SRNE Sorrento Therapeutics Inc

Sorrento Therapeutics, Inc. (Nasdaq: SRNE, “Sorrento”) today distributed dividend confirmation statements to 146 brokerage firms regarding its recent dividend to Sorrento stockholders of shares of common stock of Scilex Holding Company (Nasdaq: SCLX, “Scilex”) held by Sorrento. These statements, which contain the account numbers and amount of Scilex dividend shares, were previously mailed out by Continental Stock Transfer & Trust Company.

The dividend confirmation statements are being distributed on behalf of Sorrento and Scilex to notify each brokerage firm of Sorrento’s previously announced stock dividend (the “Dividend”) consisting of an aggregate of 76,000,000 shares (the “Dividend Stock”) of common stock of Scilex held by Sorrento to record holders of (i) Sorrento’s common stock (the “Record Common Holders”) as of the close of business on January 9, 2023 (the “Record Date”), and (ii) certain warrants to purchase Sorrento common stock (which have or may have the right to participate in the Dividend pursuant to the terms of their respective warrants).

According to Sorrento’s estimates, approximately 60 million or more shares of Sorrento common stock were sold “short” as of the Record Date. In the event the shares of Sorrento common stock were held through a brokerage firm, bank, dealer or other similar organization and were sold “short” as of the Record Date, holders should consult with their financial advisor, broker or other agent immediately to determine whether they may also be deemed “short” Scilex common stock as a result of the Dividend, as well as any obligations required for you to cover your “short” position(s). Please note that “naked short” sales or “naked short” positions in any Sorrento common stock may constitute a violation of the U.S. Securities and Exchange Commission Regulation SHO.

Each Record Common Holder is entitled to receive 0.1410127 of a share of Scilex common stock for each one share of Sorrento common stock held by such Record Common Holder as of the close of business on the Record Date. The payment date for the Dividend was January 19, 2023. The resulting fewer number of shares of Scilex common stock that will be available to trade could cause the trading market of the common stock of Scilex to become less liquid. As noted above, Scilex’s transfer agent, Continental Stock Transfer & Trust Company (“CST”), has already distributed to brokerage firms, as the Record Common Holder (for the benefit of their customers that held Sorrento common stock on the Record Date), a book-entry/DRS transaction confirmation (the “Dividend Confirmation Statement”) reflecting the portion of the Dividend Stock allocated to such firm (for the benefit of their customers that held Sorrento common stock on the Record Date), which Dividend Confirmation Statements were mailed to the addresses on record with The Depository Trust & Clearing Corporation.

In the event that brokerage firms did not receive copies of the Dividend Confirmation Statements, please contact CST immediately. Sorrento and Scilex are requesting that each brokerage firm distribute the Dividend Stock to the actual beneficial owners thereof and to reflect Scilex’s CUSIP number 80880W106 and value of Scilex common stock on each beneficial owner’s brokerage statement.  

Sorrento and Scilex have given specific instructions to Scilex’s transfer agent, CST, on how to answer certain inquiries from Record Holders and brokerage firms:

• When beneficial holders call CST:
  • CST will direct the beneficial holders to contact their brokers.
• When brokers call CST:
  • CST needs to confirm with the broker that such broker has received their Dividend Confirmation Statement.
  • If brokers did not get the Dividend Confirmation Statement, CST will distribute the Dividend Confirmation Statement again to the applicable broker.
• CST will communicate to the brokers that Sorrento and Scilex demand that brokers distribute the Scilex common stock to the individual accounts of the beneficial holders.
• If brokers refuse to distribute the Scilex common stock, Sorrento and Scilex will work with CST and the beneficial holder in exiting their brokerage accounts out of “street” name and into book entry format with CST so that the beneficial holder becomes the direct holder of record with CST. The beneficial holders will be charged $15 for the exit of such positions from their brokerage accounts.

To obtain a copy of the Dividend Confirmation Statement and to have the Dividend Stock reflected on such Dividend Confirmation Statement further distributed to the actual beneficial owners thereof, please contact Scilex’s transfer agent, CST, by phone or email at:

Continental Stock Transfer & Trust Company Telephone Number: 800-509-5586 Email Address: cstmail@continentalstock.com

Broker List

Broker Name	Broker Address		Broker Name	Broker Address
ABN AMRO CLEARING CHICAGO LLChttps://www.abnamro.com/clearing/en/contact-form	175 WEST JACKSON BLVD. CHICAGOIL ILLINOIS 60604 US		Albert Fried & Company LLCinformation@albertfried.com	45 BROADWAY, 24TH FLOOR24TH FLOOR NEW YORK NY NEW YORK10006 US
AMALGAMATED BANKhttps://www.amalgamatedbank.com/contact	275 7TH AVENUE NEW YORKNY NEW YORK 10003 US		AMERICAN ENTERPRISE INVESTMENT SERVICES INC.contactus@americanenterprise.com	682 AMERIPRISE FINANCIAL CENTER MINNEAPOLISMN MINNESOTA 55474 US

Broker Name	Broker Address		Broker Name	Broker Address
APEX CLEARING CORPORATIONcs@apexclearing.com	2 GATEWAYCENTER 283-299 MARKET ST 16TH FLOOR NEWARKNJ NEW JERSEY 07102-5005 US		BANK OF AMERICA, NA/GWIM TRUST OPERATIONS1.800.878.7878https://www.privatebank.bankofamerica.com/find-an-advisor.html	901 MAIN STREET12TH FLOOR DALLASTX TEXAS 23113 US
BANK OF NEW YORK MELLONgceamericas@bnymellon.com	111 SANDERS CREEK PARKWAY 2ND FLOOR2ND FLOOR EAST SYRACUSE NY NEW YORK 13057 US.		BARCLAYS CAPITAL INC.corporateactionsu@barclays.com	DTC CUSTODY PARTICIPANT- NY WINDOW -570 WASHINGTON BLVD (ATTN: ROSA HICKS- MILLER OR ROBERT MENDEZJERSEY CITY NJ NEW JERSEY07310 US
BARCLAYS CAPITAL INC.corporateactionsu@barclays.com	DTC CUSTODY PARTICIPANT- NY WINDOW -570 WASHINGTON BLVD (ATTN: ROSA HICKS-MILLER OR ROBERT MENDEZ JERSEY CITYNJ NEW JERSEY 07310 US		BMO CAPITAL MARKETS CORP.https://capitalmarkets.bmo.com/en/contact-us/	3 2ND STREET12TH FLOOR JERSEY CITY NJ NEW JERSEY 07302 US
BMO HARRIS BANK NA/TRUSThttps://www.bmoharris.com/main/contact-us/	11270 W PARK PL MILWAUKEEWI WISCONSIN 53224 US		BMO Nesbitt Burns Inc., TorontoNACom.Compliance@bmo.com	250 YONGE STREET,7TH FLOOR7TH FLOOR TORONTO ON ONTARIO M5B 2M8 CACANADA
BNP PARIBAS, NEW YORK BRANCH/BNP PARIBAS PRIMEBROKERAGE CUSTODIANalex.bergelson@us.bnpparibas.com	100 WEST 33RD STREET3RD FLOOR NEW YORK NY NEW YORK10001		BNP PARIBAS, NEW YORK BRANCH/BNP PARIBAS PRIMEBROKERAGE CUSTODIANalex.bergelson@us.bnpparibas.com	100 WEST 33RD STREET3RD FLOOR NEW YORK NY NEW YORK10001
BNY MELLONgceamericas@bnymellon.com	PO BOX 392002500 ROSS STREET PITTSBURGHPAPENNSYLVANIA 15262 US		BNY MELLON/WEALTH MANAGEMENTgceamericas@bnymellon.com	1 FREEDOM VALLEY DRIVEOAKSPA PENNSYLVANIA 19456 US
BNYMELLONgceamericas@bnymellon.com	111 SANDERS CREEK PARKWAY 2ND FLOOR2ND FLOOR EAST SYRACUSE		BNYMELLON/RE BARCLAYS CAPITAL SECURITIES LTD.gceamericas@bnymellon.com	ONE WALL STREET NEW YORKNY NEW YORK 10286

Broker Name	Broker Address		Broker Name	Broker Address
	NY NEW YORK 13057 US
BNYMELLON/RE CACEIS BANK LUXEMBOURGgceamericas@bnymellon.com	500 Grant St.BNY Mellon Center PITTSBURGHPA PENNSYLVANIA15258		BNYMELLON/RE CACEIS BANK, NETHERLANDSgceamericas@bnymellon.com	111 SANDERS CREEK PARKWAYEAST SYRACUSE NY NEW YORK 13057
BNYMELLON/RE CHARLES STANLEY AND COMPANY, LIMITEDgceamericas@bnymellon.com	111 SANDERS CREEK PARKWAY 2ND FLOOR2ND FLOOR EAST SYRACUSE NY NEW YORK13057 US		BNYMELLON/RE ETF - ISHARES DTC/NSCCgceamericas@bnymellon.com	111 SANDERS CREEK PARKWAYEAST SYRACUSE NY NEW YORK 13057
BNYMELLON/RE WINTERFLOOD SECURITIES LTDgceamericas@bnymellon.com	500 Grant St.BNY Mellon Center PITTSBURGHPA PENNSYLVANIA 15258		BOFAcorey.j.colvin@bankofamerica.com	4804 Deer Lake Drive EastFL9-803-04-04- 4thfloor JACKSONVILLE FL FLORIDA32246 US
BOFAcorey.j.colvin@bankofamerica.com	4804 Deer Lake Drive EastFL9-803-04-04- 4thfloor JACKSONVILLE FL FLORIDA32246 US		BOFASECURITIES INCcorey.j.colvin@bankofamerica.com	4804 Deer Lake Drive EastFL9-803-04-04- 4thfloor JACKSONVILLE FL FLORIDA32246 US
BROWN BROTHERS HARRIMAN & CO.contactus@bbh.com	140 BROADWAY ATTN: CORPORATE ACTIONS VAULT NEW YORKNY NEW YORK 10005 US		BROWN BROTHERS HARRIMAN & CO./ETFcontactus@bbh.com	140 BROADWAY NEW YORKNY NEW YORK 10005
CALDWELL SECURITIES LTD./CDS**reception@caldwellsecurities.com	55 UNIVERSITY AVENUESUITE 340 TORONTO ON ONTARIOM5J 2H7 CANADA		CANACCORD GENUITY CORP.investor.relations@cgf.com	609 GRANVILLE ST VANCOUVERBC BRITISH COLUMBIAV7Y 1H2 CA CANADA
CANTOR, FITZGERALD & CO.https://www.cantor.com/investor-center/	135 E 57TH ST 5TH FLNEW YORKNY NEW YORK 10041 US		CDS CLEARING AND DEPOSITORY SERVICES INC.cdscustomersupport@tmx.com	100 ADELAIDE STREET WEST TORONTOON ONTARIOM5H 1S3 CA CANADA
CETERA INVESTMENT SERVICES LLCreorg@ceterafi.com	400 FIRST STREETSOUTH, SUITE 300SUITE 300 ST. CLOUD		CHARLES SCHWAB & CO., INC.800-435-4000https://www.schwab.com/contact-us	211 MAIN STREET SAN FRANCISCO CA CALIFORNIA94105 US

Broker Name	Broker Address		Broker Name	Broker Address
	MN MINNESOTA 56302-0283 US
CI INVESTMENT SERVICES INC.info.ciis@ci.com	199 BAY STREETSUITE 2600 TORONTO ON ONTARIO M5L 1E2 CACANADA		CIBC WORLD MARKETS INC./CDS**info@cibc.com.	161 BAY STREET 10 FLTORONTO ON ONTARIOM5J 2S8 CA CANADA
CITIBANK, N.A./ETF1-800-950-5114	3800 CITIGROUP CENTERB2/2 TAMPAFL FLORIDA 33610		CITIBANK, NATIONAL ASSOCIATION1-800-950-5114	3800 CITIBANK CENTER TAMPA BLDG.B FIRST FLOOR ZONE 8 TAMPAFL FLORIDA 33610-9122 US
CITIGROUP GLOBAL MARKETS, INC.1-800-950-5114	580 CROSSPOINT PARKWAY GETZVILLENY NEW YORK 14068 US		CLEAR STREET LLChttps://clearstreet.io/contact	4 World Trade Center, 45th Floor150 Greenwich Street NEW YORKNY NEW YORK 10007
CLEARSTREET IOinfo@clearstreet.io	55 BROADWAY(SUITE 2102) CORPORATE ACTIONS NEW YORKNEW YORK 10006 US		COMMERCE BANKbrokerage.newaccounts@commercebank.com	922 WALNUT STREET MAIL STOP TBTS-2 KANSAS CITYMO MISSOURI 64106 US
COR CLEARING LLCdividend.interests@axosclearing.com	9300 UNDERWOOD AVESUITE 400 OMAHANE NEBRASKA 68114 US		Credential Securities Inc.clientcare@credential.com	800-1111 WEST GEORGIA STREET VANCOUVERBC BRITISH COLUMBIAV6E 4T6 CA CANADA
CREST INTERNATIONAL NOMINEES LIMITEDAdmin@crest-approved.org	33 CANNON STREET LONDON EC4M 5SB GBUNITED KINGDOM		CURVATURE SECURITIES, LLCinfo@curvaturesecurities.com	39 MAIN STREET CHATHAMNJ NEW JERSEY 07928 US
D.A. DAVIDSON & CO.https://dadavidson.com/Contact-Us	8 3RD STREET NORTH GREAT FALLS MT MONTANA59401 US		DEPOSITO CENTRAL DE VALORES S.A., DEPOSITO DEVALOREShttps://www.dcv.cl/en/contact.html	AVENIDA APOQUINDO # 4001FLOOR 12, C.P.7550162, SANTIAGO CL CHILE

Broker Name	Broker Address		Broker Name	Broker Address
DESJARDINS SECURITIES INC.asfaires@desjardins.com	1253 McGill College 10TH FLOOR MONTREAL QUEBECH3B 2Y5 CA CANADA		DEUTSCHE BANK AG NY/US CUSTODYdeutsche.bank@db.com	1251 Avenue Of The AmericasNEW YORK NY NEW YORK 10020
DEUTSCHE BANK SECURITIES INC.intm.corporate-actions@db.com	60 WALL STREET9TH FLOOR NEW YORK NY NEW YORK 10005 US		DRIVEWEALTH, LLChttps://www.drivewealth.com/lets-build-together/	15 EXCHANGE PLACE10TH FLOOR JERSEY CITYNEW JERSEY 07302
E*TRADE CLEARING LLChttps://us.etrade.com/contact-us	HARBORSIDE FINANCIAL CENTER501 PLAZA 11 JERSEY CITYNJ NEW JERSEY 07311 US		EDWARD D. JONES & CO., L.P.1 (800) 441-2357	12555 MANCHESTER ROADST. LOUISMO MISSOURI 63131-3729 US
EDWARD D. JONES & CO., L.P.1 (800) 441-2357	201 PROGRESS PARKWAY MARYLAND HEIGHTSMO MISSOURI 63043 US		FIDELITY CLEARING CANADAULC/CDS**acctransfer.fcc@fidelity.ca	483 BAY ST. SOUTH TOWER TORONTOON ONTARIO M5G2N7 CA CANADA
FIFTH THIRD BANK1-866-671-5353	5001 KINGSLEY DRIVEMAIL DROP 1MOB28 CINCINNATIOH OHIO 45227 US		FOLIO INVESTMENTS, INC.https://folioinvesting.com/folioinvesting/contact-us/	8180 GREENSBORO DRIVE8TH FLOOR MCLEANVA VIRGINIA 22102 US
FUTU CLEARING INC.customersvc@futuclearing.com	12750 Merit DriveSUITE 475 DALLAS TX TEXAS 75251		GMP SECURITIES L.P.416 943 6696	145 KING STREETWEST, SUITE 300 11TH FLOOR TORONTOON ONTARIOMJ5 1J8 CA CANADA
GOLDMAN, SACHS & CO. LLCgs-investor-relations@gs.com.	222 SOUTH MAIN STREETAttn: Mandatory Corporate Actions SALT LAKE CITY UT UTAH84101 US		HAYWOOD SECURITIES INC./CDS**https://www.haywood.com/who-we-are/locations	200 BURRARD ST WATERFRONT CENTRE SUITE 700 VANCOUVERBC BRITISH COLUMBIAV6C 3L6 CANADA
HILLTOP SECURITIES INC.https://www.hilltopsecurities.com/contact/	1201 ELM ST.35TH FLOOR DALLASTX TEXAS75270 US		HRT FINANCIAL LLCvoicemail@hudson-trading.com	150 GREENWICH STREET (ATTN: SETTLEMENT) FOUR WORLD TRADECENTER

Broker Name	Broker Address		Broker Name	Broker Address
				57TH FLOOR NEW YORK NY NEW YORK10007 US
HSBC BANK USA, NA/HSBC CUSTODY & CLEARING SERVICES FORSTOCK LOANhttps://www.us.hsbc.com/customer-service/contact-us/	452 FIFTH AVENUE ATTN: HBUS CCS SETTSNEW YORK NY NEW YORK10018 US		HSBC BANK USA, NATIONAL ASSOCIATIONinvestorrelations@hsbc.com	452 FIFTH AVENUE ATTN: HBUS CCS SETTSNEW YORK NEW YORK10018 US
INTERACTIVE BROKERS LLC877-442-2757	2 PICKWICK PLAZA2ND FLOOR GREENWICHCT CONNECTICUT06830 US		J.P. MORGAN CHASE BANK NA/FBO BLACKROCK CTFhttps://am.jpmorgan.com/us/en/asset-management/adv/contact-us/	1111 POLARIS PARKWAY COLUMBUS OH OHIO43240
J.P. MORGAN CLEARING CORP.(347) 643-1000	FOUR CHASE METROTECH CENTER3RD FLOOR BROOKLYN NY NEW YORK11201 US		JANNEY MONTGOMERY SCOTT LLCtaxreportingwccontacts@janney.com	1717 ARCH STREET17TH FLOOR PHILADELPHIAPA PENNSYLVANIA 19103 US
JEFFERIES LLChttps://www.jefferies.com/FooterPages/Contact-Us/94	101 HUDSONSTREET, 11th Floor NEW JERSEYNJ NEW JERSEY 07302 US		JPMORGAN CHASE BANK, NATIONAL ASSOCIATIONJPMCinvestorrelations@jpmchase.com	FOUR CHASE METROTECH CENTER3RD FLOOR BROOKLYN NY NEW YORK11201 US
JPMORGAN CHASE BANK/EUROCLEAR BANKJPMCinvestorrelations@jpmchase.com	FOUR CHASE METROTECH CENTER3RD FLOOR BROOKLYN NY NEW YORK11245 US		JPMORGAN CHASE BANK/IAJPMCinvestorrelations@jpmchase.com	FOUR CHASE METROTECH CENTER3RD FLOOR BROOKLYN NY NEW YORK11201 US
KEYBANK NATIONAL ASSOCIATIONhttps://www.key.com/personal/customer-support/contact-us.html	4900 TIEDEMAN RD BROOKLYNOH OHIO 44144 US		LAURENTIAN BANK SECURITIES INC.https://www.vmbl.ca/portal/web/site_public/contactez-nous	1981 MCGILL COLLEGE AVE. SUITE 100 MONTREAL QUEBECH3A 3K3 CA CANADA
LPL FINANCIAL LLCrenata.jaskiewicz@lpl.com	4707 EXECUTIVE DRIVESAN DIEGOCA CALIFORNIA 92121 US		MANUFACTURERS AND TRADERS TRUST COMPANYhttps://www3.mtb.com/homepage/explore-the-m-and-t-bank-help-center/mandt-bank-phone-numbers-by-department/telephone-directory	ONE M&T PLAZA TRUST OPS 8TH FLOOR BUFFALONY NEW YORK 14203 US

Broker Name	Broker Address		Broker Name	Broker Address
MANULIFE SECURITIES INCORPORATEDMLS_securitiesoperations@manulife.ca	1235 NORTH SERVICE ROAD WEST OAKVILLEON ONTARIOL6M 2W2 CA CANADA		MARSCO INVESTMENT CORPORATIONop@tradeup.com	101 EISENHOWER PARKWAY ROSELANDNJ NEW JERSEY 07068 US
MERRILL LYNCH, PIERCE, FENNER & SMITH INCORPORATEDhttps://www.ml.com/contactus/contact-us.html	4804 Deer Lake Drive EastFL9-803-04-04- 4thfloor JACKSONVILLE FL FLORIDA32246 US		MIRAE ASSET SECURITIES (USA) INC./STOCK LOAN CONDUIT ACCOUNT212-407-1000	810 SEVENTH AVE37TH FLOOR NEW YORKNY NEW YORK 10019
MIRAE ASSET SECURITIES (USA), INC.212-407-1000	810 SEVENTH AVE37TH FLOOR NEW YORK NY NEW YORK 10019		MITSUBISHI UFJ TRUST & BANKING CORPORATION, NEW YORKBRANCHhttps://safe.tr.mufg.jp/cgi-bin/english/index_contact/index_contact_01.cgi?r=7	280 PARK AVE39TH FL-WEST BLDG NEW YORKNY NEW YORK 10017
Morgan Stanleyinfo@morganstanley.com	1300 THAMES STREETTHAMES STREET WHARF BALTIMOREMD MARYLAND 21231 US		MORGAN STANLEY & CO. LLCinfo@morganstanley.com	1300 THAMES ST. BALTIMOREMD MARYLAND
MORGAN STANLEY SMITH BARNEY LLCinvestorrelations@morganstanley.com	1 NEW YORK PLAZA39TH FLOOR NEW YORKNY NEW YORK 10004 US		MURIEL SIEBERT & CO., INC.service@siebert.com	77 SUMMER STREET3RD FLOOR BOSTON MAMASSACHUSETTS 02210 US
NATIONAL FINANCIAL SERVICES LLChttp://www.national-financial-services.com/contact_us/	499 WASHINGTON BOULEVARD5TH FLOOR JERSEY CITY NJ NEW JERSEY07310 US		NBCN INC.NBINinformation@nbc.ca	1010 rue De La Gauchetière Mezzanine 100 MONTREAL QUEBECH3B 5J2 CA CANADA
NOMURA INTERNATIONAL TRUST COMPANYhttps://www.nomuraholdings.com/news/contact/	309 WEST 49TH STREET10TH FLOOR NEW YORK NY NEW YORK10019 US		ODLUM BROWN LIMITEDinformation@odlumbrown.com	250 HOWE STREETSUITE 1100 VANCOUVER BC BRITISH COLUMBIAV6C 3R8 CA CANADA
OPPENHEIMER & CO. INC.michael.shih@opco.com	85 BROAD STREET NEW YORKNY NEW YORK 10004 US		PERSHING LLChttps://www.pershing.com/contact/	1 PERSHING PLAZA JERSEY CITYNJ NEW JERSEY 07399 US

Broker Name	Broker Address		Broker Name	Broker Address
PHILLIP CAPITAL INC.corporateactions@phillipcapital.com	141 W. JACKSONBLVD. SUITE 3050 CHICAGOIL ILLINOIS 60604 US		PI FINANCIAL CORP.reorg@pifinancial.com	666 BURRARD STSUITE 1900 VANCOUVER BC BRITISH COLUMBIAV6C 3N1 CA CANADA
PNC BANK, NATIONAL ASSOCIATIONconsumerloans@pnc.com	4100 W 150TH STREETASSET MOVEMENT TEAM 3RD FL, LOCATOR B7- YB17-03-03 CLEVELANDOH OHIO 44135 US		PRINCIPAL BANKhttps://www.principal.com/contact-us	711 HIGH STREET DES MOINESIA IOWA 50392
QUESTRADE INC./CDS**compliance@questrade.com	5650 YONGE ST.,Suite 1700 TORONTO ON ONTARIO M2M 4G3 CACANADA		Raymond James & Associates, Inc.ClientAccessSupport@RaymondJames.com	880 CARILLON PKWY ST. PETERSBURGFL FLORIDA 33733-2749 US
RAYMOND JAMES LTD.corporateactions@raymondjames.com	925 WEST GEORGIA STREET SUITE 2200 VANCOUVERBC BRITISH COLUMBIA V6C 3L2 CACANADA		RBC CAPITAL MARKETS, LLC rbcrundle@rbccm.com	60 SOUTH 6TH ST. MINNEAPOLIS MN MINNESOTA 55402 US
RBC DOMINION SECURITIES INCdsonline@rbc.com	21 COMMERCE COURT SOUTH 2ND FLOOR TORONTOON ONTARIOM5L 1A7 CANADA		RELIANCE TRUST COMPANYhttps://www.reliancetrustgroup.com/contact	1100 ABERNATHY RD.500 NORTHPARKSUITE 400 ATLANTA GA GEORGIA30113 US
RELIANCE TRUST COMPANYjaned@reliance-trust.com	4900 W. BROWN DEER RD MILWAUKEE WI WISCONSIN 53223 US		ROBERT W. BAIRD & CO. INCORPORATEDdividends@rwbaird.com	777 E WISCONSIN AVE9TH FLOOR MILWAUKEE WI WISCONSIN53202 US
ROBINHOOD SECURITIES, LLCir@robinhood.com	500 COLONIAL CENTER PARKWAY SUITE 100 LAKE MARY FL FLORIDA32746 US		SAFRA SECURITIES LLChttps://www.safrasecurities.com/Contact.aspx	546 5TH AVENUE NEW YORKNY NEW YORK 10036 US

Broker Name	Broker Address		Broker Name	Broker Address
SCOTIA CAPITAL (USA) INC.investor.relations@scotiabank.com	150 KING STREET W5TH FLOOR TORONTO ON ONTARIO M5H 1J9 CACANADA		SEI PRIVATE TRUST COMPANYhttps://www.seic.com/contact-us	1 FREEDOM VALLEY DRIVEOAKSPA PENNSYLVANIA 19456 US
SEI PRIVATE TRUST COMPANYhttps://www.seic.com/contact-us	1 FREEDOM VALLEY DRIVE OAKSPA PENNSYLVANIA19456 US		SG AMERICAS SECURITIES, LLChttps://americas.societegenerale.com/en/contact/	480 WASHINGTON BLVD.20TH FLOOR JERSEY CITY NJ NEW JERSEY07310 US
SSB - BLACKROCK INSTITUTIONAL TRUSTgroupcorpcommsamrs@blackrock.com	50 California Street San FranciscoCA CALIFORNIA 94163		SSB - TRUST CUSTODY ssb@dss.ca.gov	30 ADELAIDE ST EASTSUITE 800 TORONTO ON ONTARIO M5C 3G6 CACANADA
SSB&T CO/CLIENT CUSTODY SERVICEShttps://www.ssbtexas.com/contact	1776 HERITAGE DRIVENORTH QUINCY MAMASSACHUSETTS 02171		STATE STREET BANK & TRUST COses-client-service@statestreet.com	16 WALL STREET5TH FLOOR NEW YORKNY NEW YORK 10005 US
STATE STREET BANK & TRUST COMPANY / ISHARES EUROPEses-client-service@statestreet.com	1776 HERITAGE DRIVENORTH QUINCY MA MASSACHUSETTS02171		STATE STREET BANK & TRUST/STATE STREET TOTALETFses-client-service@statestreet.com	1776 Heritage Drive NORTH QUINCY MA MASSACHUSETTS 02717
STATE STREET BANK AND TRUST COMPANYses-client-service@statestreet.com	30 ADELAIDE ST EASTSUITE 800 TORONTO ON ONTARIOM5C 3G6 CA CANADA		STIFEL, NICOLAUS & COMPANY, INCORPORATEDinvestorrelations@stifel.com	501 N BROADWAY ST. LOUISMO MISSOURI 63102 US
STONEX FINANCIAL INC.dg-clre-org_tenders@stonex.com	2 PERIMETER PARK SOUTH SUITE 100 W BIRMINGHAM AL ALABAMA35243 US		TD AMERITRADE CLEARING, INC.https://www.tdameritrade.com/why-td-ameritrade/contact-us.html	200 S 108TH AVE OMAHANE NEBRASKA 68154 US
TD WATERHOUSE CANADA INC ATTN: MANDATORYhttps://www.tdameritrade.com/why-td-ameritrade/contact-us.html	77 BLOOR STREET WEST3RD FLOOR TORONTOON ONTARIOM5S 1M2 CA CANADA		TEXAS TREASURY SAFEKEEPING TRUST COMPANYmathewwilliams@ttstc.org	208 E 10TH ST AUSTINTX TEXAS 78701 US

Broker Name	Broker Address		Broker Name	Broker Address
THE BANK OF NEW YORK MELLONgceamericas@bnymellon.com	500 GRANT STREET27TH FLOOR PITTSBURGH PAPENNSYLVANIA 15258 US		THE HUNTINGTON NATIONAL BANKhttps://www.huntington.com/customer-service/contact-us	7 EASTON OVAL EA4E62 COLUMBUSOH OHIO 43209 US
THE NORTHERN TRUST COMPANYhttps://www.northerntrust.com/united-states/contact-us-corporate-overview	333 South Wabash Ave, 32nd Floor Attn: Trade Securities Processing CHICAGOIL ILLINOIS 60603 US		TRADESTATION SECURITIES, INCcorpactions@tradestation.com	120 RIVERSIDE PLAZASUITE 1650 CHICAGO IL ILLINOIS 60606 US
U.S. BANCORP INVESTMENTS, INC.corporateactions@usbank.com	60 LIVINGSTON AVEEP-MN-WN1B ST. PAULMN MINNESOTA 55107-1419 US		U.S. BANK N.A./ETFhttps://www.usbank.com/investment-services/contact-us.html	1555 N RIVER CENTER DRIVE MILWAUKEE WI WISCONSIN 53212
U.S. BANK NATIONAL ASSOCIATIONhttps://www.usbank.com/investment-services/contact-us.html	1555 NORTH RIVERCENTER DRIVE, SUITE 302SUITE 302 MILWAUKEEWI WISCONSIN 53212 US		UBS AGhttps://www.ubs.com/global/en/our-firm/locations.html	480 WASHINGTON BLVD.12TH FLOOR JERSEY CITY NJ NEW JERSEY 07310 US
UBS FINANCIAL SERVICES INC.comments@ubs.com	1000 HARBOR BOULEVARD WEEHAWKEN NJ NEW JERSEY07086 US		UBS SECURITIES LLChttps://www.ubs.com/us/en/wealth-management/contact-us.html	677 WASHINGTON BLVDSTAMFORDCT CONNECTICUT 06901 US

Broker Name	Broker Address		Broker Name	Broker Address
UMB BANK, NATIONAL ASSOCIATIONshareholder@computershare.com	928 GRAND BLVD KANSAS CITY MO MISSOURI 64106 US		VANGUARD MARKETING CORPORATIONhttps://corporate.vanguard.com/content/corporatesite/us/en/corp/contact-us.html	100 VANGUARD BLVD MALVERNPA PENNSYLVANIA 19355 US
VELOCITY CLEARING, LLCChristopher.Felicetti@velocityclearingllc.com	1301 Route 36Suite 109 (Attn: Chris Felicetti)HAZLETNEW JERSEY 7730 US		VELOX CLEARING LLCdl-operations@velox-global.com	2400 E. KATELLA AVENUESUITE 725A ANAHEIMCA CALIFORNIA 92806 US
VIRTU AMERICAS LLCinvestor_relations@virtu.com	ONE LIBERTY PLAZA, 165 BROADWAY 5TH FLOOR NEW YORK NY NEW YORK10006 US		VISION FINANCIAL MARKETS LLCsecuritiesops@vfmarkets.com	4 HIGH RIDGE PARK SUITE 100 STAMFORDCT CONNECTICUT 06905 US
WEDBUSH SECURITIES INCreorg@wedbush.com	1000 WILSHIRE BLVD8TH FLOOR LOS ANGELESCA CALIFORNIA90017 US		WEDBUSH SECURITIES INC.reorg@wedbush.com	1000 WILSHIRE BLVD.LOS ANGELES CA CALIFORNIA 90017 US
WELLS FARGO BANK, N.A./SIGhttps://www.wellsfargo.com/help/contact-us/	733 MARQUETTE AVE 4TH FLOOR MAC N9306-04D MINNEAPOLISMN MINNESOTA 55402 US		WELLS FARGO CLEARING SERVICES LLChttps://www.wellsfargo.com/help/contact-us/	1 NORTH JEFFERSON MAIL CODE: H0006- 094ST. LOUISMO MISSOURI 63103 US
WELLS FARGO SECURITIES, LLChttps://www.wellsfargo.com/help/contact-us/	1525 WEST W T HARRIS BLVD CHARLOTTE NC NORTH CAROLINA28262 US		WILSON-DAVIS & CO., INC.dfurlow@wdco.com	236 SOUTH MAIN STREETSALT LAKE CITY UT UTAH84101 US

About Sorrento Therapeutics, Inc.

Sorrento is a clinical and commercial stage biopharmaceutical company developing new therapies to treat cancer, pain (non-opioid treatments), autoimmune disease and COVID-19. Sorrento's multimodal, multipronged approach to fighting cancer is made possible by its extensive immuno-oncology platforms, including key assets such as Abivertinib, next-generation tyrosine kinase inhibitors (“TKIs”), fully human antibodies (“G-MAB™ library”), immuno-cellular therapies (“DAR-T™”), antibody-drug conjugates (“ADCs”), and oncolytic virus (“Seprehvec™”). Sorrento is also developing potential antiviral therapies and vaccines against coronaviruses, including STI-1558, COVI-MSC™; and diagnostic test solutions, including COVIMARK™.

Sorrento's commitment to life-enhancing therapies for patients is also demonstrated by our effort to advance a TRPV1 agonist, non-opioid pain management small molecule, resiniferatoxin (“RTX”), and SP-102 (10 mg, dexamethasone sodium phosphate viscous gel) (SEMDEXA™), a novel, viscous gel formulation of a widely used corticosteroid for epidural injections to treat lumbosacral radicular pain, or sciatica, and to commercialize ZTlido® (lidocaine topical system) 1.8% for the treatment of postherpetic neuralgia (PHN). RTX has been cleared for a Phase II trial for intractable pain associated with cancer and a Phase II trial in osteoarthritis patients. Positive final results from the Phase III Pivotal Trial C.L.E.A.R. Program for SEMDEXA™, its novel, non-opioid product for the treatment of lumbosacral radicular pain (sciatica), were announced in March 2022. ZTlido® was approved by the FDA on February 28, 2018.

For more information visit www.sorrentotherapeutics.com

Media and Investor RelationsContact: Brian CooleyEmail: mediarelations@sorrentotherapeutics.com

Sorrento® and the Sorrento logo are registered trademarks of Sorrento Therapeutics, Inc.G-MAB™, DAR-T™, Seprehvec™, SOFUSA™, COVI-MSC™, COVIMARK™, Ovydso™ and Fujovee™ are trademarks of Sorrento Therapeutics, Inc.SEMDEXA™ (SP-102) is a trademark of Semnur Pharmaceuticals, Inc. A proprietary name review by the FDA is planned.ZTlido® is a registered trademark owned by Scilex Pharmaceuticals Inc. All other trademarks are the property of their respective owners.©2023 Sorrento Therapeutics, Inc. All Rights Reserved.