UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

FORM N-Q

QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF
REGISTERED MANAGEMENT INVESTMENT COMPANY

Investment Company Act file number: 811-7852

Exact Name of Registrant as Specified in Charter: USAA MUTUAL FUNDS TRUST

Address of Principal Executive Offices and Zip Code: 9800 FREDERICKSBURG ROAD

SAN ANTONIO, TX 78288

Name and Address of Agent for Service: CHRISTOPHER P. LAIA
 USAA MUTUAL FUNDS TRUST
 9800 FREDERICKSBURG ROAD
 SAN ANTONIO, TX 78288

Registrant's Telephone Number, Including Area Code: (210) 498-0226

Date of Fiscal Year End: DECEMBER 31

Date of Reporting Period: SEPTEMBER 30, 2009

ITEM 1. SCHEDULE OF INVESTMENTS.
USAA MUTUAL FUNDS TRUST - 3RD QUARTER REPORT - PERIOD ENDED SEPTEMBER 30, 2009

USAA S&P 500 INDEX FUND, REWARD SHARES
USAA S&P 500 INDEX FUND, MEMBER SHARES

[LOGO OF USAA]
USAA(R)

PORTFOLIO OF INVESTMENTS
3RD QUARTER

USAA S&P 500 INDEX FUND
September 30, 2009

(Form N-Q)

48414-1109 (c)2009, USAA. All rights reserved.



PORTFOLIO OF INVESTMENTS 1
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)

NUMBER
OF SHARES SECURITY MARKET VALUE (000)
----------- -------- ------------------

 COMMON STOCKS (99.0%)

 CONSUMER DISCRETIONARY (9.0%)
 -----------------------------
 ADVERTISING (0.2%)
 125,600 Interpublic Group of Companies, Inc. * $ 945
 85,600 Omnicom Group, Inc. 3,162
 ------------------
 4,107
 ------------------

 APPAREL & ACCESSORIES & LUXURY GOODS (0.2%)
 89,900 Coach, Inc. 2,959
 16,700 Polo Ralph Lauren Corp. 1,280
 25,358 VF Corp. 1,837
 ------------------
 6,076
 ------------------

 APPAREL RETAIL (0.4%)
 25,900 Abercrombie & Fitch Co. "A" 852
 132,578 Gap, Inc. 2,837
 76,800 Limited Brands, Inc. 1,305
 116,858 TJX Companies, Inc. 4,341
 ------------------
 9,335
 ------------------

 AUTO PARTS & EQUIPMENT (0.2%)
 164,600 Johnson Controls, Inc. 4,207
 ------------------

 AUTOMOBILE MANUFACTURERS (0.2%)
 885,941 Ford Motor Co. * 6,388
 ------------------

 AUTOMOTIVE RETAIL (0.1%)
 24,711 AutoNation, Inc. * 447
 8,977 AutoZone, Inc. * 1,312
 37,100 O'Reilly Automotive, Inc. * 1,341
 ------------------
 3,100
 ------------------

 BROADCASTING (0.1%)
 192,274 CBS Corp. "B" 2,317
 ------------------

 CABLE & SATELLITE (0.8%)
 793,699 Comcast Corp. "A" 13,406
 125,581 DIRECTV Group, Inc. * 3,463
 22,600 Scripps Networks Interactive "A" 835
 96,871 Time Warner Cable, Inc. 4,174
 ------------------
 21,878
 ------------------

 CASINOS & GAMING (0.1%)
 82,696 International Game Technology 1,777
 19,979 Wynn Resorts Ltd. (g)* (1,416)
 ------------------
 3,193
 ------------------

 COMPUTER & ELECTRONICS RETAIL (0.2%)
 93,250 Best Buy Co., Inc. 3,499
 44,000 GameStop Corp. "A" * 1,165
 37,500 RadioShack Corp. 621
 ------------------
 5,285
 ------------------

 CONSUMER ELECTRONICS (0.0%)
 20,965 Harman International Industries, Inc. 710
 ------------------

 DEPARTMENT STORES (0.4%)
 62,900 J.C. Penney Co., Inc. 2,123
 85,935 Kohl's Corp. * 4,903
 119,502 Macy's, Inc. 2,186
 45,300 Nordstrom, Inc. 1,383
 13,018 Sears Holdings Corp. (g)* (850)
 ------------------
 11,445
 ------------------

 DISTRIBUTORS (0.1%)

PORTFOLIO OF INVESTMENTS (continued) 2
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)


NUMBER
OF SHARES SECURITY MARKET VALUE (000)
----------- -------- ------------------

 43,400 Genuine Parts Co. 1,652
 ------------------




 EDUCATION SERVICES (0.1%)
 35,781 Apollo Group, Inc. "A" * 2,636
 16,900 DeVry, Inc. 935
 ------------------
 3,571
 ------------------

 FOOTWEAR (0.3%)
 108,700 NIKE, Inc. "B" 7,033
 ------------------

 GENERAL MERCHANDISE STORES (0.4%)
 23,800 Big Lots, Inc. * 596
 38,000 Family Dollar Stores, Inc. 1,003
 210,095 Target Corp. 9,807
 ------------------
 11,406
 ------------------

 HOME FURNISHINGS (0.0%)
 44,300 Leggett & Platt, Inc. 859
 ------------------

 HOME IMPROVEMENT RETAIL (0.9%)
 473,737 Home Depot, Inc. 12,620
 412,400 Lowe's Companies, Inc. 8,636
 26,500 Sherwin-Williams Co. 1,594
 ------------------
 22,850
 ------------------

 HOMEBUILDING (0.1%)
 75,700 D.R. Horton, Inc. 864
 21,900 KB Home 364
 39,900 Lennar Corp. "A" 568
 84,637 Pulte Homes, Inc. 930
 ------------------
 2,726
 ------------------

 HOMEFURNISHING RETAIL (0.1%)
 73,500 Bed Bath & Beyond, Inc. * 2,759
 ------------------

 HOTELS, RESORTS & CRUISE LINES (0.3%)
 122,900 Carnival Corp. 4,090
 70,695 Marriott International, Inc. "A" 1,951
 50,800 Starwood Hotels & Resorts Worldwide, Inc. 1,678
 47,262 Wyndham Worldwide Corp. 771
 ------------------
 8,490
 ------------------

 HOUSEHOLD APPLIANCES (0.1%)
 16,300 Black & Decker Corp. 754
 20,193 Whirlpool Corp. 1,413
 ------------------
 2,167
 ------------------

 HOUSEWARES & SPECIALTIES (0.1%)
 43,430 Fortune Brands, Inc. 1,866
 73,100 Newell Rubbermaid, Inc. 1,147
 ------------------
 3,013
 ------------------

 INTERNET RETAIL (0.4%)
 92,343 Amazon.com, Inc. * 8,621
 56,053 Expedia, Inc. * 1,343
 ------------------
 9,964
 ------------------

 LEISURE PRODUCTS (0.1%)
 33,800 Hasbro, Inc. 938
 99,300 Mattel, Inc. 1,833
 ------------------
 2,771
 ------------------

 MOTORCYCLE MANUFACTURERS (0.1%)
 64,900 Harley-Davidson, Inc. 1,493
 ------------------

 MOVIES & ENTERTAINMENT (1.4%)
 625,373 News Corp. "A" 7,498
 328,800 Time Warner, Inc. 9,463
 171,000 Viacom, Inc. "B" * 4,795
 516,608 Walt Disney Co. 14,186
 ------------------
 35,942
 ------------------

 PHOTOGRAPHIC PRODUCTS (0.0%)
 75,400 Eastman Kodak Co. (g) (360)
 ------------------

PORTFOLIO OF INVESTMENTS (continued) 3
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)


NUMBER
OF SHARES SECURITY MARKET VALUE (000)
----------- -------- ------------------

 PUBLISHING (0.2%)
 61,200 Gannett Co., Inc. 766
 88,000 McGraw-Hill Companies, Inc. 2,212
 10,000 Meredith Corp. 299
 35,200 New York Times Co. "A" 286
 1,811 Washington Post Co. "B" 848
 ------------------
 4,411
 ------------------

 RESTAURANTS (1.0%)
 40,375 Darden Restaurants, Inc. 1,378
 302,119 McDonald's Corp. 17,242
 207,400 Starbucks Corp. * 4,283
 128,100 Yum! Brands, Inc. 4,324
 ------------------
 27,227
 ------------------

 SPECIALIZED CONSUMER SERVICES (0.1%)
 90,300 H&R Block, Inc. 1,660
 ------------------

 SPECIALTY STORES (0.3%)
 71,700 Office Depot, Inc. * 475
 202,733 Staples, Inc. 4,707
 33,600 Tiffany & Co. 1,295
 ------------------
 6,477
 ------------------

 TIRES & RUBBER (0.0%)
 64,800 Goodyear Tire & Rubber Co. * 1,103
 ------------------
 Total Consumer Discretionary 235,975
 ------------------

 CONSUMER STAPLES (11.4%)
 ------------------------
 AGRICULTURAL PRODUCTS (0.2%)
 179,979 Archer-Daniels-Midland Co. 5,259
 ------------------

 BREWERS (0.1%)
 42,300 Molson Coors Brewing Co. "B" 2,059
 ------------------

 DISTILLERS & VINTNERS (0.1%)
 31,206 Brown-Forman Corp. "B" 1,505
 56,500 Constellation Brands, Inc. "A" * 856
 ------------------
 2,361
 ------------------

 DRUG RETAIL (0.9%)
 401,085 CVS Caremark Corp. 14,335
 276,834 Walgreen Co. 10,373
 ------------------
 24,708
 ------------------

 FOOD DISTRIBUTORS (0.2%)
 165,800 Sysco Corp. 4,120
 ------------------

 FOOD RETAIL (0.3%)
 179,900 Kroger Co. 3,713
 113,428 Safeway, Inc. 2,237
 55,425 SUPERVALU, Inc. 835
 38,700 Whole Foods Market, Inc. * 1,180
 ------------------
 7,965
 ------------------

 HOUSEHOLD PRODUCTS (2.5%)
 39,900 Clorox Co. 2,347
 137,714 Colgate-Palmolive Co. 10,505
 116,409 Kimberly-Clark Corp. 6,866
 810,681 Procter & Gamble Co. 46,954
 ------------------
 66,672
 ------------------

 HYPERMARKETS & SUPER CENTERS (1.4%)
 120,100 Costco Wholesale Corp. 6,781
 600,902 Wal-Mart Stores, Inc. (f) (29,498)
 ------------------
 36,279
 ------------------

 PACKAGED FOODS & MEAT (1.4%)
 51,707 Campbell Soup Co. 1,687
 120,646 ConAgra Foods, Inc. 2,616
 48,600 Dean Foods Co. * 865
 90,310 General Mills, Inc. 5,814
 88,600 H.J. Heinz Co. 3,522
 44,800 Hershey Co. 1,741
 19,200 Hormel Foods Corp. 682

PORTFOLIO OF INVESTMENTS (continued) 4
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)


NUMBER
OF SHARES SECURITY MARKET VALUE (000)
----------- -------- ------------------


 33,926 J.M. Smucker Co. 1,798
 71,285 Kellogg Co. 3,509
 406,949 Kraft Foods, Inc. "A" 10,691
 37,717 McCormick & Co., Inc. 1,280
 196,900 Sara Lee Corp. 2,193
 79,200 Tyson Foods, Inc. "A" 1,000
 ------------------
 37,398
 ------------------

 PERSONAL PRODUCTS (0.2%)
 119,600 Avon Products, Inc. 4,062
 31,300 Estee Lauder Companies, Inc. "A" 1,160
 ------------------
 5,222
 ------------------

 SOFT DRINKS (2.5%)
 643,311 Coca-Cola Co. 34,546
 91,225 Coca-Cola Enterprises, Inc. 1,953
 68,900 Dr Pepper Snapple Group, Inc. * 1,981
 40,319 Pepsi Bottling Group, Inc. 1,469
 432,900 PepsiCo, Inc. 25,394
 ------------------
 65,343
 ------------------

 TOBACCO (1.6%)
 575,800 Altria Group, Inc. 10,255
 46,225 Lorillard, Inc. 3,434
 538,118 Philip Morris International, Inc. 26,228
 45,600 Reynolds American, Inc. 2,030
 ------------------
 41,947
 ------------------
 ------------------
 Total Consumer Staples 299,333
 ------------------

 ENERGY (11.6%)
 --------------
 COAL & CONSUMABLE FUELS (0.2%)
 50,300 CONSOL Energy, Inc. 2,269
 25,300 Massey Energy Co. 706
 74,700 Peabody Energy Corp. 2,780
 ------------------
 5,755
 ------------------

 INTEGRATED OIL & GAS (6.9%)
 556,269 Chevron Corp. 39,178
 412,014 ConocoPhillips 18,607
 1,333,756 Exxon Mobil Corp. (f) (91,509)
 80,423 Hess Corp. 4,299
 197,740 Marathon Oil Corp. 6,308
 53,728 Murphy Oil Corp. 3,093
 225,295 Occidental Petroleum Corp. 17,663
 ------------------
 180,657
 ------------------

 OIL & GAS DRILLING (0.2%)
 19,100 Diamond Offshore Drilling, Inc. 1,824
 38,600 ENSCO International, Inc. 1,642
 81,700 Nabors Industries Ltd. * 1,708
 33,700 Rowan Companies, Inc. 777
 ------------------
 5,951
 ------------------

 OIL & GAS EQUIPMENT & SERVICES (1.7%)
 85,000 Baker Hughes, Inc. 3,626
 85,000 BJ Services Co. 1,652
 59,700 Cameron International Corp. * 2,258
 34,500 FMC Technologies, Inc. * 1,802
 252,021 Halliburton Co. 6,835
 115,300 National Oilwell Varco, Inc. * 4,973
 332,503 Schlumberger Ltd. 19,817
 60,400 Smith International, Inc. 1,733
 ------------------
 42,696
 ------------------

 OIL & GAS EXPLORATION & PRODUCTION (2.1%)
 135,600 Anadarko Petroleum Corp. 8,506
 92,800 Apache Corp. 8,522
 30,724 Cabot Oil & Gas Corp. 1,098
 177,576 Chesapeake Energy Corp. 5,043
 68,300 Denbury Resources, Inc. * 1,033
 123,500 Devon Energy Corp. 8,315
 70,200 EOG Resources, Inc. 5,863
 46,961 Noble Energy, Inc. 3,098
 34,200 Pioneer Natural Resources Co. 1,241
 43,244 Range Resources Corp. 2,135

PORTFOLIO OF INVESTMENTS (continued) 5
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)


NUMBER
OF SHARES SECURITY MARKET VALUE (000)
----------- -------- ------------------

 96,700 Southwestern Energy Co. * 4,127
 162,407 XTO Energy, Inc. 6,711
 ------------------
 55,692
 ------------------

 OIL & GAS REFINING & MARKETING (0.2%)
 34,400 Sunoco, Inc. 979
 41,000 Tesoro Corp. 614
 156,873 Valero Energy Corp. 3,042
 ------------------
 4,635
 ------------------

 OIL & GAS STORAGE & TRANSPORTATION (0.3%)
 186,900 El Paso Corp. 1,929
 182,250 Spectra Energy Corp. 3,452
 163,714 Williams Companies, Inc. 2,925
 ------------------
 8,306
 ------------------
 ------------------
 Total Energy 303,692
 ------------------

 FINANCIALS (15.1%)
 ------------------
 ASSET MANAGEMENT & CUSTODY BANKS (1.4%)
 70,060 Ameriprise Financial, Inc. 2,545
 332,549 Bank of New York Mellon Corp., Inc. 9,641
 22,400 Federated Investors, Inc. "B" 591
 40,802 Franklin Resources, Inc. 4,105
 117,478 Invesco Ltd. 2,674
 50,388 Janus Capital Group, Inc. 714
 46,221 Legg Mason, Inc. 1,434
 65,600 Northern Trust Corp. (c) (3,815)
 138,642 State Street Corp. 7,293
 72,700 T. Rowe Price Group, Inc. 3,322
 ------------------
 36,134
 ------------------

 CONSUMER FINANCE (0.7%)
 331,185 American Express Co. 11,227
 127,058 Capital One Financial Corp. 4,540
 149,955 Discover Financial Services 2,434
 133,300 SLM Corp. * 1,162
 ------------------
 19,363
 ------------------

 DIVERSIFIED BANKS (1.9%)
 43,300 Comerica, Inc. 1,285
 532,534 U.S. Bancorp 11,641
 1,298,140 Wells Fargo & Co. 36,581
 ------------------
 49,507
 ------------------

 INSURANCE BROKERS (0.3%)
 76,100 Aon Corp. 3,097
 143,200 Marsh & McLennan Companies, Inc. 3,541
 ------------------
 6,638
 ------------------

 INVESTMENT BANKING & BROKERAGE (1.7%)
 263,547 Charles Schwab Corp. 5,047
 225,363 E*TRADE Financial Corp. * 394
 141,639 Goldman Sachs Group, Inc. 26,111
 377,775 Morgan Stanley 11,666
 ------------------
 43,218
 ------------------

 LIFE & HEALTH INSURANCE (1.1%)
 131,100 AFLAC, Inc. 5,603
 83,811 Lincoln National Corp. 2,172
 226,700 MetLife, Inc. 8,630
 90,165 Principal Financial Group, Inc. 2,470
 127,800 Prudential Financial, Inc. 6,378
 23,600 Torchmark Corp. 1,025
 90,400 Unum Group 1,938
 ------------------
 28,216
 ------------------

 MULTI-LINE INSURANCE (0.4%)
 37,832 American International Group, Inc. (g)* (1,669)
 35,117 Assurant, Inc. 1,126
 127,800 Genworth Financial, Inc. "A" 1,527
 106,300 Hartford Financial Services Group, Inc. 2,817
 101,116 Loews Corp. 3,463
 ------------------
 10,602
 ------------------

 MULTI-SECTOR HOLDINGS (0.0%)

PORTFOLIO OF INVESTMENTS (continued) 6
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)


NUMBER
OF SHARES SECURITY MARKET VALUE (000)
----------- -------- ------------------

 50,400 Leucadia National Corp. * 1,246
 ------------------

 OTHER DIVERSIFIED FINANCIAL SERVICES (4.1%)
 2,403,873 Bank of America Corp. 40,674
 3,629,604 Citigroup, Inc. (f) (17,567)
 1,092,234 JPMorgan Chase & Co. 47,862
 ------------------
 106,103
 ------------------

 PROPERTY & CASUALTY INSURANCE (0.9%)
 149,200 Allstate Corp. 4,568
 95,779 Chubb Corp. 4,828
 47,731 Cincinnati Financial Corp. 1,241
 52,200 MBIA, Inc. * 405
 192,751 Progressive Corp. * 3,196
 158,093 Travelers Companies , Inc. 7,783
 91,600 XL Capital Ltd. "A" 1,599
 ------------------
 23,620
 ------------------

 REAL ESTATE SERVICES (0.0%)
 62,200 CB Richard Ellis Group, Inc. "A" * 730
 ------------------

 REGIONAL BANKS (0.9%)
 188,300 BB&T Corp. 5,129
 222,875 Fifth Third Bancorp 2,258
 59,990 First Horizon National Corp. * 794
 240,440 First Horizon National Corp. - Fractional Shares * -
 157,700 Huntington Bancshares, Inc. 743
 239,300 KeyCorp 1,555
 22,700 M&T Bank Corp. 1,415
 96,799 Marshall & Ilsley Corp. 781
 129,349 PNC Financial Services Group, Inc. 6,285
 327,983 Regions Financial Corp. 2,037
 140,260 SunTrust Banks, Inc. 3,163
 34,400 Zions Bancorp 618
 ------------------
 24,778
 ------------------

 REITS - DIVERSIFIED (0.1%)
 43,090 Vornado Realty Trust 2,775
 ------------------

 REITS - INDUSTRIAL (0.1%)
 126,500 ProLogis 1,508
 ------------------

 REITs - OFFICE (0.1%)
 37,400 Boston Properties, Inc. 2,452
 ------------------

 REITS - RESIDENTIAL (0.2%)
 34,660 Apartment Investment & Management Co. "A" 511
 21,027 AvalonBay Communities, Inc. 1,530
 77,589 Equity Residential Properties Trust 2,382
 ------------------
 4,423
 ------------------

 REITS - RETAIL (0.3%)
 104,268 Kimco Realty Corp. 1,360
 78,829 Simon Property Group, Inc. 5,473
 ------------------
 6,833
 ------------------

 REITS - SPECIALIZED (0.4%)
 80,297 HCP, Inc. 2,308
 32,236 Health Care REIT, Inc. 1,342
 171,400 Host Hotels & Resorts, Inc. 2,017
 45,600 Plum Creek Timber Co., Inc. (g) (1,397)
 38,011 Public Storage 2,860
 44,555 Ventas, Inc. 1,715
 ------------------
 11,639
 ------------------

 SPECIALIZED FINANCE (0.4%)
 18,500 CME Group, Inc. 5,702
 20,400 IntercontinentalExchange, Inc. * 1,983
 53,100 Moody's Corp. 1,086
 40,200 Nasdaq OMX Group, Inc. * 846
 74,100 NYSE Euronext 2,141
 ------------------
 11,758
 ------------------

 THRIFTS & MORTGAGE FINANCE (0.1%)
 133,557 Hudson City Bancorp, Inc. 1,756

PORTFOLIO OF INVESTMENTS (continued) 7
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)


NUMBER
OF SHARES SECURITY MARKET VALUE (000)
----------- -------- ------------------

 95,100 People's United Financial, Inc. 1,480
 ------------------
 3,236
 ------------------
 Total Financials 394,779
 ------------------

 HEALTH CARE (13.0%)
 -------------------
 BIOTECHNOLOGY (1.7%)
 282,961 Amgen, Inc. * 17,043
 80,710 Biogen Idec, Inc. * 4,077
 127,400 Celgene Corp. * 7,122
 19,500 Cephalon, Inc. * 1,136
 75,800 Genzyme Corp. * 4,300
 251,064 Gilead Sciences, Inc. * 11,694
 ------------------
 45,372
 ------------------

 HEALTH CARE DISTRIBUTORS (0.4%)
 81,143 AmerisourceBergen Corp. 1,816
 97,415 Cardinal Health, Inc. 2,611
 73,999 McKesson Corp. 4,406
 27,600 Patterson Companies, Inc. * 752
 ------------------
 9,585
 ------------------

 HEALTH CARE EQUIPMENT (1.9%)
 167,127 Baxter International, Inc. 9,528
 67,000 Becton, Dickinson & Co. 4,673
 412,000 Boston Scientific Corp. * 4,363
 26,800 C.R. Bard, Inc. 2,107
 48,707 Carefusion Corp. * 1,062
 46,316 Hospira, Inc. * 2,066
 10,800 Intuitive Surgical, Inc. * 2,832
 305,637 Medtronic, Inc. 11,247
 94,700 St. Jude Medical, Inc. * 3,694
 79,018 Stryker Corp. 3,590
 33,300 Varian Medical Systems, Inc. * 1,403
 58,574 Zimmer Holdings, Inc. * 3,131
 ------------------
 49,696
 ------------------

 HEALTH CARE FACILITIES (0.0%)
 124,300 Tenet Healthcare Corp. * 731
 ------------------

 HEALTH CARE SERVICES (0.7%)
 28,000 DaVita, Inc. * 1,586
 76,324 Express Scripts, Inc. * 5,921
 30,100 Laboratory Corp. of America Holdings * 1,978
 131,286 Medco Health Solutions, Inc. * 7,261
 44,845 Quest Diagnostics, Inc. 2,341
 ------------------
 19,087
 ------------------

 HEALTH CARE SUPPLIES (0.1%)
 40,000 DENTSPLY International, Inc. 1,382
 ------------------

 HEALTH CARE TECHNOLOGY (0.0%)
 51,300 IMS Health, Inc. 787
 ------------------

 LIFE SCIENCES TOOLS & SERVICES (0.4%)
 48,523 Life Technologies Corp. * 2,259
 14,400 Millipore Corp. * 1,013
 32,900 PerkinElmer, Inc. 633
 113,495 Thermo Fisher Scientific, Inc. * 4,956
 27,700 Waters Corp. * 1,547
 ------------------
 10,408
 ------------------

 MANAGED HEALTH CARE (0.9%)
 119,886 Aetna, Inc. 3,337
 77,710 CIGNA Corp. 2,183
 40,880 Coventry Health Care, Inc. * 816
 45,100 Humana, Inc. * 1,682
 323,450 UnitedHealth Group, Inc. 8,099
 131,530 WellPoint, Inc. * 6,229
 ------------------
 22,346
 ------------------

 PHARMACEUTICALS (6.9%)
 430,301 Abbott Laboratories 21,287
 86,462 Allergan, Inc. 4,908
 552,300 Bristol-Myers Squibb Co. 12,438

PORTFOLIO OF INVESTMENTS (continued) 8
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)


NUMBER
OF SHARES SECURITY MARKET VALUE (000)
----------- -------- ------------------


 280,900 Eli Lilly and Co. 9,278
 81,700 Forest Laboratories, Inc. * 2,405
 765,591 Johnson & Johnson 46,617
 65,400 King Pharmaceuticals, Inc. * 704
 586,900 Merck & Co., Inc. 18,564
 86,700 Mylan, Inc. * 1,388
 1,877,546 Pfizer, Inc. (f) (31,074)
 453,100 Schering-Plough Corp. 12,800
 28,800 Watson Pharmaceuticals, Inc. * 1,055
 371,000 Wyeth 18,023
 ------------------
 180,541
 ------------------
 Total Health Care 339,935
 ------------------

 INDUSTRIALS (10.1%)
 -------------------
 AEROSPACE & DEFENSE (2.7%)
 202,500 Boeing Co. 10,965
 105,995 General Dynamics Corp. 6,847
 35,294 Goodrich Corp. 1,918
 208,300 Honeywell International, Inc. 7,738
 51,535 ITT Corp. 2,688
 32,000 L-3 Communications Holdings, Inc. 2,570
 90,300 Lockheed Martin Corp. 7,051
 87,197 Northrop Grumman Corp. 4,513
 38,300 Precision Castparts Corp. 3,902
 107,653 Raytheon Co. 5,164
 45,278 Rockwell Collins, Inc. 2,300
 262,500 United Technologies Corp. 15,994
 ------------------
 71,650
 ------------------

 AIR FREIGHT & LOGISTICS (1.0%)
 47,100 C.H. Robinson Worldwide, Inc. 2,720
 56,326 Expeditors International of Washington, Inc. 1,980
 85,682 FedEx Corp. 6,445
 277,268 United Parcel Service, Inc. "B" 15,657
 ------------------
 26,802
 ------------------

 AIRLINES (0.1%)
 199,600 Southwest Airlines Co. 1,916
 ------------------

 BUILDING PRODUCTS (0.0%)
 100,000 Masco Corp. 1,292
 ------------------

 COMMERCIAL PRINTING (0.0%)
 56,900 R.R. Donnelley & Sons Co. 1,210
 ------------------

 CONSTRUCTION & ENGINEERING (0.2%)
 49,400 Fluor Corp. 2,512
 33,000 Jacobs Engineering Group, Inc. * 1,516
 53,500 Quanta Services, Inc. * 1,184
 ------------------
 5,212
 ------------------

 CONSTRUCTION & FARM MACHINERY & HEAVY TRUCKS (0.8%)
 172,383 Caterpillar, Inc. 8,848
 57,633 Cummins, Inc. 2,583
 116,200 Deere & Co. 4,987
 101,700 PACCAR, Inc. 3,835
 ------------------
 20,253
 ------------------

 DIVERSIFIED SUPPORT SERVICES (0.1%)
 36,500 Cintas Corp. 1,106
 49,200 Iron Mountain, Inc. * 1,312
 ------------------
 2,418
 ------------------

 ELECTRICAL COMPONENTS & EQUIPMENT (0.4%)
 208,900 Emerson Electric Co. 8,373
 39,500 Rockwell Automation, Inc. 1,682
 ------------------
 10,055
 ------------------

 ENVIRONMENTAL & FACILITIES SERVICES (0.3%)
 91,935 Republic Services, Inc. 2,443
 23,000 Stericycle, Inc. * 1,114
 138,800 Waste Management, Inc. 4,139
 ------------------
 7,696
 ------------------

 HUMAN RESOURCE & EMPLOYMENT SERVICES (0.1%)

PORTFOLIO OF INVESTMENTS (continued) 9
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)


NUMBER
OF SHARES SECURITY MARKET VALUE (000)
----------- -------- ------------------


 32,200 Monster Worldwide, Inc. * 563
 43,100 Robert Half International, Inc. 1,078
 ------------------
 1,641
 ------------------

 INDUSTRIAL CONGLOMERATES (2.4%)
 193,800 3M Co. 14,302
 2,952,815 General Electric Co. (f) (48,485)
 71,800 Textron, Inc. 1,363
 ------------------
 64,150
 ------------------

 INDUSTRIAL MACHINERY (0.8%)
 72,895 Danaher Corp. 4,907
 50,600 Dover Corp. 1,961
 45,300 Eaton Corp. 2,564
 16,300 Flowserve Corp. 1,606
 105,384 Illinois Tool Works, Inc. 4,501
 34,507 Pall Corp. 1,114
 45,100 Parker-Hannifin Corp. 2,338
 18,082 Snap-On, Inc. 629
 20,500 Stanley Works 875
 ------------------
 20,495
 ------------------

 OFFICE SERVICES & SUPPLIES (0.1%)
 32,718 Avery Dennison Corp. 1,178
 57,200 Pitney Bowes, Inc. 1,422
 ------------------
 2,600
 ------------------

 RAILROADS (0.9%)
 72,433 Burlington Northern Santa Fe Corp. 5,782
 110,100 CSX Corp. 4,609
 100,441 Norfolk Southern Corp. 4,330
 141,073 Union Pacific Corp. 8,232
 ------------------
 22,953
 ------------------

 RESEARCH & CONSULTING SERVICES (0.1%)
 14,500 Dun & Bradstreet Corp. 1,092
 35,700 Equifax, Inc. 1,041
 ------------------
 2,133
 ------------------

 TRADING COMPANIES & DISTRIBUTORS (0.1%)
 36,400 Fastenal Co. (g) (1,409)
 18,100 W.W. Grainger, Inc. 1,617
 ------------------
 3,026
 ------------------

 TRUCKING (0.0%)
 15,500 Ryder System, Inc. 606
 ------------------
 Total Industrials 266,108
 ------------------

 INFORMATION TECHNOLOGY (18.5%)
 ------------------------------
 APPLICATION SOFTWARE (0.5%)
 146,700 Adobe Systems, Inc. * 4,847
 61,900 Autodesk, Inc. * 1,473
 52,297 Citrix Systems, Inc. * 2,052
 57,718 Compuware Corp. * 423
 90,000 Intuit, Inc. * 2,565
 30,416 salesforce.com, Inc. * 1,731
 ------------------
 13,091
 ------------------

 COMMUNICATIONS EQUIPMENT (2.7%)
 28,942 Ciena Corp. * 471
 1,604,021 Cisco Systems, Inc. * 37,759
 35,100 Harris Corp. 1,320
 59,625 JDS Uniphase Corp. * 424
 144,200 Juniper Networks, Inc. * 3,896
 645,076 Motorola, Inc. 5,541
 460,300 QUALCOMM, Inc. 20,704
 118,800 Tellabs, Inc. * 822
 ------------------
 70,937
 ------------------

 COMPUTER HARDWARE (5.0%)
 248,692 Apple, Inc. * 46,100
 476,600 Dell, Inc. * 7,273
 659,011 Hewlett-Packard Co. 31,112
 363,977 International Business Machines Corp. 43,535

PORTFOLIO OF INVESTMENTS (continued) 10
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)


NUMBER
OF SHARES SECURITY MARKET VALUE (000)
----------- -------- ------------------

 208,900 Sun Microsystems, Inc. * 1,899
 47,700 Teradata Corp. * 1,313
 ------------------
 131,232
 ------------------

 COMPUTER STORAGE & PERIPHERALS (0.6%)
 562,113 EMC Corp. * 9,578
 21,600 Lexmark International, Inc. "A" * 465
 92,300 NetApp, Inc. * 2,463
 32,900 QLogic Corp. * 566
 63,000 SanDisk Corp. * 1,367
 61,100 Western Digital Corp. * 2,232
 ------------------
 16,671
 ------------------

 DATA PROCESSING & OUTSOURCED SERVICES (1.0%)
 27,200 Affiliated Computer Services, Inc. "A" * 1,473
 141,400 Automatic Data Processing, Inc. 5,557
 43,234 Computer Sciences Corp. * 2,279
 35,500 Convergys Corp. * 353
 55,871 Fidelity National Information Services, Inc. 1,425
 41,951 Fiserv, Inc. * 2,022
 26,754 MasterCard, Inc. "A" 5,408
 91,100 Paychex, Inc. 2,647
 50,155 Total System Services, Inc. 808
 190,799 Western Union Co. 3,610
 ------------------
 25,582
 ------------------

 ELECTRONIC COMPONENTS (0.3%)
 48,000 Amphenol Corp. "A" 1,809
 433,600 Corning, Inc. 6,638
 ------------------
 8,447
 ------------------

 ELECTRONIC EQUIPMENT & INSTRUMENTS (0.2%)
 96,200 Agilent Technologies, Inc. * 2,677
 44,737 FLIR Systems, Inc. * 1,252
 ------------------
 3,929
 ------------------

 ELECTRONIC MANUFACTURING SERVICES (0.1%)
 51,500 Jabil Circuit, Inc. 691
 36,800 Molex, Inc. 768
 ------------------
 1,459
 ------------------

 HOME ENTERTAINMENT SOFTWARE (0.1%)
 92,000 Electronic Arts, Inc. * 1,753
 ------------------

 INTERNET SOFTWARE & SERVICES (1.9%)
 46,700 Akamai Technologies, Inc. * 919
 312,212 eBay, Inc. * 7,371
 66,814 Google, Inc. "A" * 33,130
 54,400 VeriSign, Inc. * 1,289
 331,849 Yahoo!, Inc. * 5,910
 ------------------
 48,619
 ------------------

 IT CONSULTING & OTHER SERVICES (0.1%)
 83,100 Cognizant Technology Solutions Corp. "A" * 3,213
 ------------------

 OFFICE ELECTRONICS (0.1%)
 240,100 Xerox Corp. 1,858
 ------------------

 SEMICONDUCTOR EQUIPMENT (0.3%)
 367,500 Applied Materials, Inc. 4,925
 46,400 KLA-Tencor Corp. 1,664
 60,700 MEMC Electronic Materials, Inc. * 1,009
 30,400 Novellus Systems, Inc. * 638
 53,300 Teradyne, Inc. * 493
 ------------------
 8,729
 ------------------

 SEMICONDUCTORS (2.2%)
 152,400 Advanced Micro Devices, Inc. * 863
 77,885 Altera Corp. 1,597
 78,300 Analog Devices, Inc. 2,159
 117,850 Broadcom Corp. "A" * 3,617
 1,550,091 Intel Corp. 30,335
 63,800 Linear Technology Corp. 1,763
 180,300 LSI Corp. * 990
 51,100 Microchip Technology, Inc. (g) 1,354

PORTFOLIO OF INVESTMENTS (continued) 11
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)


NUMBER
OF SHARES SECURITY MARKET VALUE (000)
----------- -------- ------------------

 244,247 Micron Technology, Inc. * 2,003
 63,330 National Semiconductor Corp. 904
 156,560 NVIDIA Corp. * 2,353
 353,200 Texas Instruments, Inc. 8,367
 79,200 Xilinx, Inc. 1,855
 ------------------
 58,160
 ------------------

 SYSTEMS SOFTWARE (3.4%)
 51,500 BMC Software, Inc. * 1,933
 113,296 CA, Inc. 2,491
 41,900 McAfee, Inc. * 1,835
 2,151,719 Microsoft Corp. 55,708
 87,600 Novell, Inc. * 395
 1,083,392 Oracle Corp. 22,578
 52,304 Red Hat, Inc. * 1,446
 229,789 Symantec Corp. * 3,784
 ------------------
 90,170
 ------------------
 ------------------
 Total Information Technology 483,850
 ------------------

 MATERIALS (3.5%)
 ----------------
 ALUMINUM (0.1%)
 268,100 Alcoa, Inc. 3,517
 ------------------

 CONSTRUCTION MATERIALS (0.1%)
 36,007 Vulcan Materials Co. 1,947
 ------------------

 DIVERSIFIED CHEMICALS (0.8%)
 316,500 Dow Chemical Co. 8,251
 248,875 E.I. du Pont de Nemours & Co. 7,999
 20,600 Eastman Chemical Co. 1,103
 20,100 FMC Corp. 1,131
 46,305 PPG Industries, Inc. 2,695
 ------------------
 21,179
 ------------------

 DIVERSIFIED METALS & MINING (0.3%)
 114,133 Freeport-McMoRan Copper & Gold, Inc. 7,831
 22,800 Titanium Metals Corp. 218
 ------------------
 8,049
 ------------------

 FERTILIZERS & AGRICULTURAL CHEMICALS (0.5%)
 13,900 CF Industries Holdings, Inc. 1,199
 152,314 Monsanto Co. 11,789
 ------------------
 12,988
 ------------------

 FOREST PRODUCTS (0.1%)
 59,008 Weyerhaeuser Co. 2,163
 ------------------

 GOLD (0.2%)
 137,683 Newmont Mining Corp. 6,061
 ------------------

 INDUSTRIAL GASES (0.5%)
 58,794 Air Products & Chemicals, Inc. 4,561
 22,609 Airgas, Inc. 1,094
 84,700 Praxair, Inc. 6,919
 ------------------
 12,574
 ------------------

 METAL & GLASS CONTAINERS (0.2%)
 26,300 Ball Corp. 1,294
 45,800 Owens-Illinois, Inc. * 1,690
 34,000 Pactiv Corp. * 886
 ------------------
 3,870
 ------------------

 PAPER PACKAGING (0.1%)
 30,166 Bemis Co., Inc. 782
 42,700 Sealed Air Corp. 838
 ------------------
 1,620
 ------------------

 PAPER PRODUCTS (0.1%)
 122,920 International Paper Co. 2,733
 46,411 MeadWestvaco Corp. 1,035
 ------------------
 3,768
 ------------------

 SPECIALTY CHEMICALS (0.2%)
 65,301 Ecolab, Inc. 3,019
 21,200 International Flavors & Fragrances, Inc. 804

PORTFOLIO OF INVESTMENTS (continued) 12
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)


NUMBER
OF SHARES SECURITY MARKET VALUE (000)
----------- -------- ------------------

 34,800 Sigma-Aldrich Corp. 1,878
 ------------------
 5,701
 ------------------

 STEEL (0.3%)
 32,200 AK Steel Holding Corp. 635
 27,100 Allegheny Technologies, Inc. 948
 87,100 Nucor Corp. 4,095
 39,100 United States Steel Corp. 1,735
 ------------------
 7,413
 ------------------
 Total Materials 90,850
 ------------------

 TELECOMMUNICATION SERVICES (3.1%)
 ---------------------------------
 INTEGRATED TELECOMMUNICATION SERVICES (2.8%)
 1,640,965 AT&T, Inc. 44,322
 82,114 CenturyTel, Inc. 2,759
 82,200 Frontier Communications Corp. 620
 420,100 Qwest Communications International, Inc. (g) (1,600)
 789,060 Verizon Communications, Inc. 23,885
 119,531 Windstream Corp. 1,211
 ------------------
 74,397
 ------------------

 WIRELESS TELECOMMUNICATION SERVICES (0.3%)
 108,208 American Tower Corp. "A" * 3,939
 70,100 MetroPCS Communications, Inc. * 656
 793,639 Sprint Nextel Corp. * 3,135
 ------------------
 7,730
 ------------------
 ------------------
 Total Telecommunication Services 82,127
 ------------------

 UTILITIES (3.7%)
 ----------------
 ELECTRIC UTILITIES (1.9%)
 49,300 Allegheny Energy, Inc. 1,308
 130,687 American Electric Power Co., Inc. 4,050
 88,216 Edison International 2,962
 53,726 Entergy Corp. 4,291
 184,300 Exelon Corp. 9,145
 83,509 FirstEnergy Corp. 3,818
 114,600 FPL Group, Inc. 6,329
 50,933 Northeast Utilities 1,209
 64,409 Pepco Holdings, Inc. 958
 30,092 Pinnacle West Capital Corp. 988
 106,197 PPL Corp. 3,222
 76,100 Progress Energy, Inc. 2,972
 219,700 Southern Co. 6,958
 ------------------
 48,210
 ------------------

 GAS UTILITIES (0.1%)
 35,200 EQT Corp. 1,499
 14,700 Nicor, Inc. 538
 46,500 Questar Corp. 1,747
 ------------------
 3,784
 ------------------

 INDEPENDENT POWER PRODUCERS & ENERGY TRADERS (0.2%)
 181,500 AES Corp. * 2,690
 57,229 Constellation Energy Group, Inc. 1,852
 135,221 Dynegy, Inc. "A" * 345
 ------------------
 4,887
 ------------------

 MULTI-UTILITIES (1.5%)
 67,234 Ameren Corp. 1,700
 110,746 CenterPoint Energy, Inc. 1,377
 57,902 CMS Energy Corp. 776
 74,847 Consolidated Edison, Inc. 3,064
 166,190 Dominion Resources, Inc. 5,734
 46,985 DTE Energy Co. 1,651
 356,880 Duke Energy Corp. 5,617
 19,300 Integrys Energy Group, Inc. 693
 73,559 NiSource, Inc. 1,022
 102,600 PG&E Corp. 4,154
 142,000 Public Service Enterprise Group, Inc. 4,464
 32,300 SCANA Corp. 1,127
 66,633 Sempra Energy 3,319

PORTFOLIO OF INVESTMENTS (continued) 13
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)


NUMBER
OF SHARES SECURITY MARKET VALUE (000)
----------- -------- ------------------

 63,412 TECO Energy, Inc. 893
 31,500 Wisconsin Energy Corp. 1,423
 127,922 Xcel Energy, Inc. 2,461
 ------------------
 39,475
 ------------------
 Total Utilities 96,356
 ------------------
 Total Common Stocks (cost: $2,591,866) 2,593,005
 ------------------


 MONEY MARKET INSTRUMENTS (0.9%)

 MONEY MARKET FUND (0.6%)
 16,499,377 Northern Institutional Funds - Diversified Assets Portfolio, 0.10% (a),(d) (16,499)
 ------------------

PRINCIPAL
AMOUNT
(000)
-----------
 U.S. TREASURY BILLS (0.3%)
$ 6,470 0.27%, 11/19/2009 (b),(e) (6,468)
 ------------------
 Total Money Market Instruments (cost: $22,967) 22,967
 ------------------

 Number
of Shares
-----------
 SHORT-TERM INVESTMENTS PURCHASED WITH CASH COLLATERAL
 FROM SECURITIES LOANED (0.3%)

 MONEY MARKET FUNDS (0.3%)
 1,477,356 AIM Short-Term Investment Co. Liquid Assets Portfolio, 0.28%(a) 1,477
 7,641,127 BlackRock Provident Liquidity Institutional Temp Fund, 0.22%(a) 7,641
 ------------------
 Total Money Market Funds 9,118
 ------------------

 PRINCIPAL
 AMOUNT
 (000)
-----------
 REPURCHASE AGREEMENTS (0.0%)

 $500 Credit Suisse First Boston LLC, 0.05%, acquired on 9/30/2009 and due
 10/01/2009 at $500 (collateralized by $515 of U.S. Treasury, 0.28%(h), 500
 due 6/17/2010; market value $514) 200
 Deutsche Bank Securities, Inc., 0.06%, acquired on 9/30/2009 and due
 10/01/2009 at $200 (collateralized by $205 of Federal Home Loan
 Bank(i), 0.55%, due 6/30/2010; market value $205) 200
 ------------------
 Total Repurchase Agreements 700
 ------------------
 Total Short-Term Investments Purchased With Cash Collateral From
 Securities Loaned (cost: 9,818) 9,818
 ------------------
 TOTAL INVESTMENTS (COST: $2,624,651) $ 2,625,790
 ==================

PORTFOLIO OF INVESTMENTS (continued) 14
USAA S&P 500 INDEX FUND
September 30, 2009 (unaudited)


 ($ IN 000'S) VALUATION HIERARCHY
 (LEVEL 1) (LEVEL 2) (LEVEL 3)
 QUOTED PRICES IN SIGNIFICANT
 ACTIVE MARKETS FOR OTHER SIGNIFICANT UNOBSERVABLE
 IDENTICAL ASSETS OBSERVABLE INPUTS INPUTS TOTAL
----------------------------------------------------------------------------------------------------------------------
 Common Stocks $ 2,593,005 $ - $ - $ 2,593,005
Money Market Instruments
 Money Market Fund 16,499 - - 16,499
 U.S. Treasury Bills - 6,468 - 6,468
Short-Term Investments Purchased with
Cash Collateral from Securities Loaned:
 Money Market Fund 9,118 9,118
 Repurchase Agreements 700 700
Other Financial Instruments* 446 446
----------------------------------------------------------------------------------------------------------------------
TOTAL $ 2,619,068 $ 7,168 $ - $ 2,626,236
----------------------------------------------------------------------------------------------------------------------

*Other financial instruments are derivative instruments not reflected in the portfolio of investments,
such as futures, which are valued at the unrealized appreciation/depreciation on the investment.



NOTES TO PORTFOLIO
OF INVESTMENTS

September 30, 2009 (unaudited)

GENERAL NOTES

USAA MUTUAL FUNDS TRUST (the Trust), registered under the Investment Company Act of 1940 (the 1940 Act), as amended, is an open-end management investment company organized as a Delaware statutory trust consisting of 45 separate funds. The information presented in this quarterly report pertains only to the USAA S&P 500 Index Fund (the Fund), which is classified as diversified under the 1940 Act.

The Fund has two classes of shares: Member Shares and Reward Shares. Each class of shares has equal rights to assets and earnings, except that each class bears certain class-related expenses specific to the particular class. These expenses include administration and servicing fees, transfer agency fees, postage, shareholder reporting fees, and certain registration and custodian fees. Expenses not attributable to a specific class, income, and realized gains or losses on investments are allocated to each class of shares based on each class's relative net assets. Each class has exclusive voting rights on matters related solely to that class and separate voting rights on matters that relate to both classes.

A. SECURITY VALUATION - The value of each security is determined (as of the close of trading on the New York Stock Exchange (NYSE) on each business day the NYSE is open) as set forth below:

1. Equity securities, including exchange-traded funds (ETFs), except as otherwise noted, traded primarily on a domestic securities exchange or the Nasdaq over-the-counter markets are valued at the last sales price or official closing price on the exchange or primary market on which they trade. If no last sale or official closing price is reported or available, the average of the bid and asked prices generally is used.

2. Investments in open-end investment companies, hedge, or other funds, other than ETFs, are valued at their net asset value (NAV) at the end of each business day.

3. Futures are valued based upon the last sale price at the close of market on the principal exchange on which they are traded.

4. Debt securities purchased with original or remaining maturities of 60 days or less may be valued at amortized cost, which approximates market value.

5. Debt securities with maturities greater than 60 days are valued each business day by a pricing service (the Service) approved by the Trust's Board of Trustees. The Service uses an evaluated mean between quoted bid and asked prices or the last sales price to price securities when, in the Service's judgment, these prices are readily available and are representative of the securities' market values. For many securities, such prices are not readily available. The Service generally prices these


15 | USAA S&P 500 Index Fund


securities based on methods that include consideration of yields or prices of securities of comparable quality, coupon, maturity, and type; indications as to values from dealers in securities; and general market conditions.

6. Repurchase agreements are valued at cost, which approximates market value.

7. Securities for which market quotations are not readily available or are considered unreliable, or whose values have been materially affected by events occurring after the close of their primary markets but before the pricing of the Fund, are valued in good faith at fair value, using methods determined by USAA Investment Management Company (the Manager), an affiliate of the Fund, in consultation with the Fund's subadviser, if applicable, under valuation procedures approved by the Trust's Board of Trustees. The effect of fair value pricing is that securities may not be priced on the basis of quotations from the primary market in which they are traded and the actual price realized from the sale of a security may differ materially from the fair value price. Valuing these securities at fair value is intended to cause the Fund's NAV to be more reliable than it otherwise would be.

Fair value methods used by the Manager include, but are not limited to, obtaining market quotations from secondary pricing services, broker-dealers, or widely used quotation systems. General factors considered in determining the fair value of securities include fundamental analytical data, the nature and duration of any restrictions on disposition of the securities, and an evaluation of the forces that influenced the market in which the securities are purchased and sold.

B. FAIR VALUE MEASUREMENTS - Fair value is defined as the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date. The three-level valuation hierarchy disclosed in the portfolio of investments is based upon the transparency of inputs to the valuation of an asset or liability as of the measurement date. The three levels are defined as follows:

Level 1 - inputs to the valuation methodology are quoted prices (unadjusted) in active markets for identical securities.

Level 2 - inputs to the valuation methodology are other significant observable inputs, including quoted prices for similar securities, inputs that are observable for the securities, either directly or indirectly, and market-corroborated inputs such as market indices.

Level 3 - inputs to the valuation methodology are unobservable and significant to the fair value measurement, including the Manager's own assumptions in determining the fair value.

The inputs or methodologies used for valuing securities are not necessarily an indication of the risks associated with investing in those securities.

C. FUTURES CONTRACTS - The Fund is subject to cash flow and tracking error risk in the normal course of pursuing its investment objectives. The Fund may use stock index futures contracts in an attempt to reduce any performance discrepancies between the Fund and the S&P 500 Index. A futures contract represents a commitment for the future purchase or sale of an asset at a specified price on a specified date. Upon entering into such contracts, the Fund is required to deposit with the broker in


Notes to Portfolio of Investments | 16


either cash or securities an initial margin in an amount equal to a certain percentage of the contract amount. Subsequent payments (variation margin) are made or received by the Fund each day, depending on the daily fluctuations in the value of the contract, and are recorded for financial statement purposes as unrealized gains or losses. When the contract is closed, the Fund records a realized gain or loss equal to the difference between the value of the contract at the time it was opened and the value at the time it was closed. Upon entering into such contracts, the Fund bears the risk of interest or exchange rates or securities prices moving unexpectedly in an unfavorable direction, in which case, the Fund may not achieve the anticipated benefits of the futures contracts.

D. LENDING OF PORTFOLIO SECURITIES - The Fund, through its third-party securities-lending agent, Wachovia Global Securities Lending, may lend its securities to qualified financial institutions, such as certain broker-dealers, to earn additional income. The borrowers are required to secure their loans continuously with cash collateral in an amount at least equal to the fair value of the securities loaned, initially in an amount at least equal to 102% of the fair value of domestic securities loaned and 105% of the fair value of international securities loaned. Cash collateral is invested in high-quality short-term investments. Cash collateral requirements are determined daily based on the prior business day's ending value of securities loaned. Imbalances in cash collateral may occur on days where market volatility causes security prices to change significantly, and are adjusted the next business day. Risks to the Fund in securities-lending transactions are that the borrower may not provide additional collateral when required or return the securities when due, and that the value of the short-term investments will be less than the amount of cash collateral required to be returned to the borrower. The aggregate fair market value of the loaned portion of these securities as of September 30, 2009, was approximately $9,616,000.

E. SUBSEQUENT EVENTS - Subsequent events are events or transactions that occur after the balance sheet date but before the quarterly report is issued and are categorized as recognized or non-recognized for quarterly report purposes. The Manager has evaluated subsequent events through November 19, 2009, the date the quarterly report was issued, and has determined there were no events that required recognition or disclosure in the Fund's quarterly report.

F. As of September 30, 2009, the cost of securities, for federal income tax purposes, was approximately the same as that reported in the portfolio of investments. Gross unrealized appreciation and depreciation of investments as of September 30, 2009, were $573,073,000 and $571,934,000, respectively, resulting in net unrealized appreciation of $1,139,000.

G. The portfolio of investments category percentages shown represent the percentages of the investments to net assets, which were $2,618,997,000 at September 30, 2009, and, in total, may not equal 100%. A category percentage of 0.0% represents less than 0.1% of net assets.

PORTFOLIO ABBREVIATIONS AND DESCRIPTIONS

REIT - Real estate investment trust

SPECIFIC NOTES

(a) Rate represents the money market fund annualized seven-day yield at September 30, 2009.


17 | USAA S&P 500 Index Fund


(b) Rate represents an annualized yield at time of purchase, not a coupon rate.

(c) Northern Trust Corp. is the parent to Northern Trust Investments, N.A. (NTI), which is the subadviser of the Fund.

(d) NTI is both the subadviser of the Fund and the adviser of the Northern Institutional Funds.

(e) Security with a value of $6,468,000 is segregated as collateral for initial margin requirements on open futures contracts.

(f) Security, or a portion thereof, is segregated to cover the value of open futures contracts at September 30, 2009, as shown in the following table:

 VALUE AT
 ------------------------------ UNREALIZED
TYPE OF FUTURE EXPIRATION CONTRACTS POSITION TRADE DATE SEPTEMBER 30, APPRECIATION
 2009
-----------------------------------------------------------------------------------------------
S&P 500 Index December 18, 98 Long $25,350,000 $25,796,000 $446,000
Futures 2009

(g) The security or a portion thereof was out on loan as of September 30, 2009.

(h) Zero-coupon security. Rate represents the effective yield at the date of purchase.

(i) Securities issued by government-sponsored enterprises (GSEs) are supported only by the right of the GSE to borrow from the U.S. Treasury, the discretionary authority of the U.S. government to purchase the GSEs' obligations, or by the credit of the issuing agency, instrumentality, or corporation, and are neither issued nor guaranteed by the U.S. Treasury.

* Non-income producing security.


Notes to Portfolio of Investments | 18

ITEM 2. CONTROLS AND PROCEDURES

The principal executive officer and principal financial officer of USAA Mutual Funds Trust (Trust) have concluded that the Trust's disclosure controls and procedures are sufficient to ensure that information required to be disclosed by the Trust in this Form N-Q was recorded, processed, summarized and reported within the time periods specified in the Securities and Exchange Commission's rules and forms, based upon such officers' evaluation of these controls and procedures as of a date within 90 days of the filing date of the report.

There were no significant changes or corrective actions with regard to significant deficiencies or material weaknesses in the Trust's internal controls or in other factors that could significantly affect the Trust's internal controls subsequent to the date of their evaluation.

ITEM 3. EXHIBITS.

Certification pursuant to Rule 30a-2(a) under the Investment Company Act of 1940 (17 CFR 270.30a-2(a)) is filed and attached hereto as Exhibit 99.CERT.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Registrant: USAA MUTUAL FUNDS TRUST - Period Ended September 30, 2009

By:* /s/ CHRISTOPHER P. LAIA
 --------------------------------------------------------------
 Signature and Title: Christopher P. Laia, Assistant Secretary

Date: NOVEMBER 20, 2009
 -------------------------------

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

By:* /s/ CHRISTOPHER W. CLAUS
 -----------------------------------------------------
 Signature and Title: Christopher W. Claus, President

Date: NOVEMBER 23, 2009
 ------------------------------


By:* /s/ ROBERTO GALINDO, JR.
 -----------------------------------------------------
 Signature and Title: Roberto Galindo, Jr., Treasurer

Date: NOVEMBER 23, 2009
 ------------------------------

*PRINT THE NAME AND TITLE OF EACH SIGNING OFFICER UNDER HIS OR HER SIGNATURE.

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