
Bicara Therapeutics is a clinical-stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Our lead program ficerafusp alfa is a bifunctional antibody that combines two clinically validated targets, an epidermal growth factor receptor... Bicara Therapeutics is a clinical-stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Our lead program ficerafusp alfa is a bifunctional antibody that combines two clinically validated targets, an epidermal growth factor receptor, or EGFR, directed monoclonal antibody with a domain that binds to human transforming growth factor beta, or TGF-b. Ficerafusp alfa is initially being developed in head and neck squamous cell carcinoma, or HNSCC, where there remains a significant unmet need. We intend to initiate a pivotal Phase 2/3 trial of ficerafusp alfa in combination with pembrolizumab as a first-line therapy in recurrent/metastatic HNSCC excluding HPV-positive patients with oropharyngeal squamous cell carcinoma late in the fourth quarter of 2024 or early in the first quarter of 2025. Show more
Period | Change | Change % | Open | High | Low | Avg. Daily Vol | VWAP | |
---|---|---|---|---|---|---|---|---|
1 | -1.87 | -16.1345987921 | 11.59 | 12.74 | 9.63 | 511104 | 11.39942057 | CS |
4 | -5.59 | -36.5120836055 | 15.31 | 15.7702 | 7.8 | 1433989 | 10.70705658 | CS |
12 | -4.14 | -29.8701298701 | 13.86 | 16.22 | 7.8 | 847662 | 11.78188985 | CS |
26 | -7.48 | -43.488372093 | 17.2 | 19.75 | 7.8 | 669484 | 12.80375986 | CS |
52 | -16.53 | -62.9714285714 | 26.25 | 27.95 | 7.8 | 568359 | 14.9360731 | CS |
156 | -16.53 | -62.9714285714 | 26.25 | 27.95 | 7.8 | 568359 | 14.9360731 | CS |
260 | -16.53 | -62.9714285714 | 26.25 | 27.95 | 7.8 | 568359 | 14.9360731 | CS |
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