Cardiovascular Systems to Webcast Fiscal Third-Quarter Earnings Conference Call Wednesday, May 6

Cardiovascular Systems, Inc. (CSI) (Nasdaq: CSII) will host a live webcast of its fiscal third-quarter conference call on Wednesday, May 6, 2009, at 4 p.m. CT (5 p.m. ET). David L. Martin, president and chief executive officer of CSI, and Laurence L. Betterley, chief financial officer, will discuss the company�s results for the fiscal third quarter ended March 31, 2009 and outlook for the remainder of the fiscal year.

To access the live webcast, go to the investor information section of the company�s Web site, www.csi360.com, on the day of the conference call and click on the webcast icon. A webcast replay will be available beginning at 7 p.m. CT the same day.

To participate in the conference call, dial (888) 713-4214 and enter 26726197. Please dial in at least 10 minutes prior to the call. Participants may pre-register online for the call by logging on to the following Web site: https://www.theconferencingservice.com/prereg/key.process?key=PVLJH9LB3

If you do not have access to the Internet and want to listen to an audio replay of the conference call, dial 888-286-8010 and enter access number 71489482. The audio replay will be available beginning at 8 p.m. CT on Wednesday, May 6, 2009, through 6 p.m. CT on Friday, May 8, 2009.

Cardiovascular Systems, Inc. is a medical device company focused on developing and commercializing interventional treatment systems for vascular disease. The company�s Diamondback 360�TM Orbital Atherectomy System is capable of treating a broad range of plaque types both above and below the knee, including calcified vessel lesions, and addresses many of the limitations associated with existing treatment alternatives. In August 2007, the U.S. FDA granted 510(k) clearance for the use of the Diamondback 360� as a therapy for PAD (peripheral arterial disease). Since then, the Diamondback 360� has been adopted by more than 400 hospitals across the United States. Cardiovascular Systems is a public company with shares traded on the NASDAQ Global Market� under the symbol �CSII.� For more information visit the company�s Web site at www.csi360.com.

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