crudeoil24
2 years ago
Sierra Oncology Gets Loan to Support Myelofibrosis Drug Potential Rollout Following Positive Results
7:34 am ET January 25, 2022 (Dow Jones) Print
By Kimberly Chin
Sierra Oncology Inc. said it has secured a term loan with Oxford Finance LLC that will mostly support the commercial preparation and potential rollout of momelotinib, an investigational drug that treats myelofibrosis, following positive results from an advanced trial.
The biopharmaceutical company on Tuesday said that a Phase 3 trial for momelotinib in patients with the rare form of blood cancer met all of its primary and secondary key endpoints. The company saw a statistically significant benefit in the reduction of symptoms, blood transfusions due to anemia and splenic size.
The patients were symptomatic, anemic and had previously been treated with an approved JAK inhibitor, the company said.
Sierra plans to submit a new drug application with the U.S. Food and Drug Administration in the second quarter.
The company has drawn an initial $5 million term loan at the closing of its financing agreement with Oxford. It will be able to access up to an additional $120 million in several tranches, $70 million of which will be determined by reaching certain milestones, such as regulatory approval in the U.S. About $50 million will be at the lender's discretion, it said.
The company could receive proceeds of $33.3 million if it exercises all of its Series B warrants, which expire in 75 days, Sierra said.
stocksrising
3 years ago
Yes, starter position @ $13βs..certain read outs next Qtr , but more importantly perhaps this: Chief Executive Officer Stephen Dilly, MBBS, PhD, will present an overview of the company at the LifeSci Partners Precision Oncology Day taking place Wednesday, February 17, 2021.
StocktonCA
5 years ago
any ideas why it shot up 30% today with 8 mil vol??? i follow the Baker Bros, and bought this at .37 after seeing it was #94 in their new stock list. i had bought LEAP, which was #93 in their recent new stocks list at .80 and sold it at 1.04, the very next day it shot up over70% I could not believe it if I would have just held for one more day! Oh well I still made a little profit however I been invested in best stock which I think will do the same 1 year I turn $5,000 into $75,000 by buying one of the stocks on their board which they still hold acad. if you go to www.j3sg.com and under institutions type in Baker bros advisory llc you can see their portfolio. when i first started following them their portfolio was worth 4 billion. now it is worth 14 billion.
Value_Investor
5 years ago
Are you sure the forthcoming Huge R/S will be 1:100? When will that happen? What are the condition and price to exercise the Entire 445M shares of Warrants (A, B, and Gilead)? Are all 333M Newly-diluted common shares be converted at $0.33 per share?
Anyway if the OS is 850M shares then most likely 1:100 R/S will kick in very soon!
Hopefully SRRA will hold strong support at $0.272 tomorrow, instead of retest its Bottom $0.2 ~ $0.2156 so that $0.4312 could be hit as soon as the coming week...
$0.40 and $0.48 will be the two Very Strong resistances besides $0.35, $0.36, $0.38, and $0.44 etc. Strong resistances.