FORM 4
☐ Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

ALVAREZ EDUARDO		 2. Issuer Name and Ticker or Trading Symbol

AMYRIS, INC. [ AMRS ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
CHIEF OPERATING OFFICER
(Last)          (First)          (Middle)

C/O AMYRIS, INC., 5885 HOLLIS STREET, SUITE 100		 3. Date of Earliest Transaction (MM/DD/YYYY)

4/4/2023
(Street)

EMERYVILLE, CA 94608		 4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
 6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)        (State)        (Zip)
Rule 10b5-1(c) Transaction Indication
☐ Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 4/4/2023  M  492000 (1)A (2)843914 D  
Common Stock 4/5/2023  S  231368 (3)D$1.2288 (4)612546 D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)		2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)		8. Price of Derivative Security
(Instr. 5)		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Performance-based Restricted Stock Units  (2)4/4/2023  M     492000 (1)  (5) (5)Common Stock 492000.0  (2)0 D  
Explanation of Responses:
(1) Represents performance-based restricted stock units ("PSUs") that vested upon achievement of certain pre-established performance metrics as approved by the Issuer's Leadership, Development, Inclusion, and Compensation Committee of the Board of Directors (the "COO PSU Achievement") in connection with the PSUs awarded to the Reporting Person on May 24, 2021.
(2) Each PSU represents a contingent right to receive one share of Issuer's common stock. This transaction represents the settlement of PSUs in shares of common stock on their scheduled vesting date.
(3) Shares sold to satisfy the Reporting Person's tax withholding obligation upon vesting of PSUs in connection with the COO PSU Achievement.
(4) The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.22 to $1.2289, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth herein.
(5) This PSU award was granted on May 24, 2021. After the end of the performance period (December 31, 2022), the Issuer's Leadership, Development, Inclusion, and Compensation Committee of the Board of Directors determined that 492,000 PSUs had vested of the original 600,000 PSUs awarded, based on the achievement of certain pre-established performance metrics.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
ALVAREZ EDUARDO
C/O AMYRIS, INC.
5885 HOLLIS STREET, SUITE 100
EMERYVILLE, CA 94608

CHIEF OPERATING OFFICER
Signatures
/s/ Eduardo Alvarez by Doris Choi, Attorney-in-Fact4/6/2023
**Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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