional capital, we may be unable to complete the development
and commercialization of our product candidate, or continue our
development programs. |
|
• |
If we fail to
comply with the continued listing requirements of The Nasdaq
Capital Market, our common stock may be delisted and the price of
our common stock and our ability to access the capital markets
could be negatively impacted. |
|
• |
Our product
candidate and any future product candidates may exhibit undesirable
side effects when used alone or in combination with other approved
pharmaceutical products or investigational new drugs, which may
delay or preclude further development or regulatory approval, or
limit their use if approved. |
|
• |
If the results
of preclinical studies or clinical trials for our product
candidate, including those that are subject to existing or future
license or collaboration agreements, are unfavorable or delayed, we
could be delayed or precluded from the further development or
commercialization of our product candidate, which could materially
harm our business. |
|
• |
Clinical trials
involve a lengthy and expensive process with an uncertain outcome,
and results of earlier studies and trials may not be predictive of
future trial results. |
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• |
The regulatory
approval processes of the FDA and comparable foreign authorities
are lengthy, time consuming and inherently unpredictable, and if we
are ultimately unable to obtain regulatory approval for our product
candidate, our business will be substantially harmed. |
|
• |
We currently
have no sales and marketing organization. If we are unable to
establish a direct sales force in the United States to promote our
products, the commercial opportunity for our products may be
diminished. |
|
• |
We may not be
able to manufacture our product candidate in commercial quantities,
which would prevent us from commercializing our product
candidate. |
|
• |
Our product
candidate, if approved for sale, may not gain acceptance among
physicians, patients and the medical community, thereby limiting
our potential to generate revenues. |
|
• |
You will
experience immediate and substantial dilution in the book value per
share of the common stock you purchase. |
|
• |
Management will
have broad discretion as to the use of proceeds from this offering
and might not use them effectively. |
Corporate History and Information
We were incorporated in Delaware on May 15, 2013 for the
purpose of holding certain FV-100 assets of Synergy
Pharmaceuticals Inc., or Synergy. We were a majority-owned
subsidiary of Synergy Pharmaceuticals Inc. (Synergy) until
February 18, 2014, the date Synergy completed the spinout of
our shares of common stock. On July 18, 2019, we filed a
certificate of amendment to our certificate of incorporation to
change the Company’s name from “ContraVir Pharmaceuticals, Inc.” to
“Hepion Pharmaceuticals, Inc.” The name change became effective as
of July 18, 2019.
Our principal executive offices are located at 399 Thornall Street,
First Floor, Edison, New Jersey 08837. Our telephone number is
(732) 902-4000 and our website address is
www.hepionpharma.com. The information on our website is not a part
of, and should not be construed as being incorporated by reference
into, this registration statement or the accompanying
prospectus.
THE OFFERING
Common
stock offered |
|
shares. |
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Over-allotment
option |
|
We
have granted a 45-day option to the representative of the
underwriters to purchase up
to additional
shares of common stock solely to cover over-allotments, if
any, at the public offering price less underwriting
discounts and commissions. |
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Common stock to be outstanding after this
offering (1)
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|
shares
of common stock (or
shares
of common stock if the underwriters exercise in full their option
to purchase additional shares of common stock). |
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Use
of proceeds |
|
We estimate that the net proceeds to us from this offering from the
sale of the shares of our common stock will be approximately $
million, or approximately $ million if the underwriters
exercise their option to
purchase additional shares in full, at the assumed public offering
price of $ , the closing price of our common stock as reported on
The Nasdaq Capital Market on , 2020, and after deducting
underwriting discounts and commissions and offering expenses
payable by us.
We intend to use the net proceeds of this offering to
fund our research and development activities and general corporate
purposes, including approximately $150,000 plus interest for a
milestone payment, working capital, operating expenses and capital
expenditures. We may use the net proceeds from this offering to
fund possible acquisitions of other companies, products or
technologies, though no such acquisitions are currently
contemplated. See “Use of Proceeds.”
|
Risk
factors |
|
Investing
in our securities involves a high degree of risk. See
“Risk Factors” beginning on page 6 of this prospectus and the risk
factors included in our Form 10-K for the year ended December
31, 2019, which are incorporated by reference into this
prospectus, for a discussion of factors to consider carefully
before deciding to invest in shares of our common stock in this
offering. |
|
|
|
Nasdaq
symbol |
|
Our
common stock is listed on The Nasdaq Capital Market under the
symbol “HEPA.” |
(1) |
Based on 9,025,061 shares of common stock outstanding as of
June 30, 2020 and excludes: |
|
• |
1,402,771 shares of our common stock issuable upon exercise of
outstanding options at a weighted average price of $7.76 per
share; |
|
• |
2,536,566 shares of our common stock issuable upon exercise of
outstanding warrants with a weighted-average exercise price of
$19.35 per share; |
|
• |
3,184 shares of our common stock issuable upon conversion of
outstanding shares of Series A Convertible Preferred
Stock; |
|
• |
16,839 shares of our common stock issuable upon conversion of
outstanding shares of Series C Convertible Preferred Stock;
and |
|
• |
shares
of our common stock issuable upon exercise of the warrant to be
issued to the representative in connection with this offering. |
RISK FACTORS
An investment in our securities involves a high degree of risk.
You should carefully consider the risk factors contained in our
periodic reports filed with the SEC, including our Annual Report on Form 10-K for
the year ended December 31, 2019 and all of our quarterly
reports on Form 10-Q, which are incorporated by reference into
this prospectus. Before deciding to invest in our securities, you
should carefully consider these risks, as well as other information
we include or incorporate by reference in this prospectus.
If any of the events described in these risk factors actually
occurs, or if additional risks and uncertainties that are not
presently known to us or that we currently deem immaterial later
materialize, then our business, prospects, results of operations
and financial condition could be materially adversely affected. In
that event, the trading price of our securities could decline, and
you may lose all or part of your investment in our securities. The
risks discussed below include forward-looking statements, and our
actual results may differ substantially from those discussed in
these forward-looking statements. See “Cautionary Statement
Regarding Forward-Looking Statements.”
Risks Related to our Business
The following items
supplement the risks related to our business previously reported in
Part 1, “Item 1A. Risk Factors – Risks Related to Our Business” of
our Annual Report on Form 10-K for the
year ended December 31, 2019:
Our
approach to the discovery and development of product candidates
based on AI-POWR™ is novel and unproven,
and we do not know whether we will be able to develop any products
of commercial value.
We intend
to leverage AI-POWR™ to potentially
identify novel indications for CRV431 and possibly identify new
targets and new drug molecules to broaden our pipeline for patients whose
diseases have not been adequately addressed to date by other
approaches and to design and conduct efficient clinical trials with
a higher likelihood of success. While we believe that
applying AI-POWR™ to create medicines
for defined patient populations may potentially enable drug
research and clinical development that is more efficient than
conventional drug research and development, our approach is both
novel and unproven. Because our approach is both novel and
unproven, the cost and time needed to develop our product
candidates is difficult to predict, and our efforts may not result
in the discovery and development of commercially viable medicines.
We may also be incorrect about the effects of our product
candidates on the diseases of our defined patient populations,
which may limit the utility of our approach or the perception of
the utility of our approach. Furthermore, our estimates of our
defined patient populations available for study and treatment may
be lower than expected, which could adversely affect our ability to
conduct clinical trials and may also adversely affect the size of
any market for medicines we may successfully commercialize. Our
approach may not result in time savings, higher success rates or
reduced costs as we expect it to, and if not, we may not attract
collaborators or develop new drugs as quickly or cost effectively
as expected and therefore we may not be able to commercialize our
approach as originally expected.
AI-POWR™may fail to
help us discover and develop additional potential product
candidates.
Any
drug discovery that we are conducting using AI-POWR™
may not be
successful in identifying compounds that have commercial value or
therapeutic utility. AI-POWR™ may initially show
promise in identifying potential product candidates, yet fail to
yield viable product candidates for clinical development or
commercialization for a number of reasons, including:
|
· |
research programs to
identify new product candidates will require substantial technical,
financial and human resources, and we may be unsuccessful in our
efforts to identify new product candidates. If we are unable to
identify suitable additional compounds for preclinical and clinical
development, our ability to develop product candidates and obtain
product revenues in future periods could be compromised, which
could result in significant harm to our financial position and
adversely impact our stock price; |
|
· |
compounds found
through AI-POWR™ may not demonstrate
efficacy, safety or tolerability; |
|
· |
potential product
candidates may, on further study, be shown to have harmful side
effects or other characteristics that indicate that they are
unlikely to receive marketing approval and achieve market
acceptance; |
|
|
|
|
· |
competitors may
develop alternative therapies that render our potential product
candidates non-competitive or less attractive; or |
|
· |
a
potential product candidate may not be capable of being produced at
an acceptable cost. |
Risks Related to this Offering
Management will have broad discretion as to the use of
proceeds from this offering and might not use them
effectively.
Our management will have broad discretion as to the application of
the net proceeds from this offering and our stockholders will not
have the opportunity as part of their investment decisions to
assess whether the net proceeds are being used appropriately. You
might not agree with our decisions, and our use of the proceeds
might not yield any return on your investment. Because of the
number and variability of factors that will determine our use of
the net proceeds from this offering, their ultimate use may vary
substantially from their currently intended use. Our failure to
apply the net proceeds of this offering effectively could
compromise our ability to pursue our growth strategy and we might
not be able to yield a significant return, if any, in our
investment of these net proceeds. You will not have the opportunity
to influence our decisions on how to use our net proceeds from this
offering.
Investors in this offering will experience immediate and
substantial dilution and may experience further dilution in the
future.
The
offering price per share of our common stock being offered will be
higher than the net tangible book value per share of our common
stock. Therefore, if you purchase shares of common stock in this
offering, you will incur immediate and substantial dilution in the
as adjusted net tangible book value per share of common stock from
the price you pay for the common stock. For a further description
of the dilution that investors in this offering will experience,
see “Dilution”.
Furthermore,
we expect that we will seek to raise additional capital from time
to time in the future. Such financings may involve the issuance of
equity and/or securities convertible into or exercisable or
exchangeable for our equity securities. In addition,
investors in this offering will be subject to increased dilution
upon the exercise of outstanding stock options or warrants or
conversion of outstanding preferred stock. We also expect to
continue to utilize equity-based compensation which would further
dilute investors. We have in the past issued, and could in the
future issue, securities with anti-dilution features which if
triggered could result in further dilution to our stockholders.
If we fail to comply with the continued listing requirements
of The Nasdaq Capital Market, our common stock may be delisted and
the price of our common stock and our ability to access the capital
markets could be negatively impacted.
A delisting of our common stock from The Nasdaq Capital Market
could materially reduce the liquidity of our common stock and
result in a corresponding material reduction in the price of our
common stock. In addition, delisting could harm our ability to
raise capital through alternative financing sources on terms
acceptable to us, or at all, and may result in the potential loss
of confidence by investors, employees and fewer business
development opportunities.
A large number of shares issued in this offering may be sold
in the market following this offering, which may depress the market
price of our common stock.
A large number of shares issued in this offering may be sold in the
market following this offering, which may depress the market price
of our common stock. Sales of a substantial number of shares of our
common stock in the public market following this offering could
cause the market price of our common stock to decline. If there are
more shares of common stock offered for sale than buyers are
willing to purchase, then the market price of our common stock may
decline to a market price at which buyers are willing to purchase
the offered shares of common stock and sellers remain willing to
sell the shares. All of the shares of common stock issued in the
offering will be freely tradable without restriction or further
registration under the Securities Act.
We have not paid dividends in the past and have no immediate
plans to pay dividends.
We plan to reinvest all of our earnings, to the extent we have
earnings, in order to further develop our product candidate and to
cover operating costs. We do not plan to pay any cash dividends
with respect to our securities in the foreseeable future. We cannot
assure you that we would, at any time, generate sufficient surplus
cash that would be available for distribution to the holders of our
common stock as a dividend. Therefore, you should not expect to
receive cash dividends on the common stock we are offering.
CAUTIONARY STATEMENT REGARDING
FORWARD-LOOKING STATEMENTS
This prospectus and the documents we incorporate by reference in
this prospectus contain forward-looking statements within the
meaning of Section 27A of the Securities Act, and Section 21E of
the Exchange Act, and may involve material risks, assumptions and
uncertainties. Statements that are not purely historical should be
considered forward-looking statements. Often they can be identified
by the use of forward-looking words and phrases, such as “may,”
“will,” “believe,” “anticipate,” “expect,” “should,” “optimistic”
or “continue,” “estimate,” “intend,” “plan,” “would,” “could,”
“guidance,” “potential,” “opportunity,” “project,” “forecast,”
“confident,” “projections,” “schedule,” “designed,” “future” and
the like. These forward-looking statements reflect our current
expectations and projections about future events and financial
trends that we believe may affect our business, financial condition
and results of operations. These forward-looking statements are
subject to a number of risks, uncertainties and assumptions
described under the section entitled “Risk Factors.”
These statements are not guarantees of future performance and
involve risks and uncertainties that are difficult to predict or
are beyond our control. A number of important factors could cause
actual outcomes and results to differ materially from those
expressed in these forward-looking statements. Consequently,
readers should not place undue reliance on such forward-looking
statements. In addition, these forward-looking statements relate to
the date on which they are made.
The forward-looking statements reflect our current expectations and
are based on information currently available to us and on
assumptions we believe to be reasonable. Forward-looking
information is subject to known and unknown risks, uncertainties
and other factors that may cause our actual results, activities,
performance or achievements to be materially different from that
expressed or implied by such forward-looking statements. Some of
the risks, uncertainties, and other factors that could cause actual
results to differ materially from estimates or projections
contained in the forward-looking statements include, but are not
limited to:
|
• |
The impact of COVID-19 on our operations; |
|
• |
Our ability to compete with larger, better financed
pharmaceutical companies; |
|
• |
Our uncertainty of developing marketable products; |
|
• |
Our ability to develop and commercialize our products; |
|
• |
Our ability to obtain regulatory approvals; |
|
• |
Our ability to maintain and protect intellectual property
rights; |
|
• |
The inability to raise additional future financing and lack of
financial and other resources; |
|
• |
Our ability to control product development costs; |
|
• |
We may not be able to attract and retain key employees; |
|
• |
We may not be able to compete effectively; |
|
• |
We may not be able enter into new strategic
collaborations; |
|
• |
Changes in government regulation affecting product candidates
could increase our development costs; |
|
• |
Our involvement in patent and other intellectual property
litigation could be expensive and could divert management’s
attention; |
|
• |
The possibility that there will be no market acceptance for our
products; and |
|
• |
Changes in third-party reimbursement policies could adversely
affect potential future sales of any of our products that are
approved for marketing. |
Although we have attempted to identify important factors that could
cause actual actions, events or results to differ materially from
those described in forward-looking information, there may be other
factors that cause actions, events or results to differ from those
anticipated, estimated or intended. Other than as required by law,
we do not assume any obligation to update any forward-looking
information, whether as a result of new information, future events
or results or otherwise.
You should also read the matters described in “Risk Factors” and
the other cautionary statements made in this prospectus and the
documents incorporated by reference into this prospectus. The
forward-looking statements in this prospectus and the documents
incorporated by reference into this prospectus may not prove to be
accurate and therefore you are encouraged not to place undue
reliance on forward-looking statements. You should read this
prospectus and the documents incorporated by reference into this
prospectus completely.
This prospectus and the documents incorporated by reference into
this prospectus also include estimates and other statistical data
made by independent parties and by us relating to market size and
growth and other data about our industry. This data involves a
number of assumptions and limitations, and you are cautioned not to
give undue weight to such estimates. In addition, projections,
assumptions and estimates of our future performance and the future
performance of the markets in which we operate are necessarily
subject to a high degree of uncertainty and risk.
USE OF PROCEEDS
We estimate that the net proceeds to us from this offering from the
sale of the shares of our common stock will be approximately $
million, or approximately
$
million if the underwriters exercise their option to purchase
additional shares in full, at the assumed public offering price of
$ , the
closing price of our common stock as reported on the Nasdaq Capital
Market on , 2020, and after deducting underwriting discounts and
commissions and offering expenses payable by us.
We
intend to use the net proceeds from this offering to fund our
research and development activities and general corporate purposes,
including approximately $150,000 plus interest for a milestone
payment, working capital, operating expenses and capital
expenditures. We may use the net proceeds from this offering to
fund possible acquisitions of other companies, products or
technologies, though no such acquisitions are currently
contemplated.This expected use of our net proceeds from this
offering represents our intentions based upon our current plans and
business conditions, which could change in the future as our plans
and business conditions evolve. The amounts and timing of our
actual expenditures may vary significantly depending on numerous
factors, including the progress of our drug candidate development,
the status of and results from clinical trials, as well as any
collaborations that we may enter into with third parties for
our drug candidate, and any unforeseen cash needs.
As a result, our management will retain broad discretion over the
allocation of the net proceeds from this offering, and investors
will be relying on the judgment of our management regarding the
application of the net proceeds from this offering. The timing and
amount of our actual expenditures will be based on many factors,
including cash flows from operations and the anticipated growth of
our business.
DILUTION
If
you purchase securities in this offering, your interest will be
diluted to the extent of the difference between the public offering
price and the net tangible book value per share of our common stock
after this offering. Our net tangible book value as of June 30,
2020 was $13,231,154 million or $1.47 per share of common stock
based on 9,025,061 shares of our common stock outstanding as
of that date. “Net tangible book value” is total assets minus the
sum of liabilities and intangible assets. “Net tangible book value
per share” is net tangible book value divided by the total number
of shares of common stock outstanding.
After giving effect to the sale by us in this offering
of
shares of common stock at an assumed offering price
of
per share, which was the last reported sale price of our common
stock on the Nasdaq Capital Market on
,
2020, and after deducting the estimated underwriting discounts and
commissions and estimated offering expenses payable by us, our as
adjusted net tangible book value as of June 30, 2020 would have
been approximately
$
million, or
$
per share of common stock. This amount represents an immediate
increase in net tangible book value of
$
per share to existing stockholders and an immediate dilution of
$
per share to purchasers in this offering.
The following table illustrates the dilution:
Assumed public offering
price per share |
|
|
$ |
|
Net tangible book value
per share as of June 30, 2020 |
$ |
1.47 |
|
|
Assumed increase in net
tangible book value per share attributable to this
offering |
$ |
|
|
|
Assumed as
adjusted net tangible book value per share as of June 30, 2020
after giving effect to this offering |
|
|
$ |
|
Assumed dilution per
share to new investors |
|
|
$ |
|
The actual price at which shares are sold in this offering and the
actual amount of underwriting discounts and commissions and
offering expenses payable by us may be lesser or greater than the
assumed amounts reflected in the table above.
The dilution information set forth in the table above is
illustrative only and will be adjusted based on the actual public
offering price and other terms of this offering determined at
pricing.
The above table is based on 9,025,061 shares of common stock
outstanding as of June 30, 2020, does not give effect to any
exercise of the underwriters’ option to purchase additional shares
and excludes:
|
• |
1,402,771 shares of our common stock issuable upon exercise of
outstanding options at a weighted average price of $7.76 per
share; |
|
• |
2,536,566 shares of our common stock issuable upon exercise of
outstanding warrants with a weighted-average exercise price of
$19.35 per share; |
|
• |
3,184 shares of our common stock issuable upon conversion of
outstanding shares of Series A Convertible Preferred
Stock; |
|
• |
16,839 shares of our common stock issuable upon conversion of
outstanding shares of Series C Convertible Preferred Stock;
and |
|
• |
shares
of our common stock issuable upon exercise of the warrant to be
issued to the representative in connection with this offering. |
If we issue any additional shares in connection with outstanding
options or warrants or issue shares upon conversion of outstanding
preferred stock there will be additional dilution. In addition, we
may choose to raise additional capital. To the extent that
additional capital is raised through the sale of equity or
convertible debt securities, the issuance of these securities could
result in further dilution to our stockholders.
CAPITALIZATION
The following table sets forth our cash and our capitalization as
of June 30, 2020 on:
|
• |
an as adjusted basis to give effect to this offering (assuming
no exercise of the underwriters’ option to purchase additional
shares) at an assumed offering price of
$
per share, which was the last reported sale price of our common
stock on the Nasdaq Capital Market on
,
2020, after deducting the estimated underwriting discounts and
commissions and estimated offering expenses payable by us. |
The following data is qualified in its entirety by, and should be
read in conjunction with, our unaudited condensed consolidated
financial statements and notes thereto incorporated by reference in
this prospectus. The as adjusted information set forth in
the table below is illustrative only and will be adjusted based on
the actual public offering price and other terms of this offering
determined at pricing.
|
|
As of June 30, 2020 |
|
|
|
Actual |
|
|
As adjusted |
|
Cash |
|
$ |
17,561,813 |
|
|
|
|
|
Total long-term
debt |
|
$ |
176,585 |
|
|
|
|
|
Stockholders’
equity: |
|
|
|
|
|
|
|
|
Preferred Stock, stated value $10.00 per share; 85,581 shares of
Series A Convertible Preferred Stock issued and
outstanding |
|
|
855,808 |
|
|
|
|
|
Preferred Stock, stated value $1,000; 1,827 shares of
Series C Convertible Preferred Stock issued and
outstanding |
|
|
861,033 |
|
|
|
|
|
Common Stock, par value $0.0001; 120,000,000 shares authorized;
9,025,061 shares issued and outstanding, actual;
shares
issued and outstanding, as adjusted |
|
|
901 |
|
|
|
|
|
Additional paid-in capital |
|
|
108,923,663 |
|
|
|
|
|
Accumulated deficit |
|
|
(92,349,327 |
) |
|
|
|
|
Total stockholders’ equity |
|
|
18,292,078 |
|
|
|
|
|
Total capitalization |
|
$ |
18,468,663 |
|
|
|
|
|
The
capitalization table above is based on the number of shares
outstanding as of June 30, 2020, does not give effect to any
exercise of the underwriters’ option to purchase additional
shares. The number of shares of our common stock that
will be outstanding after this offering is based on 9,025,061shares
of common stock outstanding as of June 30, 2020 and excludes:
|
• |
1,402,771 shares of our common stock issuable upon exercise of
outstanding options at a weighted average price of $7.76 per
share; |
|
• |
2,536,566 shares of our common stock issuable upon exercise of
outstanding warrants with a weighted-average exercise price of
$19.35 per share; |
|
• |
3,184 shares of our common stock issuable upon conversion of
outstanding shares of Series A Convertible Preferred
Stock; |
|
• |
16,839 shares of our common stock issuable upon conversion of
outstanding shares of Series C Convertible Preferred Stock;
and |
|
• |
shares
of our common stock issuable upon exercise of the warrant to be
issued to the representative in connection with this offering. |
DESCRIPTION OF THE SECURITIES WE ARE
OFFERING
General
We are authorized to issue up to 120,000,000 shares of common
stock, $0.0001 par value per share, and 20,000,000 shares of
preferred stock, $0.0001 par value per share.
As of June 30, 2020, there were 9,025,061 shares of our common
stock issued and outstanding, 85,581 shares of Series A
convertible preferred stock outstanding, and 1,827 shares of
Series C convertible preferred stock outstanding. As of June
30, 2020, we had outstanding warrants to purchase an aggregate of
2,536,566 shares of our common stock at an average weighted
exercise price of $19.35 per share.
Common Stock
Holders of common stock are entitled to receive ratably dividends
out of funds legally available, if and when declared from time to
time by our Board. We have never paid any cash dividends on our
common stock and our Board does not anticipate that we will pay
cash dividends in the foreseeable future. The future payment of
dividends, if any, on our common stock is within the discretion of
the Board and will depend upon earnings, capital requirements,
financial condition and other relevant factors. Holders of common
stock are entitled to one vote for each share held on each matter
to be voted on by stockholders. There is no cumulative voting in
the election of directors. In the event of liquidation, dissolution
or winding up of the affairs of us, holders of common stock are to
share in all assets remaining after the payment of liabilities and
any preferential distributions payable to preferred stockholders,
if any. The holders of common stock have no preemptive or
conversion rights and are not subject to further calls or
assessments. There are no redemption or sinking fund provisions
applicable to the common stock. The rights of the holders of the
common stock are subject to any rights that may be fixed for
holders of preferred stock, if any. All of the outstanding shares
of common stock are fully paid and non-assessable. Our common stock
is listed on the Nasdaq Capital Market under the symbol “HEPA.”
Anti-Takeover Effects of Certain Provisions of Hepion
Certificate of Incorporation, Bylaws and the DGCL
Certain provisions of our certificate of incorporation and bylaws,
which are summarized in the following paragraphs, may have the
effect of discouraging potential acquisition proposals or making a
tender offer or delaying or preventing a change in control,
including changes a stockholder might consider favorable. Such
provisions may also prevent or frustrate attempts by our
stockholders to replace or remove our management. In particular,
our certificate of incorporation and bylaws and Delaware law, as
applicable, among other things:
• provide the Board of Directors with the ability to alter the
bylaws without stockholder approval; and
• provide that vacancies on
the Board of Directors may be filled by a majority of directors in
office, although less than a quorum.
These provisions are expected to discourage certain types of
coercive takeover practices and inadequate takeover bids and to
encourage persons seeking to acquire control of Hepion to first
negotiate with its board. These provisions may delay or prevent
someone from acquiring or merging with Hepion, which may cause the
market price of Hepion common stock to decline.
Blank
Check Preferred. Our Board of
Directors is authorized to create and issue from time to time,
without stockholder approval, up to an aggregate of 20,000,000
shares of preferred stock in one or more series and to establish
the number of shares of any series of preferred stock and to fix
the designations, powers, preferences and rights of the shares of
each series and any qualifications, limitations or restrictions of
the shares of each series.
The authority to
designate preferred stock may be used to issue series of preferred
stock, or rights to acquire preferred stock, that could dilute the
interest of, or impair the voting power of, holders of the common
stock or could also be used as a method of determining, delaying or
preventing a change of control.
Advance
Notice Bylaws. The Bylaws contain
an advance notice procedure for stockholder proposals to be brought
before any meeting of stockholders, including proposed nominations
of persons for election to our Board of Directors. Stockholders at
any meeting will only be able to consider proposals or nominations
specified in the notice of meeting or brought before the meeting by
or at the direction of our Board of Directors or by a stockholder
who was a stockholder of record on the record date for the meeting,
who is entitled to vote at the meeting and who has given Hepion's
corporate secretary timely written notice, in proper form, of the
stockholder's intention to bring that business before the meeting.
Although the Bylaws do not give our Board of Directors the power to
approve or disapprove stockholder nominations of candidates or
proposals regarding other business to be conducted at a special or
annual meeting, the Bylaws may have the effect of precluding the
conduct of certain business at a meeting if the proper procedures
are not followed or may discourage or deter a potential acquirer
from conducting a solicitation of proxies to elect its own slate of
directors or otherwise attempting to obtain control of us.
UNDERWRITING
We have entered into an underwriting agreement, dated
,
2020, with ThinkEquity, a division of Fordham Financial Management,
Inc., acting as the sole book-running manager (sometimes referred
to as the “representative”). Subject to the terms and conditions of
the underwriting agreement, we have agreed to sell to each
underwriter named below, and each underwriter named below has
severally agreed to purchase, at the public offering price less the
underwriting discounts set forth on the cover page of this
prospectus, the number of shares of common stock listed next to its
name in the following table:
Underwriters |
|
Number of
Shares |
ThinkEquity, a division
of Fordham Financial Management, Inc. |
|
|
|
Total |
|
|
|
The underwriting agreement provides that the obligations of the
underwriters to pay for and accept delivery of the shares of common
stock offered by this prospectus are subject to various conditions
and representations and warranties, including the approval of
certain legal matters by their counsel and other conditions
specified in the underwriting agreement. The shares of common stock
are offered by the underwriters, subject to prior sale, when, as
and if issued to and accepted by them. The underwriters reserve the
right to withdraw, cancel or modify the offer to the public and to
reject orders in whole or in part. The underwriters are obligated
to take and pay for all of the shares of common stock offered by
this prospectus if any such shares of common stock are taken, other
than those shares of common stock covered by the
over-allotment option described below.
We have agreed to indemnify the underwriters and certain of their
affiliates and controlling persons (within the meaning of Section
15 of the Securities Act or Section 20 of the Exchange Act), among
others, against specified liabilities, including liabilities under
the Securities Act, and to contribute to payments the underwriters
may be required to make in respect thereof.
Discounts, Commissions and Reimbursement
The underwriters propose to offer the shares of common stock
directly to the public at the public offering price set forth on
the cover page of this prospectus. After the offering to the
public, the offering price and other selling terms may be changed
by the underwriters without changing the proceeds we will receive
from the underwriters.
The following table summarizes the public offering price,
underwriting discounts and commissions and proceeds before expenses
to us. The underwriting commissions are 7.0% of the public offering
price. The information assumes either no exercise or full exercise
of the over-allotment option we granted to the representative of
the underwriters.
|
|
Per
Share |
|
|
Total
Without
Over-allotment
Option |
|
|
Total
With
Over-allotment
Option |
Public
offering price |
|
$ |
|
|
|
$ |
|
|
|
$ |
|
Underwriting
discounts and commissions (7.0%) |
|
$ |
|
|
|
$ |
|
|
|
$ |
|
Proceeds, before expenses, to us |
|
$ |
|
|
|
$ |
|
|
|
$ |
|
We have paid an expense deposit of $25,000 to the representative,
which will be applied against out-of-pocket accountable expenses
that will be paid by us to the underwriters in connection with this
offering, and will be reimbursed to us to the extent not actually
incurred in compliance with FINRA Rule 5110(g)(4)(A).
We have also agreed to pay certain of the representative’s expenses
relating to the offering, including (a) all filing fees and
communication expenses relating to the registration of the shares
of common stock to be sold in the offering (including the share’s
subject to the underwriters’ over-allotment option) with the
Commission; (b) all public filing system filing fees associated
with the review of the offering by FINRA; (c) all fees and expenses
relating to the listing of such shares of common stock on The
Nasdaq Capital Market and such other stock exchanges as we and the
representative together determine; (d) all fees, expenses and
disbursements relating to background checks of our officers and
directors in an amount not to exceed $15,000 in the aggregate; (e)
all fees, expenses and disbursements relating to the registration
or qualification of the common stock under the “blue sky”
securities laws of such states and other jurisdictions as the
representative may reasonably designate; (f) all fees, expenses and
disbursements relating to the registration, qualification or
exemption of the common stock under the securities laws of such
foreign jurisdictions as the representative may reasonably
designate; (g) the costs of all mailing and printing of the
underwriting documents (including, without limitation, the
underwriting agreement, any blue sky surveys and, if appropriate,
any agreement among underwriters, selected dealers’ agreement,
underwriters’ questionnaire and power of attorney), registration
statements, prospectuses and all amendments, supplements and
exhibits thereto and as many preliminary and final prospectuses as
the representative may reasonably deem necessary; (h) the costs and
expenses of a public relations firm; (i) the costs of preparing,
printing and delivering certificates representing the common stock;
(j) fees and expenses of the transfer agent for the shares of
common stock; (k) stock transfer and/or stamp taxes, if any,
payable upon the transfer of securities from us to the
underwriters; (l) the costs associated with post-closing
advertising the offering in the national editions of the Wall
Street Journal and New York Times; (m) the costs associated with
bound volumes of the public offering materials as well as
commemorative mementos and lucite tombstones, each of which us or
our designee shall provide within a reasonable time after the
closing date in such quantities as the representative may
reasonably request, in an amount not to exceed $3,000; (n) the fees
and expenses of our accountants; (o) the fees and expenses of our
legal counsel and other agents and representatives; (p) fees and
expenses of the representative’s legal counsel not to exceed
$100,000; and (q) the $29,500 cost associated with the
underwriters’ use of Ipreo’s book-building, prospectus tracking and
compliance software for the offering.
Our total estimated expenses of the offering, including
registration, filing and listing fees, printing fees and legal and
accounting expenses, but excluding underwriting discounts and
commissions, are approximately
$ .
Over-allotment Option
We have granted a 45-day option to the representative of the
underwriters to purchase up
to additional
shares of common stock (equal to 15% of the common stock sold in
this offering) from us solely to cover over-allotments, if any, at
the public offering price less underwriting discounts and
commissions.
Representative’s Warrants
Upon closing of this offering, we have agreed to issue to the
representative as compensation warrants to purchase a number of
shares of common stock equal to 3% of the aggregate number of
shares of common stock sold in this offering, or the
Representative’s Warrants. The Representative’s Warrants will be
exercisable at a per share exercise price equal to 125% of the
public offering price per share in this offering. The
Representative’s Warrants are exercisable at any time and from time
to time, in whole or in part, during the four and one half year
period commencing 180 days from the effective date of the
registration statement of which this prospectus is a part.
The Representative’s Warrants have been deemed compensation by
FINRA and are therefore subject to a 180-day lock-up pursuant to
Rule 5110(e)(1) of FINRA. The representative (or permitted
assignees under Rule 5110(e)(2)) will not sell, transfer, assign,
pledge, or hypothecate these warrants or the securities underlying
these warrants, nor will they engage in any hedging, short sale,
derivative, put, or call transaction that would result in the
effective economic disposition of the warrants or the underlying
securities for a period of 180 days from the effective date of the
registration statement. In addition, the warrants provide for
registration rights upon request, in certain cases. The one-time
demand registration right provided will not be greater than five
years from the effective date of the registration statement in
compliance with FINRA Rule 5110(g)(8)(A). The unlimited piggyback
registration right provided will not be greater than seven years
from the effective date of the registration statement in compliance
with FINRA Rule 5110(g)(8)(D). We will bear all fees and expenses
attendant to registering the securities issuable on exercise of the
warrants other than underwriting commissions incurred and payable
by the holders. The exercise price and number of shares issuable
upon exercise of the warrants may be adjusted in certain
circumstances including in the event of a stock dividend or our
recapitalization, reorganization, merger or consolidation. However,
the warrant exercise price or underlying shares will not be
adjusted for issuances of shares of common stock at a price below
the warrant exercise price.
Right of First Refusal
Until , 2021 (six
(6) months from the closing date), the representative will have an
irrevocable right of first refusal to act as sole investment
banker, sole book-runner and/or sole placement agent, at its sole
discretion, for each and every of our future public equity and debt
offerings, including all equity linked financings, for us, or any
of our successors or subsidiaries, on terms customary to the
representative. The representative in conjunction with us, has the
sole right to determine whether or not any other broker-dealer
shall have the right to participate in any such offering and the
economic terms of any such participation.
Lock-Up Agreements
Pursuant to “lock-up” agreements, we, our executive officers and
directors, have agreed, without the prior written consent of the
representative, not to, directly or indirectly, offer pledge, sell,
contract to sell, grant, lend or otherwise transfer or dispose of
any of shares of (or enter into any transaction or device that is
designed to, or could be expected to, result in the transfer or
disposition by any person at any time in the future of) our common
stock, enter into any swap or other derivatives transaction that
transfers to another, in whole or in part, any of the economic
benefits or risks of ownership of shares of our common stock, make
any demand for or exercise any right or cause to be filed a
registration statement, including any amendments thereto, with
respect to the registration of any shares of common stock or
securities convertible into or exercisable or exchangeable for
common stock or any other securities of ours or publicly disclose
the intention to do any of the foregoing, subject to customary
exceptions, for a period of (i) six months after the date of this
prospectus in the case of directors and officers and (ii) three
months after the date of this prospectus in the case of the
Company.
Determination of Offering Price
The public offering price of the securities we are offering was
negotiated between us and the underwriters based on the trading of
our common stock prior to the offering, among other things. Other
factors considered in determining the public offering price of the
shares include the history and prospects of the Company, the stage
of development of our business, our business plans for the future
and the extent to which they have been implemented, an assessment
of our management, general conditions of the securities markets at
the time of the offering and such other factors as were deemed
relevant.
Other Relationships
Certain of the underwriters and their affiliates have, from time to
time, provided and may in the future provide, various investment
banking and other financial services for us for which they may
receive customary fees. In particular, ThinkEquity provided
advisory services to us from July 2019 through February 2020 for
which we paid ThinkEquity $17,000. In the course of their
businesses, the underwriters and their affiliates may actively
trade our securities or loans for their own account or for the
accounts of customers, and, accordingly, the underwriters and their
affiliates may at any time hold long or short positions in such
securities or loans.
In 2020, we engaged B. Riley FBR, Inc. (“B. Riley”) to act as a
placement agent. In connection with such engagement, we granted B.
Riley a right for a tail fee equal to 7% of the gross proceeds
raised by us from certain investors in connection with certain
financing transactions consummated by us within a three-month
period ending November 17, 2020.
Listing
Our common stock is listed on The Nasdaq Capital Market under the
symbol “HEPA”.
Price Stabilization, Short Positions and Penalty Bids
In connection with this offering, the underwriters may engage in
transactions that stabilize, maintain or otherwise affect the price
of our common stock. The underwriters may elect to stabilize the
price of our common stock by bidding for, and purchasing, common
stock in the open market.
The underwriters may also impose a penalty bid. This occurs when a
particular underwriter or dealer repays selling concessions allowed
to it for distributing a security in this offering because the
underwriter repurchases that security in stabilizing or short
covering transactions.
Finally, the underwriters may bid for, and purchase, shares of our
common stock in market making transactions, including “passive”
market making transactions as described below.
These activities may stabilize or maintain the market price of our
common stock at a price that is higher than the price that might
otherwise exist in the absence of these activities. The
underwriters are not required to engage in these activities, and
may discontinue any of these activities at any time without notice.
These transactions may be effected on the Nasdaq Capital Market, in
the over-the-counter market, or otherwise.
In connection with this offering, the underwriters or their
affiliates may engage in passive market making transactions in our
common stock immediately prior to the commencement of sales in this
offering, in accordance with Rule 103 of Regulation M under the
Exchange Act. Rule 103 generally provides that:
|
● |
a passive market maker may not effect transactions or display bids
for our common stock in excess of the highest independent bid price
by persons who are not passive market makers;
|
|
● |
net purchases by a passive market maker on each day are generally
limited to 30% of the passive market maker’s average daily trading
volume in our common stock during a specified two-month prior
period or 200 shares of common stock, whichever is greater, and
must be discontinued when that limit is reached; and
|
|
● |
passive
market making bids must be identified as such. |
Electronic Distribution
This prospectus in electronic format may be made available on
websites or through other online services maintained by one or more
of the underwriters, or by their affiliates. Other than this
prospectus in electronic format, the information on any
underwriter’s website and any information contained in any other
website maintained by an underwriter is not part of this prospectus
or the registration statement of which this prospectus forms a
part, has not been approved and/or endorsed by us or any
underwriter in its capacity as underwriter, and should not be
relied upon by investors.
Offer Restrictions Outside The United States
Other than in the United States, no action has been taken by us or
the underwriters that would permit a public offering of the
securities offered by this prospectus in any jurisdiction where
action for that purpose is required. The securities offered by this
prospectus may not be offered or sold, directly or indirectly, nor
may this prospectus or any other offering material or
advertisements in connection with the offer and sale of any such
securities be distributed or published in any jurisdiction, except
under circumstances that will result in compliance with the
applicable rules and regulations of that jurisdiction. Persons into
whose possession this prospectus comes are advised to inform
themselves about and to observe any restrictions relating to this
offering and the distribution of this prospectus. This prospectus
does not constitute an offer to sell or a solicitation of an offer
to buy any securities offered by this prospectus in any
jurisdiction in which such an offer or a solicitation is
unlawful.
Australia
This prospectus is not a disclosure document under Chapter 6D of
the Australian Corporations Act, has not been lodged with the
Australian Securities and Investments Commission and does not
purport to include the information required of a disclosure
document under Chapter 6D of the Australian Corporations Act.
Accordingly, (i) the offer of the securities under this prospectus
is only made to persons to whom it is lawful to offer the
securities without disclosure under Chapter 6D of the Australian
Corporations Act under one or more exemptions set out in section
708 of the Australian Corporations Act, (ii) this prospectus is
made available in Australia only to those persons as set forth in
clause (i) above, and (iii) the offeree must be sent a notice
stating in substance that by accepting this offer, the offeree
represents that the offeree is such a person as set forth in clause
(i) above, and, unless permitted under the Australian Corporations
Act, agrees not to sell or offer for sale within Australia any of
the securities sold to the offeree within 12 months after its
transfer to the offeree under this prospectus.
China
The information in this document does not constitute a public offer
of the securities, whether by way of sale or subscription, in the
People’s Republic of China (excluding, for purposes of this
paragraph, Hong Kong Special Administrative Region, Macau Special
Administrative Region and Taiwan). The securities may not be
offered or sold directly or indirectly in the PRC to legal or
natural persons other than directly to “qualified domestic
institutional investors.”
European Economic Area — Belgium, Germany, Luxembourg and
Netherlands
The information in this document has been prepared on the basis
that all offers of securities will be made pursuant to an exemption
under the Directive 2003/71/EC, or the Prospectus Directive, as
implemented in Member States of the European Economic Area, or a
Relevant Member State, from the requirement to produce a prospectus
for offers of securities.
An offer to the public of securities has not been made, and may not
be made, in a Relevant Member State except pursuant to one of the
following exemptions under the Prospectus Directive as implemented
in that Relevant Member State:
• to legal entities that are authorized or
regulated to operate in the financial markets or, if not so
authorized or regulated, whose corporate purpose is solely to
invest in securities;
• to any legal entity that has two or more
of (i) an average of at least 250 employees during its last fiscal
year; (ii) a total balance sheet of more than €43,000,000 (as shown
on its last annual unconsolidated or consolidated financial
statements) and (iii) an annual net turnover of more than
€50,000,000 (as shown on its last annual unconsolidated or
consolidated financial statements);
• to fewer than 100 natural or legal
persons (other than qualified investors within the meaning of
Article 2(1)(e) of the Prospectus Directive) subject to obtaining
the prior consent of our company or any underwriter for any such
offer; or
• in any other circumstances falling within
Article 3(2) of the Prospectus Directive, provided that no such
offer of securities shall result in a requirement for the
publication by us of a prospectus pursuant to Article 3 of the
Prospectus Directive.
France
This document is not being distributed in the context of a public
offering of financial securities (offre au public de titres
financiers) in France within the meaning of Article L.411-1 of the
French Monetary and Financial Code (Code monétaire et financier)
and Articles 211-1 et seq. of the General Regulation of the French
Autorité des marchés financiers, or AMF. The securities have not
been offered or sold and will not be offered or sold, directly or
indirectly, to the public in France.
This document and any other offering material relating to the
securities have not been, and will not be, submitted to the AMF for
approval in France and, accordingly, may not be distributed or
caused to distributed, directly or indirectly, to the public in
France.
Such offers, sales and distributions have been and shall only be
made in France to (i) qualified investors (investisseurs qualifiés)
acting for their own account, as defined in and in accordance with
Articles L.411-2-II-2° and D.411-1 to D.411-3, D. 744-1, D.754-1
and D.764-1 of the French Monetary and Financial Code and any
implementing regulation and/or (ii) a restricted number of
non-qualified investors (cercle restreint d’investisseurs) acting
for their own account, as defined in and in accordance with
Articles L.411-2-II-2° and D.411-4, D.744-1, D.754-1 and D.764-1 of
the French Monetary and Financial Code and any implementing
regulation.
Pursuant to Article 211-3 of the General Regulation of the AMF,
investors in France are informed that the securities cannot be
distributed (directly or indirectly) to the public by the investors
otherwise than in accordance with Articles L.411-1, L.411-2,
L.412-1 and L.621-8 to L.621-8-3 of the French Monetary and
Financial Code.
Ireland
The information in this document does not constitute a prospectus
under any Irish laws or regulations and this document has not been
filed with or approved by any Irish regulatory authority as the
information has not been prepared in the context of a public
offering of securities in Ireland within the meaning of the Irish
Prospectus (Directive 2003/71/EC) Regulations 2005, or the
Prospectus Regulations. The securities have not been offered or
sold, and will not be offered, sold or delivered directly or
indirectly in Ireland by way of a public offering, except to (i)
qualified investors as defined in Regulation 2(l) of the Prospectus
Regulations and (ii) fewer than 100 natural or legal persons who
are not qualified investors.
Israel
The securities offered by this prospectus have not been approved or
disapproved by the Israeli Securities Authority, or the ISA, nor
have such securities been registered for sale in Israel. The shares
may not be offered or sold, directly or indirectly, to the public
in Israel, absent the publication of a prospectus. The ISA has not
issued permits, approvals or licenses in connection with this
offering or publishing the prospectus; nor has it authenticated the
details included herein, confirmed their reliability or
completeness, or rendered an opinion as to the quality of the
securities being offered. Any resale in Israel, directly or
indirectly, to the public of the securities offered by this
prospectus is subject to restrictions on transferability and must
be effected only in compliance with the Israeli securities laws and
regulations.
Italy
The offering of the securities in the Republic of Italy has not
been authorized by the Italian Securities and Exchange Commission
(Commissione Nazionale per le Societ-$$-Aga e la Borsa), or CONSOB,
pursuant to the Italian securities legislation and, accordingly, no
offering material relating to the securities may be distributed in
Italy and such securities may not be offered or sold in Italy in a
public offer within the meaning of Article 1.1(t) of Legislative
Decree No. 58 of 24 February 1998, or Decree No. 58, other
than:
•
to Italian qualified investors, or
Qualified Investors, as defined in Article 100 of Decree no.58 by
reference to Article 34-ter of CONSOB Regulation no. 11971 of 14
May 1999, or Regulation no. 1197l, as amended; and
• in other circumstances that are exempt
from the rules on public offer pursuant to Article 100 of Decree
No. 58 and Article 34-ter of Regulation No. 11971 as amended.
Any offer, sale or delivery of the securities or distribution of
any offer document relating to the securities in Italy (excluding
placements where a Qualified Investor solicits an offer from the
issuer) under the paragraphs above must be:
• made by investment firms, banks or
financial intermediaries permitted to conduct such activities in
Italy in accordance with Legislative Decree No. 385 of 1 September
1993 (as amended), Decree No.58, CONSOB Regulation No. 16190 of 29
October 2007 and any other applicable laws; and
• in compliance with all relevant Italian
securities, tax and exchange controls and any other applicable
laws.
Any subsequent distribution of the securities in Italy must be made
in compliance with the public offer and prospectus requirement
rules provided under Decree No. 58 and the Regulation No. 11971 as
amended, unless an exception from those rules applies. Failure to
comply with such rules may result in the sale of such securities
being declared null and void and in the liability of the entity
transferring the securities for any damages suffered by the
investors.
Japan
The securities have not been and will not be registered under
Article 4, paragraph 1 of the Financial Instruments and Exchange
Law of Japan (Law No. 25 of 1948), as amended, or the FIEL,
pursuant to an exemption from the registration requirements
applicable to a private placement of securities to Qualified
Institutional Investors (as defined in and in accordance with
Article2, paragraph 3 of the FIEL and the regulations promulgated
thereunder). Accordingly, the securities may not be offered or
sold, directly or indirectly, in Japan or to, or for the benefit
of, any resident of Japan other than Qualified Institutional
Investors. Any Qualified Institutional Investor who acquires
securities may not resell them to any person in Japan that is not a
Qualified Institutional Investor, and acquisition by any such
person of securities is conditional upon the execution of an
agreement to that effect.
Portugal
This document is not being distributed in the context of a public
offer of financial securities (oferta pública de valores
mobiliários) in Portugal, within the meaning of Article 109 of the
Portuguese Securities Code (Código dos Valores Mobiliários). The
securities have not been offered or sold and will not be offered or
sold, directly or indirectly, to the public in Portugal. This
document and any other offering material relating to the securities
have not been, and will not be, submitted to the Portuguese
Securities Market Commission (Comissăo do Mercado de Valores
Mobiliários) for approval in Portugal and, accordingly, may not be
distributed or caused to distributed, directly or indirectly, to
the public in Portugal, other than under circumstances that are
deemed not to qualify as a public offer under the Portuguese
Securities Code. Such offers, sales and distributions of securities
in Portugal are limited to persons who are “qualified investors”
(as defined in the Portuguese Securities Code). Only such investors
may receive this document and they may not distribute it or the
information contained in it to any other person.
Sweden
This document has not been, and will not be, registered with or
approved by Finansinspektionen (the Swedish Financial Supervisory
Authority). Accordingly, this document may not be made available,
nor may the securities be offered for sale in Sweden, other than
under circumstances that are deemed not to require a prospectus
under the Swedish Financial Instruments Trading Act (1991:980) (Sw.
lag (1991:980) om handel med finansiella instrument). Any offering
of securities in Sweden is limited to persons who are “qualified
investors” (as defined in the Financial Instruments Trading Act).
Only such investors may receive this document and they may not
distribute it or the information contained in it to any other
person.
Switzerland
The securities may not be publicly offered in Switzerland and will
not be listed on the SIX Swiss Exchange, or SIX, or on any other
stock exchange or regulated trading facility in Switzerland. This
document has been prepared without regard to the disclosure
standards for issuance prospectuses under art. 652a or art. 1156 of
the Swiss Code of Obligations or the disclosure standards for
listing prospectuses under art. 27 ff. of the SIX Listing Rules or
the listing rules of any other stock exchange or regulated trading
facility in Switzerland. Neither this document nor any other
offering material relating to the securities may be publicly
distributed or otherwise made publicly available in
Switzerland.
Neither this document nor any other offering material relating to
the securities have been or will be filed with or approved by any
Swiss regulatory authority. In particular, this document will not
be filed with, and the offer of securities will not be supervised
by, the Swiss Financial Market Supervisory Authority.
This document is personal to the recipient only and not for general
circulation in Switzerland.
United Arab Emirates
Neither this document nor the securities have been approved,
disapproved or passed on in any way by the Central Bank of the
United Arab Emirates or any other governmental authority in the
United Arab Emirates, nor have we received authorization or
licensing from the Central Bank of the United Arab Emirates or any
other governmental authority in the United Arab Emirates to market
or sell the securities within the United Arab Emirates. This
document does not constitute and may not be used for the purpose of
an offer or invitation. No services relating to the securities,
including the receipt of applications and/or the allotment or
redemption of such shares, may be rendered within the United Arab
Emirates by us.
No offer or invitation to subscribe for securities is valid or
permitted in the Dubai International Financial Centre.
United Kingdom
Neither the information in this document nor any other document
relating to the offer has been delivered for approval to the
Financial Services Authority in the United Kingdom and no
prospectus (within the meaning of section 85 of the Financial
Services and Markets Act 2000, as amended, or FSMA) has been
published or is intended to be published in respect of the
securities. This document is issued on a confidential basis to
“qualified investors” (within the meaning of section 86(7) of FSMA)
in the United Kingdom, and the securities may not be offered or
sold in the United Kingdom by means of this document, any
accompanying letter or any other document, except in circumstances
which do not require the publication of a prospectus pursuant to
section 86(1) FSMA. This document should not be distributed,
published or reproduced, in whole or in part, nor may its contents
be disclosed by recipients to any other person in the United
Kingdom.
Any invitation or inducement to engage in investment activity
(within the meaning of section 21 of FSMA) received in connection
with the issue or sale of the securities has only been communicated
or caused to be communicated and will only be communicated or
caused to be communicated in the United Kingdom in circumstances in
which section 21(1) of FSMA does not apply to us.
In the United Kingdom, this document is being distributed only to,
and is directed at, persons (i) who have professional experience in
matters relating to investments falling within Article 19(5)
(investment professionals) of the Financial Services and Markets
Act 2000 (Financial Promotions) Order 2005, or FPO, (ii) who fall
within the categories of persons referred to in Article 49(2)(a) to
(d) (high net worth companies, unincorporated associations, etc.)
of the FPO or (iii) to whom it may otherwise be lawfully
communicated (together “relevant persons”). The investments to
which this document relates are available only to, and any
invitation, offer or agreement to purchase will be engaged in only
with, relevant persons. Any person who is not a relevant person
should not act or rely on this document or any of its contents.
Canada
The securities may be sold in Canada only to purchasers purchasing,
or deemed to be purchasing, as principal that are accredited
investors, as defined in National Instrument 45-106 Prospectus
Exemptions or subsection 73.3(1) of the Securities Act (Ontario),
and are permitted clients, as defined in National Instrument 31-103
Registration Requirements, Exemptions and Ongoing Registrant
Obligations. Any resale of the securities must be made in
accordance with an exemption from, or in a transaction not subject
to, the prospectus requirements of applicable securities laws.
Securities legislation in certain provinces or territories of
Canada may provide a purchaser with remedies for rescission or
damages if this prospectus (including any amendment thereto)
contains a misrepresentation, provided that the remedies for
rescission or damages are exercised by the purchaser within the
time limit prescribed by the securities legislation of the
purchaser’s province or territory. The purchaser should refer to
any applicable provisions of the securities legislation of the
purchaser’s province or territory for particulars of these rights
or consult with a legal advisor. Pursuant to section 3A.3 of
National Instrument 33-105 Underwriting Conflicts (NI 33-105), the
underwriters are not required to comply with the disclosure
requirements of NI33-105 regarding underwriter conflicts of
interest in connection with this offering.
LEGAL MATTERS
The validity of the shares of our common stock offered hereby will
be passed upon for us by Sheppard, Mullin, Richter &
Hampton LLP, New York, New York. Blank Rome LLP, New York, New
York has acted as counsel for the underwriters in connection with
certain legal matters related to this offering.
EXPERTS
The consolidated financial statements as of December 31, 2019
and December 31, 2018 and for the years ended
December 31, 2019 and 2018, incorporated by reference in this
prospectus and in the registration statement have been so
incorporated in reliance on the report of BDO USA, LLP, an
independent registered public accounting firm, incorporated by
reference herein, given on the authority of said firm as experts in
auditing and accounting. The report on the consolidated financial
statements contains an explanatory paragraph regarding the
Company’s ability to continue as a going concern.
WHERE YOU CAN FIND MORE
INFORMATION
This prospectus, which constitutes a part of the registration
statement on Form S-1 that we have filed with the SEC under
the Securities Act, does not contain all of the information in the
registration statement and its exhibits. For further information
with respect to us and the common stock offered by this prospectus,
you should refer to the registration statement and the exhibits
filed as part of that document. Statements contained in this
prospectus as to the contents of any contract or any other document
referred to are not necessarily complete, and in each instance, we
refer you to the copy of the contract or other document filed as an
exhibit to the registration statement. Each of these statements is
qualified in all respects by this reference.
We are subject to the reporting requirements of the Exchange Act
and file annual, quarterly and current reports, proxy statements
and other information with the SEC. You can read our SEC filings,
including the registration statement, over the Internet at the
SEC’s website at http://www.sec.gov. We also maintain a
website at http://www.hepionpharma.com, at which you may
access these materials free of charge as soon as reasonably
practicable after they are electronically filed with, or furnished
to, the SEC. The information contained in, or that can be accessed
through, our website is not part of this prospectus.
INCORPORATION OF CERTAIN DOCUMENTS
BY REFERENCE
The SEC allows us to “incorporate by reference” information that we
file with them. Incorporation by reference allows us to disclose
important information to you by referring you to those other
documents. The information incorporated by reference is an
important part of this prospectus, and information that we file
later with the SEC will automatically update and supersede this
information. We filed a registration statement on Form S-1
under the Securities Act with the SEC with respect to the
securities being offered pursuant to this prospectus. This
prospectus omits certain information contained in the registration
statement, as permitted by the SEC. You should refer to the
registration statement, including the exhibits, for further
information about us and the securities being offered pursuant to
this prospectus. Statements in this prospectus regarding the
provisions of certain documents filed with, or incorporated by
reference in, the registration statement are not necessarily
complete and each statement is qualified in all respects by that
reference. Copies of all or any part of the registration statement,
including the documents incorporated by reference or the exhibits,
may be obtained upon payment of the prescribed rates at the offices
of the SEC listed above in “Where You Can Find More Information”.
We are incorporating by reference the documents listed below, which
we have already filed with the SEC.
1. The
Company’s Annual Report on Form 10-K for the year ended
December 31, 2019, filed with the SEC on May 14, 2020;
2. Amendment
Number 1 to the Company’s Annual Report on Form 10-K for the
year ended December 31, 2019, filed with the SEC on June 15,
2020;
3. The Company Quarterly
Reports on Form 10-Q for (i) the quarter ended March 31,
2020, filed with the SEC on June 29, 2020 and (ii) the
quarter ended June 30, 2020, filed with the SEC on August 12, 2020;
4. The Company’s Definitive Proxy
Statement filed with the SEC on June 12, 2020;
5. The Company’s Current
Reports on Form 8-K filed with the SEC on January 6, 2020, January 9, 2020, January 28, 2020, February 12, 2020 (two reports), February 20, 2020, March 12, 2020, March 27, 2020, March 30, 2020, April 17, 2020, May 14, 2020, May 19, 2020, May 20, 2020, June 10, 2020, June 22, 2020, June 29, 2020, July 7, 2020, July 30, 2020, August 5, 2020, August 12, 2020, August 27, 2020, September 1, 2020, September 17, 2020, September 29, 2020, October 5, 2020 and October 27, 2020; and
6. The
description of the Company’s common stock contained in the
registration statement on Form 8-A filed with the SEC on
February 24, 2015 pursuant to Section 12 of the Exchange
Act of 1934, as amended (the “Exchange Act”), including any
amendment or report filed for the purpose of updating that
description.
We also incorporate by reference all documents (other than Current
Reports furnished under Item 2.02 or Item 7.01 of
Form 8-K and exhibits filed on such form that are related to
such items) that are subsequently filed by us with the Securities
and Exchange Commission pursuant to Sections 13(a), 13(c), 14
or 15(d) of the Exchange Act prior to the termination of the
offering of the securities made by this prospectus (including
documents filed after the date of the initial Registration
Statement of which this prospectus is a part and prior to the
effectiveness of the Registration Statement). These documents
include periodic reports, such as Annual Reports on Form 10-K,
Quarterly Reports on Form 10-Q and Current Reports on
Form 8-K, as well as proxy statements.
Any statement contained in this prospectus or in a document
incorporated or deemed to be incorporated by reference into this
prospectus will be deemed to be modified or superseded to the
extent that a statement contained in this prospectus or any
subsequently filed document that is deemed to be incorporated by
reference into this prospectus modifies or supersedes the
statement
You may request, and we will provide you with, a copy of these
filings, at no cost, by calling us at (732) 902-4000 or
by writing to us at the following address:
Hepion Pharmaceuticals, Inc.
399 Thornall Street, First Floor
Edison, New Jersey, 08837
Attn.: Secretary
Shares of Common
Stock
Hepion Pharmaceuticals, Inc.
ThinkEquity |
a division of Fordham
Financial Management, Inc. |
,
2020
PART II
INFORMATION NOT REQUIRED IN PROSPECTUS
Item 13. Other Expenses of Issuance and
Distribution
The following table provides information regarding the various
actual and anticipated expenses (other than underwriting fees and
expenses) payable by us in connection with the issuance and
distribution of the securities being registered hereby. All amounts
shown are estimates except the SEC registration fee.
Item |
|
Amount |
|
SEC registration fee |
|
$ |
3,764 |
|
FINRA
filing fee |
|
|
* |
|
Printing and engraving expenses |
|
|
* |
|
Legal
fees and expenses |
|
|
* |
|
Accounting fees and expenses |
|
|
* |
|
Transfer agents’ fees and expenses |
|
|
* |
|
Miscellaneous costs |
|
|
* |
|
Total |
|
|
* |
|
* |
To be
provided by amendment |
Item 14. Indemnification of Directors and
Officers
The DGCL authorizes corporations to limit or eliminate the personal
liability of directors to corporations and their stockholders for
monetary damages for breaches of directors’ fiduciary duties as
directors and our amended and restated certificate of incorporation
includes such an exculpation provision. Our certificate of
incorporation and by-laws include provisions that indemnify, to the
fullest extent allowable under the DGCL, the personal liability of
directors or officers for monetary damages for actions taken as a
director or officer of us, or for serving at our request as a
director or officer or another position at another corporation or
enterprise, as the case may be. Our certificate of incorporation
and by-laws also provide that we must indemnify and advance
reasonable expenses to our directors and officers, subject to our
receipt of an undertaking from the indemnified party as may be
required under the DGCL. Our certificate of incorporation expressly
authorizes us to carry directors’ and officers’ insurance to
protect us, our directors, officers and certain employees for some
liabilities. The limitation of liability and indemnification
provisions in our amended and restated certificate of incorporation
and by-laws may discourage stockholders from bringing a lawsuit
against directors for breach of their fiduciary duty. These
provisions may also have the effect of reducing the likelihood of
derivative litigation against our directors and officers, even
though such an action, if successful, might otherwise benefit us
and our stockholders. However, these provisions do not limit or
eliminate our rights, or those of any stockholder, to seek
non-monetary relief such as injunction or rescission in the event
of a breach of a director’s duty of care. The provisions do not
alter the liability of directors under the federal securities laws.
In addition, your investment may be adversely affected to the
extent that, in a class action or direct suit, we pay the costs of
settlement and damage awards against directors and officers
pursuant to these indemnification provisions. There is currently no
pending material litigation or proceeding against any of our
directors, officers or employees for which indemnification is
sought.
Item 15. Recent Sales of Unregistered
Securities
The Company has sold the securities described below within the past
three years which were not registered under the Securities Act. All
of the sales listed below were made pursuant to an exemption from
registration afforded by Section 4(a)(2) of the Securities Act
and Regulation D thereunder.
On March 13, 2019, the Company entered into a securities
purchase agreement (the “Securities Purchase Agreement”) with an
accredited investor. Pursuant to the Securities Purchase Agreement,
the Company issued to the investor in a private placement
(i) 47,429 shares of Company common stock and (ii) an
unsecured $1.25 million aggregate principal amount
debenture.
On May 8, 2018, the Company entered into a securities purchase
agreement with Iliad Research and Trading, L.P. (“IRT”), pursuant
to which the Company issued to IRT a secured convertible promissory
note in the aggregate principal amount of $3,325,000 for an
aggregate purchase price of $2,000,000 cash and $1,000,000
aggregate principal amount of investor notes payable to the Company
in four tranches of $250,000 upon request by the Company. Closing
occurred on May 9, 2018.
Item 16. Exhibits and Financial Statement
Schedules
|
(a) |
Exhibits. See Exhibit Index set forth on page II-4
to this Registration Statement. |
|
(b) |
Financial Statements. Incorporated by reference into
this registration statement. |
Item 17. Undertakings.
(a) The undersigned registrant hereby undertakes as follows:
(1) To file, during any period in which offers or sales are being
made, a post-effective amendment to this registration
statement:
(i) To include any prospectus required by Section 10(a)(3) of the
Securities Act of 1933;
(ii) To reflect in the prospectus any facts or events arising after
the effective date of the registration statement (or the most
recent post-effective amendment thereof) which, individually or in
the aggregate, represent a fundamental change in the information
set forth in the registration statement. Notwithstanding the
foregoing, any increase or decrease in volume of securities offered
(if the total dollar value of securities offered would not exceed
that which was registered) and any deviation from the low or high
end of the estimated maximum offering range may be reflected in the
form of prospectus filed with the Commission pursuant to Rule
424(b) if, in the aggregate, the changes in volume and price
represent no more than 20 percent change in the maximum aggregate
offering price set forth in the "Calculation of Registration Fee"
table in the effective registration statement; and
(iii) To include any material information with respect to the plan
of distribution not previously disclosed in the registration
statement or any material change to such information in the
registration statement.
provided, however, that
paragraphs (a)(1)(i), (a)(1)(ii) and (a)(1)(iii) do not apply
if the information required to be included in a post-effective
amendment by those paragraphs is contained in reports filed with or
furnished to the Commission by the registrant pursuant to
Section 13 or Section 15(d) of the Exchange Act that are
incorporated by reference in the Registration Statement
(2) That, for the purpose of determining any liability under the
Securities Act of 1933, each such post-effective amendment shall be
deemed to be a new registration statement relating to the
securities offered therein, and the offering of such securities at
that time shall be deemed to be the initial bona fide offering
thereof.
(3) To remove from registration by means of a post-effective
amendment any of the securities being registered which remain
unsold at the termination of the offering.
(4) That, for the purpose of determining any liability under the
Securities Act of 1933 to any purchaser in the initial distribution
of the securities, the undersigned registrant undertakes that in a
primary offering of securities of the undersigned registrant
pursuant to this registration statement, regardless of the
underwriting method used to sell the securities to the purchaser,
if the securities are offered or sold to such purchaser by means of
any of the following communications, the undersigned registrant
will be a seller to the purchaser and will be considered to offer
or sell such securities to such purchaser:
(i) Any preliminary prospectus or prospectus of the undersigned
registrant relating to the offering required to be filed pursuant
to Rule 424;
(ii) Any free writing prospectus relating to the offering prepared
by or on behalf of the undersigned registrant or used or referred
to by the undersigned registrant;
(iii) The portion of any other free writing prospectus relating to
the offering containing material information about the undersigned
registrant or our securities provided by or on behalf of the
undersigned registrant; and
(iv) Any other communication that is an offer in the offering made
by the undersigned registrant to the purchaser.
(b) The undersigned registrant hereby
undertakes that, for purposes of determining any liability under
the Securities Act, each filing of the registrant's annual report
pursuant to Section 13(a) or Section 15(d) of the
Exchange Act (and, where applicable, each filing of an employee
benefit plan's annual report pursuant to Section 15(d) of the
Exchange Act) that is incorporated by reference in the registration
statement shall be deemed to be a new registration statement
relating to the securities offered therein, and the offering of
such securities at that time shall be deemed to be the initial bona
fide offering thereof.
(c) Insofar as indemnification for liabilities arising under the
Securities Act of 1933 may be permitted to directors, officers and
controlling persons of the undersigned pursuant to the foregoing
provisions, or otherwise, the undersigned has been advised that in
the opinion of the SEC such indemnification is against public
policy as expressed in the Securities Act and is, therefore,
unenforceable. In the event that a claim for indemnification
against such liabilities (other than the payment by the undersigned
of expenses incurred or paid by a director, officer or controlling
person of the undersigned in the successful defense of any action,
suit or proceeding) is asserted by such director, officer or
controlling person in connection with the securities being
registered, the undersigned will, unless in the opinion of our
counsel the matter has been settled by controlling precedent,
submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in
the Act and will be governed by the final adjudication of such
issue.
(d) The undersigned tegistrant hereby undertakes
that:
(1) for purposes of determining any liability
under the Securities Act, the information omitted from the form of
prospectus filed as part of this Registration Statement in reliance
upon Rule 430A and contained in a form of prospectus filed by
the registrant pursuant to Rule 424(b)(1) or (4) or
497(h) under the Securities Act shall be deemed to be part of this
Registration Statement as of the time it was declared
effective.
(2) for the purpose of determining any liability
under the Securities Act, each post-effective amendment that
contains a form of prospectus shall be deemed to be a new
registration statement relating to the securities offered therein,
and the offering of such securities at that time shall be deemed to
be the initial bona fide offering thereof.
EXHIBIT INDEX
Exhibit
Number |
|
Exhibit Description |
1.1** |
|
Form of Underwriting
Agreement. |
3.1(a) |
|
Certificate of
Incorporation of the Company (filed as Exhibit 3.1 to the
Company’s registration statement on Form 10-12G filed with the
Securities and Exchange Commission on August 8, 2013 and
incorporated herein by reference). |
3.1(b) |
|
Certificate of
Designation, Preferences and Rights of the Series A
Convertible Preferred Stock of the Company filed with the Secretary
of State of the State of Delaware on October 14, 2014 (filed
as Exhibit 3.1 to the Company’s Current Report on
Form 8-K filed with the Securities and Exchange Commission on
October 15, 2014 and incorporated herein by
reference). |
3.1(c) |
|
Certificate of
Designation, Preferences and Rights of the Series B
Convertible Preferred Stock of the Company filed with the Secretary
of State of the State of Delaware on December 18, 2014 (filed
as Exhibit 3.1 to the Company’s Current Report on
Form 8-K filed with the Securities and Exchange Commission on
December 18, 2014 and incorporated herein by
reference). |
3.1(d) |
|
Certificate of
Designation of Preferences, Rights and Limitations of Series C
Convertible Preferred Stock filed with the Secretary of State of
the State of Delaware on July 2, 2018 (filed as
Exhibit 3.1 to the Company’s Current Report on Form 8-K
filed with the Securities and Exchange Commission on July 5,
2018 and incorporated herein by reference). |
3.1(e) |
|
Certificate of
Designation of Preferences, Rights and Limitations of Series D
Convertible Preferred Stock filed with the Secretary of State of
the State of Delaware on April 26, 2019 (filed as
Exhibit 3.1 to the Company’s Current Report on Form 8-K
filed with the Securities and Exchange Commission on May 8,
2019 and incorporated herein by reference). |
3.1(f) |
|
Certificate of Amendment of
Certificate of Incorporation of Company dated May 25, 2018 (filed
as Exhibit 3.1 to the Company’s Current Report on Form 8-K
filed with the Securities and Exchange Commission on May 29, 2018
and incorporated herein by reference); |
3.1(g) |
|
Certificate of
Designation of Preference, Rights and Limitations of Series E
Convertible Preferred Stock, filed with the Secretary of State of
the State of Delaware on June 18, 2019 (filed as Exhibit 3.1 to the
Company’s Current Report on Form 8-K filed with the Securities and
Exchange Commission on June 20, 2019 and incorporated herein by
reference). |
3.1(h) |
|
Certificate of Amendment
to the Certificate of Incorporation, filed with the Secretary of
State of the State of Delaware on dated May 28, 2019 (incorporated
by reference filed as Exhibit 3.1 to the Company’s Current Report
on Form 8-K filed with the Securities and Exchange Commission on
May 31, 2019 and incorporated herein by reference) |
3.1(i) |
|
Certificate of Amendment
to the Certificate of Incorporation, dated July 18, 2019 (filed as
Exhibit 3.1 to the Company’s Current Report on Form 8-K filed with
the Securities and Exchange Commission on July 23, 2019 and
incorporated herein by reference). |
3.2 |
|
By Laws of the Company
(filed as Exhibit 3.2 to the Company’s registration statement
on Form 10-12G filed with the Securities and Exchange
Commission on August 8, 2013 and incorporated herein by
reference). |
4.1 |
|
Warrant Agency
Agreement, dated as of July 2, 2018, by and between the
Company and Philadelphia Stock Transfer, Inc. (filed as
Exhibit 4.1 to the Company’s Current Report on Form 8-K
filed with the Securities and Exchange Commission on July 5,
2018 and incorporated herein by reference). |
4.2 |
|
Form of Warrant issued
in April 2019 Offering (filed as Exhibit 4.1 to Form S-1 filed with
the Securities and Exchange Commission on April 18, 2019 and
incorporated herein by reference). |
4.3 |
|
Form of Warrant issued in June 2019
Offering (filed as Exhibit 4.1 to Form S-1 filed with the
Securities and Exchange Commission on June 5, 2019 and incorporated
herein by reference). |
4.4 |
|
Form of Warrant to be issued to the
Investors (filed as Exhibit 4.1 to the Company’s Current Report on
Form 8-K filed with the Securities and Exchange Commission on March
30, 2016 and incorporated herein by reference). |
4.5 |
|
Form of Warrant to be issued to the
Investors (filed as Exhibit 4.1 to the Company’s Current Report on
Form 8-K filed with the Securities and Exchange Commission on April
25, 2017 and incorporated herein by reference). |
4.6** |
|
Form of Representative’s Warrant |
Exhibit
Number |
|
Exhibit Description |
5.1** |
|
Opinion of
Sheppard, Mullin, Richter & Hampton LLP. |
10.1 |
|
Executive Agreement,
dated April 1, 2016, between the Company and John Cavan (filed
as Exhibit 10.1 to the Company’s Current Report on
Form 8-K filed with the Securities and Exchange Commission on
March 31, 2016 and incorporated herein by
reference). |
10.2 |
|
2013 Equity Incentive
Plan (filed as Exhibit 10.1 to the Company’s Form S-8
filed with the Securities and Exchange Commission on May 4,
2015 and incorporated herein by reference). |
10.3 |
|
Executive Agreement, dated
June 1, 2016, between the Company and Dr. Robert T.
Foster (filed as Exhibit 10.1 to the Company’s Current Report
on Form 8-K filed with the Securities and Exchange Commission
on June 13, 2016 and incorporated herein by
reference). |
10.4* |
|
Promissory Note dated April 13,
2020. |
10.5* |
|
Agreement and Plan of Merger by and among
the Company, Ciclofilin Acquisition Corp., Ciclofilin
Pharmaceuticals, Inc. and Robert Foster, Pharm.D., PH.D., as
Stockholder Representative, dated as of May 26, 2016. |
10.6 |
|
Amendment to 2013 Equity Incentive
Plan (filed as Appendix A to the Company's Definitive Proxy
Statement filed with the Securities and Exchange Commission on June
12, 2020 and incorporated herein by reference). |
21.1 |
|
List of Subsidiaries. (filed as
Exhibit 21.1 to the Company’s Form 10-K filed with the
Securities and Exchange Commission on May 14, 2020 and
incorporated herein by reference). |
23.1* |
|
Consent of BDO
USA, LLP, Independent Registered Public Accounting
Firm. |
23.2** |
|
Consent of Sheppard,
Mullin, Richter & Hampton, LLP (included as part of
Exhibit 5.1). |
24* |
|
Power of Attorney
(included on signature page hereto). |
|
** |
To be filed by amendment. |
SIGNATURES
Pursuant to the requirements of the Securities Act of 1933, as
amended, the Registrant certifies that it has reasonable grounds to
believe that it meets all of the requirements for filing on
Form S-1 and has duly caused this registration statement on
Form S-1 to be signed on its behalf by the undersigned,
thereunto duly authorized, in Edison, New Jersey, on the 29th day
of October 2020.
|
HEPION PHARMACEUTICALS, INC. |
|
|
|
|
By: |
/s/ Robert Foster |
|
|
Robert Foster |
|
|
President, Chief Executive Officer and
Director |
POWER OF ATTORNEY
KNOW
ALL MEN BY THESE PRESENTS, that each person whose signature appears
below constitutes and appoints Robert Foster and John Cavan, his
true and lawful attorneys-in-fact and agent with full power of
substitution and re-substitution, for him and in his name, place
and stead, in any and all capacities to sign any or all amendments
(including, without limitation, post-effective amendments) to this
Registration Statement, any related Registration Statement filed
pursuant to Rule 462(b) under the Securities Act of 1933 and
any or all pre- or post-effective amendments thereto, and to file
the same, with all exhibits thereto, and all other documents in
connection therewith, with the Securities and Exchange Commission,
granting unto said attorneys-in-fact and agent, full power and
authority to do and perform each and every act and thing requisite
and necessary to be done in and about the premises, as fully for
all intents and purposes as he might or could do in person, hereby
ratifying and confirming that said attorneys-in-fact and agent, or
any substitute or substitutes for him, may lawfully do or cause to
be done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, the
following persons in the capacities and on the dates indicated have
signed this Registration Statement below.
Signature |
|
Title |
Date |
|
|
|
|
/s/ Robert Foster |
|
President,
Chief Executive Officer and Director |
|
Robert
Foster |
|
(Principal Executive
Officer) |
October
29, 2020 |
|
|
|
|
/s/ John Cavan |
|
Chief
Financial Officer (Principal Financial and |
|
John
Cavan |
|
Accounting Officer) |
October
29, 2020 |
|
|
|
|
/s/ Gary S. Jacob |
|
Chairman
of the Board |
|
Gary
S. Jacob |
|
|
October
29, 2020 |
|
|
|
|
/s/ Timothy Block |
|
Director |
|
Timothy Block |
|
|
October
29, 2020 |
|
|
|
|
/s/ Thomas H. Adams |
|
Director |
|
Thomas
H. Adams |
|
|
October
29, 2020 |
|
|
|
|
/s/ John Brancaccio |
|
Director |
|
John
Brancaccio |
|
|
October
29, 2020 |
|
|
|
|
/s/ Arnold Lippa |
|
Director |
|
Arnold
Lippa |
|
|
October
29, 2020 |
|
|
|
|
/s/ Petrus Wijngaard |
|
Director |
|
Petrus
Wijngaard |
|
|
October
29, 2020 |
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