Adolor Corporation to Host Investor Conference Call to Report Second Quarter 2009 Financial Results

Adolor Corporation (Nasdaq:ADLR) today announced that it will hold a conference call at 9:00 a.m. EDT on Wednesday, July 29, 2009, to discuss second quarter 2009 financial results.

To participate in the audio portion and have the opportunity to pose questions, dial (866) 394-4329 for domestic callers or (706) 902-1952 for international callers, and enter Conference ID # 21182551. Investors also can listen to the call live by logging on to the Company�s website at www.adolor.com and clicking on �Investor Insights,� then "Calendar of Events."

A replay of the call will be available beginning approximately two hours after the event. To listen to a replay of the conference call, dial (800) 642-1687 (domestic) or (706) 645-9291 (international) and enter Conference ID # 21182551 or listen via Adolor�s website. The replay will be available for one week.

About Adolor Corporation

Adolor Corporation is a biopharmaceutical company specializing in the discovery, development and commercialization of novel prescription pain management products.

Adolor�s first approved product in the United States is ENTEREG� (alvimopan), which is indicated to accelerate the time to upper and lower gastrointestinal recovery following partial large or small bowel resection surgery with primary anastomosis. ENTEREG is available for short-term use in hospitals registered under the E.A.S.E.� Program. For more information on ENTEREG, including its full prescribing information, visit www.ENTEREG.com. In collaboration with GlaxoSmithKline (GSK), the Company launched ENTEREG in mid-2008.

The Company�s research and development pipeline includes: two novel delta opioid receptor agonists, currently in mid-stage clinical development in collaboration with Pfizer Inc. for chronic pain; a peripheral mu opioid receptor antagonist entering development for chronic opioid bowel dysfunction (OBD); and several opioid and non-opioid discovery programs.

For more information, visit www.adolor.com.

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